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Volumn 19, Issue 18, 2013, Pages 5202-5209

TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: Implications for fusion status anddsb repair

(20)  Pra, Alan Dal a,b   Lalonde, Emilie a,c   Sykes, Jenna a   Warde, Fiona a,b   Ishkanian, Adrian a,b   Meng, Alice a   Maloff, Chad d   Srigley, John f   Joshua, Anthony M a   Petrovics, Gyorgy g   Van Der Kwast, Theodorus a   Evans, Andrew a   Milosevic, Michael a,b   Saad, Fred h   Collins, Colin e   Squire, Jeremy i   Lam, Wan d   Bismar, Tarek A j   Boutros, Paul C a,c   Bristow, Robert G a,b  


Author keywords

[No Author keywords available]

Indexed keywords

ANTIANDROGEN; DNA; PROSTATE SPECIFIC ANTIGEN; TRANSCRIPTION FACTOR ERG;

EID: 84884580486     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-1049     Document Type: Article
Times cited : (41)

References (48)
  • 1
  • 2
    • 68149159298 scopus 로고    scopus 로고
    • ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
    • Zong Y, Xin L, Goldstein AS, Lawson DA, Teitell MA, Witte ON. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc Natl Acad Sci U S A 2009;106:12465-70.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12465-12470
    • Zong, Y.1    Xin, L.2    Goldstein, A.S.3    Lawson, D.A.4    Teitell, M.A.5    Witte, O.N.6
  • 3
    • 77956290679 scopus 로고    scopus 로고
    • FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-tomesenchymal transition in human prostate cancer cells
    • Gupta S, Iljin K, Sara H, Mpindi JP, Mirtti T, Vainio P, et al. FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-tomesenchymal transition in human prostate cancer cells. Cancer Res 2010;70:6735-45.
    • (2010) Cancer Res , vol.70 , pp. 6735-6745
    • Gupta, S.1    Iljin, K.2    Sara, H.3    Mpindi, J.P.4    Mirtti, T.5    Vainio, P.6
  • 4
    • 51649115957 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation
    • Sun C, Dobi A, Mohamed A, Li H, Thangapazham RL, Furusato B, et al. TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene 2008;27:5348-53.
    • (2008) Oncogene , vol.27 , pp. 5348-5353
    • Sun, C.1    Dobi, A.2    Mohamed, A.3    Li, H.4    Thangapazham, R.L.5    Furusato, B.6
  • 5
    • 80053078529 scopus 로고    scopus 로고
    • Common gene rearrangements in prostate cancer
    • Rubin MA, Maher CA, Chinnaiyan AM. Common gene rearrangements in prostate cancer. J Clin Oncol 2011;29:3659-68.
    • (2011) J Clin Oncol , vol.29 , pp. 3659-3668
    • Rubin, M.A.1    Maher, C.A.2    Chinnaiyan, A.M.3
  • 6
    • 56649091295 scopus 로고    scopus 로고
    • Absence of TMPRSS2: ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
    • Yoshimoto M, Joshua AM, Cunha IW, Coudry RA, Fonseca FP, Ludkovski O, et al. Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome. Mod Pathol 2008;21:1451-60.
    • (2008) Mod Pathol , vol.21 , pp. 1451-1460
    • Yoshimoto, M.1    Joshua, A.M.2    Cunha, I.W.3    Coudry, R.A.4    Fonseca, F.P.5    Ludkovski, O.6
  • 7
    • 80855124842 scopus 로고    scopus 로고
    • ERG gene rearrangement status in prostate cancer detected by immunohistochemistry
    • Falzarano SM, Zhou M, Carver P, Tsuzuki T, Simmerman K, He H, et al. ERG gene rearrangement status in prostate cancer detected by immunohistochemistry. Virchows Arch 2011;459:441-7.
    • (2011) Virchows Arch , vol.459 , pp. 441-447
    • Falzarano, S.M.1    Zhou, M.2    Carver, P.3    Tsuzuki, T.4    Simmerman, K.5    He, H.6
  • 11
    • 23844519987 scopus 로고    scopus 로고
    • Optimal treatment of intermediaterisk prostate carcinoma with radiotherapy: Clinical and translational issues
    • Nichol AM, Warde P, Bristow RG. Optimal treatment of intermediaterisk prostate carcinoma with radiotherapy: clinical and translational issues. Cancer 2005;104:891-905.
    • (2005) Cancer , vol.104 , pp. 891-905
    • Nichol, A.M.1    Warde, P.2    Bristow, R.G.3
  • 12
    • 84862952700 scopus 로고    scopus 로고
    • Comparative analysis of prostate-specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy. Results from the Prostate Cancer Results Study Group
    • Grimm P, Billiet I, Bostwick D, Dicker AP, Frank S, Immerzeel J, et al. Comparative analysis of prostate-specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy. Results from the Prostate Cancer Results Study Group. BJU Int 2012;109 Suppl 1:22-9.
    • (2012) BJU Int , vol.109 , Issue.SUPPL. 1 , pp. 22-29
    • Grimm, P.1    Billiet, I.2    Bostwick, D.3    Dicker, A.P.4    Frank, S.5    Immerzeel, J.6
  • 13
    • 34248510706 scopus 로고    scopus 로고
    • TMPRSS2: ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
    • Demichelis F, Fall K, Perner S, Andren O, Schmidt F, Setlur SR, et al. TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene 2007;26:4596-9.
    • (2007) Oncogene , vol.26 , pp. 4596-4599
    • Demichelis, F.1    Fall, K.2    Perner, S.3    Andren, O.4    Schmidt, F.5    Setlur, S.R.6
  • 14
    • 37049015104 scopus 로고    scopus 로고
    • Expression of the TMPRSS2: ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer
    • Nam RK, Sugar L, Yang W, Srivastava S, Klotz LH, Yang LY, et al. Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer. Br J Cancer 2007;97:1690-5.
    • (2007) Br J Cancer , vol.97 , pp. 1690-1695
    • Nam, R.K.1    Sugar, L.2    Yang, W.3    Srivastava, S.4    Klotz, L.H.5    Yang, L.Y.6
  • 15
    • 48249150750 scopus 로고    scopus 로고
    • Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer
    • Attard G, Clark J, Ambroisine L, Mills IG, Fisher G, Flohr P, et al. Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer. Br J Cancer 2008;99:314-20.
    • (2008) Br J Cancer , vol.99 , pp. 314-320
    • Attard, G.1    Clark, J.2    Ambroisine, L.3    Mills, I.G.4    Fisher, G.5    Flohr, P.6
  • 16
    • 50549085619 scopus 로고    scopus 로고
    • Gene panel model predictive of outcome in men at highrisk of systemic progression and death from prostate cancer after radical retropubic prostatectomy
    • Cheville JC, Karnes RJ, Therneau TM, Kosari F, Munz JM, Tillmans L, et al. Gene panel model predictive of outcome in men at highrisk of systemic progression and death from prostate cancer after radical retropubic prostatectomy. J Clin Oncol 2008;26:3930-6.
    • (2008) J Clin Oncol , vol.26 , pp. 3930-3936
    • Cheville, J.C.1    Karnes, R.J.2    Therneau, T.M.3    Kosari, F.4    Munz, J.M.5    Tillmans, L.6
  • 17
    • 60549107254 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    • Gopalan A, Leversha MA, Satagopan JM, Zhou Q, Al-Ahmadie HA, Fine SW, et al. TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res 2009;69:1400-6.
    • (2009) Cancer Res , vol.69 , pp. 1400-1406
    • Gopalan, A.1    Leversha, M.A.2    Satagopan, J.M.3    Zhou, Q.4    Al-Ahmadie, H.A.5    Fine, S.W.6
  • 18
    • 84862776695 scopus 로고    scopus 로고
    • ERG protein expression reflects hormonal treatment response and is associated with Gleason score and prostate cancer specific mortality
    • Bismar TA, Dolph M, Teng LH, Liu S, Donnelly B. ERG protein expression reflects hormonal treatment response and is associated with Gleason score and prostate cancer specific mortality. Eur J Cancer 2012;48:538-46.
    • (2012) Eur J Cancer , vol.48 , pp. 538-546
    • Bismar, T.A.1    Dolph, M.2    Teng, L.H.3    Liu, S.4    Donnelly, B.5
  • 19
    • 80052841071 scopus 로고    scopus 로고
    • ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy
    • Minner S, Enodien M, Sirma H, Luebke AM, Krohn A, Mayer PS, et al. ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res 2011;17:5878-88.
    • (2011) Clin Cancer Res , vol.17 , pp. 5878-5888
    • Minner, S.1    Enodien, M.2    Sirma, H.3    Luebke, A.M.4    Krohn, A.5    Mayer, P.S.6
  • 20
  • 22
    • 77955069195 scopus 로고    scopus 로고
    • Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
    • Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, et al. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat Genet 2010;42:668-75.
    • (2010) Nat Genet , vol.42 , pp. 668-675
    • Haffner, M.C.1    Aryee, M.J.2    Toubaji, A.3    Esopi, D.M.4    Albadine, R.5    Gurel, B.6
  • 23
    • 80052080913 scopus 로고    scopus 로고
    • TMPRSS2/ERG fusion gene expression alters chemoand radio-responsiveness in cell culture models of androgen independent prostate cancer
    • Mar. 10. Epub ahead of print
    • Swanson TA, Krueger SA, Galoforo S, Thibodeau BJ, Martinez AA, Wilson GD, et al. TMPRSS2/ERG fusion gene expression alters chemoand radio-responsiveness in cell culture models of androgen independent prostate cancer. Prostate. 2011 Mar. 10. [Epub ahead of print].
    • (2011) Prostate
    • Swanson, T.A.1    Krueger, S.A.2    Galoforo, S.3    Thibodeau, B.J.4    Martinez, A.A.5    Wilson, G.D.6
  • 24
    • 79955968629 scopus 로고    scopus 로고
    • Mechanistic rationale for inhibition of poly (ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer
    • Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, et al. Mechanistic rationale for inhibition of poly (ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell 2011;19:664-78.
    • (2011) Cancer Cell , vol.19 , pp. 664-678
    • Brenner, J.C.1    Ateeq, B.2    Li, Y.3    Yocum, A.K.4    Cao, Q.5    Asangani, I.A.6
  • 26
    • 84855454847 scopus 로고    scopus 로고
    • NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy
    • Locke JA, Zafarana G, Ishkanian AS, Milosevic M, Thoms J, Have CL, et al. NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy. Clin Cancer Res 2012;18:308-16.
    • (2012) Clin Cancer Res , vol.18 , pp. 308-316
    • Locke, J.A.1    Zafarana, G.2    Ishkanian, A.S.3    Milosevic, M.4    Thoms, J.5    Have, C.L.6
  • 28
    • 0020215010 scopus 로고
    • Dose fractionation, dose rate and iso-effect relationships for normal tissue responses
    • Barendsen GW. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses. Int J Radiat Oncol Biol Phys 1982;8:1981-97.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 1981-1997
    • Barendsen, G.W.1
  • 29
    • 85081797455 scopus 로고    scopus 로고
    • Short term hormone therapy and dose escalated radiation for localized prostate cancer: A randomized phase III study
    • Mok G, Glicksman R, Sykes J, Bayley A, Chung P, Bristow R, et al. Short term hormone therapy and dose escalated radiation for localized prostate cancer: a randomized phase III study. Radiol Oncol 2012;105:273-382.
    • (2012) Radiol Oncol , vol.105 , pp. 273-382
    • Mok, G.1    Glicksman, R.2    Sykes, J.3    Bayley, A.4    Chung, P.5    Bristow, R.6
  • 30
    • 77956584765 scopus 로고    scopus 로고
    • Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer
    • Ishkanian AS, Zafarana G, Thoms J, Bristow RG. Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer. Acta Oncol 2010;49:888-94.
    • (2010) Acta Oncol , vol.49 , pp. 888-894
    • Ishkanian, A.S.1    Zafarana, G.2    Thoms, J.3    Bristow, R.G.4
  • 32
    • 3343019470 scopus 로고
    • Measuring Nominal Scale Agreement among many raters
    • Fleiss J. Measuring Nominal Scale Agreement among many raters. Psychol Bull 1971;76:378-82.
    • (1971) Psychol Bull , vol.76 , pp. 378-382
    • Fleiss, J.1
  • 33
    • 84973587732 scopus 로고
    • A coefficient of agreement for nominal scales
    • Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas 1960;20:37-46.
    • (1960) Educ Psychol Meas , vol.20 , pp. 37-46
    • Cohen, J.1
  • 34
    • 33745184874 scopus 로고    scopus 로고
    • Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: Recommendations of the RTOG-ASTRO Phoenix Consensus Conference
    • Roach M III, Hanks G, Thames H Jr, Schellhammer P, Shipley WU, Sokol GH, et al. Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference. Int J Radiat Oncol Biol Phys 2006;65:965-74.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , pp. 965-974
    • Roach III, M.1    Hanks, G.2    Thames Jr., H.3    Schellhammer, P.4    Shipley, W.U.5    Sokol, G.H.6
  • 35
    • 66149098947 scopus 로고    scopus 로고
    • Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer
    • Attard G, Swennenhuis JF, Olmos D, Reid AH, Vickers E, A'Hern R, et al. Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Res 2009;69:2912-8.
    • (2009) Cancer Res , vol.69 , pp. 2912-2918
    • Attard, G.1    Swennenhuis, J.F.2    Olmos, D.3    Reid, A.H.4    Vickers, E.5    A'Hern, R.6
  • 36
    • 78549250106 scopus 로고    scopus 로고
    • The ability of biomarkers to predict systemic progression in men with highrisk prostate cancer treated surgically is dependent on ERG status
    • Karnes RJ, Cheville JC, Ida CM, Sebo TJ, Nair AA, Tang H, et al. The ability of biomarkers to predict systemic progression in men with highrisk prostate cancer treated surgically is dependent on ERG status. Cancer Res 2010;70:8994-9002.
    • (2010) Cancer Res , vol.70 , pp. 8994-9002
    • Karnes, R.J.1    Cheville, J.C.2    Ida, C.M.3    Sebo, T.J.4    Nair, A.A.5    Tang, H.6
  • 38
    • 77956458848 scopus 로고    scopus 로고
    • DNA repair targeting and radiotherapy: A focus on the therapeutic ratio
    • Thoms J, Bristow RG. DNA repair targeting and radiotherapy: a focus on the therapeutic ratio. Semin Radiat Oncol 2010;20:217-22.
    • (2010) Semin Radiat Oncol , vol.20 , pp. 217-222
    • Thoms, J.1    Bristow, R.G.2
  • 39
    • 84864716473 scopus 로고    scopus 로고
    • Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy
    • Zafarana G, Ishkanian AS, Malloff CA, Locke JA, Sykes J, Thoms J, et al. Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy. Cancer 2012;118:4053-62.
    • (2012) Cancer , vol.118 , pp. 4053-4062
    • Zafarana, G.1    Ishkanian, A.S.2    Malloff, C.A.3    Locke, J.A.4    Sykes, J.5    Thoms, J.6
  • 40
    • 0038475956 scopus 로고    scopus 로고
    • Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system
    • Freedland SJ, Pantuck AJ, Paik SH, Zisman A, Graeber TG, Eisenberg D, et al. Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. Prostate 2003;55:299-307.
    • (2003) Prostate , vol.55 , pp. 299-307
    • Freedland, S.J.1    Pantuck, A.J.2    Paik, S.H.3    Zisman, A.4    Graeber, T.G.5    Eisenberg, D.6
  • 43
    • 33745808783 scopus 로고    scopus 로고
    • Three-color FISH analysis of TMPRSS2/ERGfusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement
    • Yoshimoto M, Joshua AM, Chilton-Macneill S, Bayani J, Selvarajah S, Evans AJ, et al. Three-color FISH analysis of TMPRSS2/ERGfusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement. Neoplasia 2006;8:465-9.
    • (2006) Neoplasia , vol.8 , pp. 465-469
    • Yoshimoto, M.1    Joshua, A.M.2    Chilton-Macneill, S.3    Bayani, J.4    Selvarajah, S.5    Evans, A.J.6
  • 46
    • 68949094223 scopus 로고    scopus 로고
    • Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
    • Attard G, Reid AH, A'Hern R, Parker C, Oommen NB, Folkerd E, et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 2009;27:3742-8.
    • (2009) J Clin Oncol , vol.27 , pp. 3742-3748
    • Attard, G.1    Reid, A.H.2    A'Hern, R.3    Parker, C.4    Oommen, N.B.5    Folkerd, E.6
  • 47
    • 84875333536 scopus 로고    scopus 로고
    • ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients
    • Baena E, Shao Z, Linn DE, Glass K, Hamblen MJ, Fujiwara Y, et al. ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes Dev 2013;27:683-98.
    • (2013) Genes Dev , vol.27 , pp. 683-698
    • Baena, E.1    Shao, Z.2    Linn, D.E.3    Glass, K.4    Hamblen, M.J.5    Fujiwara, Y.6


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