-
1
-
-
0014353859
-
The energy charge of the adenylate pool as a regulatory parameter: Interaction with feedback modifiers
-
Atkinson DE (1968) The energy charge of the adenylate pool as a regulatory parameter: interaction with feedback modifiers. Biochemistry 7:4030-4034.
-
(1968)
Biochemistry
, vol.7
, pp. 4030-4034
-
-
Atkinson, D.E.1
-
2
-
-
0021201874
-
Isolation, culture and characterization of adult human hepatocytes from surgical liver biopsies
-
Ballet F, Bouma ME, Wang SR, Amit N, Marais J and Infante R (1984) Isolation, culture and characterization of adult human hepatocytes from surgical liver biopsies. Hepatology 4:849-854.
-
(1984)
Hepatology
, vol.4
, pp. 849-854
-
-
Ballet, F.1
Bouma, M.E.2
Wang, S.R.3
Amit, N.4
Marais, J.5
Infante, R.6
-
3
-
-
0024408814
-
Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4
-
Bargetzi M, Aoyama T, Gonzalez F and Meyer U (1989) Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4. Clin Phamacol Ther 46:521-527.
-
(1989)
Clin Phamacol Ther
, vol.46
, pp. 521-527
-
-
Bargetzi, M.1
Aoyama, T.2
Gonzalez, F.3
Meyer, U.4
-
4
-
-
0026080681
-
Liver slices in dynamic organ culture. II. An in vitro cellular technique for the study of integrated drug metabolism using human tissue
-
Barr J, Weir AJ, Brendel K and Sipes IG (1991) Liver slices in dynamic organ culture. II. An in vitro cellular technique for the study of integrated drug metabolism using human tissue. Xenobiotica 21:341-350.
-
(1991)
Xenobiotica
, vol.21
, pp. 341-350
-
-
Barr, J.1
Weir, A.J.2
Brendel, K.3
Sipes, I.G.4
-
5
-
-
0014645531
-
High-yield preparation of isolated rat liver parenchymal cells: A biochemical and fine structural study
-
Berry MN and Friend DS (1969) High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. J Cell Biol 43:506-520.
-
(1969)
J Cell Biol
, vol.43
, pp. 506-520
-
-
Berry, M.N.1
Friend, D.S.2
-
6
-
-
0026566828
-
Techniques for pharmacological and toxicological studies with isolated hepatocyte suspensions
-
Berry MN, Halls HJ and Grivell MB (1992) Techniques for pharmacological and toxicological studies with isolated hepatocyte suspensions. Life Sci 51:1-16.
-
(1992)
Life Sci
, vol.51
, pp. 1-16
-
-
Berry, M.N.1
Halls, H.J.2
Grivell, M.B.3
-
7
-
-
84948378785
-
Preparation of parenchymal and non-parenchymal cells from adult human liver: Morphological and biochemical characteristics
-
Bojar H, Basler M, Fuchs F, Dreyfürst R, Staib W and Broelsch C (1976) Preparation of parenchymal and non-parenchymal cells from adult human liver: morphological and biochemical characteristics. J Clin Chem Clin Biochem 14:527-532.
-
(1976)
J Clin Chem Clin Biochem
, vol.14
, pp. 527-532
-
-
Bojar, H.1
Basler, M.2
Fuchs, F.3
Dreyfürst, R.4
Staib, W.5
Broelsch, C.6
-
8
-
-
0030899604
-
Surgical treatment of giant hemangiomas of the liver
-
Brouwers MAM, Peeters PMJG, De Jong KP, Haagsma EB, Klompmaker IJ, Bijleveld CMA, Zwaveling JH and Slooff MJH (1997) Surgical treatment of giant hemangiomas of the liver. Br J Surg 84:314-316.
-
(1997)
Br J Surg
, vol.84
, pp. 314-316
-
-
Brouwers, M.A.M.1
Peeters, P.M.J.G.2
De Jong, K.P.3
Haagsma, E.B.4
Klompmaker, I.J.5
Bijleveld, C.M.A.6
Zwaveling, J.H.7
Slooff, M.J.H.8
-
9
-
-
0017672290
-
The metabolic integrity of hepatocytes in sustained incubations
-
Dickson AJ and Pogson CI (1977) The metabolic integrity of hepatocytes in sustained incubations. FEBS Lett 83:27-32.
-
(1977)
FEBS Lett
, vol.83
, pp. 27-32
-
-
Dickson, A.J.1
Pogson, C.I.2
-
10
-
-
0027994150
-
A new technique for isolating and culturing human hepatocytes from whole or split livers not used for transplantation
-
Dorko K, Freeswick PD, Bartoli F, Cicalese L, Bardsley BA, Tzakis A and Nussler AK (1994) A new technique for isolating and culturing human hepatocytes from whole or split livers not used for transplantation. Cell Transplant 3:387-395.
-
(1994)
Cell Transplant
, vol.3
, pp. 387-395
-
-
Dorko, K.1
Freeswick, P.D.2
Bartoli, F.3
Cicalese, L.4
Bardsley, B.A.5
Tzakis, A.6
Nussler, A.K.7
-
11
-
-
0028863043
-
Quantitative differences in phase I and II metabolism between rat precision-cut liver slices and isolated hepatocytes
-
Ekins S, Murray GI, Burke MD, Williams JA, Marchant NC and Hawksworth GM (1995) Quantitative differences in phase I and II metabolism between rat precision-cut liver slices and isolated hepatocytes. Drug Metab Dispos 23:1274-1279.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 1274-1279
-
-
Ekins, S.1
Murray, G.I.2
Burke, M.D.3
Williams, J.A.4
Marchant, N.C.5
Hawksworth, G.M.6
-
12
-
-
0026355132
-
Valproic acid hepatotoxicity in human liver slices
-
Fisher R, Nau H, Gandolfi AJ, Putnam CW and Brendel K (1991) Valproic acid hepatotoxicity in human liver slices. Drug Chem Toxicol 14:375-394.
-
(1991)
Drug Chem Toxicol
, vol.14
, pp. 375-394
-
-
Fisher, R.1
Nau, H.2
Gandolfi, A.J.3
Putnam, C.W.4
Brendel, K.5
-
13
-
-
0001983466
-
Dynamic organ culture is superior to multiwell plate culture for maintaining precision-cut tissue slices. Optimization of tissue slice culture. Part I
-
Fisher RL, Shaughnessy RP, Jenkins PM, Austin ML, Roth GL, Gandolfi AJ and Brendel K (1995) Dynamic organ culture is superior to multiwell plate culture for maintaining precision-cut tissue slices. Optimization of tissue slice culture. Part I. Toxicol Methods 5:99-113
-
(1995)
Toxicol Methods
, vol.5
, pp. 99-113
-
-
Fisher, R.L.1
Shaughnessy, R.P.2
Jenkins, P.M.3
Austin, M.L.4
Roth, G.L.5
Gandolfi, A.J.6
Brendel, K.7
-
14
-
-
0029561479
-
Comparison of human hepatocytes isolated from livers accepted or discarded for orthotopic transplantation
-
Groothuis GMM, Sandker GW, Pruim J, Weert B, Slooff MJH and Meijer DKF (1995) Comparison of human hepatocytes isolated from livers accepted or discarded for orthotopic transplantation. Toxicol In Vitro 9:951-958.
-
(1995)
Toxicol In Vitro
, vol.9
, pp. 951-958
-
-
Groothuis, G.M.M.1
Sandker, G.W.2
Pruim, J.3
Weert, B.4
Slooff, M.J.H.5
Meijer, D.K.F.6
-
15
-
-
0019913556
-
High yield preparation of isolated human adult hepatocytes by enzymatic perfusion of the liver
-
Guguen-Guillouzo C, Campion JP, Brissot P, Glaise D, Launois B, Bourel M and Guillouzo A (1982) High yield preparation of isolated human adult hepatocytes by enzymatic perfusion of the liver. Cell Biol Int Rep 6:625-628.
-
(1982)
Cell Biol Int Rep
, vol.6
, pp. 625-628
-
-
Guguen-Guillouzo, C.1
Campion, J.P.2
Brissot, P.3
Glaise, D.4
Launois, B.5
Bourel, M.6
Guillouzo, A.7
-
16
-
-
0025043312
-
Long-term culture of functional hepatocytes
-
Guillouzo A, Morel F, Ratanasavanh D, Chesne C and Guguen-Guillouzo C (1990) Long-term culture of functional hepatocytes. Toxicol In Vitro 4:415-427.
-
(1990)
Toxicol In Vitro
, vol.4
, pp. 415-427
-
-
Guillouzo, A.1
Morel, F.2
Ratanasavanh, D.3
Chesne, C.4
Guguen-Guillouzo, C.5
-
17
-
-
0025615128
-
Primary culture of adult rat hepatocytes after 48-hour preservation of the liver with cold UW solution
-
Guyomard C, Chesne C, Meunier B, Fautrel A, Clerc C, Morel F, Rissel M, Campion JP and Guillouzo A (1990) Primary culture of adult rat hepatocytes after 48-hour preservation of the liver with cold UW solution. Hepatology 12:1329-1336.
-
(1990)
Hepatology
, vol.12
, pp. 1329-1336
-
-
Guyomard, C.1
Chesne, C.2
Meunier, B.3
Fautrel, A.4
Clerc, C.5
Morel, F.6
Rissel, M.7
Campion, J.P.8
Guillouzo, A.9
-
18
-
-
0025801229
-
Maintenance of mixed-function oxidase and conjugation enzyme activities in hepatocyte cultures prepared from normal and diseased human liver
-
Iqbal S, Elcombe CR and Elias E (1991) Maintenance of mixed-function oxidase and conjugation enzyme activities in hepatocyte cultures prepared from normal and diseased human liver. J Hepatol 12:336-343.
-
(1991)
J Hepatol
, vol.12
, pp. 336-343
-
-
Iqbal, S.1
Elcombe, C.R.2
Elias, E.3
-
19
-
-
84939669716
-
Untersuchungen über den Stoffwechsel der Aminosäuren im Tierkörper
-
Krebs HA (1933) Untersuchungen über den Stoffwechsel der Aminosäuren im Tierkörper. Hoppe-Seyler Z 217:190-227.
-
(1933)
Hoppe-Seyler Z
, vol.217
, pp. 190-227
-
-
Krebs, H.A.1
-
20
-
-
0019313649
-
A new instrument for the rapid preparation of tissue slices
-
Krumdieck CL, dos Santos JE and Ho KJ (1980) A new instrument for the rapid preparation of tissue slices. Anal Biochem 104:118-123.
-
(1980)
Anal Biochem
, vol.104
, pp. 118-123
-
-
Krumdieck, C.L.1
Dos Santos, J.E.2
Ho, K.J.3
-
21
-
-
0024356618
-
Comparison of taurocholate accumulation in cultured hepatocytes of pig, rat and man
-
Kwekkeboom J, Princen HMG, Van Voorthuizen EM, Meijer P and Kempen HJM (1989) Comparison of taurocholate accumulation in cultured hepatocytes of pig, rat and man. Biochem Biophys Res Commun 162:619-625.
-
(1989)
Biochem Biophys Res Commun
, vol.162
, pp. 619-625
-
-
Kwekkeboom, J.1
Princen, H.M.G.2
Van Voorthuizen, E.M.3
Meijer, P.4
Kempen, H.J.M.5
-
23
-
-
0010604484
-
Transport of drugs, proteins and drug-protein conjugates
-
(Ballet F and Thurmann RG eds) INSERM/John Libbey, London
-
Meijer DKF and Nijssen HMJ (1991) Transport of drugs, proteins and drug-protein conjugates, in Research in Perfused Liver (Ballet F and Thurmann RG eds) pp 165-208, INSERM/John Libbey, London.
-
(1991)
Research in Perfused Liver
, pp. 165-208
-
-
Meijer, D.K.F.1
Nijssen, H.M.J.2
-
24
-
-
0028662025
-
P450 in the rat and man: Methods of investigation, substrate specificities and relevance to cancer
-
Nedelcheva V and Gut I (1994) P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer. Xenobiotica 24:1151-1175.
-
(1994)
Xenobiotica
, vol.24
, pp. 1151-1175
-
-
Nedelcheva, V.1
Gut, I.2
-
25
-
-
84943476436
-
Monoethylglycinexylidide formation kinetics: A novel approach to assessment of liver function
-
Oellerich M, Raude E, Burdelski M, Schulz M, Schmidt FW, Ringe B, Lamesch P, Pichlmayr R, Raith H, Scheruhn M (1987) Monoethylglycinexylidide formation kinetics: a novel approach to assessment of liver function. J Clin Chem Clin Biochem 25:845-853.
-
(1987)
J Clin Chem Clin Biochem
, vol.25
, pp. 845-853
-
-
Oellerich, M.1
Raude, E.2
Burdelski, M.3
Schulz, M.4
Schmidt, F.W.5
Ringe, B.6
Lamesch, P.7
Pichlmayr, R.8
Raith, H.9
Scheruhn, M.10
-
26
-
-
0001736713
-
Human liver slices express the same lidocaine biotransformation rate as isolated human hepatocytes
-
Olinga P, Merema MT, Meijer DKF, Slooff MJH and Groothuis GMM (1993) Human liver slices express the same lidocaine biotransformation rate as isolated human hepatocytes. ATLA 21:466-468.
-
(1993)
ATLA
, vol.21
, pp. 466-468
-
-
Olinga, P.1
Merema, M.T.2
Meijer, D.K.F.3
Slooff, M.J.H.4
Groothuis, G.M.M.5
-
27
-
-
0000298996
-
Use of human liver slices and hepatocytes in transport and metabolism studies
-
(Goldberg AM and van Zutphen LFM eds) Mary Ann Liebert Publishers, New York
-
Olinga P, Merema MT, Sandker GW, Slooff MJH, Meijer DKF and Groothuis GMM (1995) Use of human liver slices and hepatocytes in transport and metabolism studies, in The World Congress on Alternatives and Animal Use in the Life Sciences: Education, Research, Testing (Goldberg AM and van Zutphen LFM eds) pp 197-203, Mary Ann Liebert Publishers, New York.
-
(1995)
The World Congress on Alternatives and Animal Use in the Life Sciences: Education, Research, Testing
, pp. 197-203
-
-
Olinga, P.1
Merema, M.T.2
Sandker, G.W.3
Slooff, M.J.H.4
Meijer, D.K.F.5
Groothuis, G.M.M.6
-
28
-
-
0344971908
-
The effect of short-term cold storage on metabolic functions of isolated hepatocytes and slices of human and monkey liver
-
in press
-
Olinga P, Merema MT, Hof IH, de Jager MH, de Jong KP, Slooff MJH, Meijer DKF and Groothuis GMM (1998). The effect of short-term cold storage on metabolic functions of isolated hepatocytes and slices of human and monkey liver. Xenobiotica, in press.
-
(1998)
Xenobiotica
-
-
Olinga, P.1
Merema, M.T.2
Hof, I.H.3
De Jager, M.H.4
De Jong, K.P.5
Slooff, M.J.H.6
Meijer, D.K.F.7
Groothuis, G.M.M.8
-
29
-
-
0025249973
-
The maintenance of cytochrome P-450 in rat hepatocyte culture: Some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system
-
Paine AJ (1991) The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system. Chem Biol Interact 74:1-31.
-
(1991)
Chem Biol Interact
, vol.74
, pp. 1-31
-
-
Paine, A.J.1
-
30
-
-
0028818410
-
Precision cut liver slices: Applications in pharmacology and toxicology
-
Parrish AR, Gandolfi AJ and Brendel K (1995) Precision cut liver slices: applications in pharmacology and toxicology. Life Sci 57:1887-1901.
-
(1995)
Life Sci
, vol.57
, pp. 1887-1901
-
-
Parrish, A.R.1
Gandolfi, A.J.2
Brendel, K.3
-
31
-
-
0028114740
-
Use of in vitro human metabolism studies in drug development: An industrial perspective
-
Rodrigues AD (1994) Use of in vitro human metabolism studies in drug development: an industrial perspective. Biochem Pharmacol 48:2147-2156.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 2147-2156
-
-
Rodrigues, A.D.1
-
32
-
-
0002162030
-
Cultures of human hepatocytes in in vitro pharmaco-toxicology
-
(Rogiers V, Sonck W, Shephard E and Vercruysse A eds) VUBPRESS, Brussels
-
Rogiers V (1993) Cultures of human hepatocytes in in vitro pharmaco-toxicology, in Human Cells in In Vitro Pharmaco-toxicology (Rogiers V, Sonck W, Shephard E and Vercruysse A eds) pp 77-115, VUBPRESS, Brussels.
-
(1993)
Human Cells in In Vitro Pharmaco-toxicology
, pp. 77-115
-
-
Rogiers, V.1
-
33
-
-
0026517058
-
Drug transport, viability and morphology of isolated rat hepatocytes preserved for 24 hours in University of Wisconsin solution
-
Sandker GW, Slooff MJH and Groothuis GMM (1992) Drug transport, viability and morphology of isolated rat hepatocytes preserved for 24 hours in University of Wisconsin solution. Biochem Pharmacol 43:1479-1485.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1479-1485
-
-
Sandker, G.W.1
Slooff, M.J.H.2
Groothuis, G.M.M.3
-
34
-
-
0028347408
-
Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: Analysis of interspecies variability and comparison with metabolism in vivo
-
Sandker GW, Vos RME, Delbressine LPC, Slooff MJH, Meijer DKF and Groothuis GMM (1994a) Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: analysis of interspecies variability and comparison with metabolism in vivo. Xenobiotica 24:143-155.
-
(1994)
Xenobiotica
, vol.24
, pp. 143-155
-
-
Sandker, G.W.1
Vos, R.M.E.2
Delbressine, L.P.C.3
Slooff, M.J.H.4
Meijer, D.K.F.5
Groothuis, G.M.M.6
-
35
-
-
0028308230
-
Characterization of transport in isolated human hepatocytes: A study with the bile acid taurocholic acid, the uncharged ouabain and the organic cations vecuronium and rocuronium
-
Sandker GW, Weert B, Olinga P, Wolters H, Slooff MJH, Meijer DKF and Groothuis GMM (1994b) Characterization of transport in isolated human hepatocytes: a study with the bile acid taurocholic acid, the uncharged ouabain and the organic cations vecuronium and rocuronium. Biochem Pharmacol 47:2193-2200.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 2193-2200
-
-
Sandker, G.W.1
Weert, B.2
Olinga, P.3
Wolters, H.4
Slooff, M.J.H.5
Meijer, D.K.F.6
Groothuis, G.M.M.7
-
36
-
-
0021801560
-
Dynamic organ culture of precision liver slices for in vitro toxicology
-
Smith P, Gandolfi A, Krumdieck C, Putnam C, Zukowski C, Davis W and Brendel K (1985) Dynamic organ culture of precision liver slices for in vitro toxicology. Life Sci 36:1367-1375.
-
(1985)
Life Sci
, vol.36
, pp. 1367-1375
-
-
Smith, P.1
Gandolfi, A.2
Krumdieck, C.3
Putnam, C.4
Zukowski, C.5
Davis, W.6
Brendel, K.7
-
37
-
-
0019968956
-
Isolation, culture and transplantation of human hepatocytes
-
Strom SC, Jirtle RL, Jones RS, Novicki DL, Rosenberg MR, Novotny A, Irons G, McLain JR and Michalopoulos G (1982) Isolation, culture and transplantation of human hepatocytes. J Noll Cancer Inst 68:771-778.
-
(1982)
J Noll Cancer Inst
, vol.68
, pp. 771-778
-
-
Strom, S.C.1
Jirtle, R.L.2
Jones, R.S.3
Novicki, D.L.4
Rosenberg, M.R.5
Novotny, A.6
Irons, G.7
McLain, J.R.8
Michalopoulos, G.9
-
38
-
-
0027303803
-
Isolation and culture of human hepatocytes from resected liver tissue as a bioreactor for a hybrid artificial liver
-
Takahashi M, Matsue H, Matsushita M, Nakajima Y and Uchino J (1993) Isolation and culture of human hepatocytes from resected liver tissue as a bioreactor for a hybrid artificial liver. Artif Organs 17:653-659.
-
(1993)
Artif Organs
, vol.17
, pp. 653-659
-
-
Takahashi, M.1
Matsue, H.2
Matsushita, M.3
Nakajima, Y.4
Uchino, J.5
-
39
-
-
0027432032
-
Cytochrome P450 induction and metabolism of alkoxyresorufins, ethylmorphine and testosterone in cultured hepatocytes from goats, sheep and cattle
-
van't Klooster GAE, Blaauboer BJ, Noordhoek J and van Mjert ASJPAM (1993) Cytochrome P450 induction and metabolism of alkoxyresorufins, ethylmorphine and testosterone in cultured hepatocytes from goats, sheep and cattle. Biochem Pharmacol 46:1781-1790.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 1781-1790
-
-
Van't Klooster, G.A.E.1
Blaauboer, B.J.2
Noordhoek, J.3
Van Mjert, A.S.J.P.A.M.4
-
40
-
-
0025026967
-
Comparison of cultured human hepatocytes isolated from surgical biopsies or cold-stored organ donor livers
-
Vons C, Pegorier JP, Ivanov MA, Girard J, Melcion C, Cordier A and Franco D (1990) Comparison of cultured human hepatocytes isolated from surgical biopsies or cold-stored organ donor livers. Toxicol In Vitro 4:432-434.
-
(1990)
Toxicol In Vitro
, vol.4
, pp. 432-434
-
-
Vons, C.1
Pegorier, J.P.2
Ivanov, M.A.3
Girard, J.4
Melcion, C.5
Cordier, A.6
Franco, D.7
-
41
-
-
0029123787
-
An improved HPLC assay for the assessment of liver slice metabolic viability using 7-ethoxycoumarin
-
Walsh JS, Patanella JE, Halm KA and Facchine KL (1995) An improved HPLC assay for the assessment of liver slice metabolic viability using 7-ethoxycoumarin. Drug Metab Dispos 23:869-874.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 869-874
-
-
Walsh, J.S.1
Patanella, J.E.2
Halm, K.A.3
Facchine, K.L.4
-
42
-
-
0001483173
-
Versuche an überlebendem Karzinomgewebe
-
Warburg O (1923) Versuche an überlebendem Karzinomgewebe. Biochem Z 142:317-333.
-
(1923)
Biochem Z
, vol.142
, pp. 317-333
-
-
Warburg, O.1
-
43
-
-
0026179354
-
Biotransformation activity in vitrified human liver slices
-
Wishnies SM, Parrish AR, Sipes IG, Gandolfi AJ, Putnam CW, Krumdieck CL and Brendel K (1991) Biotransformation activity in vitrified human liver slices. Cryobiology 28:216-226.
-
(1991)
Cryobiology
, vol.28
, pp. 216-226
-
-
Wishnies, S.M.1
Parrish, A.R.2
Sipes, I.G.3
Gandolfi, A.J.4
Putnam, C.W.5
Krumdieck, C.L.6
Brendel, K.7
-
44
-
-
0028928220
-
Kinetics of drug metabolism in rat liver slices: Rates of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds
-
Worboys PD, Bradbury A and Houston JB (1995) Kinetics of drug metabolism in rat liver slices: rates of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds. Drug Metab Dispos 23:393-397.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 393-397
-
-
Worboys, P.D.1
Bradbury, A.2
Houston, J.B.3
|