-
1
-
-
57049117856
-
Cell death and endoplasmic reticulum stress: Disease relevance and therapeutic opportunities
-
Kim I, Xu W, and Reed JC (2008). Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 7, 1013-1030.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 1013-1030
-
-
Kim, I.1
Xu, W.2
Reed, J.C.3
-
2
-
-
77955410103
-
Modeling the endoplasmic reticulum unfolded protein response
-
Onn A and Ron D (2010). Modeling the endoplasmic reticulum unfolded protein response. Nat Struct Mol Biol 17, 924-925.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 924-925
-
-
Onn, A.1
Ron, D.2
-
3
-
-
71749110928
-
Targeting the endoplasmic reticulum-stress response as an anticancer strategy
-
Healy SJ, Gorman AM, Mousavi-Shafaei P, Gupta S, and Samali A (2009). Targeting the endoplasmic reticulum-stress response as an anticancer strategy. Eur J Pharmacol 625, 234-246.
-
(2009)
Eur J Pharmacol
, vol.625
, pp. 234-246
-
-
Healy, S.J.1
Gorman, A.M.2
Mousavi-Shafaei, P.3
Gupta, S.4
Samali, A.5
-
4
-
-
10344222124
-
The role of the unfolded protein response in tumour development: Friend or foe?
-
Ma Y and Hendershot LM (2004). The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 4, 966-977.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
5
-
-
33947402280
-
The unfolded protein response and cancer: A brighter future unfolding?
-
Scriven P, Brown NJ, Pockley AG, and Wyld L (2007). The unfolded protein response and cancer: a brighter future unfolding? J Mol Med 85, 331-341.
-
(2007)
J Mol Med
, vol.85
, pp. 331-341
-
-
Scriven, P.1
Brown, N.J.2
Pockley, A.G.3
Wyld, L.4
-
6
-
-
32944457371
-
Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values
-
Luk JM, Lam CT, Siu AF, Lam BY, Ng IO, Hu MY, Che CM, and Fan ST (2006). Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values. Proteomics 6, 1049-1057.
-
(2006)
Proteomics
, vol.6
, pp. 1049-1057
-
-
Luk, J.M.1
Lam, C.T.2
Siu, A.F.3
Lam, B.Y.4
Ng, I.O.5
Hu, M.Y.6
Che, C.M.7
Fan, S.T.8
-
7
-
-
0038216621
-
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: A possible involvement of the ER stress pathway in hepatocarcinogenesis
-
Shuda M, Kondoh N, Imazeki N, Tanaka K, Okada T, Mori K, Hada A, Arai M, Wakatsuki T, Matsubara O, et al. (2003). Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis. J Hepatol 38, 605-614.
-
(2003)
J Hepatol
, vol.38
, pp. 605-614
-
-
Shuda, M.1
Kondoh, N.2
Imazeki, N.3
Tanaka, K.4
Okada, T.5
Mori, K.6
Hada, A.7
Arai, M.8
Wakatsuki, T.9
Matsubara, O.10
-
8
-
-
77955433925
-
Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma
-
Al-Rawashdeh FY, Scriven P, Cameron IC, Vergani PV, and Wyld L (2010). Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma. Eur J Gastroenterol Hepatol 22, 1099-1105.
-
(2010)
Eur J Gastroenterol Hepatol
, vol.22
, pp. 1099-1105
-
-
Al-Rawashdeh, F.Y.1
Scriven, P.2
Cameron, I.C.3
Vergani, P.V.4
Wyld, L.5
-
9
-
-
0033978257
-
Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas
-
Higashitsuji H, Itoh K, Nagao T, Dawson S, Nonoguchi K, Kido T, Mayer RJ, Arii S, and Fujita J (2000). Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas. Nat Med 6, 96-99.
-
(2000)
Nat Med
, vol.6
, pp. 96-99
-
-
Higashitsuji, H.1
Itoh, K.2
Nagao, T.3
Dawson, S.4
Nonoguchi, K.5
Kido, T.6
Mayer, R.J.7
Arii, S.8
Fujita, J.9
-
10
-
-
20444498521
-
Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma
-
Li H, Fu X, Chen Y, Hong Y, Tan Y, Cao H, Wu M, and Wang H (2005). Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma. Gastroenterology 128, 2029-2041.
-
(2005)
Gastroenterology
, vol.128
, pp. 2029-2041
-
-
Li, H.1
Fu, X.2
Chen, Y.3
Hong, Y.4
Tan, Y.5
Cao, H.6
Wu, M.7
Wang, H.8
-
11
-
-
70449528744
-
p28GANK inhibits endoplasmic reticulum stress-induced Neoplasia Vol. 13, No. 7, 2011 Modulation of Unfolded Protein Response of miR-122 Yang et al. 599 cell death via enhancement of the endoplasmic reticulum adaptive capacity
-
Dai RY, Chen Y, Fu J, Dong LW, Ren YB, Yang GZ, Qian YW, Cao J, Tang SH, Yang SL, et al. (2009). p28GANK inhibits endoplasmic reticulum stress-induced Neoplasia Vol. 13, No. 7, 2011 Modulation of Unfolded Protein Response of miR-122 Yang et al. 599 cell death via enhancement of the endoplasmic reticulum adaptive capacity. Cell Res 19, 1243-1257.
-
(2009)
Cell Res
, vol.19
, pp. 1243-1257
-
-
Dai, R.Y.1
Chen, Y.2
Fu, J.3
Dong, L.W.4
Ren, Y.B.5
Yang, G.Z.6
Qian, Y.W.7
Cao, J.8
Tang, S.H.9
Yang, S.L.10
-
12
-
-
0037423845
-
Vertebrate microRNA genes
-
Lim LP, Glasner ME, Yekta S, Burge CB, and Bartel DP (2003). Vertebrate microRNA genes. Science 299, 1540.
-
(2003)
Science
, vol.299
, Issue.1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
13
-
-
75749145045
-
MicroRNAs of the immune system: Roles in inflammation and cancer
-
Davidson-Moncada J, Papavasiliou FN, and Tam W (2010). MicroRNAs of the immune system: roles in inflammation and cancer. Ann N Y Acad Sci 1183, 183-194.
-
(2010)
Ann N Y Acad Sci
, vol.1183
, pp. 183-194
-
-
Davidson-Moncada, J.1
Papavasiliou, F.N.2
Tam, W.3
-
14
-
-
76649105418
-
MicroRNA function in cancer: Oncogene or a tumor suppressor?
-
Shenouda SK and Alahari SK (2009). MicroRNA function in cancer: oncogene or a tumor suppressor? Cancer Metastasis Rev 28, 369-378.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 369-378
-
-
Shenouda, S.K.1
Alahari, S.K.2
-
15
-
-
0037197803
-
Identification of tissue-specific microRNAs from mouse
-
Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, and Tuschl T (2002). Identification of tissue-specific microRNAs from mouse. Curr Biol 12, 735-739.
-
(2002)
Curr Biol
, vol.12
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
16
-
-
77957954445
-
Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development
-
Xu H, He JH, Xiao ZD, Zhang QQ, Chen YQ, Zhou H, and Qu LH (2010). Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development. Hepatology 52, 1431-1442.
-
(2010)
Hepatology
, vol.52
, pp. 1431-1442
-
-
Xu, H.1
He, J.H.2
Xiao, Z.D.3
Zhang, Q.Q.4
Chen, Y.Q.5
Zhou, H.6
Qu, L.H.7
-
17
-
-
39849108178
-
MiR-122, a paradigm for the role of microRNAs in the liver
-
Girard M, Jacquemin E, Munnich A, Lyonnet S, and Henrion-Caude A (2008). miR-122, a paradigm for the role of microRNAs in the liver. J Hepatol 48, 648-656.
-
(2008)
J Hepatol
, vol.48
, pp. 648-656
-
-
Girard, M.1
Jacquemin, E.2
Munnich, A.3
Lyonnet, S.4
Henrion-Caude, A.5
-
18
-
-
33749479908
-
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
-
Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, and Ghoshal K (2006). Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem 99, 671-678.
-
(2006)
J Cell Biochem
, vol.99
, pp. 671-678
-
-
Kutay, H.1
Bai, S.2
Datta, J.3
Motiwala, T.4
Pogribny, I.5
Frankel, W.6
Jacob, S.T.7
Ghoshal, K.8
-
19
-
-
66149114383
-
MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma
-
Tsai WC, Hsu PW, Lai TC, Chau GY, Lin CW, Chen CM, Lin CD, Liao YL, Wang JL, Chau YP, et al. (2009). MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma. Hepatology 49, 1571-1582.
-
(2009)
Hepatology
, vol.49
, pp. 1571-1582
-
-
Tsai, W.C.1
Hsu, P.W.2
Lai, T.C.3
Chau, G.Y.4
Lin, C.W.5
Chen, C.M.6
Lin, C.D.7
Liao, Y.L.8
Wang, J.L.9
Chau, Y.P.10
-
20
-
-
70349976819
-
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
-
Coulouarn C, Factor VM, Andersen JB, Durkin ME, and Thorgeirsson SS (2009). Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene 28, 3526-3536.
-
(2009)
Oncogene
, vol.28
, pp. 3526-3536
-
-
Coulouarn, C.1
Factor, V.M.2
Andersen, J.B.3
Durkin, M.E.4
Thorgeirsson, S.S.5
-
21
-
-
78049506983
-
A novel GSK-3 ß-C/EBP a-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma
-
Zeng C, Wang R, Li D, Lin XJ, Wei QK, Yuan Y, Wang Q, Chen W, and Zhuang SM (2010). A novel GSK-3 ß-C/EBP a-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma. Hepatology 52, 1702-1712.
-
(2010)
Hepatology
, vol.52
, pp. 1702-1712
-
-
Zeng, C.1
Wang, R.2
Li, D.3
Lin, X.J.4
Wei, Q.K.5
Yuan, Y.6
Wang, Q.7
Chen, W.8
Zhuang, S.M.9
-
22
-
-
70450285075
-
MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
-
Bai S, Nasser MW, Wang B, Hsu SH, Datta J, Kutay H, Yadav A, Nuovo G, Kumar P, and Ghoshal K (2009). MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J Biol Chem 284, 32015-32027.
-
(2009)
J Biol Chem
, vol.284
, pp. 32015-32027
-
-
Bai, S.1
Nasser, M.W.2
Wang, B.3
Hsu, S.H.4
Datta, J.5
Kutay, H.6
Yadav, A.7
Nuovo, G.8
Kumar, P.9
Ghoshal, K.10
-
23
-
-
67651007766
-
MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells
-
Fornari F, Gramantieri L, Giovannini C, Veronese A, Ferracin M, Sabbioni S, Calin GA, Grazi GL, Croce CM, Tavolari S, et al. (2009). miR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res 69 5761-5767.
-
Cancer Res
, vol.69
, pp. 5761-5767
-
-
Fornari, F.1
Gramantieri, L.2
Giovannini, C.3
Veronese, A.4
Ferracin, M.5
Sabbioni, S.6
Calin, G.A.7
Grazi, G.L.8
Croce, C.M.9
Tavolari, S.10
-
24
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villen J, Shin C, Camargo FD, Gygi SP, and Bartel DP (2008). The impact of microRNAs on protein output. Nature 455, 64-71.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
25
-
-
77951491943
-
MiR-17-5p promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway
-
Yang F, Yin Y, Wang F, Wang Y, Zhang L, Tang Y, and Sun S (2010). miR-17-5p promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway. Hepatology 51, 1614-1623.
-
(2010)
Hepatology
, vol.51
, pp. 1614-1623
-
-
Yang, F.1
Yin, Y.2
Wang, F.3
Wang, Y.4
Zhang, L.5
Tang, Y.6
Sun, S.7
-
26
-
-
33744973775
-
Relief of microRNA-mediated translational repression in human cells subjected to stress
-
Bhattacharyya SN, Habermacher R, Martine U, Closs EI, and Filipowicz W (2006). Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125, 1111-1124.
-
(2006)
Cell
, vol.125
, pp. 1111-1124
-
-
Bhattacharyya, S.N.1
Habermacher, R.2
Martine, U.3
Closs, E.I.4
Filipowicz, W.5
-
27
-
-
36348943088
-
Integrated endoplasmic reticulum stress responses in cancer
-
Moenner M, Pluquet O, Bouchecareilh M, and Chevet E (2007). Integrated endoplasmic reticulum stress responses in cancer. Cancer Res 67, 10631-10634.
-
(2007)
Cancer Res
, vol.67
, pp. 10631-10634
-
-
Moenner, M.1
Pluquet, O.2
Bouchecareilh, M.3
Chevet, E.4
-
28
-
-
73649145525
-
An altered pattern of liver apolipoprotein A-I isoforms is implicated in male chronic hepatitis B progression
-
Yang F, Yin Y, Wang F, Zhang L, Wang Y, and Sun S (2010). An altered pattern of liver apolipoprotein A-I isoforms is implicated in male chronic hepatitis B progression. J Proteome Res 9, 134-143.
-
(2010)
J Proteome Res
, vol.9
, pp. 134-143
-
-
Yang, F.1
Yin, Y.2
Wang, F.3
Zhang, L.4
Wang, Y.5
Sun, S.6
-
29
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, and Rajewsky N (2008). Widespread changes in protein synthesis induced by microRNAs. Nature 455, 58-63.
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
30
-
-
77956249298
-
MicroRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma
-
Burchard J, Zhang C, Liu AM, Poon RT, Lee NP, Wong KF, Sham PC, Lam BY, Ferguson MD, Tokiwa G, et al. (2010). microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma. Mol Syst Biol 6, 402.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 402
-
-
Burchard, J.1
Zhang, C.2
Liu, A.M.3
Poon, R.T.4
Lee, N.P.5
Wong, K.F.6
Sham, P.C.7
Lam, B.Y.8
Ferguson, M.D.9
Tokiwa, G.10
-
31
-
-
58549109007
-
Potent inhibition of microRNA in vivo without degradation
-
Davis S, Propp S, Freier SM, Jones LE, Serra MJ, Kinberger G, Bhat B, Swayze EE, Bennett CF, and Esau C (2009). Potent inhibition of microRNA in vivo without degradation. Nucleic Acids Res 37, 70-77.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 70-77
-
-
Davis, S.1
Propp, S.2
Freier, S.M.3
Jones, L.E.4
Serra, M.J.5
Kinberger, G.6
Bhat, B.7
Swayze, E.E.8
Bennett, C.F.9
Esau, C.10
-
32
-
-
49549111852
-
Proteomics joins the search for micro- RNA targets
-
Grosshans H and Filipowicz W (2008). Proteomics joins the search for micro- RNA targets. Cell 134, 560-562.
-
(2008)
Cell
, vol.134
, pp. 560-562
-
-
Grosshans, H.1
Filipowicz, W.2
-
33
-
-
33645080188
-
Beyond lectins: The calnexin/calreticulin chaperone system of the endoplasmic reticulum
-
Williams DB (2006). Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum. J Cell Sci 119, 615-623.
-
(2006)
J Cell Sci
, vol.119
, pp. 615-623
-
-
Williams, D.B.1
-
34
-
-
9144252641
-
Purification and biochemical characterization of native ERp29 from rat liver
-
Hubbard MJ, Mangum JE, and McHugh NJ (2004). Purification and biochemical characterization of native ERp29 from rat liver. Biochem J 383, 589-597.
-
(2004)
Biochem J
, vol.383
, pp. 589-597
-
-
Hubbard, M.J.1
Mangum, J.E.2
McHugh, N.J.3
-
35
-
-
33747368704
-
PP2A regulates BCL-2 phosphorylation and proteasomemediated degradation at the endoplasmic reticulum
-
Lin SS, Bassik MC, Suh H, Nishino M, Arroyo JD, Hahn WC, Korsmeyer SJ, and Roberts TM (2006). PP2A regulates BCL-2 phosphorylation and proteasomemediated degradation at the endoplasmic reticulum. J Biol Chem 281, 23003-23012.
-
(2006)
J Biol Chem
, vol.281
, pp. 23003-23012
-
-
Lin, S.S.1
Bassik, M.C.2
Suh, H.3
Nishino, M.4
Arroyo, J.D.5
Hahn, W.C.6
Korsmeyer, S.J.7
Roberts, T.M.8
-
36
-
-
31444449462
-
Role of the unfolded protein response in cell death
-
Kim R, Emi M, Tanabe K, and Murakami S (2006). Role of the unfolded protein response in cell death. Apoptosis 11, 5-13.
-
(2006)
Apoptosis
, vol.11
, pp. 5-13
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
Murakami, S.4
-
37
-
-
0038080911
-
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation
-
Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, and Lee AS (2003). Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J Biol Chem 278, 20915-20924.
-
(2003)
J Biol Chem
, vol.278
, pp. 20915-20924
-
-
Reddy, R.K.1
Mao, C.2
Baumeister, P.3
Austin, R.C.4
Kaufman, R.J.5
Lee, A.S.6
|