메뉴 건너뛰기




Volumn 88, Issue 9, 2003, Pages 1470-1479

Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro

Author keywords

Cell cycle; ECM; G2 arrest; GSK 3 ; ILK; Radiosensitivity

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA1 INTEGRIN; BOVINE SERUM ALBUMIN; CYCLIN D1; FIBRONECTIN; GLYCOGEN SYNTHASE KINASE 3BETA; INTEGRIN; INTEGRIN LINKED KINASE; LAMININ; LIPOCORTIN 5; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; POLYLYSINE; POLYSTYRENE; PROTEIN KINASE B; SCLEROPROTEIN; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0038751716     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600912     Document Type: Article
Times cited : (74)

References (50)
  • 1
    • 0035341495 scopus 로고    scopus 로고
    • Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: Possible involvement of inhibition of survival signal transduction pathways
    • Akimoto T, Nonaka T, Ishikawa H, Sakurai H, Saitoh JI, Takahashi T, Mitsuhashi N (2001) Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. Int J Radiat Oncol Biol Phys 50: 195-201
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 195-201
    • Akimoto, T.1    Nonaka, T.2    Ishikawa, H.3    Sakurai, H.4    Saitoh, J.I.5    Takahashi, T.6    Mitsuhashi, N.7
  • 3
    • 0035872199 scopus 로고    scopus 로고
    • Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • Brognard J, Clark AS, Ni Y, Dennis PA (2001) Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 61: 3986-3997
    • (2001) Cancer Res , vol.61 , pp. 3986-3997
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3    Dennis, P.A.4
  • 4
    • 0027939187 scopus 로고
    • Integrin-mediated cell adhesion activates mitogen-activated protein kinases
    • Chen Q, Kinch MS, Lin TH, Burridge K, Juliano RL (1994) Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J Biol Chem 269: 26602-26605
    • (1994) J Biol Chem , vol.269 , pp. 26602-26605
    • Chen, Q.1    Kinch, M.S.2    Lin, T.H.3    Burridge, K.4    Juliano, R.L.5
  • 5
    • 0036253054 scopus 로고    scopus 로고
    • Ionizing radiation induces up-regulation of functional β1-integrin in lung tumour cell lines in vitro
    • Cordes N, Blaese MA, Meineke V, van Beuningen D (2002) Ionizing radiation induces up-regulation of functional β1-integrin in lung tumour cell lines in vitro. Int J Radiat Biol 78: 347-357
    • (2002) Int J Radiat Biol , vol.78 , pp. 347-357
    • Cordes, N.1    Blaese, M.A.2    Meineke, V.3    Van Beuningen, D.4
  • 6
    • 0038467173 scopus 로고    scopus 로고
    • Fibronectin and laminin increase resistance to ionising radiation and the cytotoxic drug Ukrain® in human tumour and normal cells in vitro
    • in press
    • Cordes N, Blaese MA, Plasswilm L, Rodemann HP, van Beuningen D (2002) Fibronectin and laminin increase resistance to ionising radiation and the cytotoxic drug Ukrain® in human tumour and normal cells in vitro. Int J Radiat Biol, in press
    • (2002) Int J Radiat Biol
    • Cordes, N.1    Blaese, M.A.2    Plasswilm, L.3    Rodemann, H.P.4    Van Beuningen, D.5
  • 7
    • 0038805113 scopus 로고    scopus 로고
    • Cell adhesion-mediated radioresistance (CAM-RR): Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro
    • in press
    • Cordes N, Meineke V (2002) Cell adhesion-mediated radioresistance (CAM-RR): extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro. Strahlenther Onkol, in press
    • (2002) Strahlenther Onkol
    • Cordes, N.1    Meineke, V.2
  • 8
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase 3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase 3 by insulin mediated by protein kinase B. Nature 378: 785-789
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 9
    • 0033105537 scopus 로고    scopus 로고
    • Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines
    • Damiano JS, Cress AE, Hazlehurst LA, Shtil AA, Dalton WS (1999) Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines. Blood 93: 1658-1667
    • (1999) Blood , vol.93 , pp. 1658-1667
    • Damiano, J.S.1    Cress, A.E.2    Hazlehurst, L.A.3    Shtil, A.A.4    Dalton, W.S.5
  • 10
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to an cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME (1997) Akt phosphorylation of BAD couples survival signals to an cell-intrinsic death machinery. Cell 91: 231-241
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 11
    • 0030272735 scopus 로고    scopus 로고
    • Integrin cytoplasmic interactions and bidirectional transmembrane signalling
    • Dedhar S, Hannigan GE (1997) Integrin cytoplasmic interactions and bidirectional transmembrane signalling. Curr Opin Cell Biol 8: 657-669
    • (1997) Curr Opin Cell Biol , vol.8 , pp. 657-669
    • Dedhar, S.1    Hannigan, G.E.2
  • 12
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/Akt by the integrin-linked kinase
    • Delcommenne M, Tan C, Gray V, Ruel L, Woodgett J, Dedhar S (1998) Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/Akt by the integrin-linked kinase. Proc Natl Acad Sci USA 95: 11211-11216
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Ruel, L.4    Woodgett, J.5    Dedhar, S.6
  • 13
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
    • Diehl JA, Cheng M, Roussel MF, Sherr CJ (1998) Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 12: 3499-3511
    • (1998) Genes Dev , vol.12 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 14
    • 0033213954 scopus 로고    scopus 로고
    • Extracellular matrix and radiation G1 cell cycle arrest in human fibroblasts
    • Dimitrijevic-Bussod M, Balzaretti-Maggi VS, Gadbois DM (1999) Extracellular matrix and radiation G1 cell cycle arrest in human fibroblasts. Cancer Res 59: 4843-4847
    • (1999) Cancer Res , vol.59 , pp. 4843-4847
    • Dimitrijevic-Bussod, M.1    Balzaretti-Maggi, V.S.2    Gadbois, D.M.3
  • 15
    • 0032701211 scopus 로고    scopus 로고
    • Effects of the protein kinase inhibitors wortmannin and KN62 on cellular radiosensitivity and radiation-activated S phase and G1/S checkpoints in normal human fibroblasts
    • Enns L, Murray D, Mirzayans R (1999) Effects of the protein kinase inhibitors wortmannin and KN62 on cellular radiosensitivity and radiation-activated S phase and G1/S checkpoints in normal human fibroblasts. Br J Cancer 81: 959-965
    • (1999) Br J Cancer , vol.81 , pp. 959-965
    • Enns, L.1    Murray, D.2    Mirzayans, R.3
  • 16
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H (1994) Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626
    • (1994) J Cell Biol , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 17
    • 1842337424 scopus 로고    scopus 로고
    • Control of radiation-induced G1 arrest by cell-substratum interactions
    • Gadbois DM, Bradbury EM, Lehnert BE (1997) Control of radiation-induced G1 arrest by cell-substratum interactions. Cancer Res 57: 1151-1156
    • (1997) Cancer Res , vol.57 , pp. 1151-1156
    • Gadbois, D.M.1    Bradbury, E.M.2    Lehnert, B.E.3
  • 20
    • 0034618384 scopus 로고    scopus 로고
    • Adhesion to fibronectin via β1-integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR)
    • Hazlehurst LA, Damiano JS, Buyuksal I, Pledger WJ, Dalton WS (2000) Adhesion to fibronectin via β1-integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). Oncogene 19: 4319-4327
    • (2000) Oncogene , vol.19 , pp. 4319-4327
    • Hazlehurst, L.A.1    Damiano, J.S.2    Buyuksal, I.3    Pledger, W.J.4    Dalton, W.S.5
  • 21
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NK-κB activation
    • Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR (2000) Requirement for glycogen synthase kinase-3beta in cell survival and NK-κB activation. Nature 406: 86-90
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 22
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69: 11-25
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 23
    • 0029951444 scopus 로고    scopus 로고
    • Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events
    • Kang JS, Krauss RS (1996) Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events. Mol Cell Biol 16: 3370-3380
    • (1996) Mol Cell Biol , vol.16 , pp. 3370-3380
    • Kang, J.S.1    Krauss, R.S.2
  • 24
    • 0030913673 scopus 로고    scopus 로고
    • Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
    • Khwaja A, Rodriguez-Viciana P, Wennström S, Warne HP, Downward J (1997) Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 16: 2783-2793
    • (1997) EMBO J , vol.16 , pp. 2783-2793
    • Khwaja, A.1    Rodriguez-Viciana, P.2    Wennström, S.3    Warne, H.P.4    Downward, J.5
  • 25
    • 0036113238 scopus 로고    scopus 로고
    • Tumor-associated fibroblasts (part I): Active stromal participants in tumor development and progression?
    • Kunz-Schughart LA, Knuechel R (2002) Tumor-associated fibroblasts (part I): active stromal participants in tumor development and progression? Histol Histopathol 17: 599-621
    • (2002) Histol Histopathol , vol.17 , pp. 599-621
    • Kunz-Schughart, L.A.1    Knuechel, R.2
  • 26
    • 0027109075 scopus 로고
    • p53: Guardian of the genome
    • Lane DP (1992) p53: guardian of the genome. Nature 358: 15-16
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 27
    • 0021997077 scopus 로고
    • Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts
    • Little JB, Nagasawa H (1985) Effect of confluent holding on potentially lethal damage repair, cell cycle progression, and chromosomal aberrations in human normal and ataxia-telangiectasia fibroblasts. Radiat Res 101: 81-93
    • (1985) Radiat Res , vol.101 , pp. 81-93
    • Little, J.B.1    Nagasawa, H.2
  • 28
    • 0032211804 scopus 로고    scopus 로고
    • ECM signalling: Orchestrating cell behaviour and misbehaviour
    • Lukashev ME, Werb Z (1998) ECM signalling: orchestrating cell behaviour and misbehaviour. Trends Cell Biol 8: 437-441
    • (1998) Trends Cell Biol , vol.8 , pp. 437-441
    • Lukashev, M.E.1    Werb, Z.2
  • 30
    • 0037013742 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation
    • Moustakas A, Pardali K, Gaal A, Heldin CH (2002) Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation. Immunol Lett 82: 85-91
    • (2002) Immunol Lett , vol.82 , pp. 85-91
    • Moustakas, A.1    Pardali, K.2    Gaal, A.3    Heldin, C.H.4
  • 31
    • 0037019186 scopus 로고    scopus 로고
    • Distinct roles for phosphoinositide 3-kinase, mitogen-activated protein kinase and p38 MAPK in mediating cell cycle progression of breast cancer cells
    • Neve RM, Holbro T, Hynes NE (2002) Distinct roles for phosphoinositide 3-kinase, mitogen-activated protein kinase and p38 MAPK in mediating cell cycle progression of breast cancer cells. Oncogene 21: 4567-4576
    • (2002) Oncogene , vol.21 , pp. 4567-4576
    • Neve, R.M.1    Holbro, T.2    Hynes, N.E.3
  • 32
    • 0033032591 scopus 로고    scopus 로고
    • Signaling networks - Do all roads lead to the same genes?
    • Pawson T, Saxton TM (1999) Signaling networks - do all roads lead to the same genes? Cell 97: 675-678
    • (1999) Cell , vol.97 , pp. 675-678
    • Pawson, T.1    Saxton, T.M.2
  • 34
    • 0033049815 scopus 로고    scopus 로고
    • The role of laminin-1 in the modulation of radiation damage in endothelial cells and differentiation
    • Rose RW, O'Hara MO, Williamson SK, Grant DS (1999) The role of laminin-1 in the modulation of radiation damage in endothelial cells and differentiation. Radiat Res 152: 14-28
    • (1999) Radiat Res , vol.152 , pp. 14-28
    • Rose, R.W.1    O'Hara, M.O.2    Williamson, S.K.3    Grant, D.S.4
  • 35
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller MD, Parsons JT (1994) Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 6: 705-710
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 705-710
    • Schaller, M.D.1    Parsons, J.T.2
  • 36
    • 0032910337 scopus 로고    scopus 로고
    • Interactions between mitogenic stimuli or, a thousand and one connections
    • Schwartz MA, Baron V (1999) Interactions between mitogenic stimuli or, a thousand and one connections. Curr Opin Cell Biol 11: 197-202
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 197-202
    • Schwartz, M.A.1    Baron, V.2
  • 37
    • 0036229694 scopus 로고    scopus 로고
    • Networks and crosstalk: Integrin signalling spreads
    • Schwartz MA, Ginsberg MH (2002) Networks and crosstalk: integrin signalling spreads. Nat Cell Biol 4: E65-E68
    • (2002) Nat Cell Biol , vol.4
    • Schwartz, M.A.1    Ginsberg, M.H.2
  • 40
    • 0006224409 scopus 로고
    • Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage-independent growth in vitro
    • Shin S-I, Freedman VH, Risser R, Pollack R (1975) Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage-independent growth in vitro. Proc Natl Acad Sci USA 72: 4435-4439
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 4435-4439
    • Shin, S.-I.1    Freedman, V.H.2    Risser, R.3    Pollack, R.4
  • 41
    • 0035889243 scopus 로고    scopus 로고
    • The phosphatidylinositide 3′-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C
    • Tenzer A, Zingg D, Rocha S, Hemmings B, Fabbro D, Glanzmann C, Schubiger PA, Bodis S, Pruschy M (2001) The phosphatidylinositide 3′-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C. Cancer Res 61: 8203-8210
    • (2001) Cancer Res , vol.61 , pp. 8203-8210
    • Tenzer, A.1    Zingg, D.2    Rocha, S.3    Hemmings, B.4    Fabbro, D.5    Glanzmann, C.6    Schubiger, P.A.7    Bodis, S.8    Pruschy, M.9
  • 42
    • 0037025313 scopus 로고    scopus 로고
    • β1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway
    • Tian B, Lessan K, Kahm J, Kleidon J, Henke C (2002) β1 integrin regulates fibroblast viability during collagen matrix contraction through a phosphatidylinositol 3-kinase/Akt/protein kinase B signaling pathway. J Biol Chem 27: 24667-24675
    • (2002) J Biol Chem , vol.27 , pp. 24667-24675
    • Tian, B.1    Lessan, K.2    Kahm, J.3    Kleidon, J.4    Henke, C.5
  • 43
    • 0032746701 scopus 로고    scopus 로고
    • Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner
    • Troussard AA, Tan C, Yoganathan TN, Dedhar S (1999) Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner. Mol Cell Biol 19: 7420-7427
    • (1999) Mol Cell Biol , vol.19 , pp. 7420-7427
    • Troussard, A.A.1    Tan, C.2    Yoganathan, T.N.3    Dedhar, S.4
  • 44
    • 0018879097 scopus 로고
    • Morphological appearance, growth behaviour and migratory activity of human tumor cells maintained on extracellular matrix vs plastic
    • Vlodavsky I, Lui GM, Gospodarowicz D (1980) Morphological appearance, growth behaviour and migratory activity of human tumor cells maintained on extracellular matrix vs plastic. Cell 19: 607-616
    • (1980) Cell , vol.19 , pp. 607-616
    • Vlodavsky, I.1    Lui, G.M.2    Gospodarowicz, D.3
  • 46
    • 0035950544 scopus 로고    scopus 로고
    • Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice
    • White DE, Cardiff RD, Dedhar S, Muller WJ (2001) Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. Oncogene 20: 7064-7072
    • (2001) Oncogene , vol.20 , pp. 7064-7072
    • White, D.E.1    Cardiff, R.D.2    Dedhar, S.3    Muller, W.J.4
  • 48
    • 0030613633 scopus 로고    scopus 로고
    • Activation of p53-p21waf1 pathway in response to disruption of cell-matrix interactions
    • Wu RC, Schönthal AH (1997) Activation of p53-p21waf1 pathway in response to disruption of cell-matrix interactions. J Biol Chem 272: 29091-29098
    • (1997) J Biol Chem , vol.272 , pp. 29091-29098
    • Wu, R.C.1    Schönthal, A.H.2
  • 49
    • 0036229695 scopus 로고    scopus 로고
    • Integrin regulation of growth factor receptors
    • Yamada KM, Even-Ram S (2002) Integrin regulation of growth factor receptors. Nat Cell Biol 4: E75-E76
    • (2002) Nat Cell Biol , vol.4
    • Yamada, K.M.1    Even-Ram, S.2
  • 50
    • 0029876639 scopus 로고    scopus 로고
    • Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
    • Zhu X, Ohtsubo M, Bohmer RM, Roberts JM, Assoian RK (1996) Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J Cell Biol 133: 391-403
    • (1996) J Cell Biol , vol.133 , pp. 391-403
    • Zhu, X.1    Ohtsubo, M.2    Bohmer, R.M.3    Roberts, J.M.4    Assoian, R.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.