-
1
-
-
27644466759
-
Autophagy and signaling: Their role in cell survival and cell death
-
Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Diff 2005;12:1509-18.
-
(2005)
Cell Death Diff
, vol.12
, pp. 1509-1518
-
-
Codogno, P.1
Meijer, A.J.2
-
2
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G, Jaattela M. Lysosomes and autophagy in cell death control. Nature Rev 2005;5:886-97.
-
(2005)
Nature Rev
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
3
-
-
33645088190
-
The role of apoptotic or nonapoptotic cell death in determining cellular response to anticancer treatment
-
Kim R, Emi M, Tanabe K, Uchida Y, Arihiro K. The role of apoptotic or nonapoptotic cell death in determining cellular response to anticancer treatment. Eur J Surg Oncol 2006;32:269-77.
-
(2006)
Eur J Surg Oncol
, vol.32
, pp. 269-277
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
Uchida, Y.4
Arihiro, K.5
-
4
-
-
33750284176
-
Autophagy in cancer: Good, bad, or both?
-
Hippert MM, O'Toole PS, Thorburn A. Autophagy in cancer: good, bad, or both? Cancer Res 2006;66:9349-51.
-
(2006)
Cancer Res
, vol.66
, pp. 9349-9351
-
-
Hippert, M.M.1
O'Toole, P.S.2
Thorburn, A.3
-
5
-
-
0029741890
-
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
-
Bursch W, Ellinger A, Kienzl H, et al. Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 1996;17:1595-607.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1595-1607
-
-
Bursch, W.1
Ellinger, A.2
Kienzl, H.3
-
6
-
-
0035863399
-
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
-
Paglin S, Hollister T, Delohery T, et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 2001;61:439-44.
-
(2001)
Cancer Res
, vol.61
, pp. 439-444
-
-
Paglin, S.1
Hollister, T.2
Delohery, T.3
-
7
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nature Rev Cancer 2005;5:726-34.
-
(2005)
Nature Rev Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
8
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
Amaravadi RK, Yu D, Lum JJ, et al. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 2007;117:326-36.
-
(2007)
J Clin Invest
, vol.117
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
-
9
-
-
0037451783
-
Autophagy: A barrier or an adaptive response to cancer
-
Ogier-Denis E, Codogno P. Autophagy: a barrier or an adaptive response to cancer. Biochim Biophys Acta 2003;1603:113-28.
-
(2003)
Biochim Biophys Acta
, vol.1603
, pp. 113-128
-
-
Ogier-Denis, E.1
Codogno, P.2
-
10
-
-
0037423403
-
Human Autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy
-
Marino G, Uria JA, Puente XS, Quesada V, Bordallo J, Lopez-Otin C. Human Autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy. J Biol Chem 2003;278:3671-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 3671-3678
-
-
Marino, G.1
Uria, J.A.2
Puente, X.S.3
Quesada, V.4
Bordallo, J.5
Lopez-Otin, C.6
-
12
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004;23:2891-906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
13
-
-
27644484061
-
Autophagy: Molecular machinery for self-eating
-
Yorimitsu T, Klionsky DJ. Autophagy: molecular machinery for self-eating. Cell Death Differ 2005;12 Suppl 2:1542-52.
-
(2005)
Cell Death Differ
, vol.12
, Issue.SUPPL. 2
, pp. 1542-1552
-
-
Yorimitsu, T.1
Klionsky, D.J.2
-
14
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999;402:672-6.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
-
15
-
-
0035870257
-
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
-
Liang XH, Yu J, Brown K, Levine B. Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res 2001;61:3443-9.
-
(2001)
Cancer Res
, vol.61
, pp. 3443-3449
-
-
Liang, X.H.1
Yu, J.2
Brown, K.3
Levine, B.4
-
16
-
-
0035032723
-
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
-
Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T. Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep 2001;2:330-5.
-
(2001)
EMBO Rep
, vol.2
, pp. 330-335
-
-
Kihara, A.1
Kabeya, Y.2
Ohsumi, Y.3
Yoshimori, T.4
-
17
-
-
0346998038
-
Defective autophagy leads to cancer
-
Edinger AL, Thompson CB. Defective autophagy leads to cancer. Cancer Cell 2003;4:422-4.
-
(2003)
Cancer Cell
, vol.4
, pp. 422-424
-
-
Edinger, A.L.1
Thompson, C.B.2
-
18
-
-
0030608395
-
Structural and functional analysis of APG5, a gene involved in autophagy in yeast
-
Kametaka S, Matsuura A, Wada Y, Ohsumi Y. Structural and functional analysis of APG5, a gene involved in autophagy in yeast. Gene 1996;178:139-43.
-
(1996)
Gene
, vol.178
, pp. 139-143
-
-
Kametaka, S.1
Matsuura, A.2
Wada, Y.3
Ohsumi, Y.4
-
19
-
-
0034099224
-
Apg5p functions in the sequestration step in the cytoplasm-to vacuole targeting and macroautophagy pathways
-
George MD, Baba M, Scott SV, et al. Apg5p functions in the sequestration step in the cytoplasm-to vacuole targeting and macroautophagy pathways. Mol Biol Cell 2000;11:969-82.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 969-982
-
-
George, M.D.1
Baba, M.2
Scott, S.V.3
-
20
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum JJ, Bauer DE, Kong M, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005;120:237-48.
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
-
21
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya P, Gonzalez-Polo RA, Casares N, et al. Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol 2005;25:1025-40.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Casares, N.3
-
22
-
-
23844483152
-
The apoptosis/autophagy paradox: Autophagic vacuolization before apoptotic death
-
Gonzalez-Polo RA, Boya P, Pauleau AL, et al. The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. J Cell Science 2005;118:3091-102.
-
(2005)
J Cell Science
, vol.118
, pp. 3091-3102
-
-
Gonzalez-Polo, R.A.1
Boya, P.2
Pauleau, A.L.3
-
23
-
-
2642553881
-
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
-
Yu L, Alva A, Su H, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004;304:1500-2.
-
(2004)
Science
, vol.304
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
-
24
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 2003;112:1809-20.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
-
25
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003;100:15077-82.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
26
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005;122:927-39.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
27
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
28
-
-
0037220165
-
The UMD-p53 database: New mutations and analysis tools
-
Beroud C, Soussi T. The UMD-p53 database: new mutations and analysis tools. Human mutation 2003;21:176-81.
-
(2003)
Human mutation
, vol.21
, pp. 176-181
-
-
Beroud, C.1
Soussi, T.2
-
29
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
Crighton D, Wilkinson S, O'Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006;126:121-34.
-
(2006)
Cell
, vol.126
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
-
30
-
-
27144503701
-
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death
-
Hoyer-Hansen M, Bastholm L, Mathiasen IS, Elling F, Jaattela M. Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death. Cell Death Differ 2005;12:1297-309.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1297-1309
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Mathiasen, I.S.3
Elling, F.4
Jaattela, M.5
-
31
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004;6:1221-8.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
-
32
-
-
0036006674
-
Ukrain, an alkaloid thiophosphoric acid derivative of Chelidonium majus L. protects human fibroblasts but not human tumour cells in vitro against ionizing radiation
-
Cordes N, Plasswilm L, Bamberg M, Rodemann HP. Ukrain, an alkaloid thiophosphoric acid derivative of Chelidonium majus L. protects human fibroblasts but not human tumour cells in vitro against ionizing radiation. Int J Radiat Biol 2002;78:17-27.
-
(2002)
Int J Radiat Biol
, vol.78
, pp. 17-27
-
-
Cordes, N.1
Plasswilm, L.2
Bamberg, M.3
Rodemann, H.P.4
-
33
-
-
0031756893
-
The presence of wild-type TP53 is necessary for the radioprotective effect of the Bowman-Birk proteinase inhibitor in normal fibroblasts
-
Dittmann KH, Gueven N, Mayer C, et al. The presence of wild-type TP53 is necessary for the radioprotective effect of the Bowman-Birk proteinase inhibitor in normal fibroblasts. Radiat Res 1998;150:648-55.
-
(1998)
Radiat Res
, vol.150
, pp. 648-655
-
-
Dittmann, K.H.1
Gueven, N.2
Mayer, C.3
-
34
-
-
0344553306
-
Bowman-Birk protease inhibitor activates DNA-dependent protein kinase and reduces formation of radiation-induced dicentric chromosomes
-
Dittmann K, Virsik-Kopp P, Mayer C, Rave-Frank M, Rodemann HP. Bowman-Birk protease inhibitor activates DNA-dependent protein kinase and reduces formation of radiation-induced dicentric chromosomes. Int J Radiat Biol 2003;79:801-8.
-
(2003)
Int J Radiat Biol
, vol.79
, pp. 801-808
-
-
Dittmann, K.1
Virsik-Kopp, P.2
Mayer, C.3
Rave-Frank, M.4
Rodemann, H.P.5
-
35
-
-
33749249893
-
Dexamethasone desensitizes hepatocellular and colorectal tumours toward cytotoxic therapy
-
Zhang C, Kolb A, Mattern J, et al. Dexamethasone desensitizes hepatocellular and colorectal tumours toward cytotoxic therapy. Cancer Lett 2006;242:104-11.
-
(2006)
Cancer Lett
, vol.242
, pp. 104-111
-
-
Zhang, C.1
Kolb, A.2
Mattern, J.3
-
36
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. Embo J 2000;19:5720-8.
-
(2000)
Embo J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
-
37
-
-
28244475972
-
Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells
-
Paglin S, Lee NY, Nakar C, et al. Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells. Cancer Res 2005;65:11061-70.
-
(2005)
Cancer Res
, vol.65
, pp. 11061-11070
-
-
Paglin, S.1
Lee, N.Y.2
Nakar, C.3
-
38
-
-
33745751085
-
Autophagic and tumour suppressor activity of a noval Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, et al. Autophagic and tumour suppressor activity of a noval Beclin1-binding protein UVRAG. Nat Cell Biol 2006;8:688-99.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
-
39
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
Brown JM, Wouters BG. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 1999;59:1391-9.
-
(1999)
Cancer Res
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
40
-
-
0037317521
-
The role of p53 in determining sensitivity to radiotherapy
-
Gudkov AV, Komarova EA. The role of p53 in determining sensitivity to radiotherapy. Nature Rev Cancer 2003;3:117-29.
-
(2003)
Nature Rev Cancer
, vol.3
, pp. 117-129
-
-
Gudkov, A.V.1
Komarova, E.A.2
-
41
-
-
20144373772
-
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy
-
Daido S, Yamamoto A, Fujiwara K, Sawaya R, Kondo S, Kondo Y. Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy. Cancer Res 2005;65:4368-75.
-
(2005)
Cancer Res
, vol.65
, pp. 4368-4375
-
-
Daido, S.1
Yamamoto, A.2
Fujiwara, K.3
Sawaya, R.4
Kondo, S.5
Kondo, Y.6
-
42
-
-
4344712684
-
Methods for monitoring autophagy
-
Mizushima N. Methods for monitoring autophagy. Int J Biochem Cell Biol 2004;36:2491-502.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2491-2502
-
-
Mizushima, N.1
-
43
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004;15:1101-11.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
44
-
-
35448980704
-
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
-
Sato K, Tsuchihara K, Fujii S, et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res 2007;67:9677-84.
-
(2007)
Cancer Res
, vol.67
, pp. 9677-9684
-
-
Sato, K.1
Tsuchihara, K.2
Fujii, S.3
-
45
-
-
0034877670
-
RNA interference: Listening to the sound of silence
-
Zamore PD. RNA interference: listening to the sound of silence. Nature Struct Biol 2001;8:746-50.
-
(2001)
Nature Struct Biol
, vol.8
, pp. 746-750
-
-
Zamore, P.D.1
-
47
-
-
0344873763
-
Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene
-
Crnkovic-Mertens I, Hoppe-Seyler F, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene 2003;22:8330-6.
-
(2003)
Oncogene
, vol.22
, pp. 8330-8336
-
-
Crnkovic-Mertens, I.1
Hoppe-Seyler, F.2
Butz, K.3
-
48
-
-
33646204392
-
Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size
-
Hosokawa N, Hara Y, Mizushima N. Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size. FEBS Letters 2006;580:2623-9.
-
(2006)
FEBS Letters
, vol.580
, pp. 2623-2629
-
-
Hosokawa, N.1
Hara, Y.2
Mizushima, N.3
-
49
-
-
0035911162
-
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
-
Mizushima N, Yamamoto A, Hatano M, et al. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. Journal Cell Biol 2001;152:657-68.
-
(2001)
Journal Cell Biol
, vol.152
, pp. 657-668
-
-
Mizushima, N.1
Yamamoto, A.2
Hatano, M.3
|