-
1
-
-
0034661989
-
Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells
-
Philpott DJ, Yamaoka S, Israel A, Sansonetti PJ. Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J Immunol (2000) 165:903-14.
-
(2000)
J Immunol
, vol.165
, pp. 903-914
-
-
Philpott, D.J.1
Yamaoka, S.2
Israel, A.3
Sansonetti, P.J.4
-
2
-
-
33846330896
-
Nod-like proteins in immunity, inflammation and disease
-
doi: 10.1038/ni1412
-
Fritz JH, Ferrero RL, Philpott DJ, Girardin SE. Nod-like proteins in immunity, inflammation and disease. Nat Immunol (2006) 7:1250-7. doi: 10.1038/ni1412
-
(2006)
Nat Immunol
, vol.7
, pp. 1250-1257
-
-
Fritz, J.H.1
Ferrero, R.L.2
Philpott, D.J.3
Girardin, S.E.4
-
3
-
-
84857062410
-
A new eye on NLR proteins: focused on clarity or diffused by complexity?
-
doi:10.1016/j.coi.2011.12.006
-
Bonardi V, Cherkis K, Nishimura MT, Dangl JL. A new eye on NLR proteins: focused on clarity or diffused by complexity? Curr Opin Immunol (2012) 24:41-50. doi:10.1016/j.coi.2011.12.006
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 41-50
-
-
Bonardi, V.1
Cherkis, K.2
Nishimura, M.T.3
Dangl, J.L.4
-
4
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
doi:10.1074/jbc.C200651200
-
Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem (2003) 278:8869-72. doi:10.1074/jbc.C200651200
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
Chamaillard, M.4
Labigne, A.5
Thomas, G.6
-
5
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
doi:10.1074/jbc.C200673200
-
Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, Crespo J, et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem (2003) 278:5509-12. doi:10.1074/jbc.C200673200
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
Crespo, J.6
-
6
-
-
38549167992
-
Nod-like proteins in inflammation and disease
-
doi:10.1002/path.2271
-
Carneiro L, Magalhaes JG, Tattoli I, Philpott DJ, Travassos LH. Nod-like proteins in inflammation and disease. J Pathol (2008) 214:136-48. doi:10.1002/path.2271
-
(2008)
J Pathol
, vol.214
, pp. 136-148
-
-
Carneiro, L.1
Magalhaes, J.G.2
Tattoli, I.3
Philpott, D.J.4
Travassos, L.H.5
-
7
-
-
27744606975
-
Nod1 participates in the innate immune response to Pseudomonas aeruginosa
-
doi:10.1074/jbc.M501649200
-
Travassos LH, Carneiro LAM, Girardin SE, Boneca IG, Lemos R, Bozza MT, et al. Nod1 participates in the innate immune response to Pseudomonas aeruginosa. J Biol Chem (2005) 280:36714-8. doi:10.1074/jbc.M501649200
-
(2005)
J Biol Chem
, vol.280
, pp. 36714-36718
-
-
Travassos, L.H.1
Carneiro, L.A.M.2
Girardin, S.E.3
Boneca, I.G.4
Lemos, R.5
Bozza, M.T.6
-
8
-
-
0038615855
-
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
-
doi:10.1126/science.1084677
-
Girardin SE, Boneca IG, Carneiro LAM, Antignac A, Jéhanno M, Viala J, et al. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science (2003) 300:1584-7. doi:10.1126/science.1084677
-
(2003)
Science
, vol.300
, pp. 1584-1587
-
-
Girardin, S.E.1
Boneca, I.G.2
Carneiro, L.A.M.3
Antignac, A.4
Jéhanno, M.5
Viala, J.6
-
9
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
doi:10.1038/ni945
-
Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol (2003) 4:702-7. doi:10.1038/ni945
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
Saab, L.6
-
10
-
-
12444259829
-
Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2-and NOD1-dependent manner, respectively, in human monocytic cells in culture
-
doi:10.1111/j.1462-5822.2004.00433.x
-
Uehara A, Yang S, Fujimoto Y, Fukase K, Kusumoto S, Shibata K, et al. Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2-and NOD1-dependent manner, respectively, in human monocytic cells in culture. Cell Microbiol (2005) 7:53-61. doi:10.1111/j.1462-5822.2004.00433.x
-
(2005)
Cell Microbiol
, vol.7
, pp. 53-61
-
-
Uehara, A.1
Yang, S.2
Fujimoto, Y.3
Fukase, K.4
Kusumoto, S.5
Shibata, K.6
-
11
-
-
28544434876
-
Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin
-
doi:10.1038/sj.embor.7400552
-
Magalhaes JG, Philpott DJ, Nahori M-A, Jéhanno M, Fritz J, Bourhis LL, et al. Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin. EMBO Rep (2005) 6:1201-7. doi:10.1038/sj.embor.7400552
-
(2005)
EMBO Rep
, vol.6
, pp. 1201-1207
-
-
Magalhaes, J.G.1
Philpott, D.J.2
Nahori, M.-A.3
Jéhanno, M.4
Fritz, J.5
Bourhis, L.L.6
-
12
-
-
33746210219
-
Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1
-
Uehara A, Fujimoto Y, Kawasaki A, Kusumoto S, Fukase K, Takada H. Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1. J Immunol (2006) 177:1796-804.
-
(2006)
J Immunol
, vol.177
, pp. 1796-1804
-
-
Uehara, A.1
Fujimoto, Y.2
Kawasaki, A.3
Kusumoto, S.4
Fukase, K.5
Takada, H.6
-
13
-
-
33749384363
-
Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments
-
doi:10.1074/jbc.M602638200
-
Hasegawa M, Yang K, Hashimoto M, Park J-H, Kim Y-G, Fujimoto Y, et al. Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments. J Biol Chem (2006) 281:29054-63. doi:10.1074/jbc.M602638200
-
(2006)
J Biol Chem
, vol.281
, pp. 29054-29063
-
-
Hasegawa, M.1
Yang, K.2
Hashimoto, M.3
Park, J.-H.4
Kim, Y.-G.5
Fujimoto, Y.6
-
14
-
-
70349433671
-
Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar typhimurium infection
-
doi:10.1128/IAI.00519-09
-
Le Bourhis L, Magalhaes JG, Selvanantham T, Travassos LH, Geddes K, Fritz JH, et al. Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar typhimurium infection. Infect Immun (2009) 77:4480-6. doi:10.1128/IAI.00519-09
-
(2009)
Infect Immun
, vol.77
, pp. 4480-4486
-
-
Le Bourhis, L.1
Magalhaes, J.G.2
Selvanantham, T.3
Travassos, L.H.4
Geddes, K.5
Fritz, J.H.6
-
15
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
doi:10.1038/ni1131
-
Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol (2004) 5:1166-74. doi:10.1038/ni1131
-
(2004)
Nat Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Moran, A.P.6
-
16
-
-
84874099046
-
Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis
-
doi:10.1038/mi.2012.63
-
Kavathas PB, Boeras CM, Mulla MJ, Abrahams VM. Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis. Mucosal Immunol (2013) 6:235-43. doi:10.1038/mi.2012.63
-
(2013)
Mucosal Immunol
, vol.6
, pp. 235-243
-
-
Kavathas, P.B.1
Boeras, C.M.2
Mulla, M.J.3
Abrahams, V.M.4
-
17
-
-
46449093146
-
The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection
-
doi:10.1128/IAI.00104-08
-
Buchholz KR, Stephens RS. The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection. Infect Immun (2008) 76:3150-5. doi:10.1128/IAI.00104-08
-
(2008)
Infect Immun
, vol.76
, pp. 3150-3155
-
-
Buchholz, K.R.1
Stephens, R.S.2
-
18
-
-
33646382812
-
Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum
-
doi:10.1111/j.1462-5822.2006.00686.x
-
Welter-Stahl L, Ojcius DM, Viala J, Girardin S, Liu W, Delarbre C, et al. Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum. Cell Microbiol (2006) 8:1047-57. doi:10.1111/j.1462-5822.2006.00686.x
-
(2006)
Cell Microbiol
, vol.8
, pp. 1047-1057
-
-
Welter-Stahl, L.1
Ojcius, D.M.2
Viala, J.3
Girardin, S.4
Liu, W.5
Delarbre, C.6
-
19
-
-
14044268789
-
Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae
-
doi:10.1161/01.RES.0000155721.83594.2c
-
Opitz B. Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae. Circ Res (2005) 96:319-26. doi:10.1161/01.RES.0000155721.83594.2c
-
(2005)
Circ Res
, vol.96
, pp. 319-326
-
-
Opitz, B.1
-
20
-
-
34250888664
-
Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells
-
Park J-H, Kim Y-G, Shaw M, Kanneganti T-D, Fujimoto Y, Fukase K, et al. Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. J Immunol (2007) 179:514-21.
-
(2007)
J Immunol
, vol.179
, pp. 514-521
-
-
Park, J.-H.1
Kim, Y.-G.2
Shaw, M.3
Kanneganti, T.-D.4
Fujimoto, Y.5
Fukase, K.6
-
21
-
-
56149111709
-
Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages
-
Kim Y-G, Park J-H, Daignault S, Fukase K, Nuñez G. Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages. J Immunol (2008) 181:4340-6.
-
(2008)
J Immunol
, vol.181
, pp. 4340-4346
-
-
Kim, Y.-G.1
Park, J.-H.2
Daignault, S.3
Fukase, K.4
Nuñez, G.5
-
22
-
-
29644434743
-
Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells
-
Opitz B, Püschel A, Beermann W, Hocke AC, Förster S, Schmeck B, et al. Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells. J Immunol (2006) 176:484-90.
-
(2006)
J Immunol
, vol.176
, pp. 484-490
-
-
Opitz, B.1
Püschel, A.2
Beermann, W.3
Hocke, A.C.4
Förster, S.5
Schmeck, B.6
-
23
-
-
1342344961
-
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
-
doi:10.1128/IAI.72.3.1487-1495.2004
-
Kim JG, Lee SJ, Kagnoff MF. Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun (2004) 72:1487-95. doi:10.1128/IAI.72.3.1487-1495.2004
-
(2004)
Infect Immun
, vol.72
, pp. 1487-1495
-
-
Kim, J.G.1
Lee, S.J.2
Kagnoff, M.F.3
-
24
-
-
17944380130
-
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
-
doi:10.1093/embo-reports/kve155
-
Girardin SE, Tournebize R, Mavris M, Page AL, Li X. CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri. EMBO Rep (2001) 2(8):736-42. doi:10.1093/embo-reports/kve155
-
(2001)
EMBO Rep
, vol.2
, Issue.8
, pp. 736-742
-
-
Girardin, S.E.1
Tournebize, R.2
Mavris, M.3
Page, A.L.4
Li, X.5
-
25
-
-
60649120752
-
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells
-
doi:10.1016/j.chom.2008.12.011
-
Carneiro LAM, Travassos LH, Soares F, Tattoli I, Magalhaes JG, Bozza MT, et al. Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell Host Microbe (2009) 5:123-36. doi:10.1016/j.chom.2008.12.011
-
(2009)
Cell Host Microbe
, vol.5
, pp. 123-136
-
-
Carneiro, L.A.M.1
Travassos, L.H.2
Soares, F.3
Tattoli, I.4
Magalhaes, J.G.5
Bozza, M.T.6
-
26
-
-
77955424978
-
Campylobacter jejuni activates NF-kappaB independently of TLR2, TLR4, Nod1 and Nod2 receptors
-
doi:10.1016/j.micpath.2010.06.011
-
Al-Sayeqh AF, Loughlin MF, Dillon E, Mellits KH, Connerton IF. Campylobacter jejuni activates NF-kappaB independently of TLR2, TLR4, Nod1 and Nod2 receptors. Microb Pathog (2010) 49:294-304. doi:10.1016/j.micpath.2010.06.011
-
(2010)
Microb Pathog
, vol.49
, pp. 294-304
-
-
Al-Sayeqh, A.F.1
Loughlin, M.F.2
Dillon, E.3
Mellits, K.H.4
Connerton, I.F.5
-
27
-
-
34548425221
-
A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni
-
doi:10.1111/j.1462-5822.2007.01008.x
-
Zilbauer M, Dorrell N, Elmi A, Lindley KJ, Schüller S, Jones HE, et al. A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. Cell Microbiol (2007) 9:2404-16. doi:10.1111/j.1462-5822.2007.01008.x
-
(2007)
Cell Microbiol
, vol.9
, pp. 2404-2416
-
-
Zilbauer, M.1
Dorrell, N.2
Elmi, A.3
Lindley, K.J.4
Schüller, S.5
Jones, H.E.6
-
28
-
-
77949326831
-
Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection
-
doi:10.4049/jimmunol.0902254
-
Silva GK, Gutierrez FRS, Guedes PMM, Horta CV, Cunha LD, Mineo TWP, et al. Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection. J Immunol (2010) 184:1148-52. doi:10.4049/jimmunol.0902254
-
(2010)
J Immunol
, vol.184
, pp. 1148-1152
-
-
Silva, G.K.1
Gutierrez, F.R.S.2
Guedes, P.M.M.3
Horta, C.V.4
Cunha, L.D.5
Mineo, T.W.P.6
-
29
-
-
70349459620
-
Activation of innate immune antiviral responses by Nod2
-
doi:10.1038/ni.1782
-
Sabbah A, Chang TH, Harnack R, Frohlich V, Tominaga K, Dube PH, et al. Activation of innate immune antiviral responses by Nod2. Nat Immunol (2009) 10:1073-80. doi:10.1038/ni.1782
-
(2009)
Nat Immunol
, vol.10
, pp. 1073-1080
-
-
Sabbah, A.1
Chang, T.H.2
Harnack, R.3
Frohlich, V.4
Tominaga, K.5
Dube, P.H.6
-
30
-
-
84860241844
-
NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans
-
doi:10.1002/eji.201142105
-
Juárez E, Carranza C, Hernández-Sánchez F, León-Contreras JC, Hernández-Pando R, Escobedo D, et al. NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans. Eur J Immunol (2012) 42:880-9. doi:10.1002/eji.201142105
-
(2012)
Eur J Immunol
, vol.42
, pp. 880-889
-
-
Juárez, E.1
Carranza, C.2
Hernández-Sánchez, F.3
León-Contreras, J.C.4
Hernández-Pando, R.5
Escobedo, D.6
-
31
-
-
77951073629
-
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
-
doi:10.1371/journal.ppat.0010034
-
Ferwerda G, Girardin SE, Kullberg B-J, Le Bourhis L, de Jong DJ, Langenberg DML, et al. NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. PLoS Pathog (2005) 1:e34. doi:10.1371/journal.ppat.0010034
-
(2005)
PLoS Pathog
, vol.1
-
-
Ferwerda, G.1
Girardin, S.E.2
Kullberg, B.-J.3
Le Bourhis, L.4
de Jong, D.J.5
Langenberg, D.M.L.6
-
32
-
-
58149189054
-
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity
-
Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, et al. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol (2008) 181:7157-65.
-
(2008)
J Immunol
, vol.181
, pp. 7157-7165
-
-
Divangahi, M.1
Mostowy, S.2
Coulombe, F.3
Kozak, R.4
Guillot, L.5
Veyrier, F.6
-
33
-
-
7944220803
-
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition
-
doi:10.1038/sj.embor.7400248
-
Travassos LH, Girardin SE, Philpott DJ, Blanot D, Nahori M-A, Werts C, et al. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep (2004) 5:1000-6. doi:10.1038/sj.embor.7400248
-
(2004)
EMBO Rep
, vol.5
, pp. 1000-1006
-
-
Travassos, L.H.1
Girardin, S.E.2
Philpott, D.J.3
Blanot, D.4
Nahori, M.-A.5
Werts, C.6
-
34
-
-
77952574671
-
NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae
-
doi:10.1002/glia.20968
-
Liu X, Chauhan VS, Young AB, Marriott I. NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae. Glia (2010) 58:839-47. doi:10.1002/glia.20968
-
(2010)
Glia
, vol.58
, pp. 839-847
-
-
Liu, X.1
Chauhan, V.S.2
Young, A.B.3
Marriott, I.4
-
35
-
-
33646941554
-
Role for erbin in bacterial activation of Nod2
-
doi:10.1128/IAI.00035-06
-
Kufer TA, Kremmer E, Banks DJ, Philpott DJ. Role for erbin in bacterial activation of Nod2. Infect Immun (2006) 74:3115-24. doi:10.1128/IAI.00035-06
-
(2006)
Infect Immun
, vol.74
, pp. 3115-3124
-
-
Kufer, T.A.1
Kremmer, E.2
Banks, D.J.3
Philpott, D.J.4
-
36
-
-
84855221528
-
A Salmonella virulence factor activates the NOD1/NOD2 signaling pathway
-
doi:10.1128/mBio.00266-11
-
Keestra AM, Winter MG, Klein-Douwel D, Xavier MN, Winter SE, Kim A, et al. A Salmonella virulence factor activates the NOD1/NOD2 signaling pathway. MBio (2011) 2(6):e00266-11. doi:10.1128/mBio.00266-11
-
(2011)
MBio
, vol.2
, Issue.6
-
-
Keestra, A.M.1
Winter, M.G.2
Klein-Douwel, D.3
Xavier, M.N.4
Winter, S.E.5
Kim, A.6
-
37
-
-
0037380969
-
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
-
doi:10.1053/gast.2003.50153
-
Hisamatsu T, Suzuki M, Reinecker H-C, Nadeau WJ, McCormick BA, Podolsky DK. CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology (2003) 124:993-1000. doi:10.1053/gast.2003.50153
-
(2003)
Gastroenterology
, vol.124
, pp. 993-1000
-
-
Hisamatsu, T.1
Suzuki, M.2
Reinecker, H.-C.3
Nadeau, W.J.4
McCormick, B.A.5
Podolsky, D.K.6
-
38
-
-
84864007849
-
Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor
-
doi:10.1101/gad.190157.112
-
Kobayashi M, Wilson AC, Chao MV, Mohr I. Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor. Genes Dev (2012) 26:1527-32. doi:10.1101/gad.190157.112
-
(2012)
Genes Dev
, vol.26
, pp. 1527-1532
-
-
Kobayashi, M.1
Wilson, A.C.2
Chao, M.V.3
Mohr, I.4
-
39
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
doi:10.1016/j.cub.2004.10.027
-
Martinon F, Agostini L, Meylan E, Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol (2004) 14(21):1929-34. doi:10.1016/j.cub.2004.10.027
-
(2004)
Curr Biol
, vol.14
, Issue.21
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
40
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
doi:10.1038/nature04517
-
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature (2006) 440(7081):233-6. doi:10.1038/nature04517
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
-
41
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
doi:10.1038/nature04516
-
Martinon F, Pétrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nat Cell Biol (2006) 440:237-41. doi:10.1038/nature04516
-
(2006)
Nat Cell Biol
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Pétrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
42
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
doi:10.1038/nature08938
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature (2010) 464:1357-61. doi:10.1038/nature08938
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
-
43
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
doi:10.1038/ni.1631
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 9:847-56. doi:10.1038/ni.1631
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
-
44
-
-
79954587515
-
Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms
-
doi:10.1016/j.immuni.2011.03.019
-
Kuroda E, Ishii KJ, Uematsu S, Ohata K, Coban C, Akira S, et al. Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms. Immunity (2011) 34:514-26. doi:10.1016/j.immuni.2011.03.019
-
(2011)
Immunity
, vol.34
, pp. 514-526
-
-
Kuroda, E.1
Ishii, K.J.2
Uematsu, S.3
Ohata, K.4
Coban, C.5
Akira, S.6
-
45
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
doi:10.1073/pnas.0803933105
-
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, et al. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A (2008) 105:9035-40. doi:10.1073/pnas.0803933105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9035-9040
-
-
Cassel, S.L.1
Eisenbarth, S.C.2
Iyer, S.S.3
Sadler, J.J.4
Colegio, O.R.5
Tephly, L.A.6
-
46
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
doi:10.1038/ni.1636
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol (2008) 9:857-65. doi:10.1038/ni.1636
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
-
47
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
doi:10.1038/ni.2022
-
Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT-H, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol (2011) 12:408-15. doi:10.1038/ni.2022
-
(2011)
Nat Immunol
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.-H.6
-
48
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
doi:10.1038/ni.1980
-
Nakahira K, Haspel JA, Rathinam VAK, Lee S-J, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol (2011) 12:222-30. doi:10.1038/ni.1980
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.K.3
Lee, S.-J.4
Dolinay, T.5
Lam, H.C.6
-
49
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
doi:10.1016/j.immuni.2012.01.009
-
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity (2012) 36:401-14. doi:10.1016/j.immuni.2012.01.009
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
-
50
-
-
33748598700
-
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
-
doi:10.1016/j.cell.2006.07.033
-
Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell (2006) 126:1135-45. doi:10.1016/j.cell.2006.07.033
-
(2006)
Cell
, vol.126
, pp. 1135-1145
-
-
Gurcel, L.1
Abrami, L.2
Girardin, S.3
Tschopp, J.4
van der Goot, F.G.5
-
51
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
doi:10.1038/nature04515
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 440:228-32. doi:10.1038/nature04515
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
-
52
-
-
70449360107
-
Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
-
doi:10.1371/journal.pone.0007446
-
Craven RR, Gao X, Allen IC, Gris D, Wardenburg JB. Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One (2009) 4(10):e7446. doi:10.1371/journal.pone.0007446
-
(2009)
PLoS One
, vol.4
, Issue.10
-
-
Craven, R.R.1
Gao, X.2
Allen, I.C.3
Gris, D.4
Wardenburg, J.B.5
-
53
-
-
77953305895
-
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome
-
doi:10.1002/eji.201040425
-
Kim S, Bauernfeind F, Ablasser A. Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome. Eur J Immunol (2010) 40:1545-51. doi:10.1002/eji.201040425
-
(2010)
Eur J Immunol
, vol.40
, pp. 1545-1551
-
-
Kim, S.1
Bauernfeind, F.2
Ablasser, A.3
-
54
-
-
61449193203
-
Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells
-
doi:10.4049/jimmunol.0800909
-
Huang MT-H, Taxman DJ, Holley-Guthrie EA, Moore CB, Willingham SB, Madden V, et al. Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells. J Immunol (2009) 182:2395-404. doi:10.4049/jimmunol.0800909
-
(2009)
J Immunol
, vol.182
, pp. 2395-2404
-
-
Huang, M.T.-H.1
Taxman, D.J.2
Holley-Guthrie, E.A.3
Moore, C.B.4
Willingham, S.B.5
Madden, V.6
-
55
-
-
70350366890
-
Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis
-
doi:10.1074/jbc.M109.026823
-
Abdul-Sater AA, Koo E, Häcker G, Ojcius DM. Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. J Biol Chem (2009) 284:26789-96. doi:10.1074/jbc.M109.026823
-
(2009)
J Biol Chem
, vol.284
, pp. 26789-26796
-
-
Abdul-Sater, A.A.1
Koo, E.2
Häcker, G.3
Ojcius, D.M.4
-
56
-
-
77954726266
-
Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome
-
doi:10.4049/jimmunol.0903937
-
He X, Mekasha S, Mavrogiorgos N. Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome. J Immunol (2010) 184:5743-54. doi:10.4049/jimmunol.0903937
-
(2010)
J Immunol
, vol.184
, pp. 5743-5754
-
-
He, X.1
Mekasha, S.2
Mavrogiorgos, N.3
-
57
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
doi:10.1016/j.immuni.2009.02.006
-
Thomas PG, Dash P, Aldridge JR Jr, Ellebedy AH. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity (2009) 30(4):566-75. doi:10.1016/j.immuni.2009.02.006
-
(2009)
Immunity
, vol.30
, Issue.4
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge Jr., J.R.3
Ellebedy, A.H.4
-
58
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
doi:10.1016/j.immuni.2009.02.005
-
Allen IC, Scull MA, Moore CB, Holl EK. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity (2009) 30(4):556-65. doi:10.1016/j.immuni.2009.02.005
-
(2009)
Immunity
, vol.30
, Issue.4
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
Holl, E.K.4
-
59
-
-
77954958602
-
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase
-
doi:10.1371/journal.pone.0010008
-
Saïd-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS One (2010) 5:e10008. doi:10.1371/journal.pone.0010008
-
(2010)
PLoS One
, vol.5
-
-
Saïd-Sadier, N.1
Padilla, E.2
Langsley, G.3
Ojcius, D.M.4
-
60
-
-
84880255426
-
Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania
-
doi:10.1038/nm.3221
-
Lima-Junior DS, Costa DL, Carregaro V, Cunha LD, Silva ALN, Mineo TWP, et al. Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania. Nat Med (2013) 19:909-15. doi:10.1038/nm.3221
-
(2013)
Nat Med
, vol.19
, pp. 909-915
-
-
Lima-Junior, D.S.1
Costa, D.L.2
Carregaro, V.3
Cunha, L.D.4
Silva, A.L.N.5
Mineo, T.W.P.6
-
61
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
doi:10.1038/nature09663
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature (2010) 469:221-5. doi:10.1038/nature09663
-
(2010)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
62
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in Salmonella-infected macrophages
-
doi:10.1038/ni1346
-
Franchi L, Amer A, Body-Malapel M, Kanneganti T-D, Özören N, Jagirdar R, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in Salmonella-infected macrophages. Nat Immunol (2006) 7:576-82. doi:10.1038/ni1346
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.-D.4
Özören, N.5
Jagirdar, R.6
-
63
-
-
65449134828
-
Asc and Ipaf inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila
-
doi:10.1128/IAI.01382-08
-
Case CL, Shin S, Roy CR. Asc and Ipaf inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect Immun (2009) 77:1981-91. doi:10.1128/IAI.01382-08
-
(2009)
Infect Immun
, vol.77
, pp. 1981-1991
-
-
Case, C.L.1
Shin, S.2
Roy, C.R.3
-
64
-
-
45549092412
-
NAIP and Ipaf control Legionella pneumophila replication in human cells
-
Vinzing M, Eitel J, Lippmann J, Hocke AC, Zahlten J, Slevogt H, et al. NAIP and Ipaf control Legionella pneumophila replication in human cells. J Immunol (2008) 180:6808-15.
-
(2008)
J Immunol
, vol.180
, pp. 6808-6815
-
-
Vinzing, M.1
Eitel, J.2
Lippmann, J.3
Hocke, A.C.4
Zahlten, J.5
Slevogt, H.6
-
65
-
-
34548406570
-
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways
-
doi:10.1111/j.1462-5822.2007.00963.x
-
Coers J, Vance RE, Fontana MF, Dietrich WF. Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. Cell Microbiol (2007) 9:2344-57. doi:10.1111/j.1462-5822.2007.00963.x
-
(2007)
Cell Microbiol
, vol.9
, pp. 2344-2357
-
-
Coers, J.1
Vance, R.E.2
Fontana, M.F.3
Dietrich, W.F.4
-
66
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
doi:10.1038/nature02664
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature (2004) 430:213-8. doi:10.1038/nature02664
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
-
67
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
doi:10.1084/jem.20100257
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med (2010) 207:1745-55. doi:10.1084/jem.20100257
-
(2010)
J Exp Med
, vol.207
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
68
-
-
77649241461
-
From the cover: innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
doi:10.1073/pnas.0913087107
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, et al. From the cover: innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A (2010) 107:3076-80. doi:10.1073/pnas.0913087107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
-
69
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
doi:10.1371/journal.ppat.0030111
-
Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, Yoshikawa Y, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog (2007) 3:e111. doi:10.1371/journal.ppat.0030111
-
(2007)
PLoS Pathog
, vol.3
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
Ashida, H.4
Ogawa, M.5
Yoshikawa, Y.6
-
70
-
-
84875850500
-
Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia
-
doi:10.1172/JCI66142
-
Cohen TS, Prince AS. Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia. J Clin Invest (2013) 123:1630-7. doi:10.1172/JCI66142
-
(2013)
J Clin Invest
, vol.123
, pp. 1630-1637
-
-
Cohen, T.S.1
Prince, A.S.2
-
71
-
-
37549041954
-
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
-
doi:10.1084/jem.20071239
-
Sutterwala FS, Mijares LA, Li L, Ogura Y, Kazmierczak BI, Flavell RA. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 204:3235-45. doi:10.1084/jem.20071239
-
(2007)
J Exp Med
, vol.204
, pp. 3235-3245
-
-
Sutterwala, F.S.1
Mijares, L.A.2
Li, L.3
Ogura, Y.4
Kazmierczak, B.I.5
Flavell, R.A.6
-
72
-
-
36248940773
-
Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation
-
doi:10.1002/eji.200737532
-
Franchi L, Stoolman J, Kanneganti T-D, Verma A, Ramphal R, Nuñez G. Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation. Eur J Immunol (2007) 37:3030-9. doi:10.1002/eji.200737532
-
(2007)
Eur J Immunol
, vol.37
, pp. 3030-3039
-
-
Franchi, L.1
Stoolman, J.2
Kanneganti, T.-D.3
Verma, A.4
Ramphal, R.5
Nuñez, G.6
-
73
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
doi:10.1038/ni1305
-
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol (2006) 7:318-25. doi:10.1038/ni1305
-
(2006)
Nat Immunol
, vol.7
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
Vance, R.E.6
-
74
-
-
79953315378
-
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome
-
doi:10.1128/IAI.01187-10
-
Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer J-D, et al. Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infect Immun (2011) 79:1606-14. doi:10.1128/IAI.01187-10
-
(2011)
Infect Immun
, vol.79
, pp. 1606-1614
-
-
Lightfield, K.L.1
Persson, J.2
Trinidad, N.J.3
Brubaker, S.W.4
Kofoed, E.M.5
Sauer, J.-D.6
-
75
-
-
70449722759
-
T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii
-
doi:10.1038/ni.1816
-
Shaw MH, Reimer T, Sánchez-Valdepeñas C, Warner N, Kim Y-G, Fresno M, et al. T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii. Nat Immunol (2009) 10:1267-74. doi:10.1038/ni.1816
-
(2009)
Nat Immunol
, vol.10
, pp. 1267-1274
-
-
Shaw, M.H.1
Reimer, T.2
Sánchez-Valdepeñas, C.3
Warner, N.4
Kim, Y.-G.5
Fresno, M.6
-
76
-
-
82255194176
-
Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii
-
doi:10.1002/eji.201141876
-
Caetano BC, Biswas A, Lima DS, Benevides L, Mineo TWP, Horta CV, et al. Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii. Eur J Immunol (2011) 41:3627-31. doi:10.1002/eji.201141876
-
(2011)
Eur J Immunol
, vol.41
, pp. 3627-3631
-
-
Caetano, B.C.1
Biswas, A.2
Lima, D.S.3
Benevides, L.4
Mineo, T.W.P.5
Horta, C.V.6
-
77
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
doi:10.1038/35079107
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature (2001) 411:599-603. doi:10.1038/35079107
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
-
78
-
-
22244465576
-
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition
-
doi:10.1083/jcb.200502153
-
Barnich N, Aguirre JE, Reinecker H-C, Xavier R, Podolsky DK. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition. J Cell Biol (2005) 170:21-6. doi:10.1083/jcb.200502153
-
(2005)
J Cell Biol
, vol.170
, pp. 21-26
-
-
Barnich, N.1
Aguirre, J.E.2
Reinecker, H.-C.3
Xavier, R.4
Podolsky, D.K.5
-
79
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
doi:10.1038/nri3452
-
Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol (2013) 13:397-411. doi:10.1038/nri3452
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
80
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
-
doi:10.1038/ni.1935
-
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes. Nat Immunol (2010) 11:897-904. doi:10.1038/ni.1935
-
(2010)
Nat Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
-
81
-
-
84880280093
-
Crystal structure of NLRC4 reveals its autoinhibition mechanism
-
doi:10.1126/science.1236381
-
Hu Z, Yan C, Liu P, Huang Z, Ma R, Zhang C, et al. Crystal structure of NLRC4 reveals its autoinhibition mechanism. Science (2013) 341:172-5. doi:10.1126/science.1236381
-
(2013)
Science
, vol.341
, pp. 172-175
-
-
Hu, Z.1
Yan, C.2
Liu, P.3
Huang, Z.4
Ma, R.5
Zhang, C.6
-
82
-
-
84883441989
-
Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and-independent macrophage responses
-
doi:10.1073/pnas.1305316110
-
Lage SL, Buzzo CL, Amaral EP, Matteucci KC, Massis LM, Icimoto MY, et al. Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and-independent macrophage responses. Proc Natl Acad Sci U S A (2013) 110:E3321-30. doi:10.1073/pnas.1305316110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
-
-
Lage, S.L.1
Buzzo, C.L.2
Amaral, E.P.3
Matteucci, K.C.4
Massis, L.M.5
Icimoto, M.Y.6
-
84
-
-
70350365362
-
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
-
doi:10.1242/jcs.051193
-
Arnoult D, Soares F, Tattoli I, Castanier C, Philpott DJ, Girardin SE. An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix. J Cell Sci (2009) 122:3161-8. doi:10.1242/jcs.051193
-
(2009)
J Cell Sci
, vol.122
, pp. 3161-3168
-
-
Arnoult, D.1
Soares, F.2
Tattoli, I.3
Castanier, C.4
Philpott, D.J.5
Girardin, S.E.6
-
85
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
doi:10.1038/nature06501
-
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature (2008) 451:573-7. doi:10.1038/nature06501
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
Bergstralh, D.T.2
Duncan, J.A.3
Lei, Y.4
Morrison, T.E.5
Zimmermann, A.G.6
-
86
-
-
84862301902
-
Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program
-
doi:10.1016/j.chom.2012.04.012
-
Tattoli I, Sorbara MT, Vuckovic D, Ling A, Soares F, Carneiro LAM, et al. Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host Microbe (2012) 11:563-75. doi:10.1016/j.chom.2012.04.012
-
(2012)
Cell Host Microbe
, vol.11
, pp. 563-575
-
-
Tattoli, I.1
Sorbara, M.T.2
Vuckovic, D.3
Ling, A.4
Soares, F.5
Carneiro, L.A.M.6
-
87
-
-
84866386287
-
Structural and functional analysis of the NLRP4 pyrin domain
-
doi:10.1021/bi3007059
-
Eibl C, Grigoriu S, Hessenberger M, Wenger J, Puehringer S, Pinheiro AS, et al. Structural and functional analysis of the NLRP4 pyrin domain. Biochemistry (2012) 51:7330-41. doi:10.1021/bi3007059
-
(2012)
Biochemistry
, vol.51
, pp. 7330-7341
-
-
Eibl, C.1
Grigoriu, S.2
Hessenberger, M.3
Wenger, J.4
Puehringer, S.5
Pinheiro, A.S.6
-
88
-
-
84862815491
-
NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4
-
doi:10.1038/ni.2239
-
Cui J, Li Y, Zhu L, Liu D, Songyang Z, Wang HY, et al. NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. Nat Immunol (2012) 13:387-95. doi:10.1038/ni.2239
-
(2012)
Nat Immunol
, vol.13
, pp. 387-395
-
-
Cui, J.1
Li, Y.2
Zhu, L.3
Liu, D.4
Songyang, Z.5
Wang, H.Y.6
-
89
-
-
35448981935
-
Autophagy: from phenomenology to molecular understanding in less than a decade
-
doi:10.1038/nrm2245
-
Klionsky DJ. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol (2007) 8:931-7. doi:10.1038/nrm2245
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 931-937
-
-
Klionsky, D.J.1
-
90
-
-
77956404377
-
Eaten alive: a history of macroautophagy
-
doi:10.1038/ncb0910-814
-
Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol (2010) 12:814-22. doi:10.1038/ncb0910-814
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
91
-
-
84877628647
-
Autophagy in human health and disease
-
doi:10.1056/NEJMra1205406
-
Choi AMK, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med (2013) 368:651-62. doi:10.1056/NEJMra1205406
-
(2013)
N Engl J Med
, vol.368
, pp. 651-662
-
-
Choi, A.M.K.1
Ryter, S.W.2
Levine, B.3
-
92
-
-
69949110579
-
Autophagy as an emerging dimension to adaptive and innate immunity
-
doi:10.1016/j.smim.2009.05.004
-
Hussey S, Travassos LH, Jones NL. Autophagy as an emerging dimension to adaptive and innate immunity. Semin Immunol (2009) 21:233-41. doi:10.1016/j.smim.2009.05.004
-
(2009)
Semin Immunol
, vol.21
, pp. 233-241
-
-
Hussey, S.1
Travassos, L.H.2
Jones, N.L.3
-
93
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
doi:10.1038/nature06639
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature (2008) 451:1069-75. doi:10.1038/nature06639
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
94
-
-
84855286487
-
Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites
-
doi:10.1371/journal.ppat.1002416
-
Besteiro S, Brooks CF, Striepen B, Dubremetz JF. Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites. PLoS Pathog (2011) 7(12):e1002416. doi:10.1371/journal.ppat.1002416
-
(2011)
PLoS Pathog
, vol.7
, Issue.12
-
-
Besteiro, S.1
Brooks, C.F.2
Striepen, B.3
Dubremetz, J.F.4
-
95
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
doi:10.4161/auto.19926
-
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 8:445-544. doi:10.4161/auto.19926
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
-
96
-
-
84871581862
-
Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis
-
doi:10.1016/j.cell.2012.11.028
-
Ragusa MJ, Stanley RE, Hurley JH. Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell (2012) 151:1501-12. doi:10.1016/j.cell.2012.11.028
-
(2012)
Cell
, vol.151
, pp. 1501-1512
-
-
Ragusa, M.J.1
Stanley, R.E.2
Hurley, J.H.3
-
97
-
-
82855170846
-
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction
-
doi:10.4161/auto.7.12.18027
-
Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, et al. Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction. Autophagy (2011) 7:1423-33. doi:10.4161/auto.7.12.18027
-
(2011)
Autophagy
, vol.7
, pp. 1423-1433
-
-
Alers, S.1
Löffler, A.S.2
Paasch, F.3
Dieterle, A.M.4
Keppeler, H.5
Lauber, K.6
-
98
-
-
84883740868
-
Uba1 functions in Atg7-and Atg3-independent autophagy
-
doi:10.1038/ncb2804
-
Chang T-K, Shravage BV, Hayes SD, Powers CM, Simin RT, Wade Harper J, et al. Uba1 functions in Atg7-and Atg3-independent autophagy. Nat Cell Biol (2013) 15:1067-78. doi:10.1038/ncb2804
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1067-1078
-
-
Chang, T.-K.1
Shravage, B.V.2
Hayes, S.D.3
Powers, C.M.4
Simin, R.T.5
Wade Harper, J.6
-
99
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
doi:10.1038/nature08455
-
Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T, et al. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature (2009) 461:654-8. doi:10.1038/nature08455
-
(2009)
Nature
, vol.461
, pp. 654-658
-
-
Nishida, Y.1
Arakawa, S.2
Fujitani, K.3
Yamaguchi, H.4
Mizuta, T.5
Kanaseki, T.6
-
100
-
-
0027311858
-
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
-
doi:10.1016/0092-8674(93)90144-F
-
Kunz J, Henriquez R, Schneider U, Deuter-Reinhard M, Movva NR, Hall MN. Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell (1993) 73:585-96. doi:10.1016/0092-8674(93)90144-F
-
(1993)
Cell
, vol.73
, pp. 585-596
-
-
Kunz, J.1
Henriquez, R.2
Schneider, U.3
Deuter-Reinhard, M.4
Movva, N.R.5
Hall, M.N.6
-
101
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
doi:10.1126/science.8385367
-
Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science (1993) 260:88-91. doi:10.1126/science.8385367
-
(1993)
Science
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
102
-
-
0029831167
-
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
-
Brunn GJ, Williams J, Sabers C, Wiederrecht G, Lawrence JC, Abraham RT. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J (1996) 15:5256-67.
-
(1996)
EMBO J
, vol.15
, pp. 5256-5267
-
-
Brunn, G.J.1
Williams, J.2
Sabers, C.3
Wiederrecht, G.4
Lawrence, J.C.5
Abraham, R.T.6
-
103
-
-
2342472012
-
Towards an understanding of isoform specificity in phosphoinositide 3-kinase signalling in lymphocytes
-
doi:10.1042/BST0320315
-
Fruman DA. Towards an understanding of isoform specificity in phosphoinositide 3-kinase signalling in lymphocytes. Biochem Soc Trans (2004) 32:315-9. doi:10.1042/BST0320315
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 315-319
-
-
Fruman, D.A.1
-
104
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, et al. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J (1996) 15:6541-51.
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
-
106
-
-
4043171462
-
Upstream and downstream of mTOR
-
doi:10.1101/gad.1212704
-
Hay N. Upstream and downstream of mTOR. Genes Dev (2004) 18:1926-45. doi:10.1101/gad.1212704
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
-
107
-
-
17144427728
-
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
-
doi:10.1158/0008-5472.CAN-04-3640
-
Takeuchi H, Kondo Y, Fujiwara K, Kanzawa T, Aoki H, Mills GB, et al. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res (2005) 65:3336-46. doi:10.1158/0008-5472.CAN-04-3640
-
(2005)
Cancer Res
, vol.65
, pp. 3336-3346
-
-
Takeuchi, H.1
Kondo, Y.2
Fujiwara, K.3
Kanzawa, T.4
Aoki, H.5
Mills, G.B.6
-
108
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
doi:10.1091/mbc.E08-12-1249
-
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell (2009) 20:1992-2003. doi:10.1091/mbc.E08-12-1249
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
-
109
-
-
84866426794
-
Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy
-
doi:10.1038/emboj.2012.225
-
Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, et al. Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy. EMBO J (2012) 31:3691-703. doi:10.1038/emboj.2012.225
-
(2012)
EMBO J
, vol.31
, pp. 3691-3703
-
-
Kraft, C.1
Kijanska, M.2
Kalie, E.3
Siergiejuk, E.4
Lee, S.S.5
Semplicio, G.6
-
110
-
-
84881553725
-
K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells
-
doi:10.1016/j.molcel.2013.06.020
-
Linares JF, Duran A, Yajima T, Pasparakis M, Moscat J, Diaz-Meco MT. K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells. Mol Cell (2013) 51:283-96. doi:10.1016/j.molcel.2013.06.020
-
(2013)
Mol Cell
, vol.51
, pp. 283-296
-
-
Linares, J.F.1
Duran, A.2
Yajima, T.3
Pasparakis, M.4
Moscat, J.5
Diaz-Meco, M.T.6
-
111
-
-
33645078650
-
Regulation of membrane traffic by phosphoinositide 3-kinases
-
doi:10.1242/jcs.02855
-
Lindmo K. Regulation of membrane traffic by phosphoinositide 3-kinases. J Cell Sci (2006) 119:605-14. doi:10.1242/jcs.02855
-
(2006)
J Cell Sci
, vol.119
, pp. 605-614
-
-
Lindmo, K.1
-
112
-
-
0033978633
-
Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
-
doi:10.1074/jbc.275.2.992
-
Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem (2000) 275:992-8. doi:10.1074/jbc.275.2.992
-
(2000)
J Biol Chem
, vol.275
, pp. 992-998
-
-
Petiot, A.1
Ogier-Denis, E.2
Blommaart, E.F.3
Meijer, A.J.4
Codogno, P.5
-
113
-
-
84866158316
-
Phosphatidylinositol-3-phosphate clearance plays a key role in autophagosome completion
-
doi:10.1016/j.cub.2012.06.029
-
Cebollero E, van der Vaart A, Zhao M, Rieter E, Klionsky DJ, Helms JB, et al. Phosphatidylinositol-3-phosphate clearance plays a key role in autophagosome completion. Curr Biol (2012) 22:1545-53. doi:10.1016/j.cub.2012.06.029
-
(2012)
Curr Biol
, vol.22
, pp. 1545-1553
-
-
Cebollero, E.1
van der Vaart, A.2
Zhao, M.3
Rieter, E.4
Klionsky, D.J.5
Helms, J.B.6
-
114
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
doi:10.1038/ncb2788
-
Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol (2013) 15:713-20. doi:10.1038/ncb2788
-
(2013)
Nat Cell Biol
, vol.15
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
115
-
-
84858016996
-
Autophagy and bacterial infectious diseases
-
doi:10.3858/emm.2012.44.2.032
-
Yuk JM, Yoshimori T, Jo E-K. Autophagy and bacterial infectious diseases. Exp Mol Med (2012) 44:99-108. doi:10.3858/emm.2012.44.2.032
-
(2012)
Exp Mol Med
, vol.44
, pp. 99-108
-
-
Yuk, J.M.1
Yoshimori, T.2
Jo, E.-K.3
-
116
-
-
8344247016
-
Autophagy defends cells against invading group A Streptococcus
-
doi:10.1126/science.1103966
-
Nakagawa I, Amano A, Mizushima N, Yamamoto A, Yamaguchi H, Kamimoto T, et al. Autophagy defends cells against invading group A Streptococcus. Science (2004) 306:1037-40. doi:10.1126/science.1103966
-
(2004)
Science
, vol.306
, pp. 1037-1040
-
-
Nakagawa, I.1
Amano, A.2
Mizushima, N.3
Yamamoto, A.4
Yamaguchi, H.5
Kamimoto, T.6
-
117
-
-
77958107375
-
Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB
-
doi:10.1016/j.micinf.2010.06.006
-
Kayath CA, Hussey S, El Hajjami N, Nagra K, Philpott D, Allaoui A. Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB. Microbes Infect (2010) 12:956-66. doi:10.1016/j.micinf.2010.06.006
-
(2010)
Microbes Infect
, vol.12
, pp. 956-966
-
-
Kayath, C.A.1
Hussey, S.2
El Hajjami, N.3
Nagra, K.4
Philpott, D.5
Allaoui, A.6
-
118
-
-
13244256806
-
Escape of intracellular Shigella from autophagy
-
doi:10.1126/science.1106036
-
Ogawa M, Yoshimori T, Suzuki T, Sagara H, Mizushima N, Sasakawa C. Escape of intracellular Shigella from autophagy. Science (2005) 307:727-31. doi:10.1126/science.1106036
-
(2005)
Science
, vol.307
, pp. 727-731
-
-
Ogawa, M.1
Yoshimori, T.2
Suzuki, T.3
Sagara, H.4
Mizushima, N.5
Sasakawa, C.6
-
119
-
-
68349143052
-
Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy
-
doi:10.1016/j.chom.2009.07.005
-
Dupont N, Lacas-Gervais S, Bertout J, Paz I, Freche B, Van Nhieu GT, et al. Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe (2009) 6:137-49. doi:10.1016/j.chom.2009.07.005
-
(2009)
Cell Host Microbe
, vol.6
, pp. 137-149
-
-
Dupont, N.1
Lacas-Gervais, S.2
Bertout, J.3
Paz, I.4
Freche, B.5
Van Nhieu, G.T.6
-
120
-
-
50249111985
-
Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines
-
Cullinane M, Gong L, Li X, Lazar-Adler N, Tra T, Wolvetang E, et al. Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines. Autophagy (2008) 4:744-53.
-
(2008)
Autophagy
, vol.4
, pp. 744-753
-
-
Cullinane, M.1
Gong, L.2
Li, X.3
Lazar-Adler, N.4
Tra, T.5
Wolvetang, E.6
-
121
-
-
38349110486
-
Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles
-
doi:10.1038/nature06479
-
Birmingham CL, Canadien V, Kaniuk NA, Steinberg BE, Higgins DE, Brumell JH. Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles. Nature (2008) 451:350-4. doi:10.1038/nature06479
-
(2008)
Nature
, vol.451
, pp. 350-354
-
-
Birmingham, C.L.1
Canadien, V.2
Kaniuk, N.A.3
Steinberg, B.E.4
Higgins, D.E.5
Brumell, J.H.6
-
122
-
-
33744958258
-
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole
-
doi:10.1074/jbc.M509157200
-
Birmingham CL. Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. J Biol Chem (2006) 281:11374-83. doi:10.1074/jbc.M509157200
-
(2006)
J Biol Chem
, vol.281
, pp. 11374-11383
-
-
Birmingham, C.L.1
-
123
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
doi:10.1016/j.cell.2004.11.038
-
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell (2004) 119:1-14. doi:10.1016/j.cell.2004.11.038
-
(2004)
Cell
, vol.119
, pp. 1-14
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
Taylor, G.A.4
Colombo, M.I.5
Deretic, V.6
-
124
-
-
33947715151
-
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein
-
doi:10.1016/j.chom.2006.12.001
-
Orvedahl A, Alexander D, Tallóczy Z, Sun Q, Wei Y, Zhang W, et al. HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe (2007) 1:23-35. doi:10.1016/j.chom.2006.12.001
-
(2007)
Cell Host Microbe
, vol.1
, pp. 23-35
-
-
Orvedahl, A.1
Alexander, D.2
Tallóczy, Z.3
Sun, Q.4
Wei, Y.5
Zhang, W.6
-
125
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
doi:10.1126/science.1136880
-
Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science (2007) 315:1398-401. doi:10.1126/science.1136880
-
(2007)
Science
, vol.315
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
126
-
-
34447643958
-
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
-
doi:10.1016/j.immuni.2007.05.022
-
Xu Y, Jagannath C, Liu X-D, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity (2007) 27:135-44. doi:10.1016/j.immuni.2007.05.022
-
(2007)
Immunity
, vol.27
, pp. 135-144
-
-
Xu, Y.1
Jagannath, C.2
Liu, X.-D.3
Sharafkhaneh, A.4
Kolodziejska, K.E.5
Eissa, N.T.6
-
127
-
-
41949101594
-
Toll-like receptors control autophagy
-
doi:10.1038/emboj.2008.31
-
Delgado MA, Elmaoued RA, Davis AS, Kyei G, Deretic V. Toll-like receptors control autophagy. EMBO J (2008) 27:1110-21. doi:10.1038/emboj.2008.31
-
(2008)
EMBO J
, vol.27
, pp. 1110-1121
-
-
Delgado, M.A.1
Elmaoued, R.A.2
Davis, A.S.3
Kyei, G.4
Deretic, V.5
-
128
-
-
57749100267
-
MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages
-
doi:10.1074/jbc.M804478200
-
Shi C-S, Kehrl JH. MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J Biol Chem (2008) 283:33175-82. doi:10.1074/jbc.M804478200
-
(2008)
J Biol Chem
, vol.283
, pp. 33175-33182
-
-
Shi, C.-S.1
Kehrl, J.H.2
-
129
-
-
58149352480
-
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells
-
doi:10.1002/eji.200838761
-
Schmitz F, Heit A, Dreher S, Eisenächer K, Mages J, Haas T, et al. Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells. Eur J Immunol (2008) 38:2981-92. doi:10.1002/eji.200838761
-
(2008)
Eur J Immunol
, vol.38
, pp. 2981-2992
-
-
Schmitz, F.1
Heit, A.2
Dreher, S.3
Eisenächer, K.4
Mages, J.5
Haas, T.6
-
130
-
-
47849094901
-
Autophagic control of listeria through intracellular innate immune recognition in Drosophila
-
doi:10.1038/ni.1634
-
Yano T, Mita S, Ohmori H, Oshima Y, Fujimoto Y, Ueda R, et al. Autophagic control of listeria through intracellular innate immune recognition in Drosophila. Nat Immunol (2008) 9:908-16. doi:10.1038/ni.1634
-
(2008)
Nat Immunol
, vol.9
, pp. 908-916
-
-
Yano, T.1
Mita, S.2
Ohmori, H.3
Oshima, Y.4
Fujimoto, Y.5
Ueda, R.6
-
131
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
doi:10.1038/nm.2069
-
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med (2009) 16:90-7. doi:10.1038/nm.2069
-
(2009)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
Danis, B.4
Pichulik, T.5
Allan, P.6
-
132
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
doi:10.1038/ni.1823
-
Travassos LH, Carneiro LAM, Ramjeet M, Hussey S, Kim Y-G, Magalhaes JG, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol (2010) 11:55-62. doi:10.1038/ni.1823
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.M.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.-G.5
Magalhaes, J.G.6
-
133
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
doi:10.1038/ng2032
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 39:596-604. doi:10.1038/ng2032
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
134
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
doi:10.1371/journal.pone.0003391
-
Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS One (2008) 3:e3391. doi:10.1371/journal.pone.0003391
-
(2008)
PLoS One
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
Daly, M.J.4
Xavier, R.J.5
-
135
-
-
79959655886
-
NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease
-
doi:10.3748/wjg.v17.i23.2829
-
Glubb DM, Gearry RB, Barclay ML, Roberts RL, Pearson J, Keenan JI, et al. NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease. World J Gastroenterol (2011) 17:2829-37. doi:10.3748/wjg.v17.i23.2829
-
(2011)
World J Gastroenterol
, vol.17
, pp. 2829-2837
-
-
Glubb, D.M.1
Gearry, R.B.2
Barclay, M.L.3
Roberts, R.L.4
Pearson, J.5
Keenan, J.I.6
-
136
-
-
80052389178
-
ATG16L1 polymorphisms are associated with NOD2-induced hyperinflammation
-
doi:10.4161/auto.7.9.15867
-
Plantinga TS, Joosten LA, Netea MG. ATG16L1 polymorphisms are associated with NOD2-induced hyperinflammation. Autophagy (2011) 7:1074-5. doi:10.4161/auto.7.9.15867
-
(2011)
Autophagy
, vol.7
, pp. 1074-1075
-
-
Plantinga, T.S.1
Joosten, L.A.2
Netea, M.G.3
-
137
-
-
80053625777
-
Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response
-
doi:10.1111/j.1365-2567.2011.03494.x
-
Kleinnijenhuis J, Oosting M, Plantinga TS, van der Meer JWM, Joosten LAB, Crevel RV, et al. Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response. Immunology (2011) 134:341-8. doi:10.1111/j.1365-2567.2011.03494.x
-
(2011)
Immunology
, vol.134
, pp. 341-348
-
-
Kleinnijenhuis, J.1
Oosting, M.2
Plantinga, T.S.3
van der Meer, J.W.M.4
Joosten, L.A.B.5
Crevel, R.V.6
-
138
-
-
84874596968
-
Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection
-
doi:10.1128/mBio.00620-12
-
Byrne BG, Dubuisson JF, Joshi AD, Persson JJ, Swanson MS. Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection. MBio (2012) 4:e620-612. doi:10.1128/mBio.00620-12
-
(2012)
MBio
, vol.4
-
-
Byrne, B.G.1
Dubuisson, J.F.2
Joshi, A.D.3
Persson, J.J.4
Swanson, M.S.5
-
139
-
-
84863005844
-
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates Type I interferon and autophagy
-
doi:10.1016/j.immuni.2012.03.025
-
Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates Type I interferon and autophagy. Immunity (2012) 36:933-46. doi:10.1016/j.immuni.2012.03.025
-
(2012)
Immunity
, vol.36
, pp. 933-946
-
-
Lei, Y.1
Wen, H.2
Yu, Y.3
Taxman, D.J.4
Zhang, L.5
Widman, D.G.6
-
140
-
-
64049114864
-
Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus
-
doi:10.1016/j.immuni.2009.02.009
-
Shelly S, Lukinova N, Bambina S, Berman A, Cherry S. Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus. Immunity (2009) 30:588-98. doi:10.1016/j.immuni.2009.02.009
-
(2009)
Immunity
, vol.30
, pp. 588-598
-
-
Shelly, S.1
Lukinova, N.2
Bambina, S.3
Berman, A.4
Cherry, S.5
-
141
-
-
84880299261
-
NLRX1 does not inhibit MAVS-dependent antiviral signalling
-
doi:10.1177/1753425912467383
-
Soares F, Tattoli I, Wortzman ME, Arnoult D, Philpott DJ, Girardin SE. NLRX1 does not inhibit MAVS-dependent antiviral signalling. Innate Immun (2012) 19(4):438-48. doi:10.1177/1753425912467383
-
(2012)
Innate Immun
, vol.19
, Issue.4
, pp. 438-448
-
-
Soares, F.1
Tattoli, I.2
Wortzman, M.E.3
Arnoult, D.4
Philpott, D.J.5
Girardin, S.E.6
-
142
-
-
79960205819
-
NLRX1/NOD5 deficiency does not affect MAVS signalling
-
doi:10.1038/cdd.2011.64
-
Rebsamen M, Vazquez J, Tardivel A, Guarda G, Curran J, Tschopp J. NLRX1/NOD5 deficiency does not affect MAVS signalling. Cell Death Differ (2011) 18:1387-1387. doi:10.1038/cdd.2011.64
-
(2011)
Cell Death Differ
, vol.18
, pp. 1387-1387
-
-
Rebsamen, M.1
Vazquez, J.2
Tardivel, A.3
Guarda, G.4
Curran, J.5
Tschopp, J.6
-
143
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling
-
doi:10.1016/j.immuni.2012.03.012
-
Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity (2012) 36:742-54. doi:10.1016/j.immuni.2012.03.012
-
(2012)
Immunity
, vol.36
, pp. 742-754
-
-
Allen, I.C.1
Wilson, J.E.2
Schneider, M.3
Lich, J.D.4
Roberts, R.A.5
Arthur, J.C.6
-
144
-
-
79251588741
-
NLRP4 negatively regulates autophagic processes through an association with Beclin1
-
doi:10.4049/jimmunol.1001654
-
Jounai N, Kobiyama K, Shiina M, Ogata K, Ishii KJ, Takeshita F. NLRP4 negatively regulates autophagic processes through an association with Beclin1. J Immunol (2011) 186:1646-55. doi:10.4049/jimmunol.1001654
-
(2011)
J Immunol
, vol.186
, pp. 1646-1655
-
-
Jounai, N.1
Kobiyama, K.2
Shiina, M.3
Ogata, K.4
Ishii, K.J.5
Takeshita, F.6
-
145
-
-
78751672975
-
Autophagy in immunity and inflammation
-
doi:10.1038/nature09782
-
Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature (2011) 469:323-35. doi:10.1038/nature09782
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
146
-
-
35348921764
-
The Atg5 Atg12 conjugate associates with innate antiviral immune responses
-
doi:10.1073/pnas.0704014104
-
Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, et al. The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proc Natl Acad Sci U S A (2007) 104:14050-5. doi:10.1073/pnas.0704014104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14050-14055
-
-
Jounai, N.1
Takeshita, F.2
Kobiyama, K.3
Sawano, A.4
Miyawaki, A.5
Xin, K.Q.6
-
147
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
doi:10.1073/pnas.0807694106
-
Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci U S A (2009) 106:2770-5. doi:10.1073/pnas.0807694106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
148
-
-
84876685141
-
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
-
doi:10.1038/ni.2563
-
Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, et al. Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol (2013) 14:480-8. doi:10.1038/ni.2563
-
(2013)
Nat Immunol
, vol.14
, pp. 480-488
-
-
Lupfer, C.1
Thomas, P.G.2
Anand, P.K.3
Vogel, P.4
Milasta, S.5
Martinez, J.6
-
149
-
-
79953176280
-
Autophagy controls IL-1 secretion by targeting pro-IL-1 for degradation
-
doi:10.1074/jbc.M110.202911
-
Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, et al. Autophagy controls IL-1 secretion by targeting pro-IL-1 for degradation. J Biol Chem (2011) 286:9587-97. doi:10.1074/jbc.M110.202911
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
Zeng, S.G.4
O'Shea, A.5
Sharp, F.A.6
-
150
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
-
doi:10.1038/nature07383
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang B-G, Satoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production. Nature (2008) 456:264-8. doi:10.1038/nature07383
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.-G.5
Satoh, T.6
-
151
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
-
doi:10.1038/ni.2215
-
Shi C-S, Shenderov K, Huang N-N, Kabat J, Abu-Asab M, Fitzgerald KA, et al. Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol (2012) 13:255-63. doi:10.1038/ni.2215
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.-S.1
Shenderov, K.2
Huang, N.-N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
-
152
-
-
79960542894
-
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
doi:10.4049/jimmunol.1100613
-
Bauernfeind F, Bartok E, Rieger A, Franchi L, Nuñez G, Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol (2011) 187:613-7. doi:10.4049/jimmunol.1100613
-
(2011)
J Immunol
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nuñez, G.5
Hornung, V.6
-
153
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
doi:10.1126/science.1156995
-
Dostert C, Pétrilli V, van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 320:674-7. doi:10.1126/science.1156995
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Pétrilli, V.2
van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
154
-
-
77956574503
-
NOX-free inflammasome activation
-
doi:10.1182/blood-2010-06-287342
-
Latz E. NOX-free inflammasome activation. Blood (2010) 116:1393-4. doi:10.1182/blood-2010-06-287342
-
(2010)
Blood
, vol.116
, pp. 1393-1394
-
-
Latz, E.1
-
155
-
-
77956601381
-
Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease
-
doi:10.1182/blood-2010-01-264218
-
Meissner F, Seger RA, Moshous D, Fischer A, Reichenbach J, Zychlinsky A. Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease. Blood (2010) 116:1570-3. doi:10.1182/blood-2010-01-264218
-
(2010)
Blood
, vol.116
, pp. 1570-1573
-
-
Meissner, F.1
Seger, R.A.2
Moshous, D.3
Fischer, A.4
Reichenbach, J.5
Zychlinsky, A.6
-
156
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
doi:10.1146/annurev-immunol-031210-101405
-
Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol (2011) 29:707-35. doi:10.1146/annurev-immunol-031210-101405
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
157
-
-
82455210868
-
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
-
doi:10.1038/emboj.2011.398
-
Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. EMBO J (2011) 30:4701-11. doi:10.1038/emboj.2011.398
-
(2011)
EMBO J
, vol.30
, pp. 4701-4711
-
-
Dupont, N.1
Jiang, S.2
Pilli, M.3
Ornatowski, W.4
Bhattacharya, D.5
Deretic, V.6
-
158
-
-
84867770402
-
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
-
doi:10.1074/jbc.M112.407130
-
Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, Alnemri ES. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem (2012) 287:36617-22. doi:10.1074/jbc.M112.407130
-
(2012)
J Biol Chem
, vol.287
, pp. 36617-36622
-
-
Juliana, C.1
Fernandes-Alnemri, T.2
Kang, S.3
Farias, A.4
Qin, F.5
Alnemri, E.S.6
-
159
-
-
0142180157
-
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
-
doi:10.1074/jbc.M307198200
-
Girardin SE, Travassos LH, Hervé M, Blanot D, Boneca IG, Philpott DJ, et al. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem (2003) 278:41702-8. doi:10.1074/jbc.M307198200
-
(2003)
J Biol Chem
, vol.278
, pp. 41702-41708
-
-
Girardin, S.E.1
Travassos, L.H.2
Hervé, M.3
Blanot, D.4
Boneca, I.G.5
Philpott, D.J.6
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