-
1
-
-
58049220365
-
Pattern recognition receptors and control of adaptive immunity
-
Palm NW, Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol Rev 2009;227:221-33.
-
(2009)
Immunol Rev.
, vol.227
, pp. 221-233
-
-
Palm, N.W.1
Medzhitov, R.2
-
3
-
-
77249118801
-
The inflammasomes: mechanisms of activation and function
-
Latz E. The inflammasomes: mechanisms of activation and function. Curr Opin Immunol 2010;22:28-33.
-
(2010)
Curr. Opin Immunol
, vol.22
, pp. 28-33
-
-
Latz, E.1
-
5
-
-
67650736238
-
Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)
-
Masters SL, Simon A, Aksentijevich I, Kastner DL. Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*) Annu Rev Immunol 2009;27:621-68.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 621-668
-
-
Masters, S.L.1
Simon, A.2
Aksentijevich, I.3
Kastner, D.L.4
-
6
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004;20:319-25.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
8
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, et al. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem 2006;281:36560-8.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
Franchi, L.6
-
9
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006;440:228-32.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
10
-
-
32944468985
-
Gout associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Pétrilli V, Mayor A, Tardivel A, Tschopp J. Gout associated uric acid crystals activate the NALP3 inflammasome. Nature 2006;440:237-41.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Pétrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
11
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006;24:317-27.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
-
12
-
-
79960920271
-
NLRP3 inflammasomes link inflammation and metabolic disease
-
De Nardo D, Latz E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends Immunol 2011;32:373-9.
-
(2011)
Trends Immunol
, vol.32
, pp. 373-379
-
-
De Nardo, D.1
Latz, E.2
-
13
-
-
74549184092
-
The NLRP3 inflammasome: a sensor for metabolic danger?
-
Schroder K, Zhou R, Tschopp J. The NLRP3 inflammasome: a sensor for metabolic danger? Science 2010;327:296-300.
-
(2010)
Science
, vol.327
, pp. 296-300
-
-
Schroder, K.1
Zhou, R.2
Tschopp, J.3
-
14
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozören N, Jagirdar R, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 2006;7:576-82.
-
(2006)
Nat. Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozören, N.5
Jagirdar, R.6
-
15
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 2009;459:433-6.
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschläger, N.5
Endres, S.6
-
16
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009;15:1170-8.
-
(2009)
Nat. Med.
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
-
17
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011;469:221-5.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
18
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 2011;12:222-30.
-
(2011)
Nat. Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
-
19
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol 2008;9:857-65.
-
(2008)
Nat. Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
-
20
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 2008;9:847-56.
-
(2008)
Nat. Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
-
21
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Pétrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 2007;14:1583-9.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Pétrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
22
-
-
0038687082
-
Interleukin-18 and host defense against infection
-
Dinarello CA, Fantuzzi G. Interleukin-18 and host defense against infection. J Infect Dis 2003;187 Suppl 2:S370-84.
-
(2003)
J. Infect Dis.
, vol.187
, Issue.SUPPL 2
-
-
Dinarello, C.A.1
Fantuzzi, G.2
-
23
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009;27:519-50.
-
(2009)
Annu. Rev. Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
24
-
-
65549154784
-
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
-
Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, Brown GD, et al. An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans. Cell Host Microbe 2009;5:487-97.
-
(2009)
Cell Host Microbe.
, vol.5
, pp. 487-497
-
-
Hise, A.G.1
Tomalka, J.2
Ganesan, S.3
Patel, K.4
Hall, B.A.5
Brown, G.D.6
-
25
-
-
70349317039
-
Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
-
Joly S, Ma N, Sadler JJ, Soll DR, Cassel SL, Sutterwala FS. Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J Immunol 2009;183:3578-81.
-
(2009)
J. Immunol
, vol.183
, pp. 3578-3581
-
-
Joly, S.1
Ma, N.2
Sadler, J.J.3
Soll, D.R.4
Cassel, S.L.5
Sutterwala, F.S.6
-
26
-
-
76249084408
-
Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan
-
Kumar H, Kumagai Y, Tsuchida T, Koenig PA, Satoh T, Guo Z, et al. Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan. J Immunol 2009;183:8061-7.
-
(2009)
J. Immunol
, vol.183
, pp. 8061-8067
-
-
Kumar, H.1
Kumagai, Y.2
Tsuchida, T.3
Koenig, P.A.4
Satoh, T.5
Guo, Z.6
-
27
-
-
77954958602
-
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase
-
Saïd-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS One 2010;5:e10008.
-
(2010)
PLoS One
, vol.5
-
-
Saïd-Sadier, N.1
Padilla, E.2
Langsley, G.3
Ojcius, D.M.4
-
28
-
-
77953464750
-
(1 3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages
-
Kankkunen P, Teirilä L, Rintahaka J, Alenius H, Wolff H, Matikainen S. (1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages. J Immunol 2010;184:6335-42.
-
(2010)
J. Immunol
, vol.184
, pp. 6335-6342
-
-
Kankkunen, P.1
Teirilä, L.2
Rintahaka, J.3
Alenius, H.4
Wolff, H.5
Matikainen, S.6
-
29
-
-
70449360107
-
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
-
Craven RR, Gao X, Allen IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, et al. Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One 2009;4:e7446.
-
(2009)
PLoS One
, vol.4
-
-
Craven, R.R.1
Gao, X.2
Allen, I.C.3
Gris, D.4
Bubeck Wardenburg, J.5
McElvania-Tekippe, E.6
-
30
-
-
77749270973
-
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor
-
Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol 2009;183:5823-9.
-
(2009)
J. Immunol
, vol.183
, pp. 5823-5829
-
-
Harder, J.1
Franchi, L.2
Muñoz-Planillo, R.3
Park, J.H.4
Reimer, T.5
Núñez, G.6
-
31
-
-
77954521853
-
Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling
-
Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, et al. Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling. J Immunol 2010;184:5287-97.
-
(2010)
J. Immunol
, vol.184
, pp. 5287-5297
-
-
Toma, C.1
Higa, N.2
Koizumi, Y.3
Nakasone, N.4
Ogura, Y.5
McCoy, A.J.6
-
32
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol 2006;7:569-75.
-
(2006)
Nat. Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
-
33
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med 2010;207:1745-55.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
34
-
-
84855272667
-
Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious
-
Ceballos-Olvera I, Sahoo M, Miller MA, Del Barrio L, Re F. Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious. PLoS Pathog 2011;7:e1002452.
-
(2011)
PLoS Pathog
, vol.7
-
-
Ceballos-Olvera, I.1
Sahoo, M.2
Miller, M.A.3
Del Barrio, L.4
Re, F.5
-
35
-
-
70449448992
-
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome
-
Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, et al. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol 2009;182:6460-9.
-
(2009)
J. Immunol
, vol.182
, pp. 6460-6469
-
-
Duncan, J.A.1
Gao, X.2
Huang, M.T.3
O'Connor, B.P.4
Thomas, C.E.5
Willingham, S.B.6
-
36
-
-
35948943102
-
Interleukin-1 is the initiator of Fallopian tube destruction during Chlamydia trachomatis infection
-
Hvid M, Baczynska A, Deleuran B, Fedder J, Knudsen HJ, Christiansen G, et al. Interleukin-1 is the initiator of Fallopian tube destruction during Chlamydia trachomatis infection. Cell Microbiol 2007;9:2795-803.
-
(2007)
Cell Microbiol
, vol.9
, pp. 2795-2803
-
-
Hvid, M.1
Baczynska, A.2
Deleuran, B.3
Fedder, J.4
Knudsen, H.J.5
Christiansen, G.6
-
37
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, et al. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol 2010;11:385-93.
-
(2010)
Nat. Immunol
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
Wu, J.6
-
38
-
-
80655125021
-
Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation
-
Atianand MK, Duffy EB, Shah A, Kar S, Malik M, Harton JA. Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation. J Biol Chem 2011;286:39033-42.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 39033-39042
-
-
Atianand, M.K.1
Duffy, E.B.2
Shah, A.3
Kar, S.4
Malik, M.5
Harton, J.A.6
-
39
-
-
41849104578
-
Mycobacterium tuberculosis prevents inflammasome activation
-
Master SS, Rampini SK, Davis AS, Keller C, Ehlers S, Springer B, et al. Mycobacterium tuberculosis prevents inflammasome activation. Cell Host Microbe 2008;3:224-32.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 224-232
-
-
Master, S.S.1
Rampini, S.K.2
Davis, A.S.3
Keller, C.4
Ehlers, S.5
Springer, B.6
-
40
-
-
77957133396
-
Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
-
Mishra BB, Moura-Alves P, Sonawane A, Hacohen N, Griffiths G, Moita LF, et al. Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell Microbiol 2010;12:1046-63.
-
(2010)
Cell Microbiol.
, vol.12
, pp. 1046-1063
-
-
Mishra, B.B.1
Moura-Alves, P.2
Sonawane, A.3
Hacohen, N.4
Griffiths, G.5
Moita, L.F.6
-
41
-
-
77957908944
-
Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1
-
McElvania Tekippe E, Allen IC, Hulseberg PD, Sullivan JT, McCann JR, Sandor M, et al. Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1. PLoS One 2010;5:e12320.
-
(2010)
PLoS One
, vol.5
-
-
McElvania Tekippe, E.1
Allen, I.C.2
Hulseberg, P.D.3
Sullivan, J.T.4
McCann, J.R.5
Sandor, M.6
-
42
-
-
84856033488
-
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis
-
Dorhoi A, Nouailles G, Jörg S, Hagens K, Heinemann E, Pradl L, et al. Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis. Eur J Immunol 2012;42:374-84.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 374-384
-
-
Dorhoi, A.1
Nouailles, G.2
Jörg, S.3
Hagens, K.4
Heinemann, E.5
Pradl, L.6
-
43
-
-
80051810145
-
Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis
-
Wong KW, Jacobs WR Jr. Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis. Cell Microbiol 2011;13:1371-84.
-
(2011)
Cell Microbiol.
, vol.13
, pp. 1371-1384
-
-
Wong, K.W.1
Jacobs Jr, W.R.2
-
44
-
-
84863726706
-
Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin- 1-Syk and p62/SQSTM1
-
Aug 30 [Epub]. DOI:10.1038/icb.2011.72
-
Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, et al. Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin- 1-Syk and p62/SQSTM1. Immunol Cell Biol 2011 Aug 30 [Epub]. DOI:10.1038/icb.2011.72.
-
(2011)
Immunol Cell Biol.
-
-
Lee, H.M.1
Yuk, J.M.2
Kim, K.H.3
Jang, J.4
Kang, G.5
Park, J.B.6
-
45
-
-
77954050777
-
Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection
-
Carlsson F, Kim J, Dumitru C, Barck KH, Carano RA, Sun M, et al. Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog 2010;6:e1000895.
-
(2010)
PLoS Pathog
, vol.6
-
-
Carlsson, F.1
Kim, J.2
Dumitru, C.3
Barck, K.H.4
Carano, R.A.5
Sun, M.6
-
46
-
-
79955370281
-
The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection
-
Rajan JV, Rodriguez D, Miao EA, Aderem A. The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection. J Virol 2011;85:4167-72.
-
(2011)
J. Virol.
, vol.85
, pp. 4167-4172
-
-
Rajan, J.V.1
Rodriguez, D.2
Miao, E.A.3
Aderem, A.4
-
47
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol 2010;11:63-9.
-
(2010)
Nat. Immunol
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
-
48
-
-
84856249966
-
TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection
-
Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, et al. TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection. PLoS One 2012;7:e29695.
-
(2012)
PLoS One
, vol.7
-
-
Segovia, J.1
Sabbah, A.2
Mgbemena, V.3
Tsai, S.Y.4
Chang, T.H.5
Berton, M.T.6
-
49
-
-
84855919439
-
Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex
-
Burdette D, Haskett A, Presser L, McRae S, Iqbal J, Waris G. Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex. J Gen Virol 2012;93(Pt 2):235-46.
-
(2012)
J. Gen. Virol.
, vol.93
, Issue.PART 2
, pp. 235-246
-
-
Burdette, D.1
Haskett, A.2
Presser, L.3
McRae, S.4
Iqbal, J.5
Waris, G.6
-
50
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Bürckstümmer T, Baumann C, Blüml S, Dixit E, Dürnberger G, Jahn H, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 2009;10:266-72.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 266-272
-
-
Bürckstümmer, T.1
Baumann, C.2
Blüml, S.3
Dixit, E.4
Dürnberger, G.5
Jahn, H.6
-
51
-
-
79955961661
-
Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complex
-
Nour AM, Reichelt M, Ku CC, Ho MY, Heineman TC, Arvin AM. Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complex. J Biol Chem 2011;286:17921-33.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17921-17933
-
-
Nour, A.M.1
Reichelt, M.2
Ku, C.C.3
Ho, M.Y.4
Heineman, T.C.5
Arvin, A.M.6
-
52
-
-
67650915065
-
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6 MDA-5 and the NALP3 inflammasome
-
Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, Akira S, et al. Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog 2009;5:e1000480.
-
(2009)
PLoS Pathog
, vol.5
-
-
Delaloye, J.1
Roger, T.2
Steiner-Tardivel, Q.G.3
Le Roy, D.4
Knaup Reymond, M.5
Akira, S.6
-
53
-
-
77954084102
-
A 3'UTR SNP in NLRP3 gene is associated with susceptibility to HIV-1 infection
-
Pontillo A, Brandão LA, Guimarães RL, Segat L, Athanasakis E, Crovella S. A 3'UTR SNP in NLRP3 gene is associated with susceptibility to HIV-1 infection. J Acquir Immune Defic Syndr 2010;54:236-40.
-
(2010)
J. Acquir Immune Defic Syndr.
, vol.54
, pp. 236-240
-
-
Pontillo, A.1
Brandão, L.A.2
Guimarães, R.L.3
Segat, L.4
Athanasakis, E.5
Crovella, S.6
-
54
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001;29:301-5.
-
(2001)
Nat. Genet.
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
55
-
-
0036302235
-
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
-
Feldmann J, Prieur AM, Quartier P, Berquin P, Certain S, Cortis E, et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am J Hum Genet 2002;71:198-203.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 198-203
-
-
Feldmann, J.1
Prieur, A.M.2
Quartier, P.3
Berquin, P.4
Certain, S.5
Cortis, E.6
-
56
-
-
2542452727
-
Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC
-
Dowds TA, Masumoto J, Zhu L, Inohara N, Núñez G. Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. J Biol Chem 2004;279:21924-8.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21924-21928
-
-
Dowds, T.A.1
Masumoto, J.2
Zhu, L.3
Inohara, N.4
Núñez, G.5
-
57
-
-
0016479801
-
Current concepts of the mechanism of acute inflammation in gouty arthritis
-
Spilberg I. Current concepts of the mechanism of acute inflammation in gouty arthritis. Arthritis Rheum 1975;18:129-34.
-
(1975)
Arthritis Rheum
, vol.18
, pp. 129-134
-
-
Spilberg, I.1
-
58
-
-
58249116545
-
Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout
-
Martin WJ, Walton M, Harper J. Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout. Arthritis Rheum 2009;60:281-9.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 281-289
-
-
Martin, W.J.1
Walton, M.2
Harper, J.3
-
59
-
-
70349379884
-
Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis
-
Torres R, Macdonald L, Croll SD, Reinhardt J, Dore A, Stevens S, et al. Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Ann Rheum Dis 2009;68:1602-8.
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1602-1608
-
-
Torres, R.1
Macdonald, L.2
Croll, S.D.3
Reinhardt, J.4
Dore, A.5
Stevens, S.6
-
60
-
-
34548667797
-
Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra
-
McGonagle D, Tan AL, Shankaranarayana S, Madden J, Emery P, McDermott MF. Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra. Ann Rheum Dis 2007;66:1683-4.
-
(2007)
Ann. Rheum. Dis.
, vol.66
, pp. 1683-1684
-
-
McGonagle, D.1
Tan, A.L.2
Shankaranarayana, S.3
Madden, J.4
Emery, P.5
McDermott, M.F.6
-
62
-
-
65649140025
-
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
-
Gasse P, Riteau N, Charron S, Girre S, Fick L, Pétrilli V, et al. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med 2009;179:903-13.
-
(2009)
Am. J. Respir Crit. Care Med.
, vol.179
, pp. 903-913
-
-
Gasse, P.1
Riteau, N.2
Charron, S.3
Girre, S.4
Fick, L.5
Pétrilli, V.6
-
63
-
-
0033552883
-
Atherosclerosis: an inflammatory disease
-
Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999;340:115-26.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
65
-
-
77956663452
-
Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation
-
Abela GS. Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation. J Clin Lipidol 2010;4:156-64.
-
(2010)
J. Clin. Lipidol
, vol.4
, pp. 156-164
-
-
Abela, G.S.1
-
66
-
-
79955031540
-
Inflammatory markers and cardiovascular risk in the metabolic syndrome
-
Espinola-Klein C, Gori T, Blankenberg S, Munzel T. Inflammatory markers and cardiovascular risk in the metabolic syndrome. Front Biosci 2011;16:1663-74.
-
(2011)
Front Biosci.
, vol.16
, pp. 1663-1674
-
-
Espinola-Klein, C.1
Gori, T.2
Blankenberg, S.3
Munzel, T.4
-
67
-
-
77954726266
-
Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome
-
He X, Mekasha S, Mavrogiorgos N, Fitzgerald KA, Lien E, Ingalls RR. Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome. J Immunol 2010;184:5743-54.
-
(2010)
J. Immunol.
, vol.184
, pp. 5743-5754
-
-
He, X.1
Mekasha, S.2
Mavrogiorgos, N.3
Fitzgerald, K.A.4
Lien, E.5
Ingalls, R.R.6
-
68
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 2010;464:1357-61.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
-
69
-
-
77955356552
-
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation
-
Rajamäki K, Lappalainen J, Oörni K, Välimäki E, Matikainen S, Kovanen PT, et al. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS One 2010;5:e11765.
-
(2010)
PLoS One
, vol.5
-
-
Rajamäki, K.1
Lappalainen, J.2
Oörni, K.3
Välimäki, E.4
Matikainen, S.5
Kovanen, P.T.6
-
70
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444:840-6.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
71
-
-
0345700727
-
Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
-
Spranger J, Kroke A, Möhlig M, Hoffmann K, Bergmann MM, Ristow M, et al. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 2003;52:812-7.
-
(2003)
Diabetes
, vol.52
, pp. 812-817
-
-
Spranger, J.1
Kroke, A.2
Möhlig, M.3
Hoffmann, K.4
Bergmann, M.M.5
Ristow, M.6
-
72
-
-
25844489169
-
Elevated levels of interleukin-18 predict the development of type 2 diabetes: results from the MONICA/KORA Augsburg Study 1984-2002
-
Thorand B, Kolb H, Baumert J, Koenig W, Chambless L, Meisinger C, et al. Elevated levels of interleukin-18 predict the development of type 2 diabetes: results from the MONICA/KORA Augsburg Study, 1984-2002. Diabetes 2005;54:2932-8.
-
(2005)
Diabetes
, vol.54
, pp. 2932-2938
-
-
Thorand, B.1
Kolb, H.2
Baumert, J.3
Koenig, W.4
Chambless, L.5
Meisinger, C.6
-
73
-
-
0022445268
-
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans
-
Bendtzen K, Mandrup-Poulsen T, Nerup J, Nielsen JH, Dinarello CA, Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science 1986;232:1545-7.
-
(1986)
Science
, vol.232
, pp. 1545-1547
-
-
Bendtzen, K.1
Mandrup-Poulsen, T.2
Nerup, J.3
Nielsen, J.H.4
Dinarello, C.A.5
Svenson, M.6
-
74
-
-
71949118923
-
Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I
-
Böni-Schnetzler M, Boller S, Debray S, Bouzakri K, Meier DT, Prazak R, et al. Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I. Endocrinology 2009;150:5218-29.
-
(2009)
Endocrinology
, vol.150
, pp. 5218-5229
-
-
Böni-Schnetzler, M.1
Boller, S.2
Debray, S.3
Bouzakri, K.4
Meier, D.T.5
Prazak, R.6
-
76
-
-
69549098032
-
IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
-
Ehses JA, Lacraz G, Giroix MH, Schmidlin F, Coulaud J, Kassis N, et al. IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat. Proc Natl Acad Sci U S A 2009;106:13998-4003.
-
(2009)
Proc. Natl. Acad Sci. U S A
, vol.106
, pp. 13998-14003
-
-
Ehses, J.A.1
Lacraz, G.2
Giroix, M.H.3
Schmidlin, F.4
Coulaud, J.5
Kassis, N.6
-
77
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease
-
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011;11:98-107.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
78
-
-
0023579739
-
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
-
Cooper GJ, Willis AC, Clark A, Turner RC, Sim RB, Reid KB. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci U S A 1987;84:8628-32.
-
(1987)
Proc. Natl. Acad Sci. U S A
, vol.84
, pp. 8628-8632
-
-
Cooper, G.J.1
Willis, A.C.2
Clark, A.3
Turner, R.C.4
Sim, R.B.5
Reid, K.B.6
-
79
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
-
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes. Nat Immunol 2010;11:897-904.
-
(2010)
Nat. Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
-
80
-
-
80052650475
-
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction
-
Westwell-Roper C, Dai DL, Soukhatcheva G, Potter KJ, van Rooijen N, Ehses JA, et al. IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction. J Immunol 2011;187:2755-65.
-
(2011)
J. Immunol
, vol.187
, pp. 2755-2765
-
-
Westwell-Roper, C.1
Dai, D.L.2
Soukhatcheva, G.3
Potter, K.J.4
van Rooijen, N.5
Ehses, J.A.6
-
81
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2010;11:136-40.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
82
-
-
77449151150
-
Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death
-
Chen J, Fontes G, Saxena G, Poitout V, Shalev A. Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death. Diabetes 2010;59:440-7.
-
(2010)
Diabetes
, vol.59
, pp. 440-447
-
-
Chen, J.1
Fontes, G.2
Saxena, G.3
Poitout, V.4
Shalev, A.5
-
83
-
-
77950345571
-
CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes
-
Komura T, Sakai Y, Honda M, Takamura T, Matsushima K, Kaneko S. CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes. Diabetes 2010;59:634-43.
-
(2010)
Diabetes
, vol.59
, pp. 634-643
-
-
Komura, T.1
Sakai, Y.2
Honda, M.3
Takamura, T.4
Matsushima, K.5
Kaneko, S.6
-
84
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
Menu P, Mayor A, Zhou R, Tardivel A, Ichijo H, Mori K, et al. ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis 2012;3:e261.
-
(2012)
Cell Death Dis.
, vol.3
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
-
85
-
-
0032703264
-
Treatment of rheumatoid arthritis with interleukin 1 receptor antagonist
-
Bresnihan B. Treatment of rheumatoid arthritis with interleukin 1 receptor antagonist. Ann Rheum Dis 1999;58 Suppl 1:I96-8.
-
(1999)
Ann. Rheum Dis.
, vol.58
, Issue.SUPPL 1
-
-
Bresnihan, B.1
-
87
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
-
Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, et al. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 2004;364:1779-85.
-
(2004)
Lancet
, vol.364
, pp. 1779-1785
-
-
Hoffman, H.M.1
Rosengren, S.2
Boyle, D.L.3
Cho, J.Y.4
Nayar, J.5
Mueller, J.L.6
-
88
-
-
49449094179
-
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies
-
Hoffman HM, Throne ML, Amar NJ, Sebai M, Kivitz AJ, Kavanaugh A, et al. Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies. Arthritis Rheum 2008;58:2443-52.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2443-2452
-
-
Hoffman, H.M.1
Throne, M.L.2
Amar, N.J.3
Sebai, M.4
Kivitz, A.J.5
Kavanaugh, A.6
-
89
-
-
79551705915
-
Gout in 2010 progress and controversies in treatment
-
Dalbeth N. Gout in 2010: progress and controversies in treatment. Nat Rev Rheumatol 2011;7:77-8.
-
(2011)
Nat. Rev. Rheumatol
, vol.7
, pp. 77-78
-
-
Dalbeth, N.1
-
90
-
-
70349402166
-
The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
-
Terkeltaub R, Sundy JS, Schumacher HR, Murphy F, Bookbinder S, Biedermann S, et al. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis 2009;68:1613-7.
-
(2009)
Ann. Rheum Dis.
, vol.68
, pp. 1613-1617
-
-
Terkeltaub, R.1
Sundy, J.S.2
Schumacher, H.R.3
Murphy, F.4
Bookbinder, S.5
Biedermann, S.6
-
91
-
-
77957688721
-
Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: results of a multicenter, phase II, dose-ranging study
-
So A, De Meulemeester M, Pikhlak A, Yücel AE, Richard D, Murphy V, et al. Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: results of a multicenter, phase II, dose-ranging study. Arthritis Rheum 2010;62:3064-76.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3064-3076
-
-
So, A.1
De Meulemeester, M.2
Pikhlak, A.3
Yücel, A.E.4
Richard, D.5
Murphy, V.6
-
92
-
-
39749175570
-
Successful treatment of resistant pseudogout with anakinra
-
McGonagle D, Tan AL, Madden J, Emery P, McDermott MF. Successful treatment of resistant pseudogout with anakinra. Arthritis Rheum 2008;58:631-3.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 631-633
-
-
McGonagle, D.1
Tan, A.L.2
Madden, J.3
Emery, P.4
McDermott, M.F.5
-
93
-
-
23444439667
-
IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients
-
Stack JH, Beaumont K, Larsen PD, Straley KS, Henkel GW, Randle JC, et al. IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients. J Immunol 2005;175:2630-4.
-
(2005)
J. Immunol
, vol.175
, pp. 2630-2634
-
-
Stack, J.H.1
Beaumont, K.2
Larsen, P.D.3
Straley, K.S.4
Henkel, G.W.5
Randle, J.C.6
-
94
-
-
77952287367
-
Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome
-
Mitroulis I, Skendros P, Ritis K. Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome. Eur J Intern Med 2010;21:157-63.
-
(2010)
Eur. J. Intern. Med.
, vol.21
, pp. 157-163
-
-
Mitroulis, I.1
Skendros, P.2
Ritis, K.3
|