Effects of organic solvents on the activities of cytochrome P450 isoforms, UDP-dependent glucuronyl transferase, and phenol sulfotransferase in human hepatocytes

Drug Metabolism and Disposition

Volumn 29, Issue 2, 2001, Pages 141-144

  Easterbrook, Judy ^a   Lu, Chuang ^a   Sakai, Yumiko ^a   Li, Albert P ^a  

^a In Vitro Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; ARYL SULFOTRANSFERASE; COUMARIN; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME P450 ISOENZYME; DEXTROMETHORPHAN; DIMETHYL SULFOXIDE; GLUCURONOSYLTRANSFERASE; MEPHENYTOIN; METHANOL; ORGANIC SOLVENT; PHENACETIN; TESTOSTERONE; TOLBUTAMIDE; UMBELLIFERONE; URIDINE DIPHOSPHATE;

ARTICLE; CONCENTRATION RESPONSE; DEMETHYLATION; DRUG CONJUGATION; DRUG GLUCURONIDATION; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; SULFATION;

ACETONITRILES; ADULT; AGED; AGED, 80 AND OVER; ARYLSULFOTRANSFERASE; CYTOCHROME P-450 ENZYME SYSTEM; DIMETHYL SULFOXIDE; ETHANOL; FEMALE; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; HUMANS; ISOENZYMES; MALE; METHANOL; MIDDLE AGED; SOLVENTS; SUBSTRATE SPECIFICITY;

EID: 0035146956     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

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