Application of Short- and Long-Term Hepatocyte Cultures to Predict Toxicities

Hepatotoxicity: From Genomics to in vitro and in vivo Models

Volumn , Issue , 2008, Pages 139-174

  Tuschl, Gregor ^a   Hrach, Jens ^a   Hewitt, Philip G ^a   Mueller, Stefan O ^a  

^a MERCK KGAA   (Germany)

Author keywords

Cell matrix interactions; Chemical induced hepatotoxicity; Drug metabolism and biotransformation; High content screening (HCS); Hypersensitivity and skin reactions; Mitochondrial function inhibition; Pathophysiological mechanisms; Standard cytotoxicity assays; Sub lethal doses; Transgenic cells and sub cellular fractions

Indexed keywords

EID: 84889497874     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470516751.ch7     Document Type: Chapter

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