-
1
-
-
84887025550
-
Pattern of CAIX expression is prognostic for outcome and predicts response to ARCON in patients with laryngeal cancer treated in a phase III randomized trial
-
S. Rademakers, I. Hoogsteen, and P. Rijken Pattern of CAIX expression is prognostic for outcome and predicts response to ARCON in patients with laryngeal cancer treated in a phase III randomized trial Radiother Oncol 108 2013 517 522
-
(2013)
Radiother Oncol
, vol.108
, pp. 517-522
-
-
Rademakers, S.1
Hoogsteen, I.2
Rijken, P.3
-
2
-
-
26444466467
-
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
-
M. Nordsmark, S.M. Bentzen, and V. Rudat Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study Radiother Oncol 77 2005 18 24
-
(2005)
Radiother Oncol
, vol.77
, pp. 18-24
-
-
Nordsmark, M.1
Bentzen, S.M.2
Rudat, V.3
-
3
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
M.W. Dewhirst, Y. Cao, and B. Moeller Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response Nat Rev Cancer 8 2008 425 437
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 425-437
-
-
Dewhirst, M.W.1
Cao, Y.2
Moeller, B.3
-
4
-
-
84868355072
-
Vascular abnormalities associated with acute hypoxia in human melanoma xenografts
-
T.G. Simonsen, J.V. Gaustad, M.N. Leinaas, and E.K. Rofstad Vascular abnormalities associated with acute hypoxia in human melanoma xenografts Radiother Oncol 105 2012 72 78
-
(2012)
Radiother Oncol
, vol.105
, pp. 72-78
-
-
Simonsen, T.G.1
Gaustad, J.V.2
Leinaas, M.N.3
Rofstad, E.K.4
-
5
-
-
0035700693
-
Clinical relevance of intermittent tumour blood flow
-
R.E. Durand, and C. Aquino-Parsons Clinical relevance of intermittent tumour blood flow Acta Oncol 40 2001 929 936
-
(2001)
Acta Oncol
, vol.40
, pp. 929-936
-
-
Durand, R.E.1
Aquino-Parsons, C.2
-
6
-
-
33751249607
-
Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies
-
M.G. Magagnin, M. Koritzinsky, and B.G. Wouters Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies Drug Resist Updat 9 2006 185 197
-
(2006)
Drug Resist Updat
, vol.9
, pp. 185-197
-
-
Magagnin, M.G.1
Koritzinsky, M.2
Wouters, B.G.3
-
7
-
-
84455209531
-
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck
-
K. Toustrup, B.S. Sorensen, P. Lassen, C. Wiuf, J. Alsner, and J. Overgaard Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck Radiother Oncol 102 2012 122 129
-
(2012)
Radiother Oncol
, vol.102
, pp. 122-129
-
-
Toustrup, K.1
Sorensen, B.S.2
Lassen, P.3
Wiuf, C.4
Alsner, J.5
Overgaard, J.6
-
8
-
-
84868374271
-
Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo
-
X. Sun, L. Xing, and X. Deng Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo Radiother Oncol 105 2012 57 63
-
(2012)
Radiother Oncol
, vol.105
, pp. 57-63
-
-
Sun, X.1
Xing, L.2
Deng, X.3
-
9
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
D. Ron, and P. Walter Signal integration in the endoplasmic reticulum unfolded protein response Nat Rev Mol Cell Biol 8 2007 519 529
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
10
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
K.M. Rouschop, T. van den Beucken, and L. Dubois The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 J Clin Invest 120 2010 127 141
-
(2010)
J Clin Invest
, vol.120
, pp. 127-141
-
-
Rouschop, K.M.1
Van Den Beucken, T.2
Dubois, L.3
-
11
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
D.F. Egan, D.B. Shackelford, and M.M. Mihaylova Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy Science 331 2011 456 461
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
-
12
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
N. Hosokawa, T. Hara, and T. Kaizuka Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy Mol Biol Cell 20 2009 1981 1991
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
-
13
-
-
77951221542
-
The role of the Atg1/ULK1 complex in autophagy regulation
-
N. Mizushima The role of the Atg1/ULK1 complex in autophagy regulation Curr Opin Cell Biol 22 2010 132 139
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 132-139
-
-
Mizushima, N.1
-
14
-
-
79551507263
-
AMPK-dependent phosphorylation of ULK1 induces autophagy
-
M. Zhao, and D.J. Klionsky AMPK-dependent phosphorylation of ULK1 induces autophagy Cell Metab 13 2011 119 120
-
(2011)
Cell Metab
, vol.13
, pp. 119-120
-
-
Zhao, M.1
Klionsky, D.J.2
-
15
-
-
84871429513
-
Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival
-
L.R. Pike, D.C. Singleton, and F. Buffa Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival Biochem J 449 2013 389 400
-
(2013)
Biochem J
, vol.449
, pp. 389-400
-
-
Pike, L.R.1
Singleton, D.C.2
Buffa, F.3
-
16
-
-
69949112039
-
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
-
K.M. Rouschop, C.H. Ramaekers, and M.B. Schaaf Autophagy is required during cycling hypoxia to lower production of reactive oxygen species Radiother Oncol 92 2009 411 416
-
(2009)
Radiother Oncol
, vol.92
, pp. 411-416
-
-
Rouschop, K.M.1
Ramaekers, C.H.2
Schaaf, M.B.3
-
17
-
-
84876146036
-
Predictive value of hypoxia, proliferation and tyrosine kinase receptors for EGFR-inhibition and radiotherapy sensitivity in head and neck cancer models
-
H. Stegeman, J.H. Kaanders, and A.J. van der Kogel Predictive value of hypoxia, proliferation and tyrosine kinase receptors for EGFR-inhibition and radiotherapy sensitivity in head and neck cancer models Radiother Oncol 106 2013 383 389
-
(2013)
Radiother Oncol
, vol.106
, pp. 383-389
-
-
Stegeman, H.1
Kaanders, J.H.2
Van Der Kogel, A.J.3
-
18
-
-
0035577208
-
Patterns of proliferation related to vasculature in human head-and-neck carcinomas before and after transplantation in nude mice
-
K.I. Wijffels, J.H. Kaanders, and H.A. Marres Patterns of proliferation related to vasculature in human head-and-neck carcinomas before and after transplantation in nude mice Int J Radiat Oncol Biol Phys 51 2001 1346 1353
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 1346-1353
-
-
Wijffels, K.I.1
Kaanders, J.H.2
Marres, H.A.3
-
19
-
-
36149001337
-
Gene expression profiling to predict outcome after chemoradiation in head and neck cancer
-
J. Pramana, M.W. Van den Brekel, and M.L. van Velthuysen Gene expression profiling to predict outcome after chemoradiation in head and neck cancer Int J Radiat Oncol Biol Phys 69 2007 1544 1552
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
, pp. 1544-1552
-
-
Pramana, J.1
Van Den Brekel, M.W.2
Van Velthuysen, M.L.3
-
20
-
-
80655144415
-
Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T
-
C.H. Ramaekers, T. van den Beucken, and A. Meng Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T Radiother Oncol 101 2011 190 197
-
(2011)
Radiother Oncol
, vol.101
, pp. 190-197
-
-
Ramaekers, C.H.1
Van Den Beucken, T.2
Meng, A.3
-
21
-
-
79960360062
-
E-cadherin loss associated with EMT promotes radioresistance in human tumor cells
-
J. Theys, B. Jutten, and R. Habets E-cadherin loss associated with EMT promotes radioresistance in human tumor cells Radiother Oncol 99 2011 392 397
-
(2011)
Radiother Oncol
, vol.99
, pp. 392-397
-
-
Theys, J.1
Jutten, B.2
Habets, R.3
-
22
-
-
1842450663
-
Targeting hypoxia tolerance in cancer
-
B.G. Wouters, T. van den Beucken, M.G. Magagnin, P. Lambin, and C. Koumenis Targeting hypoxia tolerance in cancer Drug Resist Updat 7 2004 25 40
-
(2004)
Drug Resist Updat
, vol.7
, pp. 25-40
-
-
Wouters, B.G.1
Van Den Beucken, T.2
Magagnin, M.G.3
Lambin, P.4
Koumenis, C.5
-
23
-
-
34250205154
-
Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia
-
M. Koritzinsky, K.M. Rouschop, and T. van den Beucken Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia Radiother Oncol 83 2007 353 361
-
(2007)
Radiother Oncol
, vol.83
, pp. 353-361
-
-
Koritzinsky, M.1
Rouschop, K.M.2
Van Den Beucken, T.3
-
24
-
-
0026561063
-
A novel quasi-viral agent, MaTu, is a two-component system
-
S. Pastorekova, Z. Zavadova, M. Kostal, O. Babusikova, and J. Zavada A novel quasi-viral agent, MaTu, is a two-component system Virology 187 1992 620 626
-
(1992)
Virology
, vol.187
, pp. 620-626
-
-
Pastorekova, S.1
Zavadova, Z.2
Kostal, M.3
Babusikova, O.4
Zavada, J.5
-
25
-
-
84864003904
-
Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: Results of a phase III randomized trial
-
G.O. Janssens, S.E. Rademakers, and C.H. Terhaard Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial J Clin Oncol 30 2012 1777 1783
-
(2012)
J Clin Oncol
, vol.30
, pp. 1777-1783
-
-
Janssens, G.O.1
Rademakers, S.E.2
Terhaard, C.H.3
-
26
-
-
79960420656
-
Intensive expression of UNC-51-like kinase 1 is a novel biomarker of poor prognosis in patients with esophageal squamous cell carcinoma
-
S. Jiang, Y. Li, and Y.H. Zhu Intensive expression of UNC-51-like kinase 1 is a novel biomarker of poor prognosis in patients with esophageal squamous cell carcinoma Cancer Sci 102 2011 1568 1575
-
(2011)
Cancer Sci
, vol.102
, pp. 1568-1575
-
-
Jiang, S.1
Li, Y.2
Zhu, Y.H.3
-
27
-
-
84857913691
-
The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer
-
M.H. Starmans, K.C. Chu, and S. Haider The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer Radiother Oncol 102 2012 436 443
-
(2012)
Radiother Oncol
, vol.102
, pp. 436-443
-
-
Starmans, M.H.1
Chu, K.C.2
Haider, S.3
-
28
-
-
84875234688
-
PERK/eIF2alpha signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
-
K.M. Rouschop, L.J. Dubois, and T.G. Keulers PERK/eIF2alpha signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS Proc Natl Acad Sci USA 110 2013 4622 4627
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 4622-4627
-
-
Rouschop, K.M.1
Dubois, L.J.2
Keulers, T.G.3
|