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Volumn 58, Issue 2, 2000, Pages 399-415

Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells

(9) Burczynski, Michael E a McMillian, Michael a Ciervo, Joe a Li, Li a,c Parker, James B a Dunn II, Robert T b Hicken, Sam b Farr, Spencer b Johnson, Mark D a

a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT (United States)

b Phase 1 Molecular Toxicology Inc (United States)

c MERCK RESEARCH LABORATORIES (United States)

Author keywords

CDNA microarrays; DNA damaging agents; Gene expression profiling; Non steroidal anti inflammatory agents; Toxicogenomics

Indexed keywords

CISPLATIN; CYCLINE; DIFLUNISAL; FLUFENAMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN P21; PROTEIN P53; TOXIC SUBSTANCE; XENOBIOTIC AGENT;

ALGORITHM; APOPTOSIS; ARTICLE; CELL CYCLE; CELL STRAIN HEPG2; CELL STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; DNA FINGERPRINTING; DNA MICROARRAY; DNA REPAIR; GENE EXPRESSION; GENE FUNCTION; GENE INDUCTION; GENE REPRESSION; GENETIC SELECTION; GENETIC TOXICOLOGY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; TRANSACTIVATION; XENOBIOTIC METABOLISM;

ALGORITHMS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARCINOMA, HEPATOCELLULAR; CISPLATIN; DNA DAMAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; TUMOR CELLS, CULTURED;

EID: 0034518116 PISSN: 10966080 EISSN: None Source Type: Journal
DOI: 10.1093/toxsci/58.2.399 Document Type: Article

Times cited : (240)

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