메뉴 건너뛰기




Volumn 108, Issue 3, 2013, Pages 506-510

Hypoxia and metastasis in an orthotopic cervix cancer xenograft model

Author keywords

Cervix; CXCR4; Cyclic hypoxia; Hedgehog; Metastasis

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; PLERIXAFOR; SHORT HAIRPIN RNA;

EID: 84887019324     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.06.019     Document Type: Article
Times cited : (19)

References (33)
  • 1
    • 79960344338 scopus 로고    scopus 로고
    • Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - A systematic review and meta-analysis
    • J. Overgaard Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - a systematic review and meta-analysis Radiother Oncol 100 2011 22 32
    • (2011) Radiother Oncol , vol.100 , pp. 22-32
    • Overgaard, J.1
  • 2
    • 84868374271 scopus 로고    scopus 로고
    • Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo
    • X. Sun, L. Xing, and X. Deng Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo Radiother Oncol 105 2012 57 63
    • (2012) Radiother Oncol , vol.105 , pp. 57-63
    • Sun, X.1    Xing, L.2    Deng, X.3
  • 3
    • 84857913691 scopus 로고    scopus 로고
    • The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer
    • M.H. Starmans, K.C. Chu, and S. Haider The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer Radiother Oncol 102 2012 436 443
    • (2012) Radiother Oncol , vol.102 , pp. 436-443
    • Starmans, M.H.1    Chu, K.C.2    Haider, S.3
  • 4
    • 84455209531 scopus 로고    scopus 로고
    • Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck
    • K. Toustrup, B.S. Sorensen, and P. Lassen Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck Radiother Oncol 102 2012 122 129
    • (2012) Radiother Oncol , vol.102 , pp. 122-129
    • Toustrup, K.1    Sorensen, B.S.2    Lassen, P.3
  • 5
    • 84867560542 scopus 로고    scopus 로고
    • Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI
    • C. Halle, E. Andersen, and M. Lando Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI Cancer Res 72 2012 5285 5295
    • (2012) Cancer Res , vol.72 , pp. 5285-5295
    • Halle, C.1    Andersen, E.2    Lando, M.3
  • 6
    • 48649095925 scopus 로고    scopus 로고
    • The pervasive presence of fluctuating oxygenation in tumors
    • L.I. Cardenas-Navia, D. Mace, and R.A. Richardson The pervasive presence of fluctuating oxygenation in tumors Cancer Res 68 2008 5812 5819
    • (2008) Cancer Res , vol.68 , pp. 5812-5819
    • Cardenas-Navia, L.I.1    Mace, D.2    Richardson, R.A.3
  • 7
    • 27944473896 scopus 로고    scopus 로고
    • Fluctuations in po2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy
    • K.G. Brurberg, H.K. Skogmo, B.A. Graff, D.R. Olsen, and E.K. Rofstad Fluctuations in po2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy Radiother Oncol 77 2005 220 226
    • (2005) Radiother Oncol , vol.77 , pp. 220-226
    • Brurberg, K.G.1    Skogmo, H.K.2    Graff, B.A.3    Olsen, D.R.4    Rofstad, E.K.5
  • 8
    • 58949092790 scopus 로고    scopus 로고
    • The tumor microenvironment and metastatic disease
    • S.J. Lunt, N. Chaudary, and R.P. Hill The tumor microenvironment and metastatic disease Clin Exp Metastasis 26 2009 19 34
    • (2009) Clin Exp Metastasis , vol.26 , pp. 19-34
    • Lunt, S.J.1    Chaudary, N.2    Hill, R.P.3
  • 10
    • 0035893396 scopus 로고    scopus 로고
    • Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors
    • R.A. Cairns, T. Kalliomaki, and R.P. Hill Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors Cancer Res 61 2001 8903 8908
    • (2001) Cancer Res , vol.61 , pp. 8903-8908
    • Cairns, R.A.1    Kalliomaki, T.2    Hill, R.P.3
  • 11
    • 1542405875 scopus 로고    scopus 로고
    • Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma
    • R.A. Cairns, and R.P. Hill Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma Cancer Res 64 2004 2054 2061
    • (2004) Cancer Res , vol.64 , pp. 2054-2061
    • Cairns, R.A.1    Hill, R.P.2
  • 12
    • 34247541997 scopus 로고    scopus 로고
    • Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis
    • E.K. Rofstad, K. Galappathi, B. Mathiesen, and E.B. Ruud Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis Clin Cancer Res 13 2007 1971 1978
    • (2007) Clin Cancer Res , vol.13 , pp. 1971-1978
    • Rofstad, E.K.1    Galappathi, K.2    Mathiesen, B.3    Ruud, E.B.4
  • 13
    • 0036467638 scopus 로고    scopus 로고
    • Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer
    • A. Fyles, M. Milosevic, and D. Hedley Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer J Clin Oncol 20 2002 680 687
    • (2002) J Clin Oncol , vol.20 , pp. 680-687
    • Fyles, A.1    Milosevic, M.2    Hedley, D.3
  • 14
    • 65649136924 scopus 로고    scopus 로고
    • Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors
    • N. Chaudary, and R.P. Hill Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors Lab Invest 89 2009 587 596
    • (2009) Lab Invest , vol.89 , pp. 587-596
    • Chaudary, N.1    Hill, R.P.2
  • 15
    • 84861875422 scopus 로고    scopus 로고
    • Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation
    • N. Chaudary, M. Pintilie, and D. Hedley Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation Cancer 118 2012 3105 3115
    • (2012) Cancer , vol.118 , pp. 3105-3115
    • Chaudary, N.1    Pintilie, M.2    Hedley, D.3
  • 16
    • 84255209278 scopus 로고    scopus 로고
    • Orthotopic xenograft model of cervical cancer for studying microenvironmental effects on metastasis formation and response to drug treatment
    • N. Chaudary, D.W. Hedley, and R.P. Hill Orthotopic xenograft model of cervical cancer for studying microenvironmental effects on metastasis formation and response to drug treatment Curr Protoc Pharmacol 2011 14.19.1 14.19.11
    • (2011) Curr Protoc Pharmacol , pp. 14191-141911
    • Chaudary, N.1    Hedley, D.W.2    Hill, R.P.3
  • 17
    • 84866917935 scopus 로고    scopus 로고
    • Characterization of the tumor microenvironment in patient-derived cervix xenografts (OCICx)
    • N. Chaudary, M. Pintilie, J. Schwock, N. Dhani, B. Clarke, and M. Milosevic Characterization of the tumor microenvironment in patient-derived cervix xenografts (OCICx) Cancer 4 2012 821 845
    • (2012) Cancer , vol.4 , pp. 821-845
    • Chaudary, N.1    Pintilie, M.2    Schwock, J.3    Dhani, N.4    Clarke, B.5    Milosevic, M.6
  • 18
    • 33751549095 scopus 로고    scopus 로고
    • Targeting the hedgehog pathway in cancer
    • L.L. Rubin, and F.J. de Sauvage Targeting the hedgehog pathway in cancer Nat Rev Drug Discov 5 2006 1026 1033
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 1026-1033
    • Rubin, L.L.1    De Sauvage, F.J.2
  • 19
    • 52149119128 scopus 로고    scopus 로고
    • A paracrine requirement for hedgehog signalling in cancer
    • R.L. Yauch, S.E. Gould, and S.J. Scales A paracrine requirement for hedgehog signalling in cancer Nature 455 2008 406 410
    • (2008) Nature , vol.455 , pp. 406-410
    • Yauch, R.L.1    Gould, S.E.2    Scales, S.J.3
  • 20
    • 84876664218 scopus 로고    scopus 로고
    • Tumor-stroma interaction in orthotopic primary pancreatic cancer xenografts during hedgehog pathway inhibition
    • Q. Chang, W.D. Foltz, N. Chaudary, R.P. Hill, and D.W. Hedley Tumor-stroma interaction in orthotopic primary pancreatic cancer xenografts during hedgehog pathway inhibition Int J Cancer 133 2013 225 234
    • (2013) Int J Cancer , vol.133 , pp. 225-234
    • Chang, Q.1    Foltz, W.D.2    Chaudary, N.3    Hill, R.P.4    Hedley, D.W.5
  • 21
    • 81155161029 scopus 로고    scopus 로고
    • Suppression of vascular endothelial growth factor receptor 3 (VEGFR3) and vascular endothelial growth factor C (VEGFC) inhibits hypoxia-induced lymph node metastases in cervix cancer
    • N. Chaudary, M. Milosevic, and R.P. Hill Suppression of vascular endothelial growth factor receptor 3 (VEGFR3) and vascular endothelial growth factor C (VEGFC) inhibits hypoxia-induced lymph node metastases in cervix cancer Gynecol Oncol 123 2011 393 400
    • (2011) Gynecol Oncol , vol.123 , pp. 393-400
    • Chaudary, N.1    Milosevic, M.2    Hill, R.P.3
  • 22
    • 77953090345 scopus 로고    scopus 로고
    • CXCL12 (SDF-1)/CXCR4 pathway in cancer
    • B.A. Teicher, and S.P. Fricker CXCL12 (SDF-1)/CXCR4 pathway in cancer Clin Cancer Res 16 2010 2927 2931
    • (2010) Clin Cancer Res , vol.16 , pp. 2927-2931
    • Teicher, B.A.1    Fricker, S.P.2
  • 23
    • 78449300594 scopus 로고    scopus 로고
    • CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression
    • X. Sun, G. Cheng, and M. Hao CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression Cancer Metastasis Rev 29 2010 709 722
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 709-722
    • Sun, X.1    Cheng, G.2    Hao, M.3
  • 24
    • 33947275735 scopus 로고    scopus 로고
    • Study on CXCR4/SDF-1alpha axis in lymph node metastasis of cervical squamous cell carcinoma
    • J.P. Zhang, W.G. Lu, and F. Ye Study on CXCR4/SDF-1alpha axis in lymph node metastasis of cervical squamous cell carcinoma Int J Gynecol Cancer 17 2007 478 483
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 478-483
    • Zhang, J.P.1    Lu, W.G.2    Ye, F.3
  • 25
    • 34248363901 scopus 로고    scopus 로고
    • CXCR4 expression is associated with pelvic lymph node metastasis in cervical adenocarcinoma
    • Y.C. Yang, Z.Y. Lee, and C.C. Wu CXCR4 expression is associated with pelvic lymph node metastasis in cervical adenocarcinoma Int J Gynecol Cancer 17 2007 676 686
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 676-686
    • Yang, Y.C.1    Lee, Z.Y.2    Wu, C.C.3
  • 26
    • 33846544434 scopus 로고    scopus 로고
    • Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer
    • J. Kodama, Hasengaowa, and T. Kusumoto Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer Ann Oncol 18 2007 70 76
    • (2007) Ann Oncol , vol.18 , pp. 70-76
    • Kodama, J.1    Hasengaowa2    Kusumoto, T.3
  • 27
    • 77949697909 scopus 로고    scopus 로고
    • Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
    • M. Kioi, H. Vogel, and G. Schultz Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice J Clin Invest 120 2010 694 705
    • (2010) J Clin Invest , vol.120 , pp. 694-705
    • Kioi, M.1    Vogel, H.2    Schultz, G.3
  • 28
    • 58249100053 scopus 로고    scopus 로고
    • CXCR4 antagonists: Targeting the microenvironment in leukemia and other cancers
    • J.A. Burger, and A. Peled CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers Leukemia 23 2009 43 52
    • (2009) Leukemia , vol.23 , pp. 43-52
    • Burger, J.A.1    Peled, A.2
  • 29
    • 77957784479 scopus 로고    scopus 로고
    • Activation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxia
    • G. Wang, Z. Zhang, and Z. Xu Activation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxia Biochim Biophys Acta 1803 2011 1359 1367
    • (2011) Biochim Biophys Acta , vol.1803 , pp. 1359-1367
    • Wang, G.1    Zhang, Z.2    Xu, Z.3
  • 30
    • 79956219871 scopus 로고    scopus 로고
    • Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer
    • H. Onishi, M. Kai, and S. Odate Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer Cancer Sci 102 2011 1144 1150
    • (2011) Cancer Sci , vol.102 , pp. 1144-1150
    • Onishi, H.1    Kai, M.2    Odate, S.3
  • 31
    • 33751285537 scopus 로고    scopus 로고
    • Hedgehog: An attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response
    • J. Sims-Mourtada, J.G. Izzo, and S. Apisarnthanarax Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response Clin Cancer Res 12 2006 6565 6572
    • (2006) Clin Cancer Res , vol.12 , pp. 6565-6572
    • Sims-Mourtada, J.1    Izzo, J.G.2    Apisarnthanarax, S.3
  • 32
    • 43649094590 scopus 로고    scopus 로고
    • Hedgehog signal activation in oesophageal cancer patients undergoing neoadjuvant chemoradiotherapy
    • R. Yoshikawa, Y. Nakano, and L. Tao Hedgehog signal activation in oesophageal cancer patients undergoing neoadjuvant chemoradiotherapy Br J Cancer 98 2008 1670 1674
    • (2008) Br J Cancer , vol.98 , pp. 1670-1674
    • Yoshikawa, R.1    Nakano, Y.2    Tao, L.3
  • 33
    • 79952387584 scopus 로고    scopus 로고
    • Correlation of hedgehog signal activation with chemoradiotherapy sensitivity and survival in esophageal squamous cell carcinomas
    • W. Zhu, Z. You, and T. Li Correlation of hedgehog signal activation with chemoradiotherapy sensitivity and survival in esophageal squamous cell carcinomas Jpn J Clin Oncol 41 2011 386 393
    • (2011) Jpn J Clin Oncol , vol.41 , pp. 386-393
    • Zhu, W.1    You, Z.2    Li, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.