Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes

Drug Metabolism and Disposition

Volumn 26, Issue 1, 1998, Pages 1-4

  Chauret, Nathalie ^a   Gauthier, Annick ^b   Nicoll Griffith, Deborah A ^b  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; CHLORZOXAZONE; COUMARIN; CYTOCHROME P450; DEXTROMETHORPHAN; DIMETHYL SULFOXIDE; MEPHENYTOIN; METHANOL; ORGANIC SOLVENT; PHENACETIN; TESTOSTERONE;

ARTICLE; CATALYSIS; DEMETHYLATION; DRUG DISPOSITION; DRUG EFFECT; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN TISSUE; HYDROXYLATION; IN VITRO STUDY; LIVER METABOLISM; LIVER MICROSOME; METABOLIC REGULATION; PRIORITY JOURNAL; SOLUBILIZATION;

ACETONITRILES; ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; DIMETHYL SULFOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROXYLATION; METHANOL; MICROSOMES, LIVER; SOLVENTS;

EID: 0031940804     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

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