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Volumn 108, Issue 3, 2013, Pages 357-361

Molecular radiation biology/oncology at its best: Cutting edge research presented at the 13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ATM PROTEIN; BIOLOGICAL MARKER; CHEMOKINE RECEPTOR CXCR4; CHLOROQUINE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; MICRORNA; MIRNA 335; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

EID: 84887004029     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.10.001     Document Type: Editorial
Times cited : (5)

References (130)
  • 1
    • 79960379461 scopus 로고    scopus 로고
    • Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access
    • K. Dittmann, C. Mayer, and B. Fehrenbacher Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access Radiother Oncol 99 2011 317 322
    • (2011) Radiother Oncol , vol.99 , pp. 317-322
    • Dittmann, K.1    Mayer, C.2    Fehrenbacher, B.3
  • 2
    • 79960341728 scopus 로고    scopus 로고
    • Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures
    • I. Eke, and N. Cordes Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures Radiother Oncol 99 2011 279 286
    • (2011) Radiother Oncol , vol.99 , pp. 279-286
    • Eke, I.1    Cordes, N.2
  • 3
    • 79960352442 scopus 로고    scopus 로고
    • Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression
    • K. Gurtner, Y. Deuse, and R. Butof Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression Radiother Oncol 99 2011 323 330
    • (2011) Radiother Oncol , vol.99 , pp. 323-330
    • Gurtner, K.1    Deuse, Y.2    Butof, R.3
  • 4
    • 80051685792 scopus 로고    scopus 로고
    • Phosphorylation of EGFR measured with in situ proximity ligation assay: Relationship to EGFR protein level and gene dosage in cervical cancer
    • C. Halle, M. Lando, and K. Sundfor Phosphorylation of EGFR measured with in situ proximity ligation assay: relationship to EGFR protein level and gene dosage in cervical cancer Radiother Oncol 101 2011 152 157
    • (2011) Radiother Oncol , vol.101 , pp. 152-157
    • Halle, C.1    Lando, M.2    Sundfor, K.3
  • 5
    • 84887023636 scopus 로고    scopus 로고
    • EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival
    • [epub ahead of print]
    • B. Jutten, T.G. Keulers, and M.B. Schaaf EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival Radiother Oncol 2013 [epub ahead of print]
    • (2013) Radiother Oncol
    • Jutten, B.1    Keulers, T.G.2    Schaaf, M.B.3
  • 6
    • 80655127846 scopus 로고    scopus 로고
    • In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status
    • L. Myllynen, T. Rieckmann, and J. Dahm-Daphi In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status Radiother Oncol 101 2011 147 151
    • (2011) Radiother Oncol , vol.101 , pp. 147-151
    • Myllynen, L.1    Rieckmann, T.2    Dahm-Daphi, J.3
  • 7
    • 80655124677 scopus 로고    scopus 로고
    • Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation
    • M. Toulany, T.A. Schickfluss, and K.R. Fattah Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation Radiother Oncol 101 2011 140 146
    • (2011) Radiother Oncol , vol.101 , pp. 140-146
    • Toulany, M.1    Schickfluss, T.A.2    Fattah, K.R.3
  • 8
    • 84864018780 scopus 로고    scopus 로고
    • Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair
    • M. Toulany, K.J. Lee, and K.R. Fattah Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair Mol Cancer Res 10 2012 945 957
    • (2012) Mol Cancer Res , vol.10 , pp. 945-957
    • Toulany, M.1    Lee, K.J.2    Fattah, K.R.3
  • 9
    • 77955277480 scopus 로고    scopus 로고
    • The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining
    • M. Kriegs, U. Kasten-Pisula, and T. Rieckmann The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining DNA Repair 9 2010 889 897
    • (2010) DNA Repair , vol.9 , pp. 889-897
    • Kriegs, M.1    Kasten-Pisula, U.2    Rieckmann, T.3
  • 10
    • 84887019478 scopus 로고    scopus 로고
    • Acquired resistance to cetuximab is associated with the overexpression of Ras family members and the loss of radiosensitization in head and neck cancer cells
    • M. Saki, M. Toulany, and H.P. Rodemann Acquired resistance to cetuximab is associated with the overexpression of Ras family members and the loss of radiosensitization in head and neck cancer cells Radiother Oncol 108 2013 473 478
    • (2013) Radiother Oncol , vol.108 , pp. 473-478
    • Saki, M.1    Toulany, M.2    Rodemann, H.P.3
  • 11
    • 80655127826 scopus 로고    scopus 로고
    • The role of homologous recombination in radiation-induced double-strand break repair
    • P.A. Jeggo, V. Geuting, and M. Lobrich The role of homologous recombination in radiation-induced double-strand break repair Radiother Oncol 101 2011 7 12
    • (2011) Radiother Oncol , vol.101 , pp. 7-12
    • Jeggo, P.A.1    Geuting, V.2    Lobrich, M.3
  • 12
    • 80655127832 scopus 로고    scopus 로고
    • Assessing 'radiosensitivity' with kinetic profiles of gamma-H2AX, 53BP1 and BRCA1 foci
    • N.T. Martin, S.A. Nahas, and R. Tunuguntla Assessing 'radiosensitivity' with kinetic profiles of gamma-H2AX, 53BP1 and BRCA1 foci Radiother Oncol 101 2011 35 38
    • (2011) Radiother Oncol , vol.101 , pp. 35-38
    • Martin, N.T.1    Nahas, S.A.2    Tunuguntla, R.3
  • 13
    • 80655127835 scopus 로고    scopus 로고
    • Retention of gammaH2AX foci as an indication of lethal DNA damage
    • P.L. Olive Retention of gammaH2AX foci as an indication of lethal DNA damage Radiother Oncol 101 2011 18 23
    • (2011) Radiother Oncol , vol.101 , pp. 18-23
    • Olive, P.L.1
  • 14
    • 84857910490 scopus 로고    scopus 로고
    • DNA damage by X-rays and their impact on replication processes
    • A.C. Parplys, E. Petermann, and C. Petersen DNA damage by X-rays and their impact on replication processes Radiother Oncol 102 2012 466 471
    • (2012) Radiother Oncol , vol.102 , pp. 466-471
    • Parplys, A.C.1    Petermann, E.2    Petersen, C.3
  • 15
    • 5144225797 scopus 로고    scopus 로고
    • DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining
    • J. Bentley, C.P. Diggle, and P. Harnden DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining Nucleic Acids Res 32 2004 5249 5259
    • (2004) Nucleic Acids Res , vol.32 , pp. 5249-5259
    • Bentley, J.1    Diggle, C.P.2    Harnden, P.3
  • 16
    • 84856021931 scopus 로고    scopus 로고
    • Targeting abnormal DNA repair in therapy-resistant breast cancers
    • L.A. Tobin, C. Robert, and P. Nagaria Targeting abnormal DNA repair in therapy-resistant breast cancers Mol Cancer Res 10 2012 96 107
    • (2012) Mol Cancer Res , vol.10 , pp. 96-107
    • Tobin, L.A.1    Robert, C.2    Nagaria, P.3
  • 17
    • 84884544457 scopus 로고    scopus 로고
    • Estrogen Receptor alpha Regulates ATM Expression through miRNAs in Breast Cancer
    • [epub ahead of print]
    • X. Guo, C. Yang, and X. Qian Estrogen Receptor alpha Regulates ATM Expression through miRNAs in Breast Cancer Clin Cancer Res 2013 [epub ahead of print]
    • (2013) Clin Cancer Res
    • Guo, X.1    Yang, C.2    Qian, X.3
  • 18
    • 84887022070 scopus 로고    scopus 로고
    • ATM-mediated Snail Serine 100 phosphorylation regulates cellular radiosensitivity
    • R.J. Boohaker, X. Cui, and M. Stackhouse ATM-mediated Snail Serine 100 phosphorylation regulates cellular radiosensitivity Radiother Oncol 108 2013 403 408
    • (2013) Radiother Oncol , vol.108 , pp. 403-408
    • Boohaker, R.J.1    Cui, X.2    Stackhouse, M.3
  • 19
    • 84859004905 scopus 로고    scopus 로고
    • Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions
    • N. Tomimatsu, B. Mukherjee, and K. Deland Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions DNA Repair 11 2012 441 448
    • (2012) DNA Repair , vol.11 , pp. 441-448
    • Tomimatsu, N.1    Mukherjee, B.2    Deland, K.3
  • 20
    • 84876122536 scopus 로고    scopus 로고
    • Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
    • M. Lando, S.M. Wilting, and K. Snipstad Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling J Pathol 230 2013 59 69
    • (2013) J Pathol , vol.230 , pp. 59-69
    • Lando, M.1    Wilting, S.M.2    Snipstad, K.3
  • 21
    • 34250201533 scopus 로고    scopus 로고
    • Expression of EGFR variant vIII promotes both radiation resistance and hypoxia tolerance
    • S.A. Weppler, Y. Li, and L. Dubois Expression of EGFR variant vIII promotes both radiation resistance and hypoxia tolerance Radiother Oncol 83 2007 333 339
    • (2007) Radiother Oncol , vol.83 , pp. 333-339
    • Weppler, S.A.1    Li, Y.2    Dubois, L.3
  • 22
    • 79960356284 scopus 로고    scopus 로고
    • Autophagy contributes to resistance of tumor cells to ionizing radiation
    • H. Chaachouay, P. Ohneseit, and M. Toulany Autophagy contributes to resistance of tumor cells to ionizing radiation Radiother Oncol 99 2011 287 292
    • (2011) Radiother Oncol , vol.99 , pp. 287-292
    • Chaachouay, H.1    Ohneseit, P.2    Toulany, M.3
  • 23
    • 40449086885 scopus 로고    scopus 로고
    • Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
    • A. Apel, I. Herr, and H. Schwarz Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy Cancer Res 68 2008 1485 1494
    • (2008) Cancer Res , vol.68 , pp. 1485-1494
    • Apel, A.1    Herr, I.2    Schwarz, H.3
  • 24
    • 84887015356 scopus 로고    scopus 로고
    • Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up
    • J. Vignard, G. Mirey, and B. Salles Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up Radiother Oncol 108 2013 362 369
    • (2013) Radiother Oncol , vol.108 , pp. 362-369
    • Vignard, J.1    Mirey, G.2    Salles, B.3
  • 25
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • E.P. Rogakou, D.R. Pilch, and A.H. Orr DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J Biol Chem 273 1998 5858 5868
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3
  • 26
    • 79958109315 scopus 로고    scopus 로고
    • A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia
    • F. Bouquet, M. Ousset, and D. Biard A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia J Cell Sci 124 2011 1943 1951
    • (2011) J Cell Sci , vol.124 , pp. 1943-1951
    • Bouquet, F.1    Ousset, M.2    Biard, D.3
  • 27
    • 84870587195 scopus 로고    scopus 로고
    • The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage
    • P. Reynolds, J.A. Anderson, and J.V. Harper The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage Nucleic Acids Res 40 2012 10821 10831
    • (2012) Nucleic Acids Res , vol.40 , pp. 10821-10831
    • Reynolds, P.1    Anderson, J.A.2    Harper, J.V.3
  • 28
    • 80052168685 scopus 로고    scopus 로고
    • The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
    • T. Helleday The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings Mol Oncol 5 2011 387 393
    • (2011) Mol Oncol , vol.5 , pp. 387-393
    • Helleday, T.1
  • 29
    • 84880537027 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibitors as cancer therapy
    • J.F. Hilton, M.J. Hadfield, and M.T. Tran Poly(ADP-ribose) polymerase inhibitors as cancer therapy Front Biosci 18 2013 1392 1406
    • (2013) Front Biosci , vol.18 , pp. 1392-1406
    • Hilton, J.F.1    Hadfield, M.J.2    Tran, M.T.3
  • 31
    • 77956487620 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets
    • A.J. Chalmers, M. Lakshman, and N. Chan Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets Semin Radiat Oncol 20 2010 274 281
    • (2010) Semin Radiat Oncol , vol.20 , pp. 274-281
    • Chalmers, A.J.1    Lakshman, M.2    Chan, N.3
  • 32
    • 80755187806 scopus 로고    scopus 로고
    • Double-strand break end resection and repair pathway choice
    • L.S. Symington, and J. Gautier Double-strand break end resection and repair pathway choice Annu Rev Genet 45 2011 247 271
    • (2011) Annu Rev Genet , vol.45 , pp. 247-271
    • Symington, L.S.1    Gautier, J.2
  • 33
    • 84883509448 scopus 로고    scopus 로고
    • Controlling DNA-end resection: A new task for CDKs
    • L.P. Ferretti, L. Lafranchi, and A.A. Sartori Controlling DNA-end resection: a new task for CDKs Front Genet 4 2013 99
    • (2013) Front Genet , vol.4 , pp. 99
    • Ferretti, L.P.1    Lafranchi, L.2    Sartori, A.A.3
  • 34
    • 76549127430 scopus 로고    scopus 로고
    • ATM is down-regulated by N-Myc-regulated microRNA-421
    • H. Hu, L. Du, and G. Nagabayashi ATM is down-regulated by N-Myc-regulated microRNA-421 Proc Natl Acad Sci USA 107 2010 1506 1511
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1506-1511
    • Hu, H.1    Du, L.2    Nagabayashi, G.3
  • 35
    • 84874654073 scopus 로고    scopus 로고
    • Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma
    • W.Y. Mansour, N.V. Bogdanova, and U. Kasten-Pisula Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma Radiother Oncol 106 2013 147 154
    • (2013) Radiother Oncol , vol.106 , pp. 147-154
    • Mansour, W.Y.1    Bogdanova, N.V.2    Kasten-Pisula, U.3
  • 36
    • 84878505440 scopus 로고    scopus 로고
    • ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response
    • N.T. Martin, K. Nakamura, and R. Davies ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response PLoS Genet 9 2013 e1003505
    • (2013) PLoS Genet , vol.9 , pp. 1003505
    • Martin, N.T.1    Nakamura, K.2    Davies, R.3
  • 37
    • 44449118949 scopus 로고    scopus 로고
    • Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
    • D.J. Richard, E. Bolderson, and L. Cubeddu Single-stranded DNA-binding protein hSSB1 is critical for genomic stability Nature 453 2008 677 681
    • (2008) Nature , vol.453 , pp. 677-681
    • Richard, D.J.1    Bolderson, E.2    Cubeddu, L.3
  • 38
    • 84874784421 scopus 로고    scopus 로고
    • Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2
    • W. Shi, A.L. Bain, and B. Schwer Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2 PLoS Genet 9 2013 e1003298
    • (2013) PLoS Genet , vol.9 , pp. 1003298
    • Shi, W.1    Bain, A.L.2    Schwer, B.3
  • 39
    • 77953810074 scopus 로고    scopus 로고
    • Cancer stem cells at the crossroads of current cancer therapy failures-radiation oncology perspective
    • U. Koch, M. Krause, and M. Baumann Cancer stem cells at the crossroads of current cancer therapy failures-radiation oncology perspective Semin Cancer Biol 20 2010 116 124
    • (2010) Semin Cancer Biol , vol.20 , pp. 116-124
    • Koch, U.1    Krause, M.2    Baumann, M.3
  • 40
    • 84887014918 scopus 로고    scopus 로고
    • Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g
    • J. Salendo, M. Spitzner, and F. Kramer Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g Radiother Oncol 108 2013 451 457
    • (2013) Radiother Oncol , vol.108 , pp. 451-457
    • Salendo, J.1    Spitzner, M.2    Kramer, F.3
  • 41
    • 84887021060 scopus 로고    scopus 로고
    • Osteopontin and splice variant expression level in human malignant glioma: Radiobiologic effects and prognosis after radiotherapy
    • A. Güttler, M. Giebler, and P. Cuno Osteopontin and splice variant expression level in human malignant glioma: radiobiologic effects and prognosis after radiotherapy Radiother Oncol 108 2013 535 540
    • (2013) Radiother Oncol , vol.108 , pp. 535-540
    • Güttler, A.1    Giebler, M.2    Cuno, P.3
  • 42
    • 84884580486 scopus 로고    scopus 로고
    • TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: Implications for fusion status and DSB repair
    • [in press]
    • A. DalPra, E. Lalonde, and J. Sykes TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair Clin Cancer Res 2013 [in press]
    • (2013) Clin Cancer Res
    • Dalpra, A.1    Lalonde, E.2    Sykes, J.3
  • 43
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells
    • M.F. Clarke, J.E. Dick, and P.B. Dirks Cancer stem cells-perspectives on current status and future directions: AACR Workshop on cancer stem cells Cancer Res 66 2006 9339 9344
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3
  • 44
    • 45849089879 scopus 로고    scopus 로고
    • Exploring the role of cancer stem cells in radioresistance
    • M. Baumann, M. Krause, and R. Hill Exploring the role of cancer stem cells in radioresistance Nat Rev Cancer 8 2008 545 554
    • (2008) Nat Rev Cancer , vol.8 , pp. 545-554
    • Baumann, M.1    Krause, M.2    Hill, R.3
  • 45
    • 33845981049 scopus 로고    scopus 로고
    • Successful therapy must eradicate cancer stem cells
    • D. Dingli, and F. Michor Successful therapy must eradicate cancer stem cells Stem Cells 24 2006 2603 2610
    • (2006) Stem Cells , vol.24 , pp. 2603-2610
    • Dingli, D.1    Michor, F.2
  • 47
    • 84887025650 scopus 로고    scopus 로고
    • Clinical perspectives of cancer stem cell research in radiation oncology
    • [in press]
    • R. Bütof, A. Dubrovska, and M. Baumann Clinical perspectives of cancer stem cell research in radiation oncology Radiother Oncol 2013 [in press]
    • (2013) Radiother Oncol
    • Bütof, R.1    Dubrovska, A.2    Baumann, M.3
  • 50
    • 79960348627 scopus 로고    scopus 로고
    • Selection of radioresistant tumor cells and presence of ALDH1 activity in vitro
    • J. Mihatsch, M. Toulany, and P.M. Bareiss Selection of radioresistant tumor cells and presence of ALDH1 activity in vitro Radiother Oncol 99 2011 300 306
    • (2011) Radiother Oncol , vol.99 , pp. 300-306
    • Mihatsch, J.1    Toulany, M.2    Bareiss, P.M.3
  • 51
    • 79960346496 scopus 로고    scopus 로고
    • Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance
    • F.P. D'Andrea, A. Safwat, M. Kassem, L. Gautier, J. Overgaard, and M.R. Horsman Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance Radiother Oncol 99 2011 373 378
    • (2011) Radiother Oncol , vol.99 , pp. 373-378
    • D'Andrea, F.P.1    Safwat, A.2    Kassem, M.3    Gautier, L.4    Overgaard, J.5    Horsman, M.R.6
  • 52
    • 84871326346 scopus 로고    scopus 로고
    • Coxsackie-adenovirus receptor as a novel marker of stem cells in treatment-resistant non-small cell lung cancer
    • X. Zhang, B. Fang, R. Mohan, and J.Y. Chang Coxsackie-adenovirus receptor as a novel marker of stem cells in treatment-resistant non-small cell lung cancer Radiother Oncol 105 2012 250 257
    • (2012) Radiother Oncol , vol.105 , pp. 250-257
    • Zhang, X.1    Fang, B.2    Mohan, R.3    Chang, J.Y.4
  • 53
    • 80655149141 scopus 로고    scopus 로고
    • Radioresistant head and neck squamous cell carcinoma cells: Intracellular signaling, putative biomarkers for tumor recurrences and possible therapeutic targets
    • S. Skvortsov, C.R. Jimenez, and J.C. Knol Radioresistant head and neck squamous cell carcinoma cells: intracellular signaling, putative biomarkers for tumor recurrences and possible therapeutic targets Radiother Oncol 101 2011 177 182
    • (2011) Radiother Oncol , vol.101 , pp. 177-182
    • Skvortsov, S.1    Jimenez, C.R.2    Knol, J.C.3
  • 54
    • 84881474210 scopus 로고    scopus 로고
    • Prediction of response to radiotherapy in the treatment of esophageal cancer using stem cell markers
    • J.K. Smit, H. Faber, and M. Niemantsverdriet Prediction of response to radiotherapy in the treatment of esophageal cancer using stem cell markers Radiother Oncol 107 2013 434 441
    • (2013) Radiother Oncol , vol.107 , pp. 434-441
    • Smit, J.K.1    Faber, H.2    Niemantsverdriet, M.3
  • 55
    • 84873566048 scopus 로고    scopus 로고
    • The roots of cancer: Stem cells and the basis for tumor heterogeneity
    • M. Shibata, and M.M. Shen The roots of cancer: stem cells and the basis for tumor heterogeneity Bioessays 35 2013 253 260
    • (2013) Bioessays , vol.35 , pp. 253-260
    • Shibata, M.1    Shen, M.M.2
  • 56
    • 79953766940 scopus 로고    scopus 로고
    • Tumour evolution inferred by single-cell sequencing
    • N. Navin, J. Kendall, and J. Troge Tumour evolution inferred by single-cell sequencing Nature 472 2011 90 94
    • (2011) Nature , vol.472 , pp. 90-94
    • Navin, N.1    Kendall, J.2    Troge, J.3
  • 57
    • 84874598318 scopus 로고    scopus 로고
    • Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
    • A. Sottoriva, I. Spiteri, and S.G. Piccirillo Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics Proc Natl Acad Sci USA 110 2013 4009 4014
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 4009-4014
    • Sottoriva, A.1    Spiteri, I.2    Piccirillo, S.G.3
  • 58
    • 84871968042 scopus 로고    scopus 로고
    • Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization
    • A. Sottoriva, I. Spiteri, D. Shibata, C. Curtis, and S. Tavare Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization Cancer Res 73 2013 41 49
    • (2013) Cancer Res , vol.73 , pp. 41-49
    • Sottoriva, A.1    Spiteri, I.2    Shibata, D.3    Curtis, C.4    Tavare, S.5
  • 59
    • 84865720928 scopus 로고    scopus 로고
    • Long term results of a prospective dose escalation phase-II trial: Interstitial pulsed-dose-rate brachytherapy as boost for intermediate- and high-risk prostate cancer
    • S. Lettmaier, M. Lotter, S. Kreppner, A. Strnad, R. Fietkau, and V. Strnad Long term results of a prospective dose escalation phase-II trial: interstitial pulsed-dose-rate brachytherapy as boost for intermediate- and high-risk prostate cancer Radiother Oncol 104 2012 181 186
    • (2012) Radiother Oncol , vol.104 , pp. 181-186
    • Lettmaier, S.1    Lotter, M.2    Kreppner, S.3    Strnad, A.4    Fietkau, R.5    Strnad, V.6
  • 60
    • 84872525097 scopus 로고    scopus 로고
    • Dual targeting of EGFR and HER3 with MEHD7945A overcomes acquired resistance to EGFR inhibitors and radiation
    • S. Huang, C. Li, and E.A. Armstrong Dual targeting of EGFR and HER3 with MEHD7945A overcomes acquired resistance to EGFR inhibitors and radiation Cancer Res 73 2013 824 833
    • (2013) Cancer Res , vol.73 , pp. 824-833
    • Huang, S.1    Li, C.2    Armstrong, E.A.3
  • 61
    • 0344676392 scopus 로고    scopus 로고
    • Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes
    • C.N. Andreassen, J. Alsner, M. Overgaard, and J. Overgaard Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes Radiother Oncol 69 2003 127 135
    • (2003) Radiother Oncol , vol.69 , pp. 127-135
    • Andreassen, C.N.1    Alsner, J.2    Overgaard, M.3    Overgaard, J.4
  • 62
    • 33748577313 scopus 로고    scopus 로고
    • Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM-A study based on DNA from formalin fixed paraffin embedded tissue samples
    • C.N. Andreassen, J. Alsner, M. Overgaard, F.B. Sorensen, and J. Overgaard Risk of radiation-induced subcutaneous fibrosis in relation to single nucleotide polymorphisms in TGFB1, SOD2, XRCC1, XRCC3, APEX and ATM-a study based on DNA from formalin fixed paraffin embedded tissue samples Int J Radiat Biol 82 2006 577 586
    • (2006) Int J Radiat Biol , vol.82 , pp. 577-586
    • Andreassen, C.N.1    Alsner, J.2    Overgaard, M.3    Sorensen, F.B.4    Overgaard, J.5
  • 63
    • 31844437458 scopus 로고    scopus 로고
    • ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy
    • C.N. Andreassen, J. Overgaard, and J. Alsner ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy Int J Radiat Oncol Biol Phys 64 2006 776 783
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 776-783
    • Andreassen, C.N.1    Overgaard, J.2    Alsner, J.3
  • 64
    • 40249107534 scopus 로고    scopus 로고
    • Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis
    • O.K. Rødningen, A.L. Borresen-Dale, J. Alsner, T. Hastie, and J. Overgaard Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis Radiother Oncol 86 2008 314 320
    • (2008) Radiother Oncol , vol.86 , pp. 314-320
    • Rødningen, O.K.1    Borresen-Dale, A.L.2    Alsner, J.3    Hastie, T.4    Overgaard, J.5
  • 65
    • 34250181748 scopus 로고    scopus 로고
    • Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis
    • J. Alsner, O.K. Rødningen, and J. Overgaard Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis Radiother Oncol 83 2007 261 266
    • (2007) Radiother Oncol , vol.83 , pp. 261-266
    • Alsner, J.1    Rødningen, O.K.2    Overgaard, J.3
  • 66
    • 84887018101 scopus 로고    scopus 로고
    • Contributions of AMPK and p53 dependent signaling to radiation response in the presence of metformin
    • H. Muaddi, S. Chowdhury, R. Vellanki, P. Zamiara, and M. Koritzinsky Contributions of AMPK and p53 dependent signaling to radiation response in the presence of metformin Radiother Oncol 108 2013 446 450
    • (2013) Radiother Oncol , vol.108 , pp. 446-450
    • Muaddi, H.1    Chowdhury, S.2    Vellanki, R.3    Zamiara, P.4    Koritzinsky, M.5
  • 67
    • 84878561961 scopus 로고    scopus 로고
    • Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK
    • Y. Storozhuk, S.N. Hopmans, T. Sanli, C. Barron, E. Tsiani, and J.-C. Cutz Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK Br J Cancer 108 2013 2021 2032
    • (2013) Br J Cancer , vol.108 , pp. 2021-2032
    • Storozhuk, Y.1    Hopmans, S.N.2    Sanli, T.3    Barron, C.4    Tsiani, E.5    Cutz, J.-C.6
  • 69
    • 77955917717 scopus 로고    scopus 로고
    • Ionizing radiation activates AMP-activated kinase (AMPK): A target for radiosensitization of human cancer cells
    • T. Sanli, A. Rashid, C. Liu, S. Harding, R.G. Bristow, and J.-C. Cutz Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells Int J Radiat Oncol Biol Phys 78 2010 221 229
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 221-229
    • Sanli, T.1    Rashid, A.2    Liu, C.3    Harding, S.4    Bristow, R.G.5    Cutz, J.-C.6
  • 70
    • 84860196738 scopus 로고    scopus 로고
    • Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
    • C.W. Song, H. Lee, R.P.M. Dings, B. Williams, J. Powers, and T.D. Santos Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells Sci Rep 2 2012 362
    • (2012) Sci Rep , vol.2 , pp. 362
    • Song, C.W.1    Lee, H.2    Dings, R.P.M.3    Williams, B.4    Powers, J.5    Santos, T.D.6
  • 71
    • 84887019324 scopus 로고    scopus 로고
    • Hypoxia and metastasis in an orthotopic cervix cancer xenograft model
    • N. Chaudary, H. Mujcic, B.G. Wouters, and R.P. Hill Hypoxia and metastasis in an orthotopic cervix cancer xenograft model Radiother Oncol 108 2013 506 510
    • (2013) Radiother Oncol , vol.108 , pp. 506-510
    • Chaudary, N.1    Mujcic, H.2    Wouters, B.G.3    Hill, R.P.4
  • 73
    • 25444518176 scopus 로고    scopus 로고
    • Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer
    • H. Kanao, T. Enomoto, T. Kimura, M. Fujita, R. Nakashima, and Y. Ueda Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer Cancer Res 65 2005 8640 8645
    • (2005) Cancer Res , vol.65 , pp. 8640-8645
    • Kanao, H.1    Enomoto, T.2    Kimura, T.3    Fujita, M.4    Nakashima, R.5    Ueda, Y.6
  • 74
    • 0037279517 scopus 로고    scopus 로고
    • The hypoxic tumour microenvironment and metastatic progression
    • P. Subarsky, and R.P. Hill The hypoxic tumour microenvironment and metastatic progression Clin Exp Metastasis 20 2003 237 250
    • (2003) Clin Exp Metastasis , vol.20 , pp. 237-250
    • Subarsky, P.1    Hill, R.P.2
  • 75
    • 84887019826 scopus 로고    scopus 로고
    • New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia
    • D. Cojocari, R.N. Vellanki, B. Sit, D. Uehling, M. Koritzinsky, and B.G. Wouters New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia Radiother Oncol 108 2013 541 547
    • (2013) Radiother Oncol , vol.108 , pp. 541-547
    • Cojocari, D.1    Vellanki, R.N.2    Sit, B.3    Uehling, D.4    Koritzinsky, M.5    Wouters, B.G.6
  • 76
    • 69949115589 scopus 로고    scopus 로고
    • Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
    • H. Mujcic, T. Rzymski, K.M.A. Rouschop, M. Koritzinsky, M. Milani, and A.L. Harris Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3 Radiother Oncol 92 2009 450 459
    • (2009) Radiother Oncol , vol.92 , pp. 450-459
    • Mujcic, H.1    Rzymski, T.2    Rouschop, K.M.A.3    Koritzinsky, M.4    Milani, M.5    Harris, A.L.6
  • 77
    • 54549089738 scopus 로고    scopus 로고
    • Hypoxia signalling through mTOR and the unfolded protein response in cancer
    • B.G. Wouters, and M. Koritzinsky Hypoxia signalling through mTOR and the unfolded protein response in cancer Nat Rev Cancer 8 2008 851 864
    • (2008) Nat Rev Cancer , vol.8 , pp. 851-864
    • Wouters, B.G.1    Koritzinsky, M.2
  • 78
    • 84875234688 scopus 로고    scopus 로고
    • PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
    • K.M. Rouschop, L.J. Dubois, T.G. Keulers, T. van den Beucken, P. Lambin, and J. Bussink PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS PNAS 110 2013 4622 4627
    • (2013) PNAS , vol.110 , pp. 4622-4627
    • Rouschop, K.M.1    Dubois, L.J.2    Keulers, T.G.3    Van Den Beucken, T.4    Lambin, P.5    Bussink, J.6
  • 79
  • 82
    • 74949118681 scopus 로고    scopus 로고
    • The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
    • K.M.A. Rouschop, T. van den Beucken, L. Dubois, H. Niessen, J. Bussink, and K. Savelkouls The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 J Clin Invest 120 2010 127 141
    • (2010) J Clin Invest , vol.120 , pp. 127-141
    • Rouschop, K.M.A.1    Van Den Beucken, T.2    Dubois, L.3    Niessen, H.4    Bussink, J.5    Savelkouls, K.6
  • 84
    • 84859385707 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma
    • Y.-L. Hu, M. DeLay, A. Jahangiri, A.M. Molinaro, S.D. Rose, and W.S. Carbonell Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma Cancer Res 72 2012 1773 1783
    • (2012) Cancer Res , vol.72 , pp. 1773-1783
    • Hu, Y.-L.1    Delay, M.2    Jahangiri, A.3    Molinaro, A.M.4    Rose, S.D.5    Carbonell, W.S.6
  • 86
    • 80655144415 scopus 로고    scopus 로고
    • Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T
    • C.H.M.A. Ramaekers, T. van den Beucken, A. Meng, S. Kassam, J. Thoms, and R.G. Bristow Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T Radiother Oncol 101 2011 190 197
    • (2011) Radiother Oncol , vol.101 , pp. 190-197
    • Ramaekers, C.H.M.A.1    Van Den Beucken, T.2    Meng, A.3    Kassam, S.4    Thoms, J.5    Bristow, R.G.6
  • 87
    • 79960341240 scopus 로고    scopus 로고
    • ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells
    • S.M. Harding, C. Coackley, and R.G. Bristow ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells Radiother Oncol 99 2011 307 312
    • (2011) Radiother Oncol , vol.99 , pp. 307-312
    • Harding, S.M.1    Coackley, C.2    Bristow, R.G.3
  • 89
    • 84881048938 scopus 로고    scopus 로고
    • Dasatinib inhibits DNA Repair after radiotherapy specifically in pSFK-expressing tumor areas in head and neck xenograft tumors
    • H. Stegeman, P.N. Span, P.F.J.W. Rijken, S.C. Cockx, D.L. Wheeler, and M. Iida Dasatinib inhibits DNA Repair after radiotherapy specifically in pSFK-expressing tumor areas in head and neck xenograft tumors Transl Oncol 6 2013 413 419
    • (2013) Transl Oncol , vol.6 , pp. 413-419
    • Stegeman, H.1    Span, P.N.2    Rijken, P.F.J.W.3    Cockx, S.C.4    Wheeler, D.L.5    Iida, M.6
  • 90
    • 84883156869 scopus 로고    scopus 로고
    • Interaction of EGFR with the tumour microenvironment: Implications for radiation treatment
    • M.M. Nijkamp, P.N. Span, J. Bussink, and J.H.A.M. Kaanders Interaction of EGFR with the tumour microenvironment: implications for radiation treatment Radiother Oncol 108 2013 17 23
    • (2013) Radiother Oncol , vol.108 , pp. 17-23
    • Nijkamp, M.M.1    Span, P.N.2    Bussink, J.3    Kaanders, J.H.A.M.4
  • 91
    • 84863200567 scopus 로고    scopus 로고
    • Homologous recombination is activated at early time points following exposure to cobalt chloride induced hypoxic conditions in Saccharomyces cerevisiae
    • R.C. Meena, N. Kumar, S. Nath, and A. Chakrabarti Homologous recombination is activated at early time points following exposure to cobalt chloride induced hypoxic conditions in Saccharomyces cerevisiae Indian J Microbiol 52 2012 209 214
    • (2012) Indian J Microbiol , vol.52 , pp. 209-214
    • Meena, R.C.1    Kumar, N.2    Nath, S.3    Chakrabarti, A.4
  • 92
    • 84858119890 scopus 로고    scopus 로고
    • Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability
    • R. Kumareswaran, O. Ludkovski, A. Meng, J. Sykes, M. Pintilie, and R.G. Bristow Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability J Cell Sci 125 2012 189 199
    • (2012) J Cell Sci , vol.125 , pp. 189-199
    • Kumareswaran, R.1    Ludkovski, O.2    Meng, A.3    Sykes, J.4    Pintilie, M.5    Bristow, R.G.6
  • 93
    • 73649094822 scopus 로고    scopus 로고
    • Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity
    • Y. Kim, Q. Lin, D. Zelterman, and Z. Yun Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity Cancer Res 69 2009 9271 9280
    • (2009) Cancer Res , vol.69 , pp. 9271-9280
    • Kim, Y.1    Lin, Q.2    Zelterman, D.3    Yun, Z.4
  • 94
    • 84862875401 scopus 로고    scopus 로고
    • Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression
    • M.M. Saller, W.C. Prall, D. Docheva, V. Schönitzer, T. Popov, and D. Anz Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression Biochem Biophys Res Commun 423 2012 379 385
    • (2012) Biochem Biophys Res Commun , vol.423 , pp. 379-385
    • Saller, M.M.1    Prall, W.C.2    Docheva, D.3    Schönitzer, V.4    Popov, T.5    Anz, D.6
  • 95
    • 70349754442 scopus 로고    scopus 로고
    • MTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells
    • K. Matsumoto, T. Arao, K. Tanaka, H. Kaneda, K. Kudo, and Y. Fujita MTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells Cancer Res 69 2009 7160 7164
    • (2009) Cancer Res , vol.69 , pp. 7160-7164
    • Matsumoto, K.1    Arao, T.2    Tanaka, K.3    Kaneda, H.4    Kudo, K.5    Fujita, Y.6
  • 96
    • 65349173893 scopus 로고    scopus 로고
    • Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck
    • P. Lassen, J.G. Eriksen, S. Hamilton-Dutoit, T. Tramm, J. Alsner, and J. Overgaard Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck J Clin Oncol 27 2009 1992 1998
    • (2009) J Clin Oncol , vol.27 , pp. 1992-1998
    • Lassen, P.1    Eriksen, J.G.2    Hamilton-Dutoit, S.3    Tramm, T.4    Alsner, J.5    Overgaard, J.6
  • 97
    • 0034600339 scopus 로고    scopus 로고
    • Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
    • M.L. Gillison, W.M. Koch, R.B. Capone, M. Spafford, W.H. Westra, and L. Wu Evidence for a causal association between human papillomavirus and a subset of head and neck cancers J Natl Cancer Inst 92 2000 709 720
    • (2000) J Natl Cancer Inst , vol.92 , pp. 709-720
    • Gillison, M.L.1    Koch, W.M.2    Capone, R.B.3    Spafford, M.4    Westra, W.H.5    Wu, L.6
  • 98
    • 77955282693 scopus 로고    scopus 로고
    • HPV-associated head and neck cancer: A virus-related cancer epidemic
    • S. Marur, G. D'Souza, W.H. Westra, and A.A. Forastiere HPV-associated head and neck cancer: a virus-related cancer epidemic Lancet Oncol 11 2010 781 789
    • (2010) Lancet Oncol , vol.11 , pp. 781-789
    • Marur, S.1    D'Souza, G.2    Westra, W.H.3    Forastiere, A.A.4
  • 100
    • 84879014884 scopus 로고    scopus 로고
    • HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity
    • T. Rieckmann, S. Tribius, T.J. Grob, F. Meyer, C.-J. Busch, and C. Petersen HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity Radiother Oncol 107 2013 242 246
    • (2013) Radiother Oncol , vol.107 , pp. 242-246
    • Rieckmann, T.1    Tribius, S.2    Grob, T.J.3    Meyer, F.4    Busch, C.-J.5    Petersen, C.6
  • 101
    • 84887017554 scopus 로고    scopus 로고
    • HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1
    • C.-J. Busch, M. Kriegs, S. Laban, S. Tribius, R. Knecht, and C. Petersen HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1 Radiother Oncol 108 2013 495 499
    • (2013) Radiother Oncol , vol.108 , pp. 495-499
    • Busch, C.-J.1    Kriegs, M.2    Laban, S.3    Tribius, S.4    Knecht, R.5    Petersen, C.6
  • 102
    • 74549123751 scopus 로고    scopus 로고
    • HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer
    • P. Lassen, J.G. Eriksen, S. Hamilton-Dutoit, T. Tramm, J. Alsner, and J. Overgaard HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer Radiother Oncol 94 2010 30 35
    • (2010) Radiother Oncol , vol.94 , pp. 30-35
    • Lassen, P.1    Eriksen, J.G.2    Hamilton-Dutoit, S.3    Tramm, T.4    Alsner, J.5    Overgaard, J.6
  • 103
    • 33748155274 scopus 로고    scopus 로고
    • Clinical implications of human papillomavirus in head and neck cancers
    • C. Fakhry, and M.L. Gillison Clinical implications of human papillomavirus in head and neck cancers J Clin Oncol 24 2006 2606 2611
    • (2006) J Clin Oncol , vol.24 , pp. 2606-2611
    • Fakhry, C.1    Gillison, M.L.2
  • 104
    • 79960367969 scopus 로고    scopus 로고
    • The influence of HPV-associated p16-expression on accelerated fractionated radiotherapy in head and neck cancer: Evaluation of the randomised DAHANCA 6&7 trial
    • P. Lassen, J.G. Eriksen, A. Krogdahl, M.H. Therkildsen, B.P. Ulhøi, and M. Overgaard The influence of HPV-associated p16-expression on accelerated fractionated radiotherapy in head and neck cancer: evaluation of the randomised DAHANCA 6&7 trial Radiother Oncol 100 2011 49 55
    • (2011) Radiother Oncol , vol.100 , pp. 49-55
    • Lassen, P.1    Eriksen, J.G.2    Krogdahl, A.3    Therkildsen, M.H.4    Ulhøi, B.P.5    Overgaard, M.6
  • 105
    • 79960344338 scopus 로고    scopus 로고
    • Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck-A systematic review and meta-analysis
    • J. Overgaard Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck-a systematic review and meta-analysis Radiother Oncol 100 2011 22 32
    • (2011) Radiother Oncol , vol.100 , pp. 22-32
    • Overgaard, J.1
  • 106
    • 84867079837 scopus 로고    scopus 로고
    • Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo
    • C. Lin, Y. Yu, H.-G. Zhao, A. Yang, H. Yan, and Y. Cui Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo Radiother Oncol 104 2012 395 400
    • (2012) Radiother Oncol , vol.104 , pp. 395-400
    • Lin, C.1    Yu, Y.2    Zhao, H.-G.3    Yang, A.4    Yan, H.5    Cui, Y.6
  • 107
    • 84863188675 scopus 로고    scopus 로고
    • Circulating regulatory T cells of cancer patients receiving radiochemotherapy may be useful to individualize cancer treatment
    • M.A. Schmidt, C. Förtsch, M. Schmidt, T.T. Rau, R. Fietkau, and L.V. Distel Circulating regulatory T cells of cancer patients receiving radiochemotherapy may be useful to individualize cancer treatment Radiother Oncol 104 2012 131 138
    • (2012) Radiother Oncol , vol.104 , pp. 131-138
    • Schmidt, M.A.1    Förtsch, C.2    Schmidt, M.3    Rau, T.T.4    Fietkau, R.5    Distel, L.V.6
  • 108
    • 67649359533 scopus 로고    scopus 로고
    • Systemic effects of local radiotherapy
    • S.C. Formenti, and S. Demaria Systemic effects of local radiotherapy Lancet Oncol 10 2009 718 726
    • (2009) Lancet Oncol , vol.10 , pp. 718-726
    • Formenti, S.C.1    Demaria, S.2
  • 110
    • 80655127833 scopus 로고    scopus 로고
    • Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages
    • P. Schildkopf, B. Frey, O.J. Ott, Y. Rubner, G. Multhoff, and R. Sauer Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages Radiother Oncol 101 2011 109 115
    • (2011) Radiother Oncol , vol.101 , pp. 109-115
    • Schildkopf, P.1    Frey, B.2    Ott, O.J.3    Rubner, Y.4    Multhoff, G.5    Sauer, R.6
  • 111
    • 84865732679 scopus 로고    scopus 로고
    • Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by β1 integrin inhibition
    • I. Eke, E. Dickreuter, and N. Cordes Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by β1 integrin inhibition Radiother Oncol 104 2012 235 242
    • (2012) Radiother Oncol , vol.104 , pp. 235-242
    • Eke, I.1    Dickreuter, E.2    Cordes, N.3
  • 112
    • 79960363201 scopus 로고    scopus 로고
    • Radiobiology goes 3D: How ECM and cell morphology impact on cell survival after irradiation
    • I. Eke, and N. Cordes Radiobiology goes 3D: how ECM and cell morphology impact on cell survival after irradiation Radiother Oncol 99 2011 271 278
    • (2011) Radiother Oncol , vol.99 , pp. 271-278
    • Eke, I.1    Cordes, N.2
  • 113
    • 28544438548 scopus 로고    scopus 로고
    • Radiation and the microenvironment - Tumorigenesis and therapy
    • M.H. Barcellos-Hoff, C. Park, and E.G. Wright Radiation and the microenvironment - tumorigenesis and therapy Nat Rev Cancer 5 2005 867 875
    • (2005) Nat Rev Cancer , vol.5 , pp. 867-875
    • Barcellos-Hoff, M.H.1    Park, C.2    Wright, E.G.3
  • 114
    • 0038751716 scopus 로고    scopus 로고
    • Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro
    • N. Cordes, and D. Van Beuningen Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro Br J Cancer 88 2003 1470 1479
    • (2003) Br J Cancer , vol.88 , pp. 1470-1479
    • Cordes, N.1    Van Beuningen, D.2
  • 115
    • 0037799517 scopus 로고    scopus 로고
    • Cell adhesion-mediated radioresistance (CAM-RR). Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro
    • N. Cordes, and V. Meineke Cell adhesion-mediated radioresistance (CAM-RR). Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro Strahlenther Onkol 179 2003 337 344
    • (2003) Strahlenther Onkol , vol.179 , pp. 337-344
    • Cordes, N.1    Meineke, V.2
  • 116
    • 0033213954 scopus 로고    scopus 로고
    • Extracellular matrix and radiation G1 cell cycle arrest in human fibroblasts
    • M. Dimitrijevic-Bussod, V.S. Balzaretti-Maggi, and D.M. Gadbois Extracellular matrix and radiation G1 cell cycle arrest in human fibroblasts Cancer Res 59 1999 4843 4847
    • (1999) Cancer Res , vol.59 , pp. 4843-4847
    • Dimitrijevic-Bussod, M.1    Balzaretti-Maggi, V.S.2    Gadbois, D.M.3
  • 117
    • 84873160542 scopus 로고    scopus 로고
    • Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
    • M. Mimeault, and S.K. Batra Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells J Cell Mol Med 17 2013 30 54
    • (2013) J Cell Mol Med , vol.17 , pp. 30-54
    • Mimeault, M.1    Batra, S.K.2
  • 119
    • 54249151684 scopus 로고    scopus 로고
    • Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
    • B. Das, R. Tsuchida, D. Malkin, G. Koren, S. Baruchel, and H. Yeger Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction Stem Cells 26 2008 1818 1830
    • (2008) Stem Cells , vol.26 , pp. 1818-1830
    • Das, B.1    Tsuchida, R.2    Malkin, D.3    Koren, G.4    Baruchel, S.5    Yeger, H.6
  • 122
    • 79959238013 scopus 로고    scopus 로고
    • Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
    • J.P. Medema, and L. Vermeulen Microenvironmental regulation of stem cells in intestinal homeostasis and cancer Nature 474 2011 318 326
    • (2011) Nature , vol.474 , pp. 318-326
    • Medema, J.P.1    Vermeulen, L.2
  • 123
    • 84868367617 scopus 로고    scopus 로고
    • FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: Results from the DAHANCA 24 trial
    • L.S. Mortensen, J. Johansen, J. Kallehauge, H. Primdahl, M. Busk, and P. Lassen FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial Radiother Oncol 105 2012 14 20
    • (2012) Radiother Oncol , vol.105 , pp. 14-20
    • Mortensen, L.S.1    Johansen, J.2    Kallehauge, J.3    Primdahl, H.4    Busk, M.5    Lassen, P.6
  • 124
    • 84868341360 scopus 로고    scopus 로고
    • Correlation of PET images of metabolism, proliferation and hypoxia to characterize tumor phenotype in patients with cancer of the oropharynx
    • M.J. Nyflot, P.M. Harari, S. Yip, S.B. Perlman, and R. Jeraj Correlation of PET images of metabolism, proliferation and hypoxia to characterize tumor phenotype in patients with cancer of the oropharynx Radiother Oncol 105 2012 36 40
    • (2012) Radiother Oncol , vol.105 , pp. 36-40
    • Nyflot, M.J.1    Harari, P.M.2    Yip, S.3    Perlman, S.B.4    Jeraj, R.5
  • 125
    • 84868360868 scopus 로고    scopus 로고
    • Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer
    • D. Zips, K. Zöphel, N. Abolmaali, R. Perrin, A. Abramyuk, and R. Haase Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer Radiother Oncol 105 2012 21 28
    • (2012) Radiother Oncol , vol.105 , pp. 21-28
    • Zips, D.1    Zöphel, K.2    Abolmaali, N.3    Perrin, R.4    Abramyuk, A.5    Haase, R.6
  • 126
    • 84868348070 scopus 로고    scopus 로고
    • Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: A comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry
    • L.-B.-A. Tran, A. Bol, D. Labar, B. Jordan, J. Magat, and L. Mignion Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: a comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry Radiother Oncol 105 2012 29 35
    • (2012) Radiother Oncol , vol.105 , pp. 29-35
    • Tran, L.-B.-A.1    Bol, A.2    Labar, D.3    Jordan, B.4    Magat, J.5    Mignion, L.6
  • 127
    • 84857913688 scopus 로고    scopus 로고
    • Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging
    • K.M. Ovrebø, T. Hompland, B. Mathiesen, and E.K. Rofstad Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging Radiother Oncol 102 2012 429 435
    • (2012) Radiother Oncol , vol.102 , pp. 429-435
    • Ovrebø, K.M.1    Hompland, T.2    Mathiesen, B.3    Rofstad, E.K.4
  • 128
    • 79960370596 scopus 로고    scopus 로고
    • Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: A preclinical study
    • L.S. Mortensen, M. Busk, M. Nordsmark, S. Jakobsen, J. Theil, and J. Overgaard Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: a preclinical study Radiother Oncol 99 2011 418 423
    • (2011) Radiother Oncol , vol.99 , pp. 418-423
    • Mortensen, L.S.1    Busk, M.2    Nordsmark, M.3    Jakobsen, S.4    Theil, J.5    Overgaard, J.6
  • 129
    • 79952013846 scopus 로고    scopus 로고
    • Molecular imaging-based dose painting: A novel paradigm for radiation therapy prescription
    • S.M. Bentzen, and V. Grégoire Molecular imaging-based dose painting: a novel paradigm for radiation therapy prescription Semin Radiat Oncol 21 2011 101 110
    • (2011) Semin Radiat Oncol , vol.21 , pp. 101-110
    • Bentzen, S.M.1    Grégoire, V.2
  • 130
    • 59649100572 scopus 로고    scopus 로고
    • Strategies for biologic image-guided dose escalation: A review
    • A. Søvik, E. Malinen, and D.R. Olsen Strategies for biologic image-guided dose escalation: a review Int J Radiat Oncol Biol Phys 73 2009 650 658
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 650-658
    • Søvik, A.1    Malinen, E.2    Olsen, D.R.3


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