Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR

Journal of Biological Chemistry

Volumn 285, Issue 47, 2010, Pages 36387-36394

  Liu, Meilian ^a   Wilk, Sarah Ann ^a   Wang, Anping ^a   Zhou, Lijun ^a   Wang, Rui Hong ^c   Ogawa, Wataru ^d   Deng, Chuxia ^c   Dong, Lily Q ^a,b   Liu, Feng ^a,b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMP-ACTIVATED PROTEIN KINASE; ANTI-INFLAMMATORIES; C2C12 CELLS; EXPRESSION LEVELS; HEALTH EFFECTS; IN-CELL; INHIBITORY EFFECT; INHIBITORY SITES; INSULIN RECEPTORS; MOUSE EMBRYONIC FIBROBLASTS; MTOR SIGNALING; NATURALLY OCCURRING; POLYPHENOLS; RESVERATROL; S6 KINASE; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; CELL CULTURE; ENZYME ACTIVITY; FIBROBLASTS; INSULIN; PHOSPHORYLATION; SIGNALING;

ANTIBIOTICS;

BINDING PROTEIN; DEP DOMAIN CONTAINING AND MAMMALIAN TARGET OF RAPAMYCIN INTERACTING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 4E BINDING PROTEIN 1; INSULIN; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; POLYPHENOL; PROTEIN KINASE B; RESVERATROL; S6 KINASE; SIRTUIN 1; TUBERIN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; FIBROBLAST; INHIBITION KINETICS; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; CELLS, CULTURED; EMBRYO, MAMMALIAN; FIBROBLASTS; IMMUNOPRECIPITATION; LEUCINE; MICE; MICE, KNOCKOUT; MYOBLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SIRTUIN 1; STILBENES; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; VASODILATOR AGENTS;

RICE STRIPE VIRUS;

EID: 78449241484     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.169284     Document Type: Article

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