-
1
-
-
36949005417
-
DNA damage signalling guards against activated oncogenes and tumour progression
-
DOI 10.1038/sj.onc.1210881, PII 1210881
-
J. Bartek, J. Bartkova, and J. Lukas DNA damage signalling guards against activated oncogenes and tumour progression Oncogene 26 2007 7773 7779 (Pubitemid 350242463)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7773-7779
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
2
-
-
69749095427
-
Checkpoint signaling from a single DNA interstrand crosslink
-
M. Ben-Yehoyada, L.C. Wang, I.D. Kozekov, C.J. Rizzo, M.E. Gottesman, and J. Gautier Checkpoint signaling from a single DNA interstrand crosslink Mol Cell 35 2009 704 715
-
(2009)
Mol Cell
, vol.35
, pp. 704-715
-
-
Ben-Yehoyada, M.1
Wang, L.C.2
Kozekov, I.D.3
Rizzo, C.J.4
Gottesman, M.E.5
Gautier, J.6
-
3
-
-
0033378084
-
Oxidative damage, bleomycin, and gamma radiation induce different types of DNA strand breaks in normal lymphocytes and thymocytes. A comet assay study
-
L. Benitez-Bribiesca, and P. Sanchez-Suarez Oxidative damage, bleomycin, and gamma radiation induce different types of DNA strand breaks in normal lymphocytes and thymocytes. A comet assay study Ann NY Acad Sci 887 1999 133 149 (Pubitemid 30040225)
-
(1999)
Annals of the New York Academy of Sciences
, vol.887
, pp. 133-149
-
-
Benitez-Bribiesca, L.1
Sanchez-Suarez, P.2
-
4
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
DOI 10.1038/nrm2351, PII NRM2351
-
D. Branzei, and M. Foiani Regulation of DNA repair throughout the cell cycle Nat Rev Mol Cell Biol 9 2008 297 308 (Pubitemid 351430844)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.4
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
5
-
-
34250343422
-
Homologous recombination and prostate cancer: A model for novel DNA repair targets and therapies
-
DOI 10.1016/j.radonc.2007.04.016, PII S0167814007001569, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
-
R.G. Bristow, H. Ozcelik, F. Jalali, N. Chan, and D. Vesprini Homologous recombination and prostate cancer: a model for novel DNA repair targets and therapies Radiother Oncol 83 2007 220 230 (Pubitemid 46915541)
-
(2007)
Radiotherapy and Oncology
, vol.83
, Issue.3
, pp. 220-230
-
-
Bristow, R.G.1
Ozcelik, H.2
Jalali, F.3
Chan, N.4
Vesprini, D.5
-
6
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
DOI 10.1038/nature03443
-
H.E. Bryant, N. Schultz, and H.D. Thomas Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase Nature 434 2005 913 917 (Pubitemid 40559005)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
7
-
-
77956487620
-
Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets
-
A.J. Chalmers, M. Lakshman, N. Chan, and R.G. Bristow Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets Semin Radiat Oncol 20 2010 274 281
-
(2010)
Semin Radiat Oncol
, vol.20
, pp. 274-281
-
-
Chalmers, A.J.1
Lakshman, M.2
Chan, N.3
Bristow, R.G.4
-
8
-
-
34547814092
-
Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells
-
DOI 10.1091/mbc.E06-08-0689
-
C. Conti, B. Sacca, J. Herrick, C. Lalou, Y. Pommier, and A. Bensimon Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells Mol Biol Cell 18 2007 3059 3067 (Pubitemid 47235311)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.8
, pp. 3059-3067
-
-
Conti, C.1
Sacca, B.2
Herrick, J.3
Lalou, C.4
Pommier, Y.5
Bensimon, A.6
-
9
-
-
68849126662
-
Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90
-
F.A. Dungey, K.W. Caldecott, and A.J. Chalmers Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90 Mol Cancer Ther 8 2009 2243 2254
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2243-2254
-
-
Dungey, F.A.1
Caldecott, K.W.2
Chalmers, A.J.3
-
10
-
-
54049112348
-
Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: Mechanisms and therapeutic potential
-
F.A. Dungey, D.A. Loser, and A.J. Chalmers Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential Int J Radiat Oncol Biol Phys 72 2008 1188 1197
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.72
, pp. 1188-1197
-
-
Dungey, F.A.1
Loser, D.A.2
Chalmers, A.J.3
-
11
-
-
70349912086
-
Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells
-
R.A. Frum, Z.S. Khondker, and D.G. Kaufman Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells Cell Cycle 8 2009 3133 3148
-
(2009)
Cell Cycle
, vol.8
, pp. 3133-3148
-
-
Frum, R.A.1
Khondker, Z.S.2
Kaufman, D.G.3
-
12
-
-
79960341240
-
ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells
-
S.M. Harding, C. Coackley, and R.G. Bristow ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells Radiother Oncol 99 2011 307 312
-
(2011)
Radiother Oncol
, vol.99
, pp. 307-312
-
-
Harding, S.M.1
Coackley, C.2
Bristow, R.G.3
-
13
-
-
77955505023
-
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response
-
M. Huang, J.M. Kim, B. Shiotani, K. Yang, L. Zou, and A.D. D'Andrea The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response Mol Cell 39 2010 259 268
-
(2010)
Mol Cell
, vol.39
, pp. 259-268
-
-
Huang, M.1
Kim, J.M.2
Shiotani, B.3
Yang, K.4
Zou, L.5
D'Andrea, A.D.6
-
14
-
-
0032559794
-
Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
-
DOI 10.1083/jcb.140.6.1285
-
D.A. Jackson, and A. Pombo Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells J Cell Biol 140 1998 1285 1295 (Pubitemid 28152979)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.6
, pp. 1285-1295
-
-
Jackson, D.A.1
Pombo, A.2
-
15
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
DOI 10.1038/ncb1337, PII N1337
-
A. Jazayeri, J. Falck, and C. Lukas ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks Nat Cell Biol 8 2006 37 45 (Pubitemid 43064795)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.1
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.M.5
Lukas, J.6
Jackson, S.P.7
-
16
-
-
80655127826
-
The role of homologous recombination in radiation-induced double-strand break repair
-
P.A. Jeggo, V. Geuting, and M. Lobrich The role of homologous recombination in radiation-induced double-strand break repair Radiother Oncol 101 2011 7 12
-
(2011)
Radiother Oncol
, vol.101
, pp. 7-12
-
-
Jeggo, P.A.1
Geuting, V.2
Lobrich, M.3
-
17
-
-
0026347496
-
Cytotoxicity and DNA crosslinks produced by mitomycin analogs in aerobic and hypoxic EMT6 cells
-
S.R. Keyes, R. Loomis, M.P. DiGiovanna, C.A. Pritsos, S. Rockwell, and A.C. Sartorelli Cytotoxicity and DNA crosslinks produced by mitomycin analogs in aerobic and hypoxic EMT6 cells Cancer Commun 3 1991 351 356
-
(1991)
Cancer Commun
, vol.3
, pp. 351-356
-
-
Keyes, S.R.1
Loomis, R.2
Digiovanna, M.P.3
Pritsos, C.A.4
Rockwell, S.5
Sartorelli, A.C.6
-
18
-
-
28444433678
-
The two edges of the ATM sword: Co-operation between repair and checkpoint functions
-
DOI 10.1016/j.radonc.2005.06.027, PII S0167814005002719
-
M. Lobrich, and P.A. Jeggo The two edges of the ATM sword: co-operation between repair and checkpoint functions Radiother Oncol 76 2005 112 118 (Pubitemid 41725435)
-
(2005)
Radiotherapy and Oncology
, vol.76
, Issue.2
, pp. 112-118
-
-
Lobrich, M.1
Jeggo, P.A.2
-
19
-
-
34247257202
-
The structural determinants of checkpoint activation
-
DOI 10.1101/gad.1522607
-
C.A. MacDougall, T.S. Byun, C. Van, M.C. Yee, and K.A. Cimprich The structural determinants of checkpoint activation Genes Dev 21 2007 898 903 (Pubitemid 46625639)
-
(2007)
Genes and Development
, vol.21
, Issue.8
, pp. 898-903
-
-
MacDougall, C.A.1
Byun, T.S.2
Van, C.3
Yee, M.-C.4
Cimprich, K.A.5
-
20
-
-
34250010317
-
Chk1 regulates the density of active replication origins during the vertebrate S phase
-
DOI 10.1038/sj.emboj.7601714, PII 7601714
-
A. Maya-Mendoza, E. Petermann, D.A. Gillespie, K.W. Caldecott, and D.A. Jackson Chk1 regulates the density of active replication origins during the vertebrate S phase EMBO J 26 2007 2719 2731 (Pubitemid 46884282)
-
(2007)
EMBO Journal
, vol.26
, Issue.11
, pp. 2719-2731
-
-
Maya-Mendoza, A.1
Petermann, E.2
Gillespie, D.A.F.3
Caldecott, K.W.4
Jackson, D.A.5
-
21
-
-
2442582392
-
Visualization of altered replication dynamics after DNA damage in human cells
-
DOI 10.1074/jbc.M400022200
-
C.J. Merrick, D. Jackson, and J.F. Diffley Visualization of altered replication dynamics after DNA damage in human cells J Biol Chem 279 2004 20067 20075 (Pubitemid 38623451)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 20067-20075
-
-
Merrick, C.J.1
Jackson, D.2
Diffley, J.F.X.3
-
22
-
-
77953770987
-
Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair
-
M.A. Morgan, L.A. Parsels, and L. Zhao Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair Cancer Res 70 2010 4972 4981
-
(2010)
Cancer Res
, vol.70
, pp. 4972-4981
-
-
Morgan, M.A.1
Parsels, L.A.2
Zhao, L.3
-
23
-
-
79960359070
-
The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy
-
S. Nowsheen, J.A. Bonner, and E.S. Yang The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy Radiother Oncol 99 2011 331 338
-
(2011)
Radiother Oncol
, vol.99
, pp. 331-338
-
-
Nowsheen, S.1
Bonner, J.A.2
Yang, E.S.3
-
24
-
-
33645825609
-
Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase
-
E. Petermann, A. Maya-Mendoza, G. Zachos, D.A. Gillespie, D.A. Jackson, and K.W. Caldecott Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase Mol Cell Biol 26 2006 3319 3326
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3319-3326
-
-
Petermann, E.1
Maya-Mendoza, A.2
Zachos, G.3
Gillespie, D.A.4
Jackson, D.A.5
Caldecott, K.W.6
-
25
-
-
34547132330
-
Endogenous γ-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase-deficient cells is related to DNA replication arrested forks
-
DOI 10.1158/1541-7786.MCR-07-0028
-
V.A. Rao, C. Conti, and J. Guirouilh-Barbat Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks Mol Cancer Res 5 2007 713 724 (Pubitemid 47105490)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.7
, pp. 713-724
-
-
Rao, V.A.1
Conti, C.2
Guirouilh-Barbat, J.3
Nakamura, A.4
Miao, Z.-H.5
Davies, S.L.6
Sacca, B.7
Hickson, I.D.8
Bensimon, A.9
Pommier, Y.10
-
26
-
-
4644224492
-
Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: A therapeutic strategy in tumor cell radiosensitization?
-
DOI 10.1016/j.radonc.2004.07.002, PII S0167814004002944
-
A.H. Ree, A. Bratland, R.V. Nome, T. Stokke, O. Fodstad, and Y. Andersson Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization? Radiother Oncol 72 2004 305 310 (Pubitemid 39265384)
-
(2004)
Radiotherapy and Oncology
, vol.72
, Issue.3
, pp. 305-310
-
-
Ree, A.H.1
Bratland, A.2
Nome, R.V.3
Stokke, T.4
Fodstad, O.5
Andersson, Y.6
-
27
-
-
79960378407
-
Molecular and translational radiation biology/oncology: What's up?
-
H.P. Rodemann, and B.G. Wouters Molecular and translational radiation biology/oncology: what's up? Radiother Oncol 99 2011 257 261
-
(2011)
Radiother Oncol
, vol.99
, pp. 257-261
-
-
Rodemann, H.P.1
Wouters, B.G.2
-
28
-
-
23344444636
-
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
-
DOI 10.1128/MCB.25.16.7158-7169.2005
-
N. Saleh-Gohari, H.E. Bryant, N. Schultz, K.M. Parker, T.N. Cassel, and T. Helleday Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks Mol Cell Biol 25 2005 7158 7169 (Pubitemid 41105912)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.16
, pp. 7158-7169
-
-
Saleh-Gohari, N.1
Bryant, H.E.2
Schultz, N.3
Parker, K.M.4
Cassel, T.N.5
Helleday, T.6
-
29
-
-
0742305875
-
Repairing DNA-methylation damage
-
DOI 10.1038/nrm1312
-
B. Sedgwick Repairing DNA-methylation damage Nat Rev Mol Cell Biol 5 2004 148 157 (Pubitemid 38160257)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.2
, pp. 148-157
-
-
Sedgwick, B.1
-
30
-
-
34547902426
-
The intra-S-phase checkpoint affects both DNA replication initiation and elongation: Single-cell and -DNA fiber analyses
-
DOI 10.1128/MCB.02278-06
-
J.A. Seiler, C. Conti, A. Syed, M.I. Aladjem, and Y. Pommier The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses Mol Cell Biol 27 2007 5806 5818 (Pubitemid 47257835)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.16
, pp. 5806-5818
-
-
Seiler, J.A.1
Conti, C.2
Syed, A.3
Aladjem, M.I.4
Pommier, Y.5
-
31
-
-
0037180432
-
The mechanism of topoisomerase I poisoning by a camptothecin analog
-
DOI 10.1073/pnas.242259599
-
B.L. Staker, K. Hjerrild, M.D. Feese, C.A. Behnke, A.B. Burgin Jr., and L. Stewart The mechanism of topoisomerase I poisoning by a camptothecin analog Proc Natl Acad Sci USA 99 2002 15387 15392 (Pubitemid 35403944)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.24
, pp. 15387-15392
-
-
Staker, B.L.1
Hjerrild, K.2
Feese, M.D.3
Behnke, C.A.4
Burgin Jr., A.B.5
Stewart, L.6
-
32
-
-
0037182814
-
A modified neutral comet assay: Elimination of lysis at high temperature and validation of the assay with anti-single-stranded DNA antibody
-
DOI 10.1016/S1383-5718(02)00070-0, PII S1383571802000700
-
M. Wojewodzka, I. Buraczewska, and M. Kruszewski A modified neutral comet assay: elimination of lysis at high temperature and validation of the assay with anti-single-stranded DNA antibody Mutat Res 518 2002 9 20 (Pubitemid 34626841)
-
(2002)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.518
, Issue.1
, pp. 9-20
-
-
Wojewodzka, M.1
Buraczewska, I.2
Kruszewski, M.3
-
33
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
DOI 10.1126/science.1083430
-
L. Zou, and S.J. Elledge DNA sensing damage through ATRIP recognition of RPA-ssDNA complexes Science 300 2003 1542 1548 (Pubitemid 36682880)
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
|