메뉴 건너뛰기




Volumn 3, Issue 1, 2013, Pages 360-395

Non-coding RNAs as potential neuroprotectants against ischemic brain injury

Author keywords

Brain; Ischemia; LncRNA; miRNA; Neuroprotectant; Non coding RNAs; piRNA

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; ACTIVATING TRANSCRIPTION FACTOR 4; ANTICOAGULANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIN D1; HOX PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; JAGGED1; MICRORNA 124; MICRORNA 223; MICRORNA 9; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PIWI INTERACTING RNA; PROTEIN BCL 2; RNA POLYMERASE II; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84886283181     PISSN: None     EISSN: 20763425     Source Type: Journal    
DOI: 10.3390/brainsci3010360     Document Type: Review
Times cited : (39)

References (242)
  • 3
    • 34248162440 scopus 로고    scopus 로고
    • Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs
    • Ponjavic, J.; Ponting, C.P.; Lunter, G. Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs. Genome Res. 2007, 17, 556-565.
    • (2007) Genome Res , vol.17 , pp. 556-565
    • Ponjavic, J.1    Ponting, C.P.2    Lunter, G.3
  • 4
    • 78650112000 scopus 로고    scopus 로고
    • The emerging role of epigenetics in stroke: II. RNA regulatory circuitry
    • Qureshi, I.A.; Mehler, M.F. The emerging role of epigenetics in stroke: II. RNA regulatory circuitry. Arch. Neurol. 2010, 67, 1435-1441.
    • (2010) Arch. Neurol , vol.67 , pp. 1435-1441
    • Qureshi, I.A.1    Mehler, M.F.2
  • 5
    • 60149099385 scopus 로고    scopus 로고
    • Evolution and functions of long noncoding RNAs
    • Ponting, C.P.; Oliver, P.L.; Reik, W. Evolution and functions of long noncoding RNAs. Cell 2009, 136, 629-641.
    • (2009) Cell , vol.136 , pp. 629-641
    • Ponting, C.P.1    Oliver, P.L.2    Reik, W.3
  • 7
    • 84856492490 scopus 로고    scopus 로고
    • Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
    • Ng, S.Y.; Johnson, R.; Stanton, L.W. Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors. EMBO J. 2012, 31, 522-533.
    • (2012) EMBO J , vol.31 , pp. 522-533
    • Ng, S.Y.1    Johnson, R.2    Stanton, L.W.3
  • 9
    • 63649138643 scopus 로고    scopus 로고
    • MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
    • Cheng, L.C.; Pastrana, E.; Tavazoie, M.; Doetsch, F. MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 2009, 12, 399-408.
    • (2009) Nat. Neurosci , vol.12 , pp. 399-408
    • Cheng, L.C.1    Pastrana, E.2    Tavazoie, M.3    Doetsch, F.4
  • 12
    • 85027951676 scopus 로고    scopus 로고
    • Functions of noncoding RNAs in neural development and neurological diseases
    • Bian, S.; Sun, T. Functions of noncoding RNAs in neural development and neurological diseases. Mol. Neurobiol. 2011, 44, 359-373.
    • (2011) Mol. Neurobiol , vol.44 , pp. 359-373
    • Bian, S.1    Sun, T.2
  • 13
    • 41249102422 scopus 로고    scopus 로고
    • MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion
    • Jeyaseelan, K.; Lim, K.Y.; Armugam, A. MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion. Stroke 2008, 39, 959-966.
    • (2008) Stroke , vol.39 , pp. 959-966
    • Jeyaseelan, K.1    Lim, K.Y.2    Armugam, A.3
  • 14
    • 84866740972 scopus 로고    scopus 로고
    • Effect of focal ischemia on long noncoding RNAs
    • Dharap, A.; Nakka, V.P.; Vemuganti, R. Effect of focal ischemia on long noncoding RNAs. Stroke 2012, 43, 2800-2802.
    • (2012) Stroke , vol.43 , pp. 2800-2802
    • Dharap, A.1    Nakka, V.P.2    Vemuganti, R.3
  • 18
    • 0029834603 scopus 로고    scopus 로고
    • Immediate early gene expression in response to cerebral ischemia. Friend or foe
    • Akins, P.T.; Liu, P.K.; Hsu, C.Y. Immediate early gene expression in response to cerebral ischemia. Friend or foe? Stroke 1996, 27, 1682-1687.
    • (1996) Stroke , vol.27 , pp. 1682-1687
    • Akins, P.T.1    Liu, P.K.2    Hsu, C.Y.3
  • 19
    • 77953037882 scopus 로고    scopus 로고
    • Targeting ischemic penumbra: Part I-From pathophysiology to therapeutic strategy
    • Liu, S.; Levine, S.R.; Winn, H.R. Targeting ischemic penumbra: Part I-From pathophysiology to therapeutic strategy. J. Exp. Stroke Transl. Med. 2010, 3, 47-55.
    • (2010) J. Exp. Stroke Transl. Med , vol.3 , pp. 47-55
    • Liu, S.1    Levine, S.R.2    Winn, H.R.3
  • 21
    • 77549088509 scopus 로고    scopus 로고
    • MiR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia
    • Yin, K.J.; Deng, Z.; Huang, H.; Hamblin, M.; Xie, C.; Zhang, J.; Chen, Y.E. MiR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia. Neurobiol. Dis. 2010, 38, 17-26.
    • (2010) Neurobiol Dis , vol.38 , pp. 17-26
    • Yin, K.J.1    Deng, Z.2    Huang, H.3    Hamblin, M.4    Xie, C.5    Zhang, J.6    Chen, Y.E.7
  • 22
    • 77956541446 scopus 로고    scopus 로고
    • MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia
    • Sepramaniam, S.; Armugam, A.; Lim, K.Y.; Karolina, D.S.; Swaminathan, P.; Tan, J.R.; Jeyaseelan, K. MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia. J. Biol. Chem. 2010, 285, 29223-29230.
    • (2010) J. Biol. Chem , vol.285 , pp. 29223-29230
    • Sepramaniam, S.1    Armugam, A.2    Lim, K.Y.3    Karolina, D.S.4    Swaminathan, P.5    Tan, J.R.6    Jeyaseelan, K.7
  • 23
    • 65549098614 scopus 로고    scopus 로고
    • Apoptotic mechanisms after cerebral ischemia
    • Broughton, B.R.; Reutens, D.C.; Sobey, C.G. Apoptotic mechanisms after cerebral ischemia. Stroke 2009, 40, e331-e339.
    • (2009) Stroke , vol.40
    • Broughton, B.R.1    Reutens, D.C.2    Sobey, C.G.3
  • 25
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs, Genomics, biogenesis, mechanism, and function
    • Bartel, D.P. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 27
    • 60149098474 scopus 로고    scopus 로고
    • Small RNAs as guardians of the genome
    • Malone, C.D.; Hannon, G.J. Small RNAs as guardians of the genome. Cell 2009, 136, 656-668.
    • (2009) Cell , vol.136 , pp. 656-668
    • Malone, C.D.1    Hannon, G.J.2
  • 28
    • 34447558659 scopus 로고    scopus 로고
    • piRNAs-The ancient hunters of genome invaders
    • Hartig, J.V.; Tomari, Y.; Forstemann, K. piRNAs-The ancient hunters of genome invaders. Genes Dev.2007, 21, 1707-1713.
    • (2007) Genes Dev , vol.21 , pp. 1707-1713
    • Hartig, J.V.1    Tomari, Y.2    Forstemann, K.3
  • 29
    • 67650604265 scopus 로고    scopus 로고
    • Stressing out over tRNA cleavage
    • Thompson, D.M.; Parker, R. Stressing out over tRNA cleavage. Cell 2009, 138, 215-219.
    • (2009) Cell , vol.138 , pp. 215-219
    • Thompson, D.M.1    Parker, R.2
  • 30
    • 67649382485 scopus 로고    scopus 로고
    • Dicer independent small RNAs associate with telomeric heterochromatin
    • Cao, F.; Li, X.; Hiew, S.; Brady, H.; Liu, Y.; Dou, Y. Dicer independent small RNAs associate with telomeric heterochromatin. RNA 2009, 15, 1274-1281.
    • (2009) RNA , vol.15 , pp. 1274-1281
    • Cao, F.1    Li, X.2    Hiew, S.3    Brady, H.4    Liu, Y.5    Dou, Y.6
  • 32
    • 62249133709 scopus 로고    scopus 로고
    • Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
    • Guttman, M.; Amit, I.; Garber, M.; French, C.; Lin, M.F.; Feldser, D.; Huarte, M.; Zuk, O. Carey, B.W.; Cassady, J.P.; et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009, 458, 223-227.
    • (2009) Nature , vol.458 , pp. 223-227
    • Guttman, M.1    Amit, I.2    Garber, M.3    French, C.4    Lin, M.F.5    Feldser, D.6    Huarte, M.7    Zuk, O.8    Carey, B.W.9
  • 33
    • 61849133411 scopus 로고    scopus 로고
    • Long intronic noncoding RNA transcription: Expression noise or expression choice?
    • Louro, R.; Smirnova, A.S.; Verjovski-Almeida, S. Long intronic noncoding RNA transcription: Expression noise or expression choice? Genomics 2009, 93, 291-298.
    • (2009) Genomics , vol.93 , pp. 291-298
    • Louro, R.1    Smirnova, A.S.2    Verjovski-Almeida, S.3
  • 36
    • 77952694676 scopus 로고    scopus 로고
    • Identification and analysis of unitary pseudogenes: Historic and contemporary gene losses in humans and other primates
    • Zhang, Z.D.; Frankish, A.; Hunt, T.; Harrow, J.; Gerstein, M. Identification and analysis of unitary pseudogenes: Historic and contemporary gene losses in humans and other primates. Genome Biol. 2010, 11, R26.
    • (2010) Genome Biol , vol.11
    • Zhang, Z.D.1    Frankish, A.2    Hunt, T.3    Harrow, J.4    Gerstein, M.5
  • 39
    • 69849105566 scopus 로고    scopus 로고
    • Non-coding murine centromeric transcripts associate with and potentiate aurora b kinase
    • Ferri, F.; Bouzinba-Segard, H.; Velasco, G.; Hube, F.; Francastel, C. Non-coding murine centromeric transcripts associate with and potentiate aurora b kinase. Nucleic Acids Res. 2009, 37, 5071-5080.
    • (2009) Nucleic Acids Res , vol.37 , pp. 5071-5080
    • Ferri, F.1    Bouzinba-Segard, H.2    Velasco, G.3    Hube, F.4    Francastel, C.5
  • 46
    • 58149469090 scopus 로고    scopus 로고
    • Translational control of long-lasting synaptic plasticity and memory
    • Costa-Mattioli, M.; Sossin, W.S.; Klann, E.; Sonenberg, N. Translational control of long-lasting synaptic plasticity and memory. Neuron 2009, 61, 10-26.
    • (2009) Neuron , vol.61 , pp. 10-26
    • Costa-Mattioli, M.1    Sossin, W.S.2    Klann, E.3    Sonenberg, N.4
  • 47
    • 84867499417 scopus 로고    scopus 로고
    • Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs
    • Lai, X.; Schmitz, U.; Gupta, S.K.; Bhattacharya, A.; Kunz, M.; Wolkenhauer, O.; Vera, J. Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs. Nucleic Acids Res. 2012, 40, 8818-8834.
    • (2012) Nucleic Acids Res , vol.40 , pp. 8818-8834
    • Lai, X.1    Schmitz, U.2    Gupta, S.K.3    Bhattacharya, A.4    Kunz, M.5    Wolkenhauer, O.6    Vera, J.7
  • 49
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol, J.; Loedige, I.; Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 11, 597-610.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 52
    • 84859492308 scopus 로고    scopus 로고
    • MicroRNA-130a represses transcriptional activity of aquaporin 4 mL promoter
    • Sepramaniam, S.; Ying, L.K.; Armugam, A.; Wintour, E.M.; Jeyaseelan, K. MicroRNA-130a represses transcriptional activity of aquaporin 4 mL promoter. J. Biol. Chem. 2012, 287, 12006-12015.
    • (2012) J. Biol. Chem , vol.287 , pp. 12006-12015
    • Sepramaniam, S.1    Ying, L.K.2    Armugam, A.3    Wintour, E.M.4    Jeyaseelan, K.5
  • 53
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • Mercer, T.R.; Dinger, M.E.; Mattick, J.S. Long non-coding RNAs: Insights into functions. Nat. Rev. Genet. 2009, 10, 155-159.
    • (2009) Nat. Rev. Genet , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 54
    • 84864927713 scopus 로고    scopus 로고
    • Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs
    • Moran, V.A.; Perera, R.J.; Khalil, A.M. Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs. Nucleic Acids Res. 2012, 40, 6391-6400.
    • (2012) Nucleic Acids Res , vol.40 , pp. 6391-6400
    • Moran, V.A.1    Perera, R.J.2    Khalil, A.M.3
  • 57
    • 34548291568 scopus 로고    scopus 로고
    • The mRNA-like noncoding RNA gomafu constitutes a novel nuclear domain in a subset of neurons
    • Sone, M.; Hayashi, T.; Tarui, H.; Agata, K.; Takeichi, M.; Nakagawa, S. The mRNA-like noncoding RNA gomafu constitutes a novel nuclear domain in a subset of neurons. J. Cell Sci. 2007, 120, 2498-2506.
    • (2007) J. Cell Sci , vol.120 , pp. 2498-2506
    • Sone, M.1    Hayashi, T.2    Tarui, H.3    Agata, K.4    Takeichi, M.5    Nakagawa, S.6
  • 58
    • 33744804277 scopus 로고    scopus 로고
    • The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
    • Feng, J.C.; Bi, C.M.; Clark, B.S.; Mady, R.; Shah, P.; Kohtz, J.D. The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev.2006, 20, 1470-1484.
    • (2006) Genes Dev , vol.20 , pp. 1470-1484
    • Feng, J.C.1    Bi, C.M.2    Clark, B.S.3    Mady, R.4    Shah, P.5    Kohtz, J.D.6
  • 60
    • 67649671961 scopus 로고    scopus 로고
    • Long noncoding RNAs: Functional surprises from the RNA world
    • Wilusz, J.E.; Sunwoo, H.; Spector, D.L. Long noncoding RNAs: Functional surprises from the RNA world. Genes Dev.2009, 23, 1494-1504.
    • (2009) Genes Dev , vol.23 , pp. 1494-1504
    • Wilusz, J.E.1    Sunwoo, H.2    Spector, D.L.3
  • 61
    • 58749096360 scopus 로고    scopus 로고
    • On the road to reading the RNA-interference code
    • Siomi, H.; Siomi, M.C. On the road to reading the RNA-interference code. Nature 2009, 457, 396-404.
    • (2009) Nature , vol.457 , pp. 396-404
    • Siomi, H.1    Siomi, M.C.2
  • 63
    • 33745336617 scopus 로고    scopus 로고
    • A germline-specific class of small RNAs binds mammalian Piwi proteins
    • Girard, A.; Sachidanandam, R.; Hannon, G.J.; Carmell, M.A. A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 2006, 442, 199-202.
    • (2006) Nature , vol.442 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.J.3    Carmell, M.A.4
  • 65
    • 36749037521 scopus 로고    scopus 로고
    • The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race
    • Aravin, A.A.; Hannon, G.J.; Brennecke, J. The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science 2007, 318, 761-764.
    • (2007) Science , vol.318 , pp. 761-764
    • Aravin, A.A.1    Hannon, G.J.2    Brennecke, J.3
  • 67
    • 33947273235 scopus 로고    scopus 로고
    • Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
    • Brennecke, J.; Aravin, A.A.; Stark, A.; Dus, M.; Kellis, M.; Sachidanandam, R.; Hannon, G.J. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 2007, 128, 1089-1103.
    • (2007) Cell , vol.128 , pp. 1089-1103
    • Brennecke, J.1    Aravin, A.A.2    Stark, A.3    Dus, M.4    Kellis, M.5    Sachidanandam, R.6    Hannon, G.J.7
  • 68
    • 79953089167 scopus 로고    scopus 로고
    • Piwi-interacting small RNAs: The vanguard of genome defence
    • Siomi, M.C.; Sato, K.; Pezic, D.; Aravin, A.A. Piwi-interacting small RNAs: The vanguard of genome defence. Nat. Rev. Mol. Cell Biol. 2011, 12, 246-258.
    • (2011) Nat. Rev. Mol. Cell Biol , vol.12 , pp. 246-258
    • Siomi, M.C.1    Sato, K.2    Pezic, D.3    Aravin, A.A.4
  • 69
    • 65549118489 scopus 로고    scopus 로고
    • Collapse of germline piRNAs in the absence of argonaute3 reveals somatic piRNAs in flies
    • Li, C.; Vagin, V.V.; Lee, S.; Xu, J.; Ma, S.; Xi, H.; Seitz, H.; Horwich, M.D.; Syrzycka, M.; Honda, B.M.; et al. Collapse of germline piRNAs in the absence of argonaute3 reveals somatic piRNAs in flies. Cell 2009, 137, 509-521.
    • (2009) Cell , vol.137 , pp. 509-521
    • Li, C.1    Vagin, V.V.2    Lee, S.3    Xu, J.4    Ma, S.5    Xi, H.6    Seitz, H.7    Horwich, M.D.8    Syrzycka, M.9    Honda, B.M.10
  • 72
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller, M. Non-coding RNAs in human disease. Nat. Rev. Genet. 2011, 12, 861-874.
    • (2011) Nat. Rev. Genet , vol.12 , pp. 861-874
    • Esteller, M.1
  • 73
    • 59749089928 scopus 로고    scopus 로고
    • MiRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex
    • Tonelli, D.D.; Pulvers, J.N.; Haffner, C.; Murchison, E.P.; Hannon, G.J.; Huttner, W.B. MiRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development 2008, 135, 3911-3921.
    • (2008) Development , vol.135 , pp. 3911-3921
    • Tonelli, D.D.1    Pulvers, J.N.2    Haffner, C.3    Murchison, E.P.4    Hannon, G.J.5    Huttner, W.B.6
  • 74
    • 70350708160 scopus 로고    scopus 로고
    • Different timings of dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system
    • Kawase-Koga, Y.; Otaegi, G.; Sun, T. Different timings of dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev. Dyn. 2009, 238, 2800-2812.
    • (2009) Dev. Dyn , vol.238 , pp. 2800-2812
    • Kawase-Koga, Y.1    Otaegi, G.2    Sun, T.3
  • 75
    • 43749120042 scopus 로고    scopus 로고
    • Conditional loss of dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
    • Davis, T.H.; Cuellar, T.L.; Koch, S.M.; Barker, A.J.; Harfe, B.D.; McManus, M.T.; Ullian, E.M. Conditional loss of dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J. Neurosci. 2008, 28, 4322-4330.
    • (2008) J. Neurosci , vol.28 , pp. 4322-4330
    • Davis, T.H.1    Cuellar, T.L.2    Koch, S.M.3    Barker, A.J.4    Harfe, B.D.5    McManus, M.T.6    Ullian, E.M.7
  • 78
    • 73249124152 scopus 로고    scopus 로고
    • Promotion of embryonic cortico-cerebral neuronogenesis by miR-124
    • Maiorano, N.A.; Mallamaci, A. Promotion of embryonic cortico-cerebral neuronogenesis by miR-124. Neural Dev. 2009, 4, 40.
    • (2009) Neural Dev , vol.4 , pp. 40
    • Maiorano, N.A.1    Mallamaci, A.2
  • 79
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of rest and a microRNA promote neuronal identity
    • Conaco, C.; Otto, S.; Han, J.J.; Mandel, G. Reciprocal actions of rest and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. USA 2006, 103, 2422-2427.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2422-2427
    • Conaco, C.1    Otto, S.2    Han, J.J.3    Mandel, G.4
  • 80
    • 34147157651 scopus 로고    scopus 로고
    • The microRNA miR-124 antagonizes the nti-neural REST/SCP1 pathway during embryonic CNS development
    • Visvanathan, J.; Lee, S.; Lee, B.; Lee, J.W.; Lee, S.K. The microRNA miR-124 antagonizes the nti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev.2007, 21, 744-749.
    • (2007) Genes Dev , vol.21 , pp. 744-749
    • Visvanathan, J.1    Lee, S.2    Lee, B.3    Lee, J.W.4    Lee, S.K.5
  • 81
    • 34547212309 scopus 로고    scopus 로고
    • The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev, E.V.; Zhang, J.; Carrasco, M.A.; Maniatis, T. The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 2007, 27, 435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 82
    • 80052049272 scopus 로고    scopus 로고
    • MicroRNA profiling in subventricular zone after stroke: MiR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway
    • Liu, X.S.; Chopp, M.; Zhang, R.L.; Tao, T.; Wang, X.L.; Kassis, H.; Hozeska-Solgot, A.; Zhang, L.; Chen, C.; Zhang, Z.G. MicroRNA profiling in subventricular zone after stroke: miR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway. PLoS One 2011, 6, e23461.
    • (2011) PLoS One , vol.e23461 , pp. 6
    • Liu, X.S.1    Chopp, M.2    Zhang, R.L.3    Tao, T.4    Wang, X.L.5    Kassis, H.6    Hozeska-Solgot, A.7    Zhang, L.8    Chen, C.9    Zhang, Z.G.10
  • 85
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
    • Deo, M.; Yu, J.Y.; Chung, K.H.; Tippens, M.; Turner, D.L. Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn. 2006, 235, 2538-2548.
    • (2006) Dev. Dyn , vol.235 , pp. 2538-2548
    • Deo, M.1    Yu, J.Y.2    Chung, K.H.3    Tippens, M.4    Turner, D.L.5
  • 86
    • 58149375393 scopus 로고    scopus 로고
    • The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
    • Packer, A.N.; Xing, Y.; Harper, S.Q.; Jones, L.; Davidson, B.L. The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci. 2008, 28, 14341-14346.
    • (2008) J. Neurosci , vol.28 , pp. 14341-14346
    • Packer, A.N.1    Xing, Y.2    Harper, S.Q.3    Jones, L.4    Davidson, B.L.5
  • 87
    • 64049095014 scopus 로고    scopus 로고
    • A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination
    • Zhao, C.; Sun, G.Q.; Li, S.X.; Shi, Y.H. A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat. Struct. Mol. Biol. 2009, 16, 365-371.
    • (2009) Nat. Struct. Mol. Biol , vol.16 , pp. 365-371
    • Zhao, C.1    Sun, G.Q.2    Li, S.X.3    Shi, Y.H.4
  • 88
    • 77949903674 scopus 로고    scopus 로고
    • MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors
    • Delaloy, C.; Liu, L.; Lee, J.A.; Su, H.; Shen, F.; Yang, G.Y.; Young, W.L.; Ivey, K.N.; Gao, F.B. MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell 2010, 6, 323-335.
    • (2010) Cell Stem Cell , vol.6 , pp. 323-335
    • Delaloy, C.1    Liu, L.2    Lee, J.A.3    Su, H.4    Shen, F.5    Yang, G.Y.6    Young, W.L.7    Ivey, K.N.8    Gao, F.B.9
  • 89
    • 79952267171 scopus 로고    scopus 로고
    • MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors
    • Shibata, M.; Nakao, H.; Kiyonari, H.; Abe, T.; Aizawa, S. MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J. Neurosci. 2011, 31, 3407-3422.
    • (2011) J. Neurosci , vol.31 , pp. 3407-3422
    • Shibata, M.1    Nakao, H.2    Kiyonari, H.3    Abe, T.4    Aizawa, S.5
  • 90
    • 84860284308 scopus 로고    scopus 로고
    • MicroRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons
    • Dajas-Bailador, F.; Bonev, B.; Garcez, P.; Stanley, P.; Guillemot, F.; Papalopulu, N. MicroRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons. Nat. Neurosci. 2012, 15, 697-699.
    • (2012) Nat. Neurosci , vol.15 , pp. 697-699
    • Dajas-Bailador, F.1    Bonev, B.2    Garcez, P.3    Stanley, P.4    Guillemot, F.5    Papalopulu, N.6
  • 92
    • 79960752625 scopus 로고    scopus 로고
    • Stage-specific modulation of cortical neuronal development by Mmu-miR-134
    • Gaughwin, P.; Ciesla, M.; Yang, H.; Lim, B.; Brundin, P. Stage-specific modulation of cortical neuronal development by Mmu-miR-134. Cereb. Cortex 2011, 21, 1857-1869.
    • (2011) Cereb. Cortex , vol.21 , pp. 1857-1869
    • Gaughwin, P.1    Ciesla, M.2    Yang, H.3    Lim, B.4    Brundin, P.5
  • 94
    • 62649086993 scopus 로고    scopus 로고
    • Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels
    • Fiore, R.; Khudayberdiev, S.; Christensen, M.; Siegel, G.; Flavell, S.W.; Kim, T.K.; Greenberg, M.E.; Schratt, G. Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 2009, 28, 697-710.
    • (2009) EMBO J , vol.28 , pp. 697-710
    • Fiore, R.1    Khudayberdiev, S.2    Christensen, M.3    Siegel, G.4    Flavell, S.W.5    Kim, T.K.6    Greenberg, M.E.7    Schratt, G.8
  • 95
    • 78651511540 scopus 로고    scopus 로고
    • miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis
    • Kole, A.J.; Swahari, V.; Hammond, S.M.; Deshmukh, M. miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis. Genes Dev.2011, 25, 125-130.
    • (2011) Genes Dev , vol.25 , pp. 125-130
    • Kole, A.J.1    Swahari, V.2    Hammond, S.M.3    Deshmukh, M.4
  • 96
    • 52949127993 scopus 로고    scopus 로고
    • Novel noncoding antisense RNA transcribed from human anti-NOS2A locus is differentially regulated during neuronal differentiation of embryonic stem cells
    • Korneev, S.A.; Korneeva, E.I.; Lagarkova, M.A.; Kiselev, S.L.; Critchley, G.; O'Shea, M. Novel noncoding antisense RNA transcribed from human anti-NOS2A locus is differentially regulated during neuronal differentiation of embryonic stem cells. RNA 2008, 14, 2030-2037.
    • (2008) RNA , vol.14 , pp. 2030-2037
    • Korneev, S.A.1    Korneeva, E.I.2    Lagarkova, M.A.3    Kiselev, S.L.4    Critchley, G.5    O'Shea, M.6
  • 97
    • 79951837277 scopus 로고    scopus 로고
    • Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis
    • Ling, K.H.; Hewitt, C.A.; Beissbarth, T.; Hyde, L.; Cheah, P.S.; Smyth, G.K.; Tan, S.S.; Hahn, C.N.; Thomas, T.; Thomas, P.Q.; et al. Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis. Cereb. Cortex 2011, 21, 683-697.
    • (2011) Cereb. Cortex , vol.21 , pp. 683-697
    • Ling, K.H.1    Hewitt, C.A.2    Beissbarth, T.3    Hyde, L.4    Cheah, P.S.5    Smyth, G.K.6    Tan, S.S.7    Hahn, C.N.8    Thomas, T.9    Thomas, P.Q.10
  • 98
    • 67949083572 scopus 로고    scopus 로고
    • MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
    • Yoo, A.S.; Staahl, B.T.; Chen, L.; Crabtree, G.R. MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 2009, 460, 642-646.
    • (2009) Nature , vol.460 , pp. 642-646
    • Yoo, A.S.1    Staahl, B.T.2    Chen, L.3    Crabtree, G.R.4
  • 100
    • 80053444842 scopus 로고    scopus 로고
    • Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain
    • Anguera, M.C.; Ma, W.Y.; Clift, D.; Namekawa, S.; Kelleher, R.J.; Lee, J.T. Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain. PLoS Genet. 2011, 7, e1002248.
    • (2011) PLoS Genet , vol.e1002248 , pp. 7
    • Anguera, M.C.1    Ma, W.Y.2    Clift, D.3    Namekawa, S.4    Kelleher, R.J.5    Lee, J.T.6
  • 102
  • 103
    • 0029919678 scopus 로고    scopus 로고
    • Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated
    • Li, A.W.; Seyoum, G.; Shiu, R.P.C.; Murphy, P.R. Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated. Mol. Cell. Endorinol. 1996, 118, 113-123.
    • (1996) Mol. Cell. Endorinol , vol.118 , pp. 113-123
    • Li, A.W.1    Seyoum, G.2    Shiu, R.P.C.3    Murphy, P.R.4
  • 104
    • 0034704473 scopus 로고    scopus 로고
    • Expression of alternatively spliced FGF-2 antisense RNA transcripts in the central nervous system: Regulation of FGF-2 mRNA translation
    • Li, A.W.; Murphy, P.R. Expression of alternatively spliced FGF-2 antisense RNA transcripts in the central nervous system: Regulation of FGF-2 mRNA translation. Mol. Cell. Endorinol. 2000, 170, 233-242.
    • (2000) Mol. Cell. Endorinol , vol.170 , pp. 233-242
    • Li, A.W.1    Murphy, P.R.2
  • 105
    • 84855359363 scopus 로고    scopus 로고
    • Variants on chromosome 9p21.3 correlated with ANRIL expression contribute to stroke risk and recurrence in a large prospective stroke population
    • Zhang, W.; Chen, Y.; Liu, P.; Chen, J.; Song, L.; Tang, Y.; Wang, Y.; Liu, J.; Hu, F.B.; Hui, R. Variants on chromosome 9p21.3 correlated with ANRIL expression contribute to stroke risk and recurrence in a large prospective stroke population. Stroke 2012, 43, 14-21.
    • (2012) Stroke , vol.43 , pp. 14-21
    • Zhang, W.1    Chen, Y.2    Liu, P.3    Chen, J.4    Song, L.5    Tang, Y.6    Wang, Y.7    Liu, J.8    Hu, F.B.9    Hui, R.10
  • 107
  • 108
    • 79952255050 scopus 로고    scopus 로고
    • Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5
    • Hawkins, P.G.; Morris, K.V. Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5. Transcription 2010, 1, 165-175.
    • (2010) Transcription , vol.1 , pp. 165-175
    • Hawkins, P.G.1    Morris, K.V.2
  • 114
    • 58149379604 scopus 로고    scopus 로고
    • MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons
    • Aschrafi, A.; Schwechter, A.D.; Mameza, M.G.; Natera-Naranjo, O.; Gioio, A.E.; Kaplan, B.B. MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons. J. Neurosci. 2008, 28, 12581-12590.
    • (2008) J. Neurosci , vol.28 , pp. 12581-12590
    • Aschrafi, A.1    Schwechter, A.D.2    Mameza, M.G.3    Natera-Naranjo, O.4    Gioio, A.E.5    Kaplan, B.B.6
  • 118
    • 72149086111 scopus 로고    scopus 로고
    • A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation
    • Banerjee, S.; Neveu, P.; Kosik, K.S. A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation. Neuron 2009, 64, 871-884.
    • (2009) Neuron , vol.64 , pp. 871-884
    • Banerjee, S.1    Neveu, P.2    Kosik, K.S.3
  • 122
    • 82255169289 scopus 로고    scopus 로고
    • Downregulation of miR-199a may play a role in 3-nitropropionic acid induced ischemic tolerance in rat brain
    • Xu, W.H.; Yao, X.Y.; Yu, H.J.; Huang, J.W.; Cui, L.Y. Downregulation of miR-199a may play a role in 3-nitropropionic acid induced ischemic tolerance in rat brain. Brain Res. 2012, 1429, 116-123.
    • (2012) Brain Res , vol.1429 , pp. 116-123
    • Xu, W.H.1    Yao, X.Y.2    Yu, H.J.3    Huang, J.W.4    Cui, L.Y.5
  • 123
    • 65249185780 scopus 로고    scopus 로고
    • Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes
    • Rane, S.; He, M.; Sayed, D.; Vashistha, H.; Malhotra, A.; Sadoshima, J.; Vatner, D.E.; Vatner, S.F.; Abdellatif, M. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ. Res. 2009, 104, 879-886.
    • (2009) Circ. Res , vol.104 , pp. 879-886
    • Rane, S.1    He, M.2    Sayed, D.3    Vashistha, H.4    Malhotra, A.5    Sadoshima, J.6    Vatner, D.E.7    Vatner, S.F.8    Abdellatif, M.9
  • 125
    • 48649102010 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster
    • Taguchi, A.; Yanagisawa, K.; Tanaka, M.; Cao, K.; Matsuyama, Y.; Goto, H.; Takahashi, T. Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster. Cancer Res. 2008, 68, 5540-5545.
    • (2008) Cancer Res , vol.68 , pp. 5540-5545
    • Taguchi, A.1    Yanagisawa, K.2    Tanaka, M.3    Cao, K.4    Matsuyama, Y.5    Goto, H.6    Takahashi, T.7
  • 126
    • 0033585496 scopus 로고    scopus 로고
    • aHIF: A natural antisense transcript overexpressed in human renal cancer and during hypoxia
    • Thrash-Bingham, C.A.; Tartof, K.D. aHIF: A natural antisense transcript overexpressed in human renal cancer and during hypoxia. J. Natl. Cancer Inst. 1999, 91, 143-151.
    • (1999) J. Natl. Cancer Inst , vol.91 , pp. 143-151
    • Thrash-Bingham, C.A.1    Tartof, K.D.2
  • 128
    • 23044479387 scopus 로고    scopus 로고
    • Characterization of hypoxia induced gene 1: Expression during rat central nervous system maturation and evidence of antisense RNA expression
    • Bedo, G.; Vargas, M.; Ferreiro, M.J.; Chalar, C.; Agrati, D. Characterization of hypoxia induced gene 1: Expression during rat central nervous system maturation and evidence of antisense RNA expression. Int. J. Dev. Biol. 2005, 49, 431-436.
    • (2005) Int. J. Dev. Biol , vol.49 , pp. 431-436
    • Bedo, G.1    Vargas, M.2    Ferreiro, M.J.3    Chalar, C.4    Agrati, D.5
  • 129
    • 84863229770 scopus 로고    scopus 로고
    • miR-138 suppresses expression of hypoxia-inducible factor 1alpha (HIF-1alpha) in clear cell renal cell carcinoma 786-O cells
    • Song, T.; Zhang, X.; Wang, C.; Wu, Y.; Cai, W.; Gao, J.; Hong, B. miR-138 suppresses expression of hypoxia-inducible factor 1alpha (HIF-1alpha) in clear cell renal cell carcinoma 786-O cells. Asian Pac. J. Cancer Prev. 2011, 12, 1307-1311.
    • (2011) Asian Pac. J. Cancer Prev , vol.12 , pp. 1307-1311
    • Song, T.1    Zhang, X.2    Wang, C.3    Wu, Y.4    Cai, W.5    Gao, J.6    Hong, B.7
  • 130
  • 131
    • 77950881915 scopus 로고    scopus 로고
    • Oncofetal h19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer
    • Tsang, W.P.; Ng, E.K.; Ng, S.S.; Jin, H.; Yu, J.; Sung, J.J.; Kwok, T.T. Oncofetal h19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis 2010, 31, 350-358.
    • (2010) Carcinogenesis , vol.31 , pp. 350-358
    • Tsang, W.P.1    Ng, E.K.2    Ng, S.S.3    Jin, H.4    Yu, J.5    Sung, J.J.6    Kwok, T.T.7
  • 132
    • 84863661526 scopus 로고    scopus 로고
    • MicroRNA 107 partly inhibits endothelial progenitor cells differentiation via HIF-1beta
    • Meng, S.; Cao, J.; Wang, L.; Zhou, Q.; Li, Y.; Shen, C.; Zhang, X.; Wang, C. MicroRNA 107 partly inhibits endothelial progenitor cells differentiation via HIF-1beta. PLoS One 2012, 7, e40323.
    • (2012) PLoS One , vol.e40323 , pp. 7
    • Meng, S.1    Cao, J.2    Wang, L.3    Zhou, Q.4    Li, Y.5    Shen, C.6    Zhang, X.7    Wang, C.8
  • 133
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno, L.; Salmena, L.; Zhang, J.; Carver, B.; Haveman, W.J.; Pandolfi, P.P. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010, 465, 1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 134
    • 70449602451 scopus 로고    scopus 로고
    • Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration
    • Lei, Z.; Li, B.; Yang, Z.; Fang, H.; Zhang, G.M.; Feng, Z.H.; Huang, B. Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS One 2009, 4, e7629.
    • (2009) PLoS One , vol.e7629 , pp. 4
    • Lei, Z.1    Li, B.2    Yang, Z.3    Fang, H.4    Zhang, G.M.5    Feng, Z.H.6    Huang, B.7
  • 135
    • 84873564989 scopus 로고    scopus 로고
    • miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF
    • Sun, C.Y.; She, X.M.; Qin, Y.; Chu, Z.B.; Chen, L.; Ai, L.S.; Zhang, L.; Hu, Y. miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF. Carcinogenesis 2012, 34, 426-235.
    • (2012) Carcinogenesis , vol.34 , pp. 426-435
    • Sun, C.Y.1    She, X.M.2    Qin, Y.3    Chu, Z.B.4    Chen, L.5    Ai, L.S.6    Zhang, L.7    Hu, Y.8
  • 137
    • 77954941124 scopus 로고    scopus 로고
    • Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions
    • Long, J.Y.; Wang, Y.; Wang, W.J.; Chang, B.H.J.; Danesh, F.R. Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions. J. Biol. Chem. 2010, 285, 23455-23463.
    • (2010) J. Biol. Chem , vol.285 , pp. 23455-23463
    • Long, J.Y.1    Wang, Y.2    Wang, W.J.3    Chang, B.H.J.4    Danesh, F.R.5
  • 145
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov, K.D.; Boldin, M.P.; Chang, K.J.; Baltimore, D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. USA 2006, 103, 12481-12486.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 146
    • 78650594380 scopus 로고    scopus 로고
    • 17a, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease
    • Massone, S.; Vassallo, I.; Fiorino, G.; Castelnuovo, M.; Barbieri, F.; Borghi, R.; Tabaton, M.; Robello, M.; Gatta, E.; Russo, C.; et al. 17a, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease. Neurobiol. Dis. 2011, 41, 308-317.
    • (2011) Neurobiol. Dis , vol.41 , pp. 308-317
    • Massone, S.1    Vassallo, I.2    Fiorino, G.3    Castelnuovo, M.4    Barbieri, F.5    Borghi, R.6    Tabaton, M.7    Robello, M.8    Gatta, E.9    Russo, C.10
  • 147
    • 79952575527 scopus 로고    scopus 로고
    • MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4
    • Yang, K.; He, Y.S.; Wang, X.Q.; Lu, L.; Chen, Q.J.; Liu, J.; Sun, Z.; Shen, W.F. MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4. FEBS Lett. 2011, 585, 854-860.
    • (2011) FEBS Lett , vol.585 , pp. 854-860
    • Yang, K.1    He, Y.S.2    Wang, X.Q.3    Lu, L.4    Chen, Q.J.5    Liu, J.6    Sun, Z.7    Shen, W.F.8
  • 148
    • 84865798747 scopus 로고    scopus 로고
    • The microRNA miR-181c controls microglia-mediated neuronal apoptosis by suppressing tumor necrosis factor
    • Zhang, L.; Dong, L.Y.; Li, Y.J.; Hong, Z.; Wei, W.S. The microRNA miR-181c controls microglia-mediated neuronal apoptosis by suppressing tumor necrosis factor. J. Neuroinflammation 2012, 9, 211.
    • (2012) J. Neuroinflammation , vol.9 , pp. 211
    • Zhang, L.1    Dong, L.Y.2    Li, Y.J.3    Hong, Z.4    Wei, W.S.5
  • 149
    • 38049030287 scopus 로고    scopus 로고
    • Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
    • Tili, E.; Michaille, J.J.; Cimino, A.; Costinean, S.; Dumitru, C.D.; Adair, B.; Fabbri, M.; Alder, H.; Liu, C.G.; Calin, G.A.; et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J. Immunol. 2007, 179, 5082-5089.
    • (2007) J. Immunol , vol.179 , pp. 5082-5089
    • Tili, E.1    Michaille, J.J.2    Cimino, A.3    Costinean, S.4    Dumitru, C.D.5    Adair, B.6    Fabbri, M.7    Alder, H.8    Liu, C.G.9    Calin, G.A.10
  • 150
    • 73949113629 scopus 로고    scopus 로고
    • Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: Feedback control of inflammation
    • Suarez, Y.; Wang, C.; Manes, T.D.; Pober, J.S. Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: Feedback control of inflammation. J. Immunol. 2010, 184, 21-25.
    • (2010) J. Immunol , vol.184 , pp. 21-25
    • Suarez, Y.1    Wang, C.2    Manes, T.D.3    Pober, J.S.4
  • 152
    • 63949084047 scopus 로고    scopus 로고
    • Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome
    • Dharap, A.; Bowen, K.; Place, R.; Li, L.C.; Vemuganti, R. Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome. J. Cereb. Blood Flow Metab. 2009, 29, 675-687.
    • (2009) J. Cereb. Blood Flow Metab , vol.29 , pp. 675-687
    • Dharap, A.1    Bowen, K.2    Place, R.3    Li, L.C.4    Vemuganti, R.5
  • 153
    • 40449114449 scopus 로고    scopus 로고
    • A novel noncoding RNA rescues mutant SOD1-mediated cell death
    • Chang, Y.M.; Stockinger, M.P.; Tashiro, H.; Lin, C.L.G. A novel noncoding RNA rescues mutant SOD1-mediated cell death. FASEB J. 2008, 22, 691-702.
    • (2008) FASEB J , vol.22 , pp. 691-702
    • Chang, Y.M.1    Stockinger, M.P.2    Tashiro, H.3    Lin, C.L.G.4
  • 155
    • 65549103396 scopus 로고    scopus 로고
    • The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress
    • Brookheart, R.T.; Michel, C.I.; Listenberger, L.L.; Ory, D.S.; Schaffer, J.E. The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress. J. Biol. Chem. 2009, 284, 7446-7454.
    • (2009) J. Biol. Chem , vol.284 , pp. 7446-7454
    • Brookheart, R.T.1    Michel, C.I.2    Listenberger, L.L.3    Ory, D.S.4    Schaffer, J.E.5
  • 156
    • 77951793925 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury
    • Yin, K.J.; Deng, Z.; Hamblin, M.; Xiang, Y.; Huang, H.; Zhang, J.; Jiang, X.; Wang, Y.; Chen, Y.E. Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury. J. Neurosci. 2010, 30, 6398-6408.
    • (2010) J. Neurosci , vol.30 , pp. 6398-6408
    • Yin, K.J.1    Deng, Z.2    Hamblin, M.3    Xiang, Y.4    Huang, H.5    Zhang, J.6    Jiang, X.7    Wang, Y.8    Chen, Y.E.9
  • 157
  • 158
    • 84856250463 scopus 로고    scopus 로고
    • Upregulated miR-29b promotes neuronal cell death by inhibiting Bcl2L2 after ischemic brain injury
    • Shi, G.; Liu, Y.; Liu, T.; Yan, W.; Liu, X.; Wang, Y.; Shi, J.; Jia, L. Upregulated miR-29b promotes neuronal cell death by inhibiting Bcl2L2 after ischemic brain injury. Exp. Brain Res. 2012, 216, 225-230.
    • (2012) Exp. Brain Res , vol.216 , pp. 225-230
    • Shi, G.1    Liu, Y.2    Liu, T.3    Yan, W.4    Liu, X.5    Wang, Y.6    Shi, J.7    Jia, L.8
  • 160
    • 0037222287 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase after focal cerebral ischemia stimulates neurogenesis in the adult rodent dentate gyrus
    • Zhu, D.Y.; Liu, S.H.; Sun, H.S.; Lu, Y.M. Expression of inducible nitric oxide synthase after focal cerebral ischemia stimulates neurogenesis in the adult rodent dentate gyrus. J. Neurosci. 2003, 23, 223-229.
    • (2003) J. Neurosci , vol.23 , pp. 223-229
    • Zhu, D.Y.1    Liu, S.H.2    Sun, H.S.3    Lu, Y.M.4
  • 161
    • 49049092989 scopus 로고    scopus 로고
    • The effects of retinoic acid on the expression of neurogranin after experimental cerebral ischemia
    • Li, L.; Li, Y.; Ji, X.; Zhang, B.; Wei, H.; Luo, Y. The effects of retinoic acid on the expression of neurogranin after experimental cerebral ischemia. Brain Res. 2008, 1226, 234-240.
    • (2008) Brain Res , vol.1226 , pp. 234-240
    • Li, L.1    Li, Y.2    Ji, X.3    Zhang, B.4    Wei, H.5    Luo, Y.6
  • 162
    • 77953176824 scopus 로고    scopus 로고
    • Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury
    • Ryge, J.; Winther, O.; Wienecke, J.; Sandelin, A.; Westerdahl, A.C.; Hultborn, H.; Kiehn, O. Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury. BMC Genomics 2010, 11, 365.
    • (2010) BMC Genomics , vol.11 , pp. 365
    • Ryge, J.1    Winther, O.2    Wienecke, J.3    Sandelin, A.4    Westerdahl, A.C.5    Hultborn, H.6    Kiehn, O.7
  • 163
    • 0030678532 scopus 로고    scopus 로고
    • Induction of basic fibroblast growth factor (BFGF) expression following focal cerebral ischemia
    • Lin, T.N.; Te, J.; Lee, M.; Sun, G.Y.; Hsu, C.Y. Induction of basic fibroblast growth factor (BFGF) expression following focal cerebral ischemia. Brain Res. Mol. Brain Res. 1997, 49, 255-265.
    • (1997) Brain Res. Mol. Brain Res , vol.49 , pp. 255-265
    • Lin, T.N.1    Te, J.2    Lee, M.3    Sun, G.Y.4    Hsu, C.Y.5
  • 164
    • 75349113672 scopus 로고    scopus 로고
    • Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling
    • Ling, K.H.; Hewitt, C.A.; Beissbarth, T.; Hyde, L.; Banerjee, K.; Cheah, P.S.; Cannon, P.Z.; Hahn, C.N.; Thomas, P.Q.; Smyth, G.K.; et al. Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Genome Biol. 2009, 10, R104.
    • (2009) Genome Biol , vol.10
    • Ling, K.H.1    Hewitt, C.A.2    Beissbarth, T.3    Hyde, L.4    Banerjee, K.5    Cheah, P.S.6    Cannon, P.Z.7    Hahn, C.N.8    Thomas, P.Q.9    Smyth, G.K.10
  • 165
    • 32244433670 scopus 로고    scopus 로고
    • Novel transcription factor zfh-5 is negatively regulated by its own antisense RNA in mouse brain
    • Komine, Y.; Nakamura, K.; Katsuki, M.; Yamamori, T. Novel transcription factor zfh-5 is negatively regulated by its own antisense RNA in mouse brain. Mol. Cell. Neurosci. 2006, 31, 273-283.
    • (2006) Mol. Cell. Neurosci , vol.31 , pp. 273-283
    • Komine, Y.1    Nakamura, K.2    Katsuki, M.3    Yamamori, T.4
  • 166
    • 77952541654 scopus 로고    scopus 로고
    • The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage
    • Kerr, N.; Pintzas, A.; Holmes, F.; Hobson, S.A.; Pope, R.; Wallace, M.; Wasylyk, C.; Wasylyk, B.; Wynick, D. The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage. Mol. Cell. Neurosci. 2010, 44, 165-177.
    • (2010) Mol. Cell. Neurosci , vol.44 , pp. 165-177
    • Kerr, N.1    Pintzas, A.2    Holmes, F.3    Hobson, S.A.4    Pope, R.5    Wallace, M.6    Wasylyk, C.7    Wasylyk, B.8    Wynick, D.9
  • 167
    • 75149163987 scopus 로고    scopus 로고
    • Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells
    • Mohamed, J.S.; Gaughwin, P.M.; Lim, B.; Robson, P.; Lipovich, L. Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA 2010, 16, 324-337.
    • (2010) RNA , vol.16 , pp. 324-337
    • Mohamed, J.S.1    Gaughwin, P.M.2    Lim, B.3    Robson, P.4    Lipovich, L.5
  • 168
    • 84860320656 scopus 로고    scopus 로고
    • A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity
    • Rajasethupathy, P.; Antonov, I.; Sheridan, R.; Frey, S.; Sander, C.; Tuschl, T.; Kandel, E.R. A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell 2012, 149, 693-707.
    • (2012) Cell , vol.149 , pp. 693-707
    • Rajasethupathy, P.1    Antonov, I.2    Sheridan, R.3    Frey, S.4    Sander, C.5    Tuschl, T.6    Kandel, E.R.7
  • 169
    • 0022970945 scopus 로고
    • Preconditioning with ischemia-A delay of lethal cell injury in ischemic myocardium
    • Murry, C.E.; Jennings, R.B.; Reimer, K.A. Preconditioning with ischemia-A delay of lethal cell injury in ischemic myocardium. Circulation 1986, 74, 1124-1136.
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 171
    • 0038060334 scopus 로고    scopus 로고
    • Ischemic tolerance and endogenous neuroprotection
    • DiRNAgl, U.; Simon, R.P.; Hallenbeck, J.M. Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 2003, 26, 248-254.
    • (2003) Trends Neurosci , vol.26 , pp. 248-254
    • Dirnagl, U.1    Simon, R.P.2    Hallenbeck, J.M.3
  • 172
    • 42049108814 scopus 로고    scopus 로고
    • Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury
    • Murphy, E.; Steenbergen, C. Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol. Rev. 2008, 88, 581-609.
    • (2008) Physiol. Rev , vol.88 , pp. 581-609
    • Murphy, E.1    Steenbergen, C.2
  • 173
    • 0036487283 scopus 로고    scopus 로고
    • Alpha-adrenergic receptor stimulation produces late preconditioning through inducible nitric oxide synthase in mouse heart
    • Tejero-Taldo, M.I.; Gursoy, E.; Zhao, T.C.; Kukreja, R.C. Alpha-adrenergic receptor stimulation produces late preconditioning through inducible nitric oxide synthase in mouse heart. J. Mol. Cell. Cardiol. 2002, 34, 185-195.
    • (2002) J. Mol. Cell. Cardiol , vol.34 , pp. 185-195
    • Tejero-Taldo, M.I.1    Gursoy, E.2    Zhao, T.C.3    Kukreja, R.C.4
  • 175
    • 27744577465 scopus 로고    scopus 로고
    • Late preconditioning with isoflurane in cultured rat cortical neurones
    • Kaneko, T.; Yokoyama, K.; Makita, K. Late preconditioning with isoflurane in cultured rat cortical neurones. Br. J. Anaesth. 2005, 95, 662-668.
    • (2005) Br. J. Anaesth , vol.95 , pp. 662-668
    • Kaneko, T.1    Yokoyama, K.2    Makita, K.3
  • 176
    • 77953101936 scopus 로고    scopus 로고
    • Ischemic preconditioning alters cerebral microRNAs that are upstream to neuroprotective signaling pathways
    • Dharap, A.; Vemuganti, R. Ischemic preconditioning alters cerebral microRNAs that are upstream to neuroprotective signaling pathways. J. Neurochem. 2010, 113, 1685-1691.
    • (2010) J. Neurochem , vol.113 , pp. 1685-1691
    • Dharap, A.1    Vemuganti, R.2
  • 178
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • Mehta, S.L.; Manhas, N.; Raghubir, R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res. Rev. 2007, 54, 34-66.
    • (2007) Brain Res. Rev , vol.54 , pp. 34-66
    • Mehta, S.L.1    Manhas, N.2    Raghubir, R.3
  • 183
    • 79954895374 scopus 로고    scopus 로고
    • Altered expression of piwi RNA in the rat brain after transient focal ischemia
    • Dharap, A.; Nakka, V.P.; Vemuganti, R. Altered expression of piwi RNA in the rat brain after transient focal ischemia. Stroke 2011, 42, 1105-1109.
    • (2011) Stroke , vol.42 , pp. 1105-1109
    • Dharap, A.1    Nakka, V.P.2    Vemuganti, R.3
  • 184
    • 0035863870 scopus 로고    scopus 로고
    • Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi
    • Sharma, A.K.; Nelson, M.C.; Brandt, J.E.; Wessman, M.; Mahmud, N.; Weller, K.P.; Hoffman, R. Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Blood 2001, 97, 426-434.
    • (2001) Blood , vol.97 , pp. 426-434
    • Sharma, A.K.1    Nelson, M.C.2    Brandt, J.E.3    Wessman, M.4    Mahmud, N.5    Weller, K.P.6    Hoffman, R.7
  • 185
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
    • Semenza, G.L. HIF-1: Mediator of physiological and pathophysiological responses to hypoxia. J. Appl. Physiol. 2000, 88, 1474-1480.
    • (2000) J. Appl. Physiol , vol.88 , pp. 1474-1480
    • Semenza, G.L.1
  • 186
    • 0038037735 scopus 로고    scopus 로고
    • Regulation of angiogenesis by hypoxia: Role of the HIF system
    • Pugh, C.W.; Ratcliffe, P.J. Regulation of angiogenesis by hypoxia: Role of the HIF system. Nat. Med. 2003, 9, 677-684.
    • (2003) Nat. Med , vol.9 , pp. 677-684
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 187
    • 0032052727 scopus 로고    scopus 로고
    • Erythropoietin: A model system for studying oxygen-dependent gene regulation
    • Bunn, H.F.; Gu, J.; Huang, L.E.; Park, J.W.; Zhu, H. Erythropoietin: A model system for studying oxygen-dependent gene regulation. J. Exp. Biol. 1998, 201, 1197-1201.
    • (1998) J. Exp. Biol , vol.201 , pp. 1197-1201
    • Bunn, H.F.1    Gu, J.2    Huang, L.E.3    Park, J.W.4    Zhu, H.5
  • 188
    • 84855941030 scopus 로고    scopus 로고
    • Roles for HIF-1alpha in neural stem cell function and the regenerative response to stroke
    • Cunningham, L.A.; Candelario, K.; Li, L. Roles for HIF-1alpha in neural stem cell function and the regenerative response to stroke. Behav. Brain Res. 2012, 227, 410-417.
    • (2012) Behav. Brain Res , vol.227 , pp. 410-417
    • Cunningham, L.A.1    Candelario, K.2    Li, L.3
  • 189
    • 0242330181 scopus 로고    scopus 로고
    • Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor
    • Bruick, R.K. Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor. Genes Dev.2003, 17, 2614-2623.
    • (2003) Genes Dev , vol.17 , pp. 2614-2623
    • Bruick, R.K.1
  • 190
    • 0030583293 scopus 로고    scopus 로고
    • In vivo expression of mRNAs encoding hypoxia-inducible factor 1
    • Wiener, C.M.; Booth, G.; Semenza, G.L. In vivo expression of mRNAs encoding hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun. 1996, 225, 485-488.
    • (1996) Biochem. Biophys. Res. Commun , vol.225 , pp. 485-488
    • Wiener, C.M.1    Booth, G.2    Semenza, G.L.3
  • 191
    • 0033435198 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
    • Bergeron, M.; Yu, A.Y.; Solway, K.E.; Semenza, G.L.; Sharp, F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 1999, 11, 4159-4170.
    • (1999) Eur. J. Neurosci , vol.11 , pp. 4159-4170
    • Bergeron, M.1    Yu, A.Y.2    Solway, K.E.3    Semenza, G.L.4    Sharp, F.R.5
  • 192
    • 79954594089 scopus 로고    scopus 로고
    • Selective inhibition of early-but not late-expressed HIF-1 alpha is neuroprotective in rats after focal ischemic brain damage
    • Yeh, S.H.; Ou, L.C.; Gean, P.W.; Hung, J.J.; Chang, W.C. Selective inhibition of early-but not late-expressed HIF-1 alpha is neuroprotective in rats after focal ischemic brain damage. Brain Pathol. 2011, 21, 249-262.
    • (2011) Brain Pathol , vol.21 , pp. 249-262
    • Yeh, S.H.1    Ou, L.C.2    Gean, P.W.3    Hung, J.J.4    Chang, W.C.5
  • 193
    • 54049105673 scopus 로고    scopus 로고
    • Hypoxia response and microRNAs: No longer two separate worlds
    • Ivan, M.; Harris, A.L.; Martelli, F.; Kulshreshtha, R. Hypoxia response and microRNAs: No longer two separate worlds. J. Cell. Mol. Med. 2008, 12, 1426-1431.
    • (2008) J. Cell. Mol. Med , vol.12 , pp. 1426-1431
    • Ivan, M.1    Harris, A.L.2    Martelli, F.3    Kulshreshtha, R.4
  • 194
    • 45549086958 scopus 로고    scopus 로고
    • Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-a3 and neuronal pentraxin 1 are potentially regulated by miR-210
    • Pulkkinen, K.; Malm, T.; Turunen, M.; Koistinaho, J.; Yla-Herttuala, S. Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-a3 and neuronal pentraxin 1 are potentially regulated by miR-210. FEBS Lett. 2008, 582, 2397-2401.
    • (2008) FEBS Lett , vol.582 , pp. 2397-2401
    • Pulkkinen, K.1    Malm, T.2    Turunen, M.3    Koistinaho, J.4    Yla-Herttuala, S.5
  • 198
    • 0036807952 scopus 로고    scopus 로고
    • cDNA microarray analysis of changes in gene expression induced by neuronal hypoxia in vitro
    • Jin, K.; Mao, X.O.; Eshoo, M.W.; del Rio, G.; Rao, R.; Chen, D.; Simon, R.P.; Greenberg, D.A. cDNA microarray analysis of changes in gene expression induced by neuronal hypoxia in vitro. Neurochem. Res. 2002, 27, 1105-1112.
    • (2002) Neurochem. Res , vol.27 , pp. 1105-1112
    • Jin, K.1    Mao, X.O.2    Eshoo, M.W.3    del, R.G.4    Rao, R.5    Chen, D.6    Simon, R.P.7    Greenberg, D.A.8
  • 199
    • 79151485699 scopus 로고    scopus 로고
    • PTEN.deletion prevents ischemic brain injury by activating the mTOR signaling pathway
    • Shi, G.D.; OuYang, Y.P.; Shi, J.G.; Liu, Y.; Yuan, W.; Jia, L.S. PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway. Biochem. Biophys. Res. Commun. 2011, 404, 941-945.
    • (2011) Biochem. Biophys. Res. Commun , vol.404 , pp. 941-945
    • Shi, G.D.1    Ouyang, Y.P.2    Shi, J.G.3    Liu, Y.4    Yuan, W.5    Jia, L.S.6
  • 200
    • 65549135855 scopus 로고    scopus 로고
    • Differential expression of PTEN in normal adult rat brain and upregulation of PTEN and p-Akt in the ischemic cerebral cortex
    • Cai, Q.Y.; Chen, X.S.; Zhong, S.C.; Luo, X.; Yao, Z.X. Differential expression of PTEN in normal adult rat brain and upregulation of PTEN and p-Akt in the ischemic cerebral cortex. Anat. Rec. (Hoboken) 2009, 292, 498-512.
    • (2009) Anat. Rec. (Hoboken) , vol.292 , pp. 498-512
    • Cai, Q.Y.1    Chen, X.S.2    Zhong, S.C.3    Luo, X.4    Yao, Z.X.5
  • 202
    • 33747033469 scopus 로고    scopus 로고
    • Neuroprotection and thrombolysis: Combination therapy in acute ischaemic stroke
    • Ly, J.V.; Zavala, J.A.; Donnan, G.A. Neuroprotection and thrombolysis: Combination therapy in acute ischaemic stroke. Expert Opin. Pharmaco. 2006, 7, 1571-1581.
    • (2006) Expert Opin. Pharmaco , vol.7 , pp. 1571-1581
    • Ly, J.V.1    Zavala, J.A.2    Donnan, G.A.3
  • 203
    • 0027216836 scopus 로고
    • Attenuation of excitatory amino-acid toxicity by metabotropic glutamate-receptor agonists and aniracetam in primary cultures of cerebellar granule cells
    • Pizzi, M.; Fallacara, C.; Arrighi, V.; Memo, M.; Spano, P. Attenuation of excitatory amino-acid toxicity by metabotropic glutamate-receptor agonists and aniracetam in primary cultures of cerebellar granule cells. J. Neurochem. 1993, 61, 683-689.
    • (1993) J. Neurochem , vol.61 , pp. 683-689
    • Pizzi, M.1    Fallacara, C.2    Arrighi, V.3    Memo, M.4    Spano, P.5
  • 206
    • 0031770414 scopus 로고    scopus 로고
    • Mechanisms of neuronal damage in brain hypoxia/ischemia: Focus on the role of mitochondrial calcium accumulation
    • Budd, S.L. Mechanisms of neuronal damage in brain hypoxia/ischemia: Focus on the role of mitochondrial calcium accumulation. Pharmacol. Ther. 1998, 80, 203-229.
    • (1998) Pharmacol. Ther , vol.80 , pp. 203-229
    • Budd, S.L.1
  • 207
    • 78650035858 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of excitotoxic neuronal death
    • Wang, Y.; Qin, Z.H. Molecular and cellular mechanisms of excitotoxic neuronal death. Apoptosis 2010, 15, 1382-1402.
    • (2010) Apoptosis , vol.15 , pp. 1382-1402
    • Wang, Y.1    Qin, Z.H.2
  • 208
    • 0032509776 scopus 로고    scopus 로고
    • Direct evidence for the role of nitric oxide on the glutamate-induced neuronal death in cultured cortical neurons
    • Yamauchi, M.; Omote, K.; Ninomiya, T. Direct evidence for the role of nitric oxide on the glutamate-induced neuronal death in cultured cortical neurons. Brain Res. 1998, 780, 253-259.
    • (1998) Brain Res , vol.780 , pp. 253-259
    • Yamauchi, M.1    Omote, K.2    Ninomiya, T.3
  • 209
    • 0025674468 scopus 로고
    • N-methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic-acid release in primary cultures of cerebellar granule cells
    • Lazarewicz, J.W.; Wroblewski, J.T.; Costa, E. N-methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic-acid release in primary cultures of cerebellar granule cells. J. Neurochem. 1990, 55, 1875-1881.
    • (1990) J. Neurochem , vol.55 , pp. 1875-1881
    • Lazarewicz, J.W.1    Wroblewski, J.T.2    Costa, E.3
  • 210
    • 0028841482 scopus 로고
    • Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage
    • Kokaia, Z.; Zhao, Q.; Kokaia, M.; Elmer, E.; Metsis, M.; Smith, M.L.; Siesjo, B.K.; Lindvall, O. Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage. Exp. Neurol. 1995, 136, 73-88.
    • (1995) Exp. Neurol , vol.136 , pp. 73-88
    • Kokaia, Z.1    Zhao, Q.2    Kokaia, M.3    Elmer, E.4    Metsis, M.5    Smith, M.L.6    Siesjo, B.K.7    Lindvall, O.8
  • 211
    • 73749088302 scopus 로고    scopus 로고
    • Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression
    • Kawashima, H.; Numakawa, T.; Kumamaru, E.; Adachi, N.; Mizuno, H.; Ninomiya, M.; Kunugi, H.; Hashido, K. Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression. Neuroscience 2010, 165, 1301-1311.
    • (2010) Neuroscience , vol.165 , pp. 1301-1311
    • Kawashima, H.1    Numakawa, T.2    Kumamaru, E.3    Adachi, N.4    Mizuno, H.5    Ninomiya, M.6    Kunugi, H.7    Hashido, K.8
  • 213
    • 84860220679 scopus 로고    scopus 로고
    • Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway
    • Efthimiadi, L.; Farso, M.; Quirion, R.; Krantic, S. Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway. Neurodegener. Dis. 2012, 10, 80-91.
    • (2012) Neurodegener. Dis , vol.10 , pp. 80-91
    • Efthimiadi, L.1    Farso, M.2    Quirion, R.3    Krantic, S.4
  • 214
    • 78149275209 scopus 로고    scopus 로고
    • Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke
    • Hayakawa, K.; Qiu, J.H.; Lo, E.H. Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke. Ann. N. Y. Acad. Sci. 2010, 1207, 50-57.
    • (2010) Ann. N. Y. Acad. Sci , vol.1207 , pp. 50-57
    • Hayakawa, K.1    Qiu, J.H.2    Lo, E.H.3
  • 215
    • 33847644971 scopus 로고    scopus 로고
    • The inflammatory response in stroke
    • Wang, Q.; Tang, X.N.; Yenari, M.A. The inflammatory response in stroke. J. Neuroimmunol. 2007, 184, 53-68.
    • (2007) J. Neuroimmunol , vol.184 , pp. 53-68
    • Wang, Q.1    Tang, X.N.2    Yenari, M.A.3
  • 216
    • 77957088682 scopus 로고    scopus 로고
    • Microglial activation in stroke: Therapeutic targets
    • Yenari, M.A.; Kauppinen, T.M.; Swanson, R.A. Microglial activation in stroke: Therapeutic targets. Neurotherapeutics 2010, 7, 378-391.
    • (2010) Neurotherapeutics , vol.7 , pp. 378-391
    • Yenari, M.A.1    Kauppinen, T.M.2    Swanson, R.A.3
  • 217
    • 34447559410 scopus 로고    scopus 로고
    • Involvement of IL-1 beta in acute stress-induced worsening of cerebral ischaemia in rats
    • Caso, J.R.; Moro, M.A.; Lorenzo, P.; Lizasoain, I.; Leza, J.C. Involvement of IL-1 beta in acute stress-induced worsening of cerebral ischaemia in rats. Eur. Neuropsychopharm. 2007, 17, 600-607.
    • (2007) Eur. Neuropsychopharm , vol.17 , pp. 600-607
    • Caso, J.R.1    Moro, M.A.2    Lorenzo, P.3    Lizasoain, I.4    Leza, J.C.5
  • 220
    • 53549132254 scopus 로고    scopus 로고
    • Cell adhesion molecules and ischemic stroke
    • Yilmaz, G.; Granger, D.N. Cell adhesion molecules and ischemic stroke. Neurol. Res. 2008, 30, 783-793.
    • (2008) Neurol. Res , vol.30 , pp. 783-793
    • Yilmaz, G.1    Granger, D.N.2
  • 222
    • 77952547253 scopus 로고    scopus 로고
    • Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator
    • Jin, R.; Yang, G.J.; Li, G.H. Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator. Neurobiol. Dis. 2010, 38, 376-385.
    • (2010) Neurobiol. Dis , vol.38 , pp. 376-385
    • Jin, R.1    Yang, G.J.2    Li, G.H.3
  • 223
    • 79952994992 scopus 로고    scopus 로고
    • miR-124a as a key regulator of proliferation and MCP-1 secretion in synoviocytes from patients with rheumatoid arthritis
    • Kawano, S.; Nakamachi, Y. miR-124a as a key regulator of proliferation and MCP-1 secretion in synoviocytes from patients with rheumatoid arthritis. Ann. Rheum. Dis. 2011, 70, I88-I91.
    • (2011) Ann. Rheum. Dis , vol.70
    • Kawano, S.1    Nakamachi, Y.2
  • 225
    • 77449152992 scopus 로고    scopus 로고
    • Oxidative stress and its role in the pathogenesis of ischaemic stroke
    • Allen, C.L.; Bayraktutan, U. Oxidative stress and its role in the pathogenesis of ischaemic stroke. Int. J. Stroke 2009, 4, 461-470.
    • (2009) Int. J. Stroke , vol.4 , pp. 461-470
    • Allen, C.L.1    Bayraktutan, U.2
  • 226
    • 34548280355 scopus 로고    scopus 로고
    • Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke
    • Saeed, S.A.; Shad, K.F.; Saleem, T.; Javed, F.; Khan, M.U. Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke. Exp. Brain Res. 2007, 182, 1-10.
    • (2007) Exp. Brain Res , vol.182 , pp. 1-10
    • Saeed, S.A.1    Shad, K.F.2    Saleem, T.3    Javed, F.4    Khan, M.U.5
  • 230
    • 84867632633 scopus 로고    scopus 로고
    • MiR-21 represses FasL in microglia and protects against microglia-mediated neuronal cell death following hypoxia/ischemia
    • Zhang, L.; Dong, L.Y.; Li, Y.J.; Hong, Z.; Wei, W.S. MiR-21 represses FasL in microglia and protects against microglia-mediated neuronal cell death following hypoxia/ischemia. Glia 2012, 60, 1888-1895.
    • (2012) Glia , vol.60 , pp. 1888-1895
    • Zhang, L.1    Dong, L.Y.2    Li, Y.J.3    Hong, Z.4    Wei, W.S.5
  • 231
    • 81955161912 scopus 로고    scopus 로고
    • miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo
    • Ouyang, Y.B.; Lu, Y.; Yue, S.; Xu, L.J.; Xiong, X.X.; White, R.E.; Sun, X.; Giffard, R.G. miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo. Neurobiol. Dis. 2012, 45, 555-563.
    • (2012) Neurobiol. Dis , vol.45 , pp. 555-563
    • Ouyang, Y.B.1    Lu, Y.2    Yue, S.3    Xu, L.J.4    Xiong, X.X.5    White, R.E.6    Sun, X.7    Giffard, R.G.8
  • 232
    • 84857683479 scopus 로고    scopus 로고
    • An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model
    • Selvamani, A.; Sathyan, P.; Miranda, R.C.; Sohrabji, F. An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model. PLoS One 2012, 7, e32662.
    • (2012) PLoS One , vol.e32662 , pp. 7
    • Selvamani, A.1    Sathyan, P.2    Miranda, R.C.3    Sohrabji, F.4
  • 233
    • 15744387853 scopus 로고    scopus 로고
    • The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina
    • Young, T.L.; Matsuda, T.; Cepko, C.L. The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Curr. Biol. 2005, 15, 501-512.
    • (2005) Curr. Biol , vol.15 , pp. 501-512
    • Young, T.L.1    Matsuda, T.2    Cepko, C.L.3
  • 234
    • 84863489478 scopus 로고    scopus 로고
    • Involvement of long noncoding RNAs in diseases affecting the central nervous system
    • Pastori, C.; Wahlestedt, C. Involvement of long noncoding RNAs in diseases affecting the central nervous system. RNA Biol. 2012, 9, 860-870.
    • (2012) RNA Biol , vol.9 , pp. 860-870
    • Pastori, C.1    Wahlestedt, C.2
  • 235
    • 79953858598 scopus 로고    scopus 로고
    • Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
    • Alvarez-Erviti, L.; Seow, Y.; Yin, H.; Betts, C.; Lakhal, S.; Wood, M.J. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat. Biotechnol. 2011, 29, 341-345.
    • (2011) Nat. Biotechnol , vol.29 , pp. 341-345
    • Alvarez-Erviti, L.1    Seow, Y.2    Yin, H.3    Betts, C.4    Lakhal, S.5    Wood, M.J.6
  • 236
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R.C.; Feinbaum, R.L.; Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75, 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 237
    • 34247589595 scopus 로고    scopus 로고
    • Control of stress-dependent cardiac growth and gene expression by a microRNA
    • Van Rooij, E.; Sutherland, L.B.; Qi, X.; Richardson, J.A.; Hill, J.; Olson, E.N. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 2007, 316, 575-579.
    • (2007) Science , vol.316 , pp. 575-579
    • van Rooij, E.1    Sutherland, L.B.2    Qi, X.3    Richardson, J.A.4    Hill, J.5    Olson, E.N.6
  • 240
    • 0033811469 scopus 로고    scopus 로고
    • Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates bax and bcl-2 expression after temporary focal cerebral ischemia
    • Schabitz, W.R.; Sommer, C.; Zoder, W.; Kiessling, M.; Schwaninger, M.; Schwab, S. Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates bax and bcl-2 expression after temporary focal cerebral ischemia. Stroke 2000, 31, 2212-2217.
    • (2000) Stroke , vol.31 , pp. 2212-2217
    • Schabitz, W.R.1    Sommer, C.2    Zoder, W.3    Kiessling, M.4    Schwaninger, M.5    Schwab, S.6
  • 241
    • 0035109207 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat
    • Ferrer, I.; Krupinski, J.; Goutan, E.; Marti, E.; Ambrosio, S.; Arenas, E. Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat. Acta Neuropathol. 2001, 101, 229-238.
    • (2001) Acta Neuropathol , vol.101 , pp. 229-238
    • Ferrer, I.1    Krupinski, J.2    Goutan, E.3    Marti, E.4    Ambrosio, S.5    Arenas, E.6
  • 242
    • 12344336804 scopus 로고    scopus 로고
    • Neuroprotection in experimental stroke with targeted neurotrophins
    • Wu, D. Neuroprotection in experimental stroke with targeted neurotrophins. NeuroRx 2005, 2, 120-128.
    • (2005) NeuroRx , vol.2 , pp. 120-128
    • Wu, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.