메뉴 건너뛰기




Volumn 5, Issue 11, 2005, Pages 867-875

Radiation and the microenvironment - Tumorigenesis and therapy

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; CLASTOGEN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MATRIX METALLOPROTEINASE; REACTIVE OXYGEN METABOLITE; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 28544438548     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrc1735     Document Type: Review
Times cited : (423)

References (95)
  • 1
    • 0034763554 scopus 로고    scopus 로고
    • Extracellular signaling via the microenvironment: A hypothesis relating carcinogenesis, bystander effects and genomic instability
    • Barcellos-Hoff, M. H. & Brooks, A. L. Extracellular signaling via the microenvironment: a hypothesis relating carcinogenesis, bystander effects and genomic instability. Radiat. Res. 156, 618-627 (2001).
    • (2001) Radiat. Res. , vol.156 , pp. 618-627
    • Barcellos-Hoff, M.H.1    Brooks, A.L.2
  • 2
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and the haemopoietic stem cell
    • Schofield, R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4, 7-25 (1978).
    • (1978) Blood Cells , vol.4 , pp. 7-25
    • Schofield, R.1
  • 3
    • 0033047022 scopus 로고    scopus 로고
    • Homing and mobilization in the stem cell niche
    • Whetton, A. D. & Graham, G. J. Homing and mobilization in the stem cell niche. Trends Cell Biol. 9, 233-238 (1999).
    • (1999) Trends Cell Biol. , vol.9 , pp. 233-238
    • Whetton, A.D.1    Graham, G.J.2
  • 5
    • 3843124144 scopus 로고    scopus 로고
    • A sense of danger from radiation
    • McBride, W. H. et al. A sense of danger from radiation. Radiat. Res. 162, 1-19 (2004).
    • (2004) Radiat. Res. , vol.162 , pp. 1-19
    • McBride, W.H.1
  • 6
    • 3643070885 scopus 로고
    • Modulation of the radiation response in vitro and in vivo by basic fibroblast growth factor
    • Fuks, Z. Modulation of the radiation response in vitro and in vivo by basic fibroblast growth factor. Proc. Am. Assoc. Cancer Res. 35, 709-710 (1994).
    • (1994) Proc. Am. Assoc. Cancer Res. , vol.35 , pp. 709-710
    • Fuks, Z.1
  • 7
    • 0025342073 scopus 로고
    • Transforming growth factor β1 expression in irradiated liver
    • Anscher, M. S., Crocker, I. R. & Jirtle, R. L. Transforming growth factor β1 expression in irradiated liver. Radiat. Res. 122, 77-85 (1990).
    • (1990) Radiat. Res. , vol.122 , pp. 77-85
    • Anscher, M.S.1    Crocker, I.R.2    Jirtle, R.L.3
  • 8
  • 9
    • 0031737426 scopus 로고    scopus 로고
    • Cellular sources of transforming growth factor-β isoforms in early and chronic radiation enteropathy
    • Wang, J., Zheng, H., Sung, C. C., Richter, K. K. & Hauer-Jensen, M. Cellular sources of transforming growth factor-β isoforms in early and chronic radiation enteropathy. Am. J. Pathol. 153, 1531-1540 (1998).
    • (1998) Am. J. Pathol. , vol.153 , pp. 1531-1540
    • Wang, J.1    Zheng, H.2    Sung, C.C.3    Richter, K.K.4    Hauer-Jensen, M.5
  • 10
    • 0022335318 scopus 로고
    • Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions
    • Lawrence, D. A., Pircher, R. & Jullien, P. Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions. Biochem. Biophys. Res. Comm. 133, 1026-1034 (1985).
    • (1985) Biochem. Biophys. Res. Comm. , vol.133 , pp. 1026-1034
    • Lawrence, D.A.1    Pircher, R.2    Jullien, P.3
  • 11
    • 0037439630 scopus 로고    scopus 로고
    • Making sense of latent TGFβ activation
    • Annes, J. P., Munger, J. S. & Rifkin, D. B. Making sense of latent TGFβ activation. J. Cell Sci. 116, 217-224 (2003).
    • (2003) J. Cell Sci. , vol.116 , pp. 217-224
    • Annes, J.P.1    Munger, J.S.2    Rifkin, D.B.3
  • 12
    • 0029736871 scopus 로고    scopus 로고
    • Redox-mediated activation of latent transforming growth factor-β1
    • Barcellos-Hoff, M. H. & Dix, T. A. Redox-mediated activation of latent transforming growth factor-β1. Mol. Endocrin. 10, 1077-1083 (1996).
    • (1996) Mol. Endocrin. , vol.10 , pp. 1077-1083
    • Barcellos-Hoff, M.H.1    Dix, T.A.2
  • 13
    • 0842288323 scopus 로고    scopus 로고
    • TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick, N. A. et al. TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303, 848-851 (2004).
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1
  • 14
    • 0037108674 scopus 로고    scopus 로고
    • Transforming growth factor-β1 mediates cellular response to DNA damage in situ
    • Ewan, K. B. et al. Transforming growth factor-β1 mediates cellular response to DNA damage in situ. Cancer Res. 62, 5627-5631 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 5627-5631
    • Ewan, K.B.1
  • 15
    • 0034080251 scopus 로고    scopus 로고
    • Gut instincts: Thoughts on intestinal epithelial stem cells
    • Booth, C. & Rotten, C. S. Gut instincts: thoughts on intestinal epithelial stem cells. J. Clin. Invest. 105, 1493-1499 (2000).
    • (2000) J. Clin. Invest. , vol.105 , pp. 1493-1499
    • Booth, C.1    Rotten, C.S.2
  • 16
    • 0024595303 scopus 로고
    • Differential expression of transforming growth factors α and β in rat intestinal epithelial cells
    • Koyama, S. Y. & Podolsky, D. K. Differential expression of transforming growth factors α and β in rat intestinal epithelial cells. J. Clin. Invest. 83, 1768-1773 (1989).
    • (1989) J. Clin. Invest. , vol.83 , pp. 1768-1773
    • Koyama, S.Y.1    Podolsky, D.K.2
  • 17
    • 0001360371 scopus 로고
    • Regulation of intestinal epithelial cell growth by transforming growth factor type β
    • Barnard, J. A., Beauchamp, R. D., Coffey, R. J. & Moses, H. L. Regulation of intestinal epithelial cell growth by transforming growth factor type β. Proc. Natl Acad. Sci. USA 86, 1578-1582 (1989).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1578-1582
    • Barnard, J.A.1    Beauchamp, R.D.2    Coffey, R.J.3    Moses, H.L.4
  • 18
    • 0030903741 scopus 로고    scopus 로고
    • Pretreatment with transforming growth factor β-3 protects small intestinal stem cells against radiation damage in vivo
    • Potten, C. S., Booth, D. & Haley, J. D. Pretreatment with transforming growth factor β-3 protects small intestinal stem cells against radiation damage in vivo. Br. J. Cancer 75, 1454-1459 (1997).
    • (1997) Br. J. Cancer , vol.75 , pp. 1454-1459
    • Potten, C.S.1    Booth, D.2    Haley, J.D.3
  • 19
    • 0030932012 scopus 로고    scopus 로고
    • Haemopoietic stem cells: Their heterogeneity and regulation
    • Graham, G. J. & Wright, E. G. Haemopoietic stem cells: their heterogeneity and regulation. Intl J. Exp. Pathol. 78, 197-218 (1997).
    • (1997) Intl. J. Exp. Pathol. , vol.78 , pp. 197-218
    • Graham, G.J.1    Wright, E.G.2
  • 20
    • 7944219768 scopus 로고    scopus 로고
    • Low-dose radiation (LDR) induces hematopoietic hormesis: LDR-induced mobilization of hematopoietic progenitor cells into peripheral blood circulation
    • Li, W., Wang, G., Cui, J., Xue, L. & Cai, L. Low-dose radiation (LDR) induces hematopoietic hormesis: LDR-induced mobilization of hematopoietic progenitor cells into peripheral blood circulation. Exp. Hematol. 32, 1088-1096 (2004).
    • (2004) Exp. Hematol. , vol.32 , pp. 1088-1096
    • Li, W.1    Wang, G.2    Cui, J.3    Xue, L.4    Cai, L.5
  • 21
    • 17144458848 scopus 로고    scopus 로고
    • Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival
    • Herodin, F., Bourin, P., Mayol, J. F., Lataillade, J. J. & Drouet, M. Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival. Blood 101, 2609-2616 (2003).
    • (2003) Blood , vol.101 , pp. 2609-2616
    • Herodin, F.1    Bourin, P.2    Mayol, J.F.3    Lataillade, J.J.4    Drouet, M.5
  • 22
    • 15244339041 scopus 로고    scopus 로고
    • Soluble factor(s) from bone marrow cells can rescue lethally irradiated mice by protecting endogenous hematopoietic stem cells
    • Zhao, Y., Zhan, Y., Burke, K. A. & Anderson, W. F. Soluble factor(s) from bone marrow cells can rescue lethally irradiated mice by protecting endogenous hematopoietic stem cells. Exp. Hematol. 33, 428-434 (2005).
    • (2005) Exp. Hematol. , vol.33 , pp. 428-434
    • Zhao, Y.1    Zhan, Y.2    Burke, K.A.3    Anderson, W.F.4
  • 23
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L. M. & Werb, Z. Inflammation and cancer. Nature 420, 860-867 (2002).
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 24
    • 0033848951 scopus 로고    scopus 로고
    • Transient infiltration of neutrophils into the thymus in association with apoptosis induced by whole-body X-irradiation
    • Uchimura, E., Watanabe, N., Niwa, O., Muto, M. & Kobayashi, Y. Transient infiltration of neutrophils into the thymus in association with apoptosis induced by whole-body X-irradiation. J. Leuk. Biol. 67, 780-784 (2000).
    • (2000) J. Leuk. Biol. , vol.67 , pp. 780-784
    • Uchimura, E.1    Watanabe, N.2    Niwa, O.3    Muto, M.4    Kobayashi, Y.5
  • 25
    • 0035950528 scopus 로고    scopus 로고
    • Inflammatory-type responses after exposure to ionizing radiation in vivo: A mechanism for radiation-induced bystander effects?
    • Lorimore, S. A., Coates, P. J., Scobie, G. E., Milne, G. & Wright, E. G. Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects? Oncogene 20, 7085-7095 (2001).
    • (2001) Oncogene , vol.20 , pp. 7085-7095
    • Lorimore, S.A.1    Coates, P.J.2    Scobie, G.E.3    Milne, G.4    Wright, E.G.5
  • 26
    • 0027297907 scopus 로고
    • Exacerbating factors of radiation-induced myeloid leukemogenesis
    • Yoshida, K., Nemoto, K., Nishimura, M. & Seki, M. Exacerbating factors of radiation-induced myeloid leukemogenesis. Leukemia Res. 17, 437-440 (1993).
    • (1993) Leukemia Res. , vol.17 , pp. 437-440
    • Yoshida, K.1    Nemoto, K.2    Nishimura, M.3    Seki, M.4
  • 27
    • 0014414665 scopus 로고
    • Influence of microbial environment on development of myeloid leukemia in X-irradiated RFM mice
    • Walburg, H. E., Congreve, G. U. & Upton, A. C. Influence of microbial environment on development of myeloid leukemia in X-irradiated RFM mice. Intl J. Cancer 3, 150-154 (1968).
    • (1968) Intl. J. Cancer , vol.3 , pp. 150-154
    • Walburg, H.E.1    Congreve, G.U.2    Upton, A.C.3
  • 29
    • 0037317216 scopus 로고    scopus 로고
    • Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors
    • Hayashi, T. et al. Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors. Intl J. Radiat. Biol. 79, 129-136 (2003). References 28 and 29 are epidemiological studies that report the long-term health effects, potentially mediated by low-level chronic inflammation, in individuals 50 years after IR exposure.
    • (2003) Intl. J. Radiat. Biol. , vol.79 , pp. 129-136
    • Hayashi, T.1
  • 30
    • 0028006359 scopus 로고
    • Reactive oxygen species, chromosome mutation, and cancer: Possible role of clastogenic factors in carcinogenesis
    • Emerit, I. Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis. Free Rad. Biol. Med. 16, 99-109 (1994).
    • (1994) Free Rad. Biol. Med. , vol.16 , pp. 99-109
    • Emerit, I.1
  • 31
    • 0026515714 scopus 로고
    • Transmission of chromosomal instability after plutonium α-particle irradiation
    • Kadhim, M. A. et al. Transmission of chromosomal instability after plutonium α-particle irradiation. Nature 355, 738-740 (1992).
    • (1992) Nature , vol.355 , pp. 738-740
    • Kadhim, M.A.1
  • 32
    • 0028169326 scopus 로고
    • α-particle-induced chromosomal instability in human bone marrow cells
    • Kadhim, M. A. et al. α-particle-induced chromosomal instability in human bone marrow cells. Lancet 344, 987-988 (1994).
    • (1994) Lancet , vol.344 , pp. 987-988
    • Kadhim, M.A.1
  • 33
    • 18144431719 scopus 로고    scopus 로고
    • Genotype-dependent induction of transmissible chromosomal instability by γ-radiation and the benzene metabolite hydroquinone
    • Gowans, I. D., Lorimore, S. A., McIlrath, J. M. & Wright, E. G. Genotype-dependent induction of transmissible chromosomal instability by γ-radiation and the benzene metabolite hydroquinone. Cancer Res. 65, 3527-3530 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 3527-3530
    • Gowans, I.D.1    Lorimore, S.A.2    McIlrath, J.M.3    Wright, E.G.4
  • 34
    • 0032510735 scopus 로고    scopus 로고
    • Chromosomal instability in the descendants of unirradiated surviving cells after α-particle irradiation
    • Lorimore, S. A. et al. Chromosomal instability in the descendants of unirradiated surviving cells after α-particle irradiation. Proc. Natl Acad. Sci. USA 95, 5730-5733 (1998). This study reports that IR with α-particles can elicit persistent genomic instability in non-irradiated cells.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5730-5733
    • Lorimore, S.A.1
  • 35
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. Alternative activation of macrophages. Nature Rev. Immunol. 3, 23-35 (2003).
    • (2003) Nature Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 36
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • Balkwill, F., Charles, K. A. & Mantovani, A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7, 211-217 (2005).
    • (2005) Cancer Cell , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 38
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani, A., Sozzani, S., Locati, M., Allavena, P. & Sica, A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23, 549-555 (2002).
    • (2002) Trends Immunol. , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 39
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani, A. et al. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25, 677-686 (2004).
    • (2004) Trends Immunol. , vol.25 , pp. 677-686
    • Mantovani, A.1
  • 40
    • 23944503319 scopus 로고    scopus 로고
    • Application of two-dimensional difference gel electrophoresis to studying bone marrow macrophages and their in vivo responses to ionizing radiation
    • Chen, C., Boylan, M. T., Evans, C. A., Whetton, A. D. & Wright, E. G. Application of two-dimensional difference gel electrophoresis to studying bone marrow macrophages and their in vivo responses to ionizing radiation. J. Proteome Res. 4, 1371-1380 (2005).
    • (2005) J. Proteome Res. , vol.4 , pp. 1371-1380
    • Chen, C.1    Boylan, M.T.2    Evans, C.A.3    Whetton, A.D.4    Wright, E.G.5
  • 41
    • 0035075404 scopus 로고    scopus 로고
    • In vivo chromosomal instability and transmissible aberrations in the progeny of haemopoietic stem cells induced by high- and low-LET radiations
    • Watson, G., E,, Pocock, D. A., Papworth, D., Lorimore, S. A. & Wright, E. G. In vivo chromosomal instability and transmissible aberrations in the progeny of haemopoietic stem cells induced by high- and low-LET radiations. Intl J. Radiat. Biol. 77, 409-417 (2001).
    • (2001) Intl. J. Radiat. Biol. , vol.77 , pp. 409-417
    • Watson, G.1    Pocock, D.A.2    Papworth, D.3    Lorimore, S.A.4    Wright, E.G.5
  • 42
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF
    • Fadok, V. A. et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF. J. Clin. Invest. 101, 890-898 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 890-898
    • Fadok, V.A.1
  • 43
    • 0036636745 scopus 로고    scopus 로고
    • The role of the macrophage in apoptosis: Hunter, gatherer, and regulator
    • Geske, F. J., Monks, J., Lehman, L. & Fadok, V. A. The role of the macrophage in apoptosis: hunter, gatherer, and regulator. Intl J. Hematol. 76, 16-26 (2002).
    • (2002) Intl. J. Hematol. , vol.76 , pp. 16-26
    • Geske, F.J.1    Monks, J.2    Lehman, L.3    Fadok, V.A.4
  • 44
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • Savill, J., Dransfield, I., Gregory, C. & Haslett, C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nature Rev. Immunol. 2, 965-975 (2002).
    • (2002) Nature Rev. Immunol. , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 46
    • 0033950998 scopus 로고    scopus 로고
    • CD14-dependent clearance of apoptotic cells: Relevance to the immune system
    • Gregory, C. D. CD14-dependent clearance of apoptotic cells: relevance to the immune system. Curr. Opin. Immunol. 12, 27-34 (2000).
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 27-34
    • Gregory, C.D.1
  • 47
    • 0032034449 scopus 로고    scopus 로고
    • The potential influence of radiation-induced microenvironments in neoplastic progression
    • Barcellos-Hoff, M. H. The potential influence of radiation-induced microenvironments in neoplastic progression. J. Mammary Gland Biol. Neoplasia 3, 165-175 (1998).
    • (1998) J. Mammary Gland Biol. Neoplasia , vol.3 , pp. 165-175
    • Barcellos-Hoff, M.H.1
  • 48
    • 0034161922 scopus 로고    scopus 로고
    • Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
    • Barcellos-Hoff, M. H. & Ravani, S. A. Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res. 60, 1254-1260 (2000). These experiments demonstrated that persistent IR-induced changes in the tissue microenvironment affect neoplastic progression of non-irradiated premalignant epithelial cells.
    • (2000) Cancer Res. , vol.60 , pp. 1254-1260
    • Barcellos-Hoff, M.H.1    Ravani, S.A.2
  • 49
    • 0037071538 scopus 로고    scopus 로고
    • Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site
    • Morgan, J. E. et al. Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site. J. Cell Biol. 157, 693-702 (2002).
    • (2002) J. Cell Biol. , vol.157 , pp. 693-702
    • Morgan, J.E.1
  • 50
    • 0141813439 scopus 로고    scopus 로고
    • Donor leukaemia: Perhaps a more common occurrence than we thought!
    • McCann, S. & Wright, E. Donor leukaemia: perhaps a more common occurrence than we thought! Bone Marrow Transplant. 32, 455-457 (2003).
    • (2003) Bone Marrow Transplant. , vol.32 , pp. 455-457
    • McCann, S.1    Wright, E.2
  • 51
    • 0029869612 scopus 로고    scopus 로고
    • Effects of irradiation of CBA/CA mice on hematopoietic stem cells and stromal cells in long-term bone marrow cultures
    • Greenberger, J. S. et al. Effects of irradiation of CBA/CA mice on hematopoietic stem cells and stromal cells in long-term bone marrow cultures. Leukemia 10, 514-527 (1996).
    • (1996) Leukemia , vol.10 , pp. 514-527
    • Greenberger, J.S.1
  • 52
    • 0027944180 scopus 로고
    • Involvement of the bone marrow stroma in the residual hematopoietic damage induced by irradiation of adult and young mice
    • Grande, T. & Bueren, J. A. Involvement of the bone marrow stroma in the residual hematopoietic damage induced by irradiation of adult and young mice. Exp. Hematol. 22, 1283-1287 (1994).
    • (1994) Exp. Hematol. , vol.22 , pp. 1283-1287
    • Grande, T.1    Bueren, J.A.2
  • 53
    • 0026537045 scopus 로고
    • Humoral and cell surface interactions during γ-irradiation leukemogenesis in vitro
    • Greenberger, J. et al. Humoral and cell surface interactions during γ-irradiation leukemogenesis in vitro. Exp. Hematol. 20, 92-102 (1992).
    • (1992) Exp. Hematol. , vol.20 , pp. 92-102
    • Greenberger, J.1
  • 54
    • 0023947579 scopus 로고
    • A model system for leukemic transformation of immortalized hemopoietic cells in irradiated recipient mice
    • Duhrsen, U. & Metcalf, D. A model system for leukemic transformation of immortalized hemopoietic cells in irradiated recipient mice. Leukemia 2, 329-333 (1988).
    • (1988) Leukemia , vol.2 , pp. 329-333
    • Duhrsen, U.1    Metcalf, D.2
  • 55
    • 0025141654 scopus 로고
    • Effects of irradiation of recipient mice on the behavior and leukemogenic potential of factor-dependent hematopoietic cell lines
    • Duhrsen, U. & Metcalf, D. Effects of irradiation of recipient mice on the behavior and leukemogenic potential of factor-dependent hematopoietic cell lines. Blood 75, 190-197 (1990).
    • (1990) Blood , vol.75 , pp. 190-197
    • Duhrsen, U.1    Metcalf, D.2
  • 56
    • 0033932014 scopus 로고    scopus 로고
    • Activation of the nitric oxide synthase 2 pathway in the response of bone marrow stromal cells to high doses of ionizing radiation
    • Gorbunov, N. V. et al. Activation of the nitric oxide synthase 2 pathway in the response of bone marrow stromal cells to high doses of ionizing radiation. Radiat. Res. 154, 73-86 (2000).
    • (2000) Radiat. Res. , vol.154 , pp. 73-86
    • Gorbunov, N.V.1
  • 57
    • 0042307513 scopus 로고    scopus 로고
    • The two faces of transforming growth factor β in carcinogenesis
    • Roberts, A. B. & Wakefield, L. M. The two faces of transforming growth factor β in carcinogenesis. Proc. Natl Acad. Sci. USA 100, 8621-8623 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8621-8623
    • Roberts, A.B.1    Wakefield, L.M.2
  • 58
    • 0028890174 scopus 로고
    • The origin of the myofibroblasts in breast: Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells
    • Ronnov-Jessen, L., Petersen, O. W., Kotelianski, V. & Bissell, M. J. The origin of the myofibroblasts in breast: recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells. J. Clin. Invest. 95, 859-873 (1995).
    • (1995) J. Clin. Invest. , vol.95 , pp. 859-873
    • Ronnov-Jessen, L.1    Petersen, O.W.2    Kotelianski, V.3    Bissell, M.J.4
  • 59
    • 7244250188 scopus 로고    scopus 로고
    • Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-β or wounding
    • De Wever, O. et al. Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-β or wounding. J. Cell Sci. 117, 4691-4703 (2004).
    • (2004) J. Cell Sci. , vol.117 , pp. 4691-4703
    • De Wever, O.1
  • 60
    • 0033789360 scopus 로고    scopus 로고
    • Spontaneous and radiation-induced differentiationof fibroblasts
    • Herskind, C. & Rodemann, H. P. Spontaneous and radiation-induced differentiationof fibroblasts. Exp. Gerontol. 35, 747-755 (2000).
    • (2000) Exp. Gerontol. , vol.35 , pp. 747-755
    • Herskind, C.1    Rodemann, H.P.2
  • 61
    • 0028287098 scopus 로고
    • N-Nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations
    • Cha, R. S., Thilly W. G. & Zarbl, H. N-Nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations. Proc. Natl Acad. Sci. USA 91, 3749-3753 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3749-3753
    • Cha, R.S.1    Thilly, W.G.2    Zarbl, H.3
  • 62
  • 63
    • 14044250003 scopus 로고    scopus 로고
    • Stroma is not a major target in 7, 12-dimethlybenzanthracene mediated tumorigenesis of mouse mammary preneoplasia
    • Medina, D. & Kittrell, F. S. Stroma is not a major target in 7, 12-dimethlybenzanthracene mediated tumorigenesis of mouse mammary preneoplasia. J. Cell Sci. 118, 123-127 (2005).
    • (2005) J. Cell Sci. , vol.118 , pp. 123-127
    • Medina, D.1    Kittrell, F.S.2
  • 64
    • 0022397711 scopus 로고
    • Wounding and its role in RSV-mediated tumor formation
    • Dolberg, D. S., Holingworth, R., Hertle, M. & Bissell, M. J. Wounding and its role in RSV-mediated tumor formation. Science 230, 676-678 (1985).
    • (1985) Science , vol.230 , pp. 676-678
    • Dolberg, D.S.1    Holingworth, R.2    Hertle, M.3    Bissell, M.J.4
  • 65
    • 0032477806 scopus 로고    scopus 로고
    • Tumorigenic conversion of immortal human keratinocytes through stromal cell activation
    • Skobe, M. & Fusenig, N. E. Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc. Natl Acad. Sci. USA 95, 1050-1055 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1050-1055
    • Skobe, M.1    Fusenig, N.E.2
  • 66
    • 0033597726 scopus 로고    scopus 로고
    • The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis
    • Sternlicht, M. D. et al. The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell 98, 137-146 (1999).
    • (1999) Cell , vol.98 , pp. 137-146
    • Sternlicht, M.D.1
  • 67
    • 0029312344 scopus 로고
    • Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1
    • Sympson, C. J., Bissell, M. J. & Werb, Z. Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1. Semin. Cancer Biol. 6, 159-163 (1995).
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 159-163
    • Sympson, C.J.1    Bissell, M.J.2    Werb, Z.3
  • 68
    • 0346788624 scopus 로고    scopus 로고
    • Radiation-induced histopathologic changes of the breast: The effects of time
    • Moore, G. H., Schiller, J. E. & Moore, G. K. Radiation-induced histopathologic changes of the breast: the effects of time. Am. J. Surg. Pathol. 28, 47-53 (2004).
    • (2004) Am. J. Surg. Pathol. , vol.28 , pp. 47-53
    • Moore, G.H.1    Schiller, J.E.2    Moore, G.K.3
  • 69
    • 0025060888 scopus 로고
    • Radiation and other pathological changes in breast tissue after conservation treatment for carcinoma
    • Girling, A. C., Hanby, A. M. & Millis, R. R. Radiation and other pathological changes in breast tissue after conservation treatment for carcinoma. J. Clin. Pathol. 43, 152-156 (1990).
    • (1990) J. Clin. Pathol. , vol.43 , pp. 152-156
    • Girling, A.C.1    Hanby, A.M.2    Millis, R.R.3
  • 71
    • 0021171522 scopus 로고
    • Cell-cell matrix interactions in induced lung injury I. the effects of X-irradiation on basal laminar proteoglycans
    • Penney, D. P. & Rosenkrans, W. A. Jr. Cell-cell matrix interactions in induced lung injury I. The effects of X-irradiation on basal laminar proteoglycans. Radiat. Res. 99, 410-419 (1984).
    • (1984) Radiat. Res. , vol.99 , pp. 410-419
    • Penney, D.P.1    Rosenkrans Jr., W.A.2
  • 72
    • 0027293946 scopus 로고
    • Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in murine mammary gland
    • Barcellos-Hoff, M. H. Radiation-induced transforming growth factor β and subsequent extracellular matrix reorganization in murine mammary gland. Cancer Res. 53, 3880-3886 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 3880-3886
    • Barcellos-Hoff, M.H.1
  • 73
    • 0025969206 scopus 로고
    • Long-term overproduction of collagen in radiation-induced fibrosis
    • Remy, J., Wegrowski, J., Crechet, F., Marin, M. & Daburon, F. Long-term overproduction of collagen in radiation-induced fibrosis. Radiat. Res. 125, 14-19 (1991).
    • (1991) Radiat. Res. , vol.125 , pp. 14-19
    • Remy, J.1    Wegrowski, J.2    Crechet, F.3    Marin, M.4    Daburon, F.5
  • 74
    • 0024242304 scopus 로고
    • The effects of irradiation on breast cancer and the breast
    • Friedman, N. The effects of irradiation on breast cancer and the breast. CA Cancer J. Clin. 38, 368-371 (1988).
    • (1988) CA Cancer J. Clin. , vol.38 , pp. 368-371
    • Friedman, N.1
  • 75
    • 0025605879 scopus 로고
    • Tumor radiocurability: Relationship to intrinsic tumor heterogeneity and to the tumor bed effect
    • Leith, J. T. & Michelson, S. Tumor radiocurability: relationship to intrinsic tumor heterogeneity and to the tumor bed effect. Invasion Metastasis 10, 329-351 (1990).
    • (1990) Invasion Metastasis , vol.10 , pp. 329-351
    • Leith, J.T.1    Michelson, S.2
  • 76
    • 0021809735 scopus 로고
    • Reduced thoracic vertebrae metastases following post mastectomy parasternal irradiation
    • Hercbergs, A., Werner, A. & Brenner, H. J. Reduced thoracic vertebrae metastases following post mastectomy parasternal irradiation. Intl J. Radiat. Oncol. Biol. Phys. 11, 773-776 (1985).
    • (1985) Intl. J. Radiat. Oncol. Biol. Phys. , vol.11 , pp. 773-776
    • Hercbergs, A.1    Werner, A.2    Brenner, H.J.3
  • 77
    • 0027071855 scopus 로고
    • Radiation treatment of prostate bone metastases and the biological considerations
    • Bagshaw, M. A., Kaplan, I. D., Valdagni, R. & Cox, R. S. Radiation treatment of prostate bone metastases and the biological considerations. Adv. Exp. Med. Biol. 324, 255-268 (1992).
    • (1992) Adv. Exp. Med. Biol. , vol.324 , pp. 255-268
    • Bagshaw, M.A.1    Kaplan, I.D.2    Valdagni, R.3    Cox, R.S.4
  • 78
    • 0038626211 scopus 로고    scopus 로고
    • Tumor response to radiotherapy regulated by endothelial cell apoptosis
    • Garcia-Barros, M. et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300, 1155-1159 (2003).
    • (2003) Science , vol.300 , pp. 1155-1159
    • Garcia-Barros, M.1
  • 79
    • 0035854479 scopus 로고    scopus 로고
    • Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
    • Paris, F. et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293, 293-297 (2001). This study described a novel mechanism of tissue damage through the loss of endothelial cells from IR-induced signalling through the ceramide pathway.
    • (2001) Science , vol.293 , pp. 293-297
    • Paris, F.1
  • 80
    • 10744233540 scopus 로고    scopus 로고
    • Interference with transforming growth factor-β/Smad3 signaling results in accelerated healing of wounds in previously irradiated skin
    • Flanders, K. C. et al. Interference with transforming growth factor-β/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin. Am. J. Pathol. 163, 2247-2257 (2003).
    • (2003) Am. J. Pathol. , vol.163 , pp. 2247-2257
    • Flanders, K.C.1
  • 81
    • 0041419545 scopus 로고    scopus 로고
    • Soluble TGFβ type II receptor gene therapy ameliorates acute radiation-induced pulmonary injury in rats
    • Rabbani, Z. N. et al. Soluble TGFβ type II receptor gene therapy ameliorates acute radiation-induced pulmonary injury in rats. Intl J. Radiat. Oncol. Biol. Phys. 57, 563-572 (2003).
    • (2003) Intl. J. Radiat. Oncol. Biol. Phys. , vol.57 , pp. 563-572
    • Rabbani, Z.N.1
  • 82
    • 2442481893 scopus 로고    scopus 로고
    • Amelioration of radiation-induced fibrosis: Inhibition of transforming growth factor-β signaling by Halofuginone
    • Xavier, S. et al. Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-β signaling by Halofuginone. J. Biol. Chem. 279, 15167-15176 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 15167-15176
    • Xavier, S.1
  • 83
    • 0028923805 scopus 로고
    • Normal tissue injury after cancer therapy is a local response exacerbated by an endocrine effect of TGFβ
    • Anscher, M. S., Kong, F., Murase, T. & Jirtle, R. L. Normal tissue injury after cancer therapy is a local response exacerbated by an endocrine effect of TGFβ. Br. J. Radiat. 68, 331-333 (1995).
    • (1995) Br. J. Radiat. , vol.68 , pp. 331-333
    • Anscher, M.S.1    Kong, F.2    Murase, T.3    Jirtle, R.L.4
  • 84
    • 0031773119 scopus 로고    scopus 로고
    • How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues
    • Barcellos-Hoff, M. H. How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues. Radiat. Res. 150, S109-S120 (1998).
    • (1998) Radiat. Res. , vol.150
    • Barcellos-Hoff, M.H.1
  • 85
    • 28544439675 scopus 로고    scopus 로고
    • A systems biology approach to multicellular and multi-generational radiation responses
    • In the press
    • Barcellos-Hoff, M. H. & Costes, S. V. A systems biology approach to multicellular and multi-generational radiation responses. Mutat. Res. (In the press).
    • Mutat. Res.
    • Barcellos-Hoff, M.H.1    Costes, S.V.2
  • 86
    • 0029997709 scopus 로고    scopus 로고
    • Role of bone marrow stromal cells in irradiation leukemogenesis
    • Greenberger, J. S. et al. Role of bone marrow stromal cells in irradiation leukemogenesis. Acta Haematologica 96, 1-15 (1996).
    • (1996) Acta Haematologica , vol.96 , pp. 1-15
    • Greenberger, J.S.1
  • 87
    • 0031956913 scopus 로고    scopus 로고
    • Hierarchcal and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents
    • Trosko, J. E. Hierarchcal and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents. Environ. Health Perspect. 106, 331-339 (1998).
    • (1998) Environ. Health Perspect. , vol.106 , pp. 331-339
    • Trosko, J.E.1
  • 88
    • 7644232963 scopus 로고    scopus 로고
    • Damaging and protective cell signalling in the untargeted effects of ionizing radiation
    • Coates, P. J., Lorimore, S. A. & Wright, E. G. Damaging and protective cell signalling in the untargeted effects of ionizing radiation. Mutat. Res. 568, 5-20 (2004).
    • (2004) Mutat. Res. , vol.568 , pp. 5-20
    • Coates, P.J.1    Lorimore, S.A.2    Wright, E.G.3
  • 89
    • 0027082811 scopus 로고
    • The extracellular regulation of growth factor action
    • Flaumenhaft, R. & Rifkin, D. B. The extracellular regulation of growth factor action. Mol. Biol. Cell 3, 1057-1065 (1992).
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1057-1065
    • Flaumenhaft, R.1    Rifkin, D.B.2
  • 90
    • 0024994691 scopus 로고
    • Physiochemical activation of recombinant latent transforming growth factor-β's 1, 2, and 3
    • Brown, P. D., Wakefield, L. M., Levinson, A. D. & Sporn, M. B. Physiochemical activation of recombinant latent transforming growth factor-β's 1, 2, and 3. Growth Factors 3, 35-43 (1990).
    • (1990) Growth Factors , vol.3 , pp. 35-43
    • Brown, P.D.1    Wakefield, L.M.2    Levinson, A.D.3    Sporn, M.B.4
  • 91
    • 84965810273 scopus 로고
    • Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
    • DeOme, K. B., Faulkin, L. J. J., Bern, H. A. & Blair, P. B. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res. 19, 515-520 (1959).
    • (1959) Cancer Res. , vol.19 , pp. 515-520
    • DeOme, K.B.1    Faulkin, L.J.J.2    Bern, H.A.3    Blair, P.B.4
  • 92
    • 0021153316 scopus 로고
    • Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro
    • Danielson, K. G., Oborn, C. J., Durban, E. M., Buetel, J. S. & Medina, D. Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro. Proc. Natl Acad. Sci. USA 81, 3756-3760 (1984).
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 3756-3760
    • Danielson, K.G.1    Oborn, C.J.2    Durban, E.M.3    Buetel, J.S.4    Medina, D.5
  • 93
    • 0020329374 scopus 로고
    • Effects of feeder layers made of human, mouse, hamster, and rat cells on the cloning efficiency of transformed human cells
    • Namba, M., Fukushima, F. & Kimoto, T. Effects of feeder layers made of human, mouse, hamster, and rat cells on the cloning efficiency of transformed human cells. In Vitro Cell Dev. Biol. 18, 469-475 (1982).
    • (1982) In Vitro Cell Dev. Biol. , vol.18 , pp. 469-475
    • Namba, M.1    Fukushima, F.2    Kimoto, T.3
  • 94
    • 23044435948 scopus 로고    scopus 로고
    • Cellular mechanisms for low-dose ionizing radiation-induced perturbation of the breast tissue microenvironment
    • Tsai, K. K, Chang, E. Y., Little, S. B & Yuan, S. M. Cellular mechanisms for low-dose ionizing radiation-induced perturbation of the breast tissue microenvironment. Cancer Res. 65, 6734-6744 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 6734-6744
    • Tsai, K.K.1    Chang, E.Y.2    Little, S.B.3    Yuan, S.M.4
  • 95
    • 11844293451 scopus 로고    scopus 로고
    • Radiotherapy: What can be achieved by technical improvements in dose delivery?
    • Moran, E. S., Elshaikh, M. A. & Lawrence, T. S. Radiotherapy: what can be achieved by technical improvements in dose delivery? Lancet Oncol. 6, 51-58 (2005).
    • (2005) Lancet Oncol. , vol.6 , pp. 51-58
    • Moran, E.S.1    Elshaikh, M.A.2    Lawrence, T.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.