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Volumn 99, Issue 3, 2011, Pages 279-286

Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures

Author keywords

3D cell culture; CETUXIMAB; EGFR; Focal adhesion kinase; Ionizing radiation

Indexed keywords

2 [5 CHLORO 2 (2 METHOXY 4 MORPHOLINOANILINO) 4 PYRIMIDINYLAMINO] N METHYLBENZAMIDE; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE; LAMININ; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

EID: 79960341728     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2011.06.006     Document Type: Article
Times cited : (41)

References (50)
  • 1
    • 79960344338 scopus 로고    scopus 로고
    • Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - A systematic review and meta-analysis
    • Overgaard J. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - A systematic review and meta-analysis. Radiother Oncol 2011
    • (2011) Radiother Oncol
    • Overgaard, J.1
  • 2
    • 66949114269 scopus 로고    scopus 로고
    • Chemoradiotherapy of head and neck cancer-can the bumble bee fly?
    • J. Overgaard Chemoradiotherapy of head and neck cancer-can the bumble bee fly? Radiother Oncol 92 2009 1 3
    • (2009) Radiother Oncol , vol.92 , pp. 1-3
    • Overgaard, J.1
  • 3
    • 33746485766 scopus 로고    scopus 로고
    • Epidermal Growth Factor Receptor Targeting in Cancer
    • DOI 10.1053/j.seminoncol.2006.04.003, PII S0093775406001771
    • J. Mendelsohn, and J. Baselga Epidermal growth factor receptor targeting in cancer Semin Oncol 33 2006 369 385 (Pubitemid 44142736)
    • (2006) Seminars in Oncology , vol.33 , Issue.4 , pp. 369-385
    • Mendelsohn, J.1    Baselga, J.2
  • 4
    • 63749086305 scopus 로고    scopus 로고
    • ErbB receptors and signaling pathways in cancer
    • N.E. Hynes, and G. MacDonald ErbB receptors and signaling pathways in cancer Curr Opin Cell Biol 21 2009 177 184
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 177-184
    • Hynes, N.E.1    MacDonald, G.2
  • 5
    • 34250345258 scopus 로고    scopus 로고
    • EGFR-targeted anti-cancer drugs in radiotherapy: Preclinical evaluation of mechanisms
    • DOI 10.1016/j.radonc.2007.04.006, PII S0167814007001557, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
    • M. Baumann, M. Krause, E. Dikomey, K. Dittmann, W. Dorr, and U. Kasten-Pisula EGFR-targeted anti-cancer drugs in radiotherapy: preclinical evaluation of mechanisms Radiother Oncol 83 2007 238 248 (Pubitemid 46915540)
    • (2007) Radiotherapy and Oncology , vol.83 , Issue.3 , pp. 238-248
    • Baumann, M.1    Krause, M.2    Dikomey, E.3    Dittmann, K.4    Dorr, W.5    Kasten-Pisula, U.6    Rodemann, H.P.7
  • 6
    • 36849032852 scopus 로고    scopus 로고
    • Radiation-induced EGFR-signaling and control of DNA-damage repair
    • DOI 10.1080/09553000701769970, PII 787783391
    • H.P. Rodemann, K. Dittmann, and M. Toulany Radiation-induced EGFR-signaling and control of DNA-damage repair Int J Radiat Biol 83 2007 781 791 (Pubitemid 350219102)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.11-12 , pp. 781-791
    • Rodemann, H.P.1    Dittmann, K.2    Toulany, M.3
  • 7
    • 78149358861 scopus 로고    scopus 로고
    • ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway
    • M. Toulany, M. Minjgee, R. Kehlbach, J. Chen, M. Baumann, and H.P. Rodemann ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway Radiother Oncol 97 2010 338 345
    • (2010) Radiother Oncol , vol.97 , pp. 338-345
    • Toulany, M.1    Minjgee, M.2    Kehlbach, R.3    Chen, J.4    Baumann, M.5    Rodemann, H.P.6
  • 8
    • 78649988884 scopus 로고    scopus 로고
    • Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer
    • F. Di Fiore, R. Sesboue, P. Michel, J.C. Sabourin, and T. Frebourg Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer Br J Cancer 103 2010 1765 1772
    • (2010) Br J Cancer , vol.103 , pp. 1765-1772
    • Di Fiore, F.1    Sesboue, R.2    Michel, P.3    Sabourin, J.C.4    Frebourg, T.5
  • 9
    • 34250336116 scopus 로고    scopus 로고
    • EGFR-TK inhibition before radiotherapy reduces tumour volume but does not improve local control: Differential response of cancer stem cells and nontumourigenic cells?
    • DOI 10.1016/j.radonc.2007.04.014, PII S0167814007001697, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
    • M. Krause, J. Prager, X. Zhou, A. Yaromina, A. Dorfler, and W. Eicheler EGFR-TK inhibition before radiotherapy reduces tumour volume but does not improve local control: differential response of cancer stem cells and nontumourigenic cells? Radiother Oncol 83 2007 316 325 (Pubitemid 46915543)
    • (2007) Radiotherapy and Oncology , vol.83 , Issue.3 , pp. 316-325
    • Krause, M.1    Prager, J.2    Zhou, X.3    Yaromina, A.4    Dorfler, A.5    Eicheler, W.6    Baumann, M.7
  • 11
    • 69949157387 scopus 로고    scopus 로고
    • Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro
    • N. Zhang, K. Erjala, J. Kulmala, X. Qiu, M. Sundvall, and K. Elenius Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro Radiother Oncol 92 2009 388 392
    • (2009) Radiother Oncol , vol.92 , pp. 388-392
    • Zhang, N.1    Erjala, K.2    Kulmala, J.3    Qiu, X.4    Sundvall, M.5    Elenius, K.6
  • 12
    • 70449635892 scopus 로고    scopus 로고
    • Reverse resistance to radiation in KYSE-150R esophageal carcinoma cell after epidermal growth factor receptor signal pathway inhibition by cetuximab
    • Z. Jing, L. Gong, C.Y. Xie, L. Zhang, H.F. Su, and X. Deng Reverse resistance to radiation in KYSE-150R esophageal carcinoma cell after epidermal growth factor receptor signal pathway inhibition by cetuximab Radiother Oncol 93 2009 468 473
    • (2009) Radiother Oncol , vol.93 , pp. 468-473
    • Jing, Z.1    Gong, L.2    Xie, C.Y.3    Zhang, L.4    Su, H.F.5    Deng, X.6
  • 13
    • 73249143536 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
    • J.A. Bonner, P.M. Harari, J. Giralt, R.B. Cohen, C.U. Jones, and R.K. Sur Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival Lancet Oncol 11 2010 21 28
    • (2010) Lancet Oncol , vol.11 , pp. 21-28
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3    Cohen, R.B.4    Jones, C.U.5    Sur, R.K.6
  • 14
    • 44449161951 scopus 로고    scopus 로고
    • Locoregionally advanced head and neck cancer treated with primary radiotherapy: A comparison of the addition of cetuximab or chemotherapy and the impact of protocol treatment
    • J.J. Caudell, S.M. Sawrie, S.A. Spencer, R.A. Desmond, W.R. Carroll, and G.E. Peters Locoregionally advanced head and neck cancer treated with primary radiotherapy: a comparison of the addition of cetuximab or chemotherapy and the impact of protocol treatment Int J Radiat Oncol Biol Phys 71 2008 676 681
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 676-681
    • Caudell, J.J.1    Sawrie, S.M.2    Spencer, S.A.3    Desmond, R.A.4    Carroll, W.R.5    Peters, G.E.6
  • 15
    • 36849091893 scopus 로고    scopus 로고
    • An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading
    • DOI 10.1080/09553000701694327, PII 783201012
    • S. Hehlgans, I. Eke, and N. Cordes An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading Int J Radiat Biol 83 2007 769 779 (Pubitemid 350219099)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.11-12 , pp. 769-779
    • Hehlgans, S.1    Eke, I.2    Cordes, N.3
  • 16
    • 0033229747 scopus 로고    scopus 로고
    • Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase
    • DOI 10.1083/jcb.147.3.611
    • M.W. Renshaw, L.S. Price, and M.A. Schwartz Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase J Cell Biol 147 1999 611 618 (Pubitemid 29523466)
    • (1999) Journal of Cell Biology , vol.147 , Issue.3 , pp. 611-618
    • Renshaw, M.W.1    Price, L.S.2    Schwartz, M.A.3
  • 17
    • 76249123378 scopus 로고    scopus 로고
    • A PAK-activated linker for EGFR and FAK
    • A. Tomar, and D.D. Schlaepfer A PAK-activated linker for EGFR and FAK Dev Cell 18 2010 170 172
    • (2010) Dev Cell , vol.18 , pp. 170-172
    • Tomar, A.1    Schlaepfer, D.D.2
  • 18
    • 33748040450 scopus 로고    scopus 로고
    • Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin
    • DOI 10.1016/j.radonc.2006.07.028, PII S0167814006003070, Papers from ICTR 2006. International Conference on Transtational Research and Pre-Clinical Stratigies in Rediation Oncology
    • I. Eke, V. Sandfort, A. Mischkus, M. Baumann, and N. Cordes Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin Radiother Oncol 80 2006 178 184 (Pubitemid 44301542)
    • (2006) Radiotherapy and Oncology , vol.80 , Issue.2 , pp. 178-184
    • Eke, I.1    Sandfort, V.2    Mischkus, A.3    Baumann, M.4    Cordes, N.5
  • 19
    • 36849038939 scopus 로고    scopus 로고
    • Pharmacological inhibition of EGFR tyrosine kinase affects ILK-mediated cellular radiosensitization in vitro
    • DOI 10.1080/09553000701727549, PII 787787934
    • I. Eke, V. Sandfort, K. Storch, M. Baumann, B. Roper, and N. Cordes Pharmacological inhibition of EGFR tyrosine kinase affects ILK-mediated cellular radiosensitization in vitro Int J Radiat Biol 83 2007 793 802 (Pubitemid 350219106)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.11-12 , pp. 793-802
    • Eke, I.1    Sandfort, V.2    Storch, K.3    Baumann, M.4    Roper, B.5    Cordes, N.6
  • 20
    • 0037799517 scopus 로고    scopus 로고
    • Cell adhesion-mediated radioresistance (CAM-RR): Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro
    • DOI 10.1007/s00066-003-1074-4
    • N. Cordes, and V. Meineke Cell adhesion-mediated radioresistance (CAM-RR) Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro Strahlenther Onkol 179 2003 337 344 (Pubitemid 36606025)
    • (2003) Strahlentherapie und Onkologie , vol.179 , Issue.5 , pp. 337-344
    • Cordes, N.1    Meineke, V.2
  • 21
    • 77954994889 scopus 로고    scopus 로고
    • PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha
    • I. Eke, U. Koch, S. Hehlgans, V. Sandfort, F. Stanchi, and D. Zips PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha J Clin Invest 120 2010 2516 2527
    • (2010) J Clin Invest , vol.120 , pp. 2516-2527
    • Eke, I.1    Koch, U.2    Hehlgans, S.3    Sandfort, V.4    Stanchi, F.5    Zips, D.6
  • 22
    • 77958534613 scopus 로고    scopus 로고
    • The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures
    • Sandfort V, Eke I, Cordes N. The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures. PLoS One 2010;5
    • (2010) PLoS One , vol.5
    • Sandfort, V.1    Eke, I.2    Cordes, N.3
  • 23
    • 0242551706 scopus 로고    scopus 로고
    • Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro
    • DOI 10.1080/09553000310001610231
    • C. Beinke, D. Van Beuningen, and N. Cordes Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro Int J Radiat Biol 79 2003 721 731 (Pubitemid 37378539)
    • (2003) International Journal of Radiation Biology , vol.79 , Issue.9 , pp. 721-731
    • Beinke, C.1    Van Beuningen, D.2    Cordes, N.3
  • 26
    • 0031657454 scopus 로고    scopus 로고
    • Focal adhesion kinase and its potential involvement in tumor invasion and metastasis
    • DOI 10.1002/(SICI)1097-0347(199812)20:8<745::AID-HED14>3.0.CO;2-Z
    • L.J. Kornberg Focal adhesion kinase and its potential involvement in tumor invasion and metastasis Head Neck 20 1998 745 752 (Pubitemid 28462832)
    • (1998) Head and Neck , vol.20 , Issue.8 , pp. 745-752
    • Kornberg, L.J.1
  • 27
    • 78449268040 scopus 로고    scopus 로고
    • Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer
    • J.H. Park, B.L. Lee, J. Yoon, J. Kim, M.A. Kim, and H.K. Yang Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer Hum Pathol 41 2010 1664 1673
    • (2010) Hum Pathol , vol.41 , pp. 1664-1673
    • Park, J.H.1    Lee, B.L.2    Yoon, J.3    Kim, J.4    Kim, M.A.5    Yang, H.K.6
  • 28
    • 33745186178 scopus 로고    scopus 로고
    • The signaling and biological implications of FAK overexpression in cancer
    • P.M. Siesser, and S.K. Hanks The signaling and biological implications of FAK overexpression in cancer Clin Cancer Res 12 2006 3233 3237
    • (2006) Clin Cancer Res , vol.12 , pp. 3233-3237
    • Siesser, P.M.1    Hanks, S.K.2
  • 29
    • 0037509990 scopus 로고    scopus 로고
    • Focal adhesion kinase: The first ten years
    • DOI 10.1242/jcs.00373
    • J.T. Parsons Focal adhesion kinase: the first ten years J Cell Sci 116 2003 1409 1416 (Pubitemid 36527488)
    • (2003) Journal of Cell Science , vol.116 , Issue.8 , pp. 1409-1416
    • Parsons, J.T.1
  • 31
    • 75949092766 scopus 로고    scopus 로고
    • SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration
    • W. Long, P. Yi, L. Amazit, H.L. LaMarca, F. Ashcroft, and R. Kumar SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration Mol Cell 37 2010 321 332
    • (2010) Mol Cell , vol.37 , pp. 321-332
    • Long, W.1    Yi, P.2    Amazit, L.3    Lamarca, H.L.4    Ashcroft, F.5    Kumar, R.6
  • 32
    • 69949162504 scopus 로고    scopus 로고
    • 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226
    • S. Hehlgans, I. Lange, I. Eke, and N. Cordes 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226 Radiother Oncol 92 2009 371 378
    • (2009) Radiother Oncol , vol.92 , pp. 371-378
    • Hehlgans, S.1    Lange, I.2    Eke, I.3    Cordes, N.4
  • 33
    • 79151480076 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells
    • S. Hiscox, P. Barnfather, E. Hayes, P. Bramble, J. Christensen, and R.I. Nicholson Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells Breast Cancer Res Treat 125 2011 659 669
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 659-669
    • Hiscox, S.1    Barnfather, P.2    Hayes, E.3    Bramble, P.4    Christensen, J.5    Nicholson, R.I.6
  • 34
    • 40749087685 scopus 로고    scopus 로고
    • TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR
    • DOI 10.1002/mc.20380
    • V.M. Golubovskaya, C. Virnig, and W.G. Cance TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR Mol Carcinog 47 2008 222 234 (Pubitemid 351398065)
    • (2008) Molecular Carcinogenesis , vol.47 , Issue.3 , pp. 222-234
    • Golubovskaya, V.M.1    Virnig, C.2    Cance, W.G.3
  • 35
    • 77953526787 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma
    • E.A. Beierle, X. Ma, J. Stewart, C. Nyberg, A. Trujillo, and W.G. Cance Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma Cell Cycle 9 2010 1005 1015
    • (2010) Cell Cycle , vol.9 , pp. 1005-1015
    • Beierle, E.A.1    Ma, X.2    Stewart, J.3    Nyberg, C.4    Trujillo, A.5    Cance, W.G.6
  • 36
    • 66349129097 scopus 로고    scopus 로고
    • Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts
    • J. Schwock, N. Dhani, M.P. Cao, J. Zheng, R. Clarkson, and N. Radulovich Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts Cancer Res 69 2009 4750 4759
    • (2009) Cancer Res , vol.69 , pp. 4750-4759
    • Schwock, J.1    Dhani, N.2    Cao, M.P.3    Zheng, J.4    Clarkson, R.5    Radulovich, N.6
  • 37
    • 79952746902 scopus 로고    scopus 로고
    • Final report of phase i clinical, pharmacokinetic (PK), pharmacodynamic (PD) study of PF-00562271 targeting focal adhesion kinase (FAK) in patients (pts) with solid tumors
    • (suppl; abstr 3028)
    • N.D. Dhani, H.A. Burris III, L.L. Siu, D.R. Camidge, L.R. Mileshkin, H. Xu, K.J. Pierce, N.R. Fahey, H.J.S. Fingert, and M. Shreeve Final report of phase I clinical, pharmacokinetic (PK), pharmacodynamic (PD) study of PF-00562271 targeting focal adhesion kinase (FAK) in patients (pts) with solid tumors J Clin Oncol 28 2010 15s (suppl; abstr 3028)
    • (2010) J Clin Oncol , vol.28
    • Dhani, N.D.1    Burris Iii, H.A.2    Siu, L.L.3    Camidge, D.R.4    Mileshkin, L.R.5    Xu, H.6    Pierce, K.J.7    Fahey, N.R.8    Fingert, H.J.S.9    Shreeve, M.10
  • 38
    • 33746894693 scopus 로고    scopus 로고
    • Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer
    • DOI 10.1158/0008-5472.CAN-06-0515
    • M.V. Fournier, K.J. Martin, P.A. Kenny, K. Xhaja, I. Bosch, and P. Yaswen Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer Cancer Res 66 2006 7095 7102 (Pubitemid 44197686)
    • (2006) Cancer Research , vol.66 , Issue.14 , pp. 7095-7102
    • Fournier, M.V.1    Martin, K.J.2    Kenny, P.A.3    Xhaja, K.4    Bosch, I.5    Yaswen, P.6    Bissell, M.J.7
  • 39
    • 33748967069 scopus 로고    scopus 로고
    • Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer
    • C.M. Nelson, and M.J. Bissell Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer Annu Rev Cell Dev Biol 22 2006 287 309
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 287-309
    • Nelson, C.M.1    Bissell, M.J.2
  • 40
    • 68149092724 scopus 로고    scopus 로고
    • The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck
    • I. Eke, F. Leonhardt, K. Storch, S. Hehlgans, and N. Cordes The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck PLoS One 4 2009 e6434
    • (2009) PLoS One , vol.4 , pp. 6434
    • Eke, I.1    Leonhardt, F.2    Storch, K.3    Hehlgans, S.4    Cordes, N.5
  • 41
    • 77952847488 scopus 로고    scopus 로고
    • Three-dimensional cell growth confers radioresistance by chromatin density modification
    • K. Storch, I. Eke, K. Borgmann, M. Krause, C. Richter, and K. Becker Three-dimensional cell growth confers radioresistance by chromatin density modification Cancer Res 70 2010 3925 3934
    • (2010) Cancer Res , vol.70 , pp. 3925-3934
    • Storch, K.1    Eke, I.2    Borgmann, K.3    Krause, M.4    Richter, C.5    Becker, K.6
  • 42
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • DOI 10.1038/nrm2236, PII NRM2236
    • F. Pampaloni, E.G. Reynaud, and E.H. Stelzer The third dimension bridges the gap between cell culture and live tissue Nat Rev Mol Cell Biol 8 2007 839 845 (Pubitemid 47462131)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.10 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.G.2    Stelzer, E.H.K.3
  • 44
    • 77954353421 scopus 로고    scopus 로고
    • Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin
    • J.M. Nam, Y. Onodera, M.J. Bissell, and C.C. Park Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin Cancer Res 70 2010 5238 5248
    • (2010) Cancer Res , vol.70 , pp. 5238-5248
    • Nam, J.M.1    Onodera, Y.2    Bissell, M.J.3    Park, C.C.4
  • 45
    • 0036726312 scopus 로고    scopus 로고
    • β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
    • DOI 10.1016/S1535-6108(02)00125-3
    • V.M. Weaver, S. Lelievre, J.N. Lakins, M.A. Chrenek, J.C. Jones, and F. Giancotti Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium Cancer Cell 2 2002 205 216 (Pubitemid 41043976)
    • (2002) Cancer Cell , vol.2 , Issue.3 , pp. 205-216
    • Weaver, V.M.1    Lelievre, S.2    Lakins, J.N.3    Chrenek, M.A.4    Jones, J.C.R.5    Giancotti, F.6    Werb, Z.7    Bissell, M.J.8
  • 47
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • DOI 10.1126/science.1064829
    • E. Cukierman, R. Pankov, D.R. Stevens, and K.M. Yamada Taking cell-matrix adhesions to the third dimension Science 294 2001 1708 1712 (Pubitemid 33104840)
    • (2001) Science , vol.294 , Issue.5547 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 48
    • 0036229695 scopus 로고    scopus 로고
    • Integrin regulation of growth factor receptors
    • K.M. Yamada, and S. Even-Ram Integrin regulation of growth factor receptors Nat Cell Biol 4 2002 E75 E76
    • (2002) Nat Cell Biol , vol.4
    • Yamada, K.M.1    Even-Ram, S.2
  • 49
    • 63449122814 scopus 로고    scopus 로고
    • Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells
    • S. Benavente, S. Huang, E.A. Armstrong, A. Chi, K.T. Hsu, and D.L. Wheeler Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells Clin Cancer Res 15 2009 1585 1592
    • (2009) Clin Cancer Res , vol.15 , pp. 1585-1592
    • Benavente, S.1    Huang, S.2    Armstrong, E.A.3    Chi, A.4    Hsu, K.T.5    Wheeler, D.L.6


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