The impact of systems approaches on biological problems in drug discovery

Nature Biotechnology

Volumn 22, Issue 10, 2004, Pages 1215-1217

  Hood, Leroy ^a   Perlmutter, Roger M ^b  

^a INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTIC METHOD; DRUG COST; DRUG INDUSTRY; DRUG RESEARCH; NOTE; PATENT; PRIORITY JOURNAL; SYSTEM ANALYSIS;

DRUG DELIVERY SYSTEMS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG INDUSTRY; MODELS, BIOLOGICAL; MOLECULAR BIOLOGY; RESEARCH; SYSTEMS BIOLOGY; SYSTEMS THEORY; TECHNOLOGY, PHARMACEUTICAL;

EID: 5044229321     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1004-1215     Document Type: Note

References (11)

1. Drews, J. Nat. Biotechnol. 14, 1516-1518 (1996).
2. Booth, B. & Zemmel, R. Nat. Rev. Drug Disc. 3, 451-456 (2004).
3. Anonymous. Parexel's Pharmaceutical R&D Statistical Sourcebook 2003/2004, p. 42 (Parexel International Corporation, Waltham, MA, 2003).
4. Weston, A.D. & Hood, L. J. Proteome Res. 3, 179-196 (2004).
5. Weston, A.D., Baliga, N.S., Bonneau, R. & Hood, L. in The Genome of Homo Sapiens, Volume LXVIII, Symposia on Quantitative Biology, 345-357 (Cold Spring Harbor Press, Cold Spring Harbor, NY, 2004).
6. Kunkel, E.J. et al. FASEB J. 18, 1279-1281 (2004).
7. Nicholson, J.K. & Wilson, I.D. Nat. Rev. Drug. Discov. 2, 668-676 (2003).
8. Paez, J.G. et al. Science 304, 1497-1500 (2004).
9. Lynch, T.J. et al. N. Eng. J. Med. 350, 2129-2139 (2004).
10. Drug Week, Pharmaceutical Development, 25 June 2004. http://www.NewsRx. com/
11. Pharmaceutical Industry Profile 2004 (Pharmaceutical Research and Manufacturers of America, Washington, DC, 2004). http://www.phrma.org/ publications/publications//2004-03-31.937.pdf