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Volumn 34, Issue 4, 2006, Pages 556-562

Characterization of transport protein expression in multidrug resistance-associated protein (MRP) 2-deficient rats

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; BILE SALT; BREAST CANCER RESISTANCE PROTEIN; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 1A1; ORGANIC ANION TRANSPORTER 1A4; PROTEINASE INHIBITOR; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

EID: 33645104770     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.005793     Document Type: Article
Times cited : (109)

References (46)
  • 1
    • 0034802573 scopus 로고    scopus 로고
    • Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver
    • Akita H, Suzuki H, and Sugiyama Y (2001) Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver. Pharm Res (NY) 18:1119-1125.
    • (2001) Pharm Res (NY) , vol.18 , pp. 1119-1125
    • Akita, H.1    Suzuki, H.2    Sugiyama, Y.3
  • 3
    • 2542440464 scopus 로고    scopus 로고
    • Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice
    • Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, et al. (2004) Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J Biol Chem 279:22250-22257.
    • (2004) J Biol Chem , vol.279 , pp. 22250-22257
    • Assem, M.1    Schuetz, E.G.2    Leggas, M.3    Sun, D.4    Yasuda, K.5    Reid, G.6    Zelcer, N.7    Adachi, M.8    Strom, S.9    Evans, R.M.10
  • 6
    • 0346728729 scopus 로고    scopus 로고
    • The ABCs of drug transport in intestine and liver: Efflux proteins limiting drug absorption and bioavailability
    • Chan LMS, Lowes S, and Hirst BH (2004) The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability. Eur J Pharm Sci 21:25-51.
    • (2004) Eur J Pharm Sci , vol.21 , pp. 25-51
    • Chan, L.M.S.1    Lowes, S.2    Hirst, B.H.3
  • 7
    • 3542995726 scopus 로고    scopus 로고
    • The complexities of hepatic drug transport: Current knowledge and emerging concepts
    • Chandra P and Brouwer KLR (2004) The complexities of hepatic drug transport: Current knowledge and emerging concepts. Pharm Res (NY) 21:719-735.
    • (2004) Pharm Res (NY) , vol.21 , pp. 719-735
    • Chandra, P.1    Brouwer, K.L.R.2
  • 9
    • 1642422386 scopus 로고    scopus 로고
    • Rat multidrug resistance protein 4 (Mrp4, Abcc4): Molecular cloning, organ distribution, postnatal renal expression and chemical inducibility
    • Chen C and Klaassen CD (2004) Rat multidrug resistance protein 4 (Mrp4, Abcc4): molecular cloning, organ distribution, postnatal renal expression and chemical inducibility. Biochem Biophys Res Commun 317:46-53.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 46-53
    • Chen, C.1    Klaassen, C.D.2
  • 11
    • 0038650987 scopus 로고    scopus 로고
    • Nuclear receptor, pregnane X receptor, is required for induction of UDP-glucuronosyltransferases in mouse liver by pregnenolone-16 alpha-carbonitrile
    • Chen C, Staudinger JL, and Klaassen CD (2003b) Nuclear receptor, pregnane X receptor, is required for induction of UDP-glucuronosyltransferases in mouse liver by pregnenolone-16 alpha-carbonitrile. Drug Metab Dispos 31:908-915.
    • (2003) Drug Metab Dispos , vol.31 , pp. 908-915
    • Chen, C.1    Staudinger, J.L.2    Klaassen, C.D.3
  • 12
    • 0035034532 scopus 로고    scopus 로고
    • Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats
    • Dietrich CG, De Waart DR, Ottenhoff R, Schoots IG, and Oude Elferink RP (2001) Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats. Mol Pharmacol 59:974-980.
    • (2001) Mol Pharmacol , vol.59 , pp. 974-980
    • Dietrich, C.G.1    De Waart, D.R.2    Ottenhoff, R.3    Schoots, I.G.4    Oude Elferink, R.P.5
  • 13
    • 0000552161 scopus 로고
    • Chronic idiopathic jaundice with unidentified pigment in liver cells
    • Dubin IN and Johnson FB (1954) Chronic idiopathic jaundice with unidentified pigment in liver cells. Medicine 33:155-179.
    • (1954) Medicine , vol.33 , pp. 155-179
    • Dubin, I.N.1    Johnson, F.B.2
  • 14
    • 0032859340 scopus 로고    scopus 로고
    • Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain
    • Gao B, Stieger B, Noé B, Fritschy JM, and Meier PJ (1999) Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain. J Histochem Cytochem 47:1255-1264.
    • (1999) J Histochem Cytochem , vol.47 , pp. 1255-1264
    • Gao, B.1    Stieger, B.2    Noé, B.3    Fritschy, J.M.4    Meier, P.J.5
  • 15
    • 0242665373 scopus 로고    scopus 로고
    • Complementary roles of farnesoid X receptor, pregnane X receptor and constitutive androstane receptor in protection against bile acid toxicity
    • Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, Kliewer SA, Gonzalez FJ, and Sinal CJ (2003) Complementary roles of farnesoid X receptor, pregnane X receptor and constitutive androstane receptor in protection against bile acid toxicity. J Biol Chem 278:45062-45071.
    • (2003) J Biol Chem , vol.278 , pp. 45062-45071
    • Guo, G.L.1    Lambert, G.2    Negishi, M.3    Ward, J.M.4    Brewer Jr., H.B.5    Kliewer, S.A.6    Gonzalez, F.J.7    Sinal, C.J.8
  • 16
    • 0031866357 scopus 로고    scopus 로고
    • Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats
    • Hirohashi T, Suzuki H, Ito K, Ogawa K, Kume K, Shimizu T, and Sugiyama Y (1998) Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats. Mol Pharmacol 53:1068-1075.
    • (1998) Mol Pharmacol , vol.53 , pp. 1068-1075
    • Hirohashi, T.1    Suzuki, H.2    Ito, K.3    Ogawa, K.4    Kume, K.5    Shimizu, T.6    Sugiyama, Y.7
  • 17
    • 3342996554 scopus 로고    scopus 로고
    • Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)
    • Hori S, Ohtsuki S, Tachikawa M, Kimura N, Kondo T, Watanabe M, Nakashima E, and Terasaki T (2004) Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s). J Neurochem 90:526-536.
    • (2004) J Neurochem , vol.90 , pp. 526-536
    • Hori, S.1    Ohtsuki, S.2    Tachikawa, M.3    Kimura, N.4    Kondo, T.5    Watanabe, M.6    Nakashima, E.7    Terasaki, T.8
  • 19
    • 0030694248 scopus 로고    scopus 로고
    • Modulation of liver canalicular transport processes by the tyrosinekinase inhibitor genistein: Implications of genistein metabolism in the rat
    • Jäger W, Winter O, Halper B, Salamon A, Sartori M, Gajdzik L, Hamilton G, Theyer G, Graf J, and Thalhammer T (1997) Modulation of liver canalicular transport processes by the tyrosinekinase inhibitor genistein: implications of genistein metabolism in the rat. Hepatology 26:1467-1476.
    • (1997) Hepatology , vol.26 , pp. 1467-1476
    • Jäger, W.1    Winter, O.2    Halper, B.3    Salamon, A.4    Sartori, M.5    Gajdzik, L.6    Hamilton, G.7    Theyer, G.8    Graf, J.9    Thalhammer, T.10
  • 20
    • 0021804301 scopus 로고
    • Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport
    • Jansen PL, Peters WH, and Lamers WH (1985) Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport. Hepatology 5:573-579.
    • (1985) Hepatology , vol.5 , pp. 573-579
    • Jansen, P.L.1    Peters, W.H.2    Lamers, W.H.3
  • 21
    • 0029986408 scopus 로고    scopus 로고
    • Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome
    • Kartenbeck J, Leuschner U, Mayer R, and Keppler D (1996) Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome. Hepatology 23:1061-1066.
    • (1996) Hepatology , vol.23 , pp. 1061-1066
    • Kartenbeck, J.1    Leuschner, U.2    Mayer, R.3    Keppler, D.4
  • 22
    • 0036178106 scopus 로고    scopus 로고
    • Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases
    • Kessler FK, Kessler MR, Auyeung DJ, and Ritter JK (2002) Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases. Drug Metab Dispos 30:324-330.
    • (2002) Drug Metab Dispos , vol.30 , pp. 324-330
    • Kessler, F.K.1    Kessler, M.R.2    Auyeung, D.J.3    Ritter, J.K.4
  • 23
    • 0242469240 scopus 로고    scopus 로고
    • Organic anion-transporting polypeptide (OATP) transporter family and drug disposition
    • Kim RB (2003) Organic anion-transporting polypeptide (OATP) transporter family and drug disposition. Eur J Clin Investig 33:1-5.
    • (2003) Eur J Clin Investig , vol.33 , pp. 1-5
    • Kim, R.B.1
  • 24
    • 0032926354 scopus 로고    scopus 로고
    • Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
    • König J, Rost D, Cui Y, and Keppler D (1999) Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology 29:1156-1163.
    • (1999) Hepatology , vol.29 , pp. 1156-1163
    • König, J.1    Rost, D.2    Cui, Y.3    Keppler, D.4
  • 25
    • 1342310953 scopus 로고    scopus 로고
    • Increased hepatic and renal expressions of multidrug resistance- associated protein 3 in Eisai hyperbilirubinuria rats
    • Kuroda M, Kobayashi Y, Tanaka Y, Itani T, Mifuji R, Araki J, Kaito M, and Adachi Y (2004) Increased hepatic and renal expressions of multidrug resistance-associated protein 3 in Eisai hyperbilirubinuria rats. J Gastroenterol Hepatol 19:146-153.
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 146-153
    • Kuroda, M.1    Kobayashi, Y.2    Tanaka, Y.3    Itani, T.4    Mifuji, R.5    Araki, J.6    Kaito, M.7    Adachi, Y.8
  • 26
    • 4644371364 scopus 로고    scopus 로고
    • Efflux transport systems for organic anions and cations at the blood-CSF barrier
    • Kushura H and Sugiyama Y (2004) Efflux transport systems for organic anions and cations at the blood-CSF barrier. Adv Drug Delivery Rev 56:1741-1763.
    • (2004) Adv Drug Delivery Rev , vol.56 , pp. 1741-1763
    • Kushura, H.1    Sugiyama, Y.2
  • 27
    • 1342344851 scopus 로고    scopus 로고
    • Transporters and renal drug elimination
    • Lee W and Kim RB (2004) Transporters and renal drug elimination. Annu Rev Pharmacol Toxicol 44:137-166.
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 137-166
    • Lee, W.1    Kim, R.B.2
  • 29
    • 17544368685 scopus 로고    scopus 로고
    • Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2 and BCRP (ABCG2) in tissue defense
    • Leslie EM, Deeley RG, and Cole SPC (2005) Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2 and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol 204:216-237.
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 216-237
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.C.3
  • 30
    • 0028113492 scopus 로고
    • Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test
    • Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, and Watkins PB (1994) Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test. Drug Metab Dispos 22:947-955.
    • (1994) Drug Metab Dispos , vol.22 , pp. 947-955
    • Lown, K.S.1    Kolars, J.C.2    Thummel, K.E.3    Barnett, J.L.4    Kunze, K.L.5    Wrighton, S.A.6    Watkins, P.B.7
  • 31
    • 0033664346 scopus 로고    scopus 로고
    • Xenobiotic transport across isolated brain microvessels studied by confocal microscopy
    • Miller DS, Nobmann SN, Gutmann H, Toeroek M, Drewe J, and Fricker G (2000) Xenobiotic transport across isolated brain microvessels studied by confocal microscopy. Mol Pharmacol 58:1357-1367.
    • (2000) Mol Pharmacol , vol.58 , pp. 1357-1367
    • Miller, D.S.1    Nobmann, S.N.2    Gutmann, H.3    Toeroek, M.4    Drewe, J.5    Fricker, G.6
  • 34
    • 0033066688 scopus 로고    scopus 로고
    • MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte
    • Ortiz DF, Li S, Iyer R, Zhang X, Novikoff P, and Arias IM (1999) MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte. Am J Physiol 276:G1493-G1500.
    • (1999) Am J Physiol , vol.276
    • Ortiz, D.F.1    Li, S.2    Iyer, R.3    Zhang, X.4    Novikoff, P.5    Arias, I.M.6
  • 37
    • 0037665280 scopus 로고    scopus 로고
    • Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity
    • Potschka H, Fedrowitz M, and Löscher W (2003) Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity. J Pharmacol Exp Ther 306:124-131.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 124-131
    • Potschka, H.1    Fedrowitz, M.2    Löscher, W.3
  • 38
    • 0034982907 scopus 로고    scopus 로고
    • Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2
    • Rausch-Derra LC, Hartley DP, Meier PJ, and Klaassen CD (2001) Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2. Hepatology 33:1469-1478.
    • (2001) Hepatology , vol.33 , pp. 1469-1478
    • Rausch-Derra, L.C.1    Hartley, D.P.2    Meier, P.J.3    Klaassen, C.D.4
  • 42
    • 0037379362 scopus 로고    scopus 로고
    • Bile salt transporters: Molecular characterization, function and regulation
    • Trauner M and Boyer JL (2003) Bile salt transporters: molecular characterization, function and regulation. Physiol Rev 83:633-671.
    • (2003) Physiol Rev , vol.83 , pp. 633-671
    • Trauner, M.1    Boyer, J.L.2
  • 43
    • 0037855831 scopus 로고    scopus 로고
    • Induction of hepatic phase II drug-metabolizing enzymes by 1,7-phenanthroline in rats is accompanied by induction of MRP3
    • Wang S, Hartley DP, Ciccotto SL, Vincent SH, Franklin RB, and Kim MS (2003) Induction of hepatic phase II drug-metabolizing enzymes by 1,7-phenanthroline in rats is accompanied by induction of MRP3. Drug Metab Dispos 31:773-775.
    • (2003) Drug Metab Dispos , vol.31 , pp. 773-775
    • Wang, S.1    Hartley, D.P.2    Ciccotto, S.L.3    Vincent, S.H.4    Franklin, R.B.5    Kim, M.S.6
  • 44
    • 0036707615 scopus 로고    scopus 로고
    • Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment
    • Xiong H, Suzuki H, Sugiyama Y, Meier PJ, Pollack GM, and Brouwer KLR (2002) Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment. Drug Metab Dispos 30:962-969.
    • (2002) Drug Metab Dispos , vol.30 , pp. 962-969
    • Xiong, H.1    Suzuki, H.2    Sugiyama, Y.3    Meier, P.J.4    Pollack, G.M.5    Brouwer, K.L.R.6
  • 45
    • 0034623293 scopus 로고    scopus 로고
    • Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells
    • Zhang Y, Han H, Elmquist WF, and Miller DW (2000) Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells. Brain Res 876:148-153.
    • (2000) Brain Res , vol.876 , pp. 148-153
    • Zhang, Y.1    Han, H.2    Elmquist, W.F.3    Miller, D.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.