-
1
-
-
0028342805
-
Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: Evidence against direct drug extrusion from the plasma membrane
-
Altenberg GA, Vanoye CG, Horton JK, and Reuss L (1994) Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: evidence against direct drug extrusion from the plasma membrane. Proc Natl Acad Sci USA 91:4654-4657.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4654-4657
-
-
Altenberg, G.A.1
Vanoye, C.G.2
Horton, J.K.3
Reuss, L.4
-
2
-
-
0034822280
-
P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes
-
Annaert PP, Turncliff R, Booth C, Thakker DR, and Brouwer KLR (2001) P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes. Drug Metab Dispos 29:1277-1283.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1277-1283
-
-
Annaert, P.P.1
Turncliff, R.2
Booth, C.3
Thakker, D.R.4
Brouwer, K.L.R.5
-
3
-
-
0028807793
-
Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes
-
Chieli E, Romiti N, Cervelli F, and Tongiani R (1995) Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes. Life Sci 57:1741-1751.
-
(1995)
Life Sci
, vol.57
, pp. 1741-1751
-
-
Chieli, E.1
Romiti, N.2
Cervelli, F.3
Tongiani, R.4
-
4
-
-
0034627219
-
Carrier-mediated uptake of rhodamine 123: Implications on its use for MDR research
-
Cho C-W, Liu Y, Yan X, Henthorn T, and Ng K-Y (2000) Carrier-mediated uptake of rhodamine 123: implications on its use for MDR research. Biochem Biophys Res Commun 279:124-130.
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 124-130
-
-
Cho, C.-W.1
Liu, Y.2
Yan, X.3
Henthorn, T.4
Ng, K.-Y.5
-
5
-
-
0032544087
-
Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein
-
Conseil G, Baubichon-Cortay H, Dayan G, Jault J-M, Barron D, and Di Pietro A (1998) Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein. Proc Natl Acad Sci USA 95:9831-9836.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9831-9836
-
-
Conseil, G.1
Baubichon-Cortay, H.2
Dayan, G.3
Jault, J.-M.4
Barron, D.5
Di Pietro, A.6
-
6
-
-
0032793959
-
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
-
Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, and Kim RB (1999) OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab Dispos 27:866-871.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 866-871
-
-
Cvetkovic, M.1
Leake, B.2
Fromm, M.F.3
Wilkinson, G.R.4
Kim, R.B.5
-
7
-
-
0035815578
-
2,5]-enkephalin at the murine blood-brain barrier by in situ perfusion
-
2,5]- enkephalin at the murine blood-brain barrier by in situ perfusion. Neurosci Lett 301:155-158.
-
(2001)
Neurosci Lett
, vol.301
, pp. 155-158
-
-
Dagenais, C.1
Ducharme, J.2
Pollack, G.M.3
-
8
-
-
0032885452
-
Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein
-
Doppenschmitt S, Spahn-Langguth H, Regårdh CG, and Langguth P (1999) Role of P-glycoprotein-mediated secretion in absorptive drug permeability: an approach using passive membrane permeability and affinity to P-glycoprotein. J Pharm Sci 88:1067-1072.
-
(1999)
J Pharm Sci
, vol.88
, pp. 1067-1072
-
-
Doppenschmitt, S.1
Spahn-Langguth, H.2
Regårdh, C.G.3
Langguth, P.4
-
9
-
-
0029047741
-
Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells
-
Fardel O, Lecureur V, Loyer P, and Guillouzo A (1995) Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells. Biochem Pharmacol 49:1255-1260.
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 1255-1260
-
-
Fardel, O.1
Lecureur, V.2
Loyer, P.3
Guillouzo, A.4
-
10
-
-
0034235341
-
Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2
-
Fattinger K, Cattori V, Hagenbuch B, Meier PJ, and Stieger B (2000) Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2. Hepatology 32:82-86.
-
(2000)
Hepatology
, vol.32
, pp. 82-86
-
-
Fattinger, K.1
Cattori, V.2
Hagenbuch, B.3
Meier, P.J.4
Stieger, B.5
-
11
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B, Eichelbaum M, Fritz P, Kreichgauer HP, von Richter O, Zundler J, and Kroemer HK (1999) The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Investig 104:147-153.
-
(1999)
J Clin Investig
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
Von Richter, O.5
Zundler, J.6
Kroemer, H.K.7
-
13
-
-
0035108342
-
Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats
-
Hanafy A, Langguth P, and Spahn-Langguth H (2001) Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats. Eur J Pharm Sci 12:405-415.
-
(2001)
Eur J Pharm Sci
, vol.12
, pp. 405-415
-
-
Hanafy, A.1
Langguth, P.2
Spahn-Langguth, H.3
-
14
-
-
0025092259
-
Interactions in the renal and biliary elimination of digoxin: Stereoselective difference between quinine and quinidine
-
Hedman A, Angelin B, Arvidsson A, Dahlqvist R, and Nilsson B (1990) Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine. Clin Pharmacol Ther 47:20-26.
-
(1990)
Clin Pharmacol Ther
, vol.47
, pp. 20-26
-
-
Hedman, A.1
Angelin, B.2
Arvidsson, A.3
Dahlqvist, R.4
Nilsson, B.5
-
15
-
-
0019480519
-
Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy
-
Johnson LV, Walsh ML, Bockus BJ, and Chen LB (1981) Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J Cell Biol 88:526-535.
-
(1981)
J Cell Biol
, vol.88
, pp. 526-535
-
-
Johnson, L.V.1
Walsh, M.L.2
Bockus, B.J.3
Chen, L.B.4
-
16
-
-
14044261480
-
Drug-drug interactions involving the membrane transport process
-
Kusuhara H and Sugiyama Y (2001) Drug-drug interactions involving the membrane transport process. Drugs Pharm Sci 116:123-188.
-
(2001)
Drugs Pharm Sci
, vol.116
, pp. 123-188
-
-
Kusuhara, H.1
Sugiyama, Y.2
-
17
-
-
0006232427
-
Analysis of variance with just summary statistics as input
-
Larson DA (1992) Analysis of variance with just summary statistics as input. Am Stat 46:151-152.
-
(1992)
Am Stat
, vol.46
, pp. 151-152
-
-
Larson, D.A.1
-
18
-
-
0033017134
-
Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats
-
Liu X, Chism JP, LeCluyse EL, Brouwer KR, and Brouwer KLR (1999) Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats. Drug Metab Dispos 27:637-644.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 637-644
-
-
Liu, X.1
Chism, J.P.2
LeCluyse, E.L.3
Brouwer, K.R.4
Brouwer, K.L.R.5
-
19
-
-
0034600237
-
Effect of bioflavonoids on vincristine transport across blood-brain barrier
-
Mitsunaga Y, Takanaga H, Matsuo H, Naito M, Tsuruo T, Ohtani H, and Sawada Y (2000) Effect of bioflavonoids on vincristine transport across blood-brain barrier. Eur J Pharmacol 395:193-201.
-
(2000)
Eur J Pharmacol
, vol.395
, pp. 193-201
-
-
Mitsunaga, Y.1
Takanaga, H.2
Matsuo, H.3
Naito, M.4
Tsuruo, T.5
Ohtani, H.6
Sawada, Y.7
-
20
-
-
0030886124
-
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
-
Noé B, Hagenbuch B, Stieger B, and Meier PJ (1997) Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci USA 94:10346-10350.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10346-10350
-
-
Noé, B.1
Hagenbuch, B.2
Stieger, B.3
Meier, P.J.4
-
21
-
-
0027132062
-
Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells
-
Phang JM, Poore CM, Lopaczynska J, and Yeh GC (1993) Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells. Cancer Res 53:5977-5981.
-
(1993)
Cancer Res
, vol.53
, pp. 5977-5981
-
-
Phang, J.M.1
Poore, C.M.2
Lopaczynska, J.3
Yeh, G.C.4
-
22
-
-
0032819955
-
Localization and function of the organic anion-transporting polypeptide oatp2 in rat liver
-
Reichel C, Gao B, Van Montfoort J, Cattori V, Rahner C, Hagenbuch B, Stieger B, Kamisako T, and Meier PJ (1999) Localization and function of the organic anion-transporting polypeptide oatp2 in rat liver. Gastroenterology 117:688-695.
-
(1999)
Gastroenterology
, vol.117
, pp. 688-695
-
-
Reichel, C.1
Gao, B.2
Van Montfoort, J.3
Cattori, V.4
Rahner, C.5
Hagenbuch, B.6
Stieger, B.7
Kamisako, T.8
Meier, P.J.9
-
23
-
-
0034940754
-
The role of P-glycoprotein in limiting intestinal absorption of digoxin in rats
-
Sababi M, Borga O, and Hultkvist-Bengtsson U (2001) The role of P-glycoprotein in limiting intestinal absorption of digoxin in rats. Eur J Pharm Sci 14:21-27.
-
(2001)
Eur J Pharm Sci
, vol.14
, pp. 21-27
-
-
Sababi, M.1
Borga, O.2
Hultkvist-Bengtsson, U.3
-
24
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
-
Schuetz EG, Beck WT, and Schuetz JD (1996) Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol Pharmacol 49:311-318.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 311-318
-
-
Schuetz, E.G.1
Beck, W.T.2
Schuetz, J.D.3
-
25
-
-
0017101039
-
Preparation of isolated rat liver cells
-
Seglen PO (1976) Preparation of isolated rat liver cells. Methods Cell Biol 13:29-83.
-
(1976)
Methods Cell Biol
, vol.13
, pp. 29-83
-
-
Seglen, P.O.1
-
26
-
-
0030782511
-
Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
-
Shapiro AB and Ling V (1997) Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur J Biochem 250:130-137.
-
(1997)
Eur J Biochem
, vol.250
, pp. 130-137
-
-
Shapiro, A.B.1
Ling, V.2
-
27
-
-
0030939088
-
Expression of the multidrug resistance genes in the liver
-
Silverman JA and Schrenk D (1997) Expression of the multidrug resistance genes in the liver. FASEB J 11:308-312.
-
(1997)
FASEB J
, vol.11
, pp. 308-312
-
-
Silverman, J.A.1
Schrenk, D.2
-
28
-
-
0035146553
-
Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia
-
Stephens RH, O'Neill CA, Warhurst A, Carlson GL, Rowland M, and Warhurst G (2001) Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia. J Pharmacol Exp Ther 296:584-591.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 584-591
-
-
Stephens, R.H.1
O'Neill, C.A.2
Warhurst, A.3
Carlson, G.L.4
Rowland, M.5
Warhurst, G.6
-
29
-
-
0036146641
-
Effect of 17β-estradiol-D-17β-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates
-
Sugiyama D, Kusuhara H, Shitara Y, Abe T, and Sugiyama Y (2002) Effect of 17β-estradiol-D-17β-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates. Drug Metab Dispos 30:220-223.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 220-223
-
-
Sugiyama, D.1
Kusuhara, H.2
Shitara, Y.3
Abe, T.4
Sugiyama, Y.5
-
30
-
-
0023447098
-
Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuro T, Hamada H, Gottesman MM, Pastan I, and Willingham MC (1987) Cellular localization of the multidrug resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84:7735-7738.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuro, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
31
-
-
0041402719
-
Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells
-
Troutman MD and Thakker DR (2003) Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells. Pharm Res (NY) 20:1192-1199.
-
(2003)
Pharm Res (NY)
, vol.20
, pp. 1192-1199
-
-
Troutman, M.D.1
Thakker, D.R.2
-
32
-
-
3242740859
-
Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes
-
Turncliff RZ, Meier PJ, and Brouwer KLR (2004) Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes. Drug Metab Dispos 32:834-839.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 834-839
-
-
Turncliff, R.Z.1
Meier, P.J.2
Brouwer, K.L.R.3
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