Drug metabolism in hepatocyte sandwich cultures of rats and humans

Biochemical Pharmacology

Volumn 54, Issue 7, 1997, Pages 761-772

  Kern, Armin ^a   Bader, A ^b   Pichlmayr, R ^b   Sewing, K F ^b  

^a BAYER AG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Cytochrome P 450; Double gel; Induction; Phase II transferases; Primary culture; Rifampicin

Indexed keywords

7 ETHOXYCOUMARIN DEETHYLASE; CYTOCHROME P450; ETHOXYRESORUFIN DEETHYLASE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; RIFAMPICIN; SULFOTRANSFERASE; TESTOSTERONE;

ADULT; AGED; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIVER CELL CULTURE; LIVER METABOLISM; MALE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RAT; TECHNIQUE;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FEMALE; GLUCURONOSYLTRANSFERASE; HUMANS; LIVER; MALE; MIDDLE AGED; RATS; RATS, WISTAR; RIFAMPIN;

EID: 0030763543     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00204-9     Document Type: Article

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