-
1
-
-
0028817786
-
Primary prevention of stroke
-
Bronner, L. L., Kanter, D. S., and Manson, J. E. 1995. Primary prevention of stroke. N. Engl. J. Med. 333:1392-1400.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1392-1400
-
-
Bronner, L.L.1
Kanter, D.S.2
Manson, J.E.3
-
2
-
-
0034618861
-
Treatment of acute ischemic stroke
-
Brott, T. and Bogousslavsky, J. 2000. Treatment of acute ischemic stroke. N. Engl. J. Med. 343:710-722.
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 710-722
-
-
Brott, T.1
Bogousslavsky, J.2
-
3
-
-
0030609883
-
Altered gene expression in brain ischemia
-
Koistinaho, J. and Hökfelt, T. 1997. Altered gene expression in brain ischemia. Neuroreport 8:i-viii.
-
(1997)
Neuroreport
, vol.8
, pp. i-viii
-
-
Koistinaho, J.1
Hökfelt, T.2
-
4
-
-
0028798574
-
bcl-2 is expressed in neurons that survive focal ischemia in the rat
-
Chen, J., Graham, S. H., Chan, P. H., Lan, J., Zhou, R. L., and Simon, R. P. 1995. bcl-2 is expressed in neurons that survive focal ischemia in the rat. Neuroreport 6:394-398.
-
(1995)
Neuroreport
, vol.6
, pp. 394-398
-
-
Chen, J.1
Graham, S.H.2
Chan, P.H.3
Lan, J.4
Zhou, R.L.5
Simon, R.P.6
-
5
-
-
0029884441
-
Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia
-
Chen, J., Zhu, R. L., Nakayama, M., Kawaguchi, K., Jin, K., Stetler, R. A., Simon, R. P., and Graham, S. H. 1996. Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia. J. Neurochem. 67:64-71.
-
(1996)
J. Neurochem.
, vol.67
, pp. 64-71
-
-
Chen, J.1
Zhu, R.L.2
Nakayama, M.3
Kawaguchi, K.4
Jin, K.5
Stetler, R.A.6
Simon, R.P.7
Graham, S.H.8
-
6
-
-
0032124903
-
Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
-
Chen, J., Nagayama, T., Jin, K., Stetler, R. A., Zhu, R. L., Graham, S. H., and Simon, R. P. 1998. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci. 18:4914-4928.
-
(1998)
J. Neurosci.
, vol.18
, pp. 4914-4928
-
-
Chen, J.1
Nagayama, T.2
Jin, K.3
Stetler, R.A.4
Zhu, R.L.5
Graham, S.H.6
Simon, R.P.7
-
7
-
-
0035122040
-
Programmed cell death in cerebral ischemia
-
Graham, S. H. and Chen, J. 2001. Programmed cell death in cerebral ischemia. J. Cereb. Blood Flow Metab. 21:99-109.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 99-109
-
-
Graham, S.H.1
Chen, J.2
-
8
-
-
0033932195
-
Multiple molecular penumbras after focal cerebral ischemia
-
Sharp, F. R., Lu, A., Tang, Y., and Millhorn, D. E. 2000. Multiple molecular penumbras after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 20:1011-1032.
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 1011-1032
-
-
Sharp, F.R.1
Lu, A.2
Tang, Y.3
Millhorn, D.E.4
-
9
-
-
0034687754
-
An alternative, nonapoptotic form of programmed cell death
-
Sperandio, S., de Belle, I., and Bredesen, D. E. 2000. An alternative, nonapoptotic form of programmed cell death. Proc. Natl. Acad. Sci. USA 97:14376-14381.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14376-14381
-
-
Sperandio, S.1
De Belle, I.2
Bredesen, D.E.3
-
10
-
-
0035845611
-
DNA microarray gene expression analysis technology and its application to neurological disorders
-
Greenberg, S. A. 2001. DNA microarray gene expression analysis technology and its application to neurological disorders. Neurology 57:755-761.
-
(2001)
Neurology
, vol.57
, pp. 755-761
-
-
Greenberg, S.A.1
-
11
-
-
84984934477
-
Expression profiling using cDNA microarrays
-
Duggan, D. J., Bittner, M., Chen, Y., Meltzer, P., and Trent, J. M. 1999. Expression profiling using cDNA microarrays. Nat. Genet. 21:10-14.
-
(1999)
Nat. Genet.
, vol.21
, pp. 10-14
-
-
Duggan, D.J.1
Bittner, M.2
Chen, Y.3
Meltzer, P.4
Trent, J.M.5
-
12
-
-
84984933234
-
High density synthetic oligonucleotide arrays
-
Lipshutz, R. J., Fodor, S. P., Gingeras, T. R., and Lockhart, D. J. 1999. High density synthetic oligonucleotide arrays. Nat. Genet. 21:20-24.
-
(1999)
Nat. Genet.
, vol.21
, pp. 20-24
-
-
Lipshutz, R.J.1
Fodor, S.P.2
Gingeras, T.R.3
Lockhart, D.J.4
-
13
-
-
0033610079
-
Gene expression profile of aging and its retardation by caloric restriction
-
Lee, C. K., Klopp, R. G., Weindruch, R., and Prolla, T. A. 1999. Gene expression profile of aging and its retardation by caloric restriction. Science 285:1390-1393.
-
(1999)
Science
, vol.285
, pp. 1390-1393
-
-
Lee, C.K.1
Klopp, R.G.2
Weindruch, R.3
Prolla, T.A.4
-
14
-
-
0030992159
-
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays
-
Heller, R. A., Schena, M., Chai, A., Shalon, D., Bedilion, T., Gilmore, J., Woolley, D. E., and Davis, R. W. 1997. Discovery and analysis of inflammatory disease-related genes using cDNA microarrays. Proc. Natl. Acad. Sci. USA 94:2150-2155.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2150-2155
-
-
Heller, R.A.1
Schena, M.2
Chai, A.3
Shalon, D.4
Bedilion, T.5
Gilmore, J.6
Woolley, D.E.7
Davis, R.W.8
-
15
-
-
0034601487
-
Genomic analysis of metastasis reveals an essential role for RhoC
-
Clark, E. A., Golub, T. R., Lander, E. S., and Hynes, R. O. 2000. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406:532-535.
-
(2000)
Nature
, vol.406
, pp. 532-535
-
-
Clark, E.A.1
Golub, T.R.2
Lander, E.S.3
Hynes, R.O.4
-
16
-
-
0034718595
-
Regional and strain-specific gene expression mapping in the adult mouse brain
-
Sandberg, R., Yasuda, R., Pankratz, D. G., Carter, T. A., Del Rio, J. A., Wodicka, L., Mayford, M., Lockhart, D. J., and Barlow, C. 2000. Regional and strain-specific gene expression mapping in the adult mouse brain. Proc. Natl. Acad. Sci. USA 97:11038-11043.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11038-11043
-
-
Sandberg, R.1
Yasuda, R.2
Pankratz, D.G.3
Carter, T.A.4
Del Rio, J.A.5
Wodicka, L.6
Mayford, M.7
Lockhart, D.J.8
Barlow, C.9
-
17
-
-
0035085455
-
Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays
-
Malaspina, A., Kaushik, N., and de Belleroche, J. 2001. Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J. Neurochem. 77:132-145.
-
(2001)
J. Neurochem.
, vol.77
, pp. 132-145
-
-
Malaspina, A.1
Kaushik, N.2
De Belleroche, J.3
-
18
-
-
0032882174
-
Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays
-
Whitney, L. W., Becker, K. G., Tresser, N. J., Caballero-Ramos, C. I., Munson, P. J., Prabhu, V. V., Trent, J. M., McFarland, H. F., and Biddison, W. E. 1999. Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays. Ann. Neurol. 46:425-428.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 425-428
-
-
Whitney, L.W.1
Becker, K.G.2
Tresser, N.J.3
Caballero-Ramos, C.I.4
Munson, P.J.5
Prabhu, V.V.6
Trent, J.M.7
McFarland, H.F.8
Biddison, W.E.9
-
19
-
-
0033933738
-
Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons
-
Ginsberg, S. D., Hemby, S. E., Lee, V. M., Eberwine, J. H., and Trojanowski, J. Q. 2000. Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Ann. Neurol. 48:77-87.
-
(2000)
Ann. Neurol.
, vol.48
, pp. 77-87
-
-
Ginsberg, S.D.1
Hemby, S.E.2
Lee, V.M.3
Eberwine, J.H.4
Trojanowski, J.Q.5
-
20
-
-
0034640357
-
Altered patterns of gene expression in response to myocardial infarction
-
Stanton, L. W., Garrard, L. J., Damm, D., Garrick, B. L., Lam, A., Kapoun, A. M., Zheng, Q., Protter, A. A., Schreiner, G. F., and White, R. T. 2000. Altered patterns of gene expression in response to myocardial infarction. Circ. Res. 86:939-945.
-
(2000)
Circ. Res.
, vol.86
, pp. 939-945
-
-
Stanton, L.W.1
Garrard, L.J.2
Damm, D.3
Garrick, B.L.4
Lam, A.5
Kapoun, A.M.6
Zheng, Q.7
Protter, A.A.8
Schreiner, G.F.9
White, R.T.10
-
21
-
-
0034712693
-
Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury
-
Sehl, P. D., Tai, J. T., Hillan, K. J., Brown, L. A., Goddard, A., Yang, R., Jin, H., and Lowe, D. G. 2000. Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury. Circulation 101: 1990-1999.
-
(2000)
Circulation
, vol.101
, pp. 1990-1999
-
-
Sehl, P.D.1
Tai, J.T.2
Hillan, K.J.3
Brown, L.A.4
Goddard, A.5
Yang, R.6
Jin, H.7
Lowe, D.G.8
-
22
-
-
0033936125
-
Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia
-
Soriano, M. A., Tessier, M., Certa, U., and Gill, R. 2000. Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. J. Cereb. Blood Flow Metab. 20:1045-1055.
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 1045-1055
-
-
Soriano, M.A.1
Tessier, M.2
Certa, U.3
Gill, R.4
-
23
-
-
0034957735
-
Microarray analysis of hippocampal gene expression in global cerebral ischemia
-
Jin, K. L., Mao, X. O., Eshoo, M. W., Nagayama, T., Minami, M., Simon, R. P., and Greenberg, D. A. 2001. Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann. Neurol. 50:93-103.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 93-103
-
-
Jin, K.L.1
Mao, X.O.2
Eshoo, M.W.3
Nagayama, T.4
Minami, M.5
Simon, R.P.6
Greenberg, D.A.7
-
24
-
-
0033981122
-
Increased expression of apoptosis-linked gene 2 (ALG2) in the rat brain after temporary focal cerebral ischemia
-
Li, W., Jin, K., Nagayama. T., He, X., Chang, J., Minami, M., Graham, S. H., Simon, R. P., and Greenberg, D. A. 2000. Increased expression of apoptosis-linked gene 2 (ALG2) in the rat brain after temporary focal cerebral ischemia. Neuroscience 96: 161-168.
-
(2000)
Neuroscience
, vol.96
, pp. 161-168
-
-
Li, W.1
Jin, K.2
Nagayama, T.3
He, X.4
Chang, J.5
Minami, M.6
Graham, S.H.7
Simon, R.P.8
Greenberg, D.A.9
-
25
-
-
0034653132
-
Expression of the RNA-binding protein TIAR is increased in neurons after ischemic cerebral injury
-
Jin, K., Li, W., Nagayama, T., He, X., Sinor, A. D., Chang, J., Mao, X., Graham, S. H., Simon, R. P., and Greenberg, D. A. 2000. Expression of the RNA-binding protein TIAR is increased in neurons after ischemic cerebral injury. J. Neurosci. Res. 59: 767-774.
-
(2000)
J. Neurosci. Res.
, vol.59
, pp. 767-774
-
-
Jin, K.1
Li, W.2
Nagayama, T.3
He, X.4
Sinor, A.D.5
Chang, J.6
Mao, X.7
Graham, S.H.8
Simon, R.P.9
Greenberg, D.A.10
-
26
-
-
0034675037
-
Induction of vascular endothelial growth factor and hypoxia-inducible factor-1α by global ischemia in rat brain
-
Jin, K. L., Mao, X. O., Goldsmith, P. C., Nagayama, T., and Greenberg, D. A. 2000. Induction of vascular endothelial growth factor and hypoxia-inducible factor-1α by global ischemia in rat brain. Neuroscience 99:577-585.
-
(2000)
Neuroscience
, vol.99
, pp. 577-585
-
-
Jin, K.L.1
Mao, X.O.2
Goldsmith, P.C.3
Nagayama, T.4
Greenberg, D.A.5
-
27
-
-
0035824824
-
Mining DNA microarray data using a novel approach based on graph theory
-
del Rio, G., Bartley, T. F., del-Rio, H., Rao, R., Jin, K. L., Greenberg, D. A., Eshoo, M., and Bredesen, D. E. 2001. Mining DNA microarray data using a novel approach based on graph theory. FEBS Lett. 509:230-234.
-
(2001)
FEBS Lett.
, vol.509
, pp. 230-234
-
-
Del Rio, G.1
Bartley, T.F.2
Del-Rio, H.3
Rao, R.4
Jin, K.L.5
Greenberg, D.A.6
Eshoo, M.7
Bredesen, D.E.8
-
28
-
-
0034086552
-
The transcription factor E2F1 modulates apoptosis of neurons
-
Hou, S. T., Callaghan, D., Fournier, M. C., Hill, I., Kang, L., Massie, B., Morley, P., Murray, C., Rasquinha, I., Slack, R., and MacManus, J. P. 2000. The transcription factor E2F1 modulates apoptosis of neurons. J. Neurochem. 75:91-100.
-
(2000)
J. Neurochem.
, vol.75
, pp. 91-100
-
-
Hou, S.T.1
Callaghan, D.2
Fournier, M.C.3
Hill, I.4
Kang, L.5
Massie, B.6
Morley, P.7
Murray, C.8
Rasquinha, I.9
Slack, R.10
MacManus, J.P.11
-
29
-
-
0034730122
-
Cyclin-dependent kinases as a therapeutic target for stroke
-
Osuga, H., Osuga, S., Wang, F., Fetni, R., Hogan, M. J., Slack, R. S., Hakim, A. M., Ikeda, J. E., and Park, D. S, 2000. Cyclin-dependent kinases as a therapeutic target for stroke. Proc. Natl. Acad. Sci. USA 97:10254-10259.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10254-10259
-
-
Osuga, H.1
Osuga, S.2
Wang, F.3
Fetni, R.4
Hogan, M.J.5
Slack, R.S.6
Hakim, A.M.7
Ikeda, J.E.8
Park, D.S.9
-
30
-
-
0033538996
-
Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1
-
MacManus, J. P., Koch, C. J., Jian, M., Walker, T., and Zurakowski, B. 1999. Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1. Neuroreport 10:2711-2714.
-
(1999)
Neuroreport
, vol.10
, pp. 2711-2714
-
-
MacManus, J.P.1
Koch, C.J.2
Jian, M.3
Walker, T.4
Zurakowski, B.5
-
31
-
-
0035205029
-
Blood genomic responses differ following stroke, seizures, hypoglycemia and hypoxia: Blood genomic fingerprints of disease
-
Tang, Y., Lu, A., Aronow, B. J., and Sharp, F. R. 2001. Blood genomic responses differ following stroke, seizures, hypoglycemia and hypoxia: Blood genomic fingerprints of disease. Ann. Neurol. 50:699-707.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 699-707
-
-
Tang, Y.1
Lu, A.2
Aronow, B.J.3
Sharp, F.R.4
-
32
-
-
0028205768
-
Pre- and postsynaptic modulators of excitatory neurotransmission: Comparative effects on hypoxia/hypoglycemia in cortical cultures
-
Koretz, B., Ahern, K. v. B., Lustig, H. S., and Greenberg, D. A. 1994. Pre- and postsynaptic modulators of excitatory neurotransmission: Comparative effects on hypoxia/hypoglycemia in cortical cultures. Brain Res. 643:334-337.
-
(1994)
Brain Res.
, vol.643
, pp. 334-337
-
-
Koretz, B.1
Ahern, K.V.B.2
Lustig, H.S.3
Greenberg, D.A.4
-
33
-
-
0000481740
-
Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
-
Jin, K. L., Mao, X. O., and Greenberg, D. A. 2000. Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia. Proc. Natl. Acad. Sci. USA 97:10242-10247.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10242-10247
-
-
Jin, K.L.1
Mao, X.O.2
Greenberg, D.A.3
-
34
-
-
0035909992
-
Neuroglobin is upregulated by and protects neurons from hypoxic-ischemic injury
-
Sun, Y., Jin, K., Mao, X. O., Zhu, Y., and Greenberg, D. A. 2001. Neuroglobin is upregulated by and protects neurons from hypoxic-ischemic injury. Proc. Natl. Acad. Sci. USA 98:15306-15311.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15306-15311
-
-
Sun, Y.1
Jin, K.2
Mao, X.O.3
Zhu, Y.4
Greenberg, D.A.5
-
35
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, P. and Sacchi, N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
36
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri, K. F. and Kroemer, G. 2001. Organelle-specific initiation of cell death pathways. Nat. Cell Biol. 3:E255-E263.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. E255-E263
-
-
Ferri, K.F.1
Kroemer, G.2
-
37
-
-
0035190132
-
Endoplasmic reticulum dysfunction - A common denominator for cell injury in acute and degenerative diseases of the brain?
-
Paschen, W. and Frandsen, A. 2001. Endoplasmic reticulum dysfunction - A common denominator for cell injury in acute and degenerative diseases of the brain? J. Neurochem. 79:719-725.
-
(2001)
J. Neurochem.
, vol.79
, pp. 719-725
-
-
Paschen, W.1
Frandsen, A.2
-
38
-
-
0035966320
-
The unfolding tale of the unfolded protein response
-
Ma, Y. and Hendershot, L. M. 2001. The unfolding tale of the unfolded protein response. Cell 107:827-830.
-
(2001)
Cell
, vol.107
, pp. 827-830
-
-
Ma, Y.1
Hendershot, L.M.2
-
39
-
-
0034681340
-
ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum
-
Cabibbo, A., Pagani, M., Fabbri, M., Rocchi, M., Farmery, M. R., Bulleid, N. J., and Sitia, R. 2000. ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum. J. Biol. Chem. 275:4827-4833.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4827-4833
-
-
Cabibbo, A.1
Pagani, M.2
Fabbri, M.3
Rocchi, M.4
Farmery, M.R.5
Bulleid, N.J.6
Sitia, R.7
-
40
-
-
0034602319
-
Functional characterization of a mammalian Sac 1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity
-
Nemoto, Y., Kearns, B. G., Wenk, M. R., Chen, H., Mori, K., Alb, J. G., Jr., De Camilli, P., and Bankaitis, V. A. 2000. Functional characterization of a mammalian Sac 1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity. J. Biol. Chem. 275:34293-34305.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34293-34305
-
-
Nemoto, Y.1
Kearns, B.G.2
Wenk, M.R.3
Chen, H.4
Mori, K.5
Alb, J.G.6
De Camilli, P.7
Bankaitis, V.A.8
-
41
-
-
0025845887
-
Brain polyphosphoinositide metabolism during focal ischemia in rat cortex
-
Lin, T. N., Liu, T. H., Xu, J., Hsu, C. Y., and Sun, G. Y. 1991. Brain polyphosphoinositide metabolism during focal ischemia in rat cortex. Stroke 22:495-498.
-
(1991)
Stroke
, vol.22
, pp. 495-498
-
-
Lin, T.N.1
Liu, T.H.2
Xu, J.3
Hsu, C.Y.4
Sun, G.Y.5
-
42
-
-
0026546365
-
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
-
Ron, D. and Habener, J. F. 1992. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 6:439-453.
-
(1992)
Genes Dev.
, vol.6
, pp. 439-453
-
-
Ron, D.1
Habener, J.F.2
-
43
-
-
0034712939
-
Hypoxia-inducible factor lalpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
-
Sutter, C. H., Laughner, E., and Semenza, G. L. 2000. Hypoxia-inducible factor lalpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc. Natl. Acad. Sci. USA 97:4748-4753.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4748-4753
-
-
Sutter, C.H.1
Laughner, E.2
Semenza, G.L.3
-
44
-
-
0035377241
-
Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7
-
Ardley, H. C., Tan, N. G., Rose, S. A., Markham, A. F., and Robinson, P. A. 2001. Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7. J. Biol. Chem. 276:19640-19647.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19640-19647
-
-
Ardley, H.C.1
Tan, N.G.2
Rose, S.A.3
Markham, A.F.4
Robinson, P.A.5
-
45
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
46
-
-
0035834598
-
Identification of genes differentially induced by hypoxia in pancreatic cancer cells
-
Yoon, D. Y., Buchler, P., Saarikoski, S. T., Hines, O. J., Reber, H. A., and Hankinson, O. 2001. Identification of genes differentially induced by hypoxia in pancreatic cancer cells. Biochem. Biophys. Res. Commun. 288:882-886.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 882-886
-
-
Yoon, D.Y.1
Buchler, P.2
Saarikoski, S.T.3
Hines, O.J.4
Reber, H.A.5
Hankinson, O.6
-
47
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza, G. L., Jiang, B. H., Leung, S. W., Passantino, R., Concordet, J. P., Maire, P., and Giallongo, A. 1996. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J. Biol. Chem. 271:32529-32537.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
Giallongo, A.7
-
48
-
-
0027981954
-
Alterations of annexin expression in pathological neuronal and glial reactions. Immunohistochemical localization of annexins I, II (p36 and p11 subunits), IV, and VI in the human hippocampus
-
Eberhard, D. A., Brown, M. D., and VandenBerg, S. R. 1994. Alterations of annexin expression in pathological neuronal and glial reactions. Immunohistochemical localization of annexins I, II (p36 and p11 subunits), IV, and VI in the human hippocampus. Am. J. Pathol. 145:640-649.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 640-649
-
-
Eberhard, D.A.1
Brown, M.D.2
VandenBerg, S.R.3
-
49
-
-
0026758356
-
The growth arrest-specific gene, gas1, is involved in growth suppression
-
Del Sal, G., Ruaro, M. E., Philipson, L., and Schneider, C. 1992. The growth arrest-specific gene, gas1, is involved in growth suppression. Cell 70:595-607.
-
(1992)
Cell
, vol.70
, pp. 595-607
-
-
Del Sal, G.1
Ruaro, M.E.2
Philipson, L.3
Schneider, C.4
-
50
-
-
0035894884
-
Experience-dependent plasticity of mouse visual cortex in the absence of the neuronal activity-dependent marker egr1/ zif268
-
Mataga, N., Fujishima, S., Condie, B. G., and Hensch, T. K. 2001. Experience-dependent plasticity of mouse visual cortex in the absence of the neuronal activity-dependent marker egr1/ zif268. J. Neurosci. 21:9724-9732.
-
(2001)
J. Neurosci.
, vol.21
, pp. 9724-9732
-
-
Mataga, N.1
Fujishima, S.2
Condie, B.G.3
Hensch, T.K.4
-
51
-
-
0033910767
-
N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom
-
Kalaydjieva, L., Gresham, D., Gooding, R., Heather, L., Baas, F., de Jonge, R., Blechschmidt, K., Angelicheva, D., Chandler, D., Worsley, P., Rosenthal, A., King, R. H., and Thomas, P. K. 2000. N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom. Am. J. Genet. 67:47-58.
-
(2000)
Am. J. Genet.
, vol.67
, pp. 47-58
-
-
Kalaydjieva, L.1
Gresham, D.2
Gooding, R.3
Heather, L.4
Baas, F.5
De Jonge, R.6
Blechschmidt, K.7
Angelicheva, D.8
Chandler, D.9
Worsley, P.10
Rosenthal, A.11
King, R.H.12
Thomas, P.K.13
-
52
-
-
0033519705
-
Bc1-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
Shimizu, S., Narita, M., and Tsujimoto, Y. 1999. Bc1-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399:483-487.
-
(1999)
Nature
, vol.399
, pp. 483-487
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
53
-
-
0034104098
-
Mitochondrial porin required for ischemia-induced mitochondrial dysfunction and neuronal damage
-
Perez Velazquez, J. L., Frantseva, M. V., Huzar, D. V., and Carlen, P. L. 2000. Mitochondrial porin required for ischemia-induced mitochondrial dysfunction and neuronal damage. Neuroscience 97:363-369.
-
(2000)
Neuroscience
, vol.97
, pp. 363-369
-
-
Perez Velazquez, J.L.1
Frantseva, M.V.2
Huzar, D.V.3
Carlen, P.L.4
-
54
-
-
0033537975
-
NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway
-
Lu, Y., Brush, J., and Stewart, T. A. 1999. NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway. J. Biol. Chem. 274:10047-10052.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10047-10052
-
-
Lu, Y.1
Brush, J.2
Stewart, T.A.3
-
55
-
-
0034724978
-
c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion
-
Hayashi, T., Sakai, K., Sasaki, C., Zhang, W. R., Warita, H., and Abe, K. 2000. c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion. Neurosci. Lett. 284:195-199.
-
(2000)
Neurosci. Lett.
, vol.284
, pp. 195-199
-
-
Hayashi, T.1
Sakai, K.2
Sasaki, C.3
Zhang, W.R.4
Warita, H.5
Abe, K.6
-
56
-
-
0035853720
-
Molecular cloning and characterization of a zinc finger protein involved in Id-1-stimulated mammary epithelial cell growth
-
Singh, J., Itahana, Y., Parrinello, S., Murata, K., and Desprez, P. Y. 2001. Molecular cloning and characterization of a zinc finger protein involved in Id-1-stimulated mammary epithelial cell growth. J. Biol. Chem. 276:11852-11858.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11852-11858
-
-
Singh, J.1
Itahana, Y.2
Parrinello, S.3
Murata, K.4
Desprez, P.Y.5
-
57
-
-
0032079716
-
The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120
-
Ren, Y., Busch, R. K., Perlaky, L., and Busch, H. 1998. The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120. Eur. J. Biochem. 253:734-742.
-
(1998)
Eur. J. Biochem.
, vol.253
, pp. 734-742
-
-
Ren, Y.1
Busch, R.K.2
Perlaky, L.3
Busch, H.4
-
58
-
-
0031591673
-
Abnormalities of sensory and memory functions in mice lacking Bsg gene
-
Naruhashi, K., Kadomatsu, K., Igakura, T., Fan, Q. W., Kuno, N., Muramatsu, H., Miyauchi, T., Hasegawa, T., Itoh, A., Muramatsu, T., and Nabeshima, T. 1997. Abnormalities of sensory and memory functions in mice lacking Bsg gene. Biochem. Biophys. Res. Commun. 236:733-737.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 733-737
-
-
Naruhashi, K.1
Kadomatsu, K.2
Igakura, T.3
Fan, Q.W.4
Kuno, N.5
Muramatsu, H.6
Miyauchi, T.7
Hasegawa, T.8
Itoh, A.9
Muramatsu, T.10
Nabeshima, T.11
-
59
-
-
0034923656
-
Fatty acid-binding proteins of nervous tissue
-
Veerkamp, J. H. and Zimmerman, A. W. 2001. Fatty acid-binding proteins of nervous tissue. J. Mol. Neurosci. 16:133-142.
-
(2001)
J. Mol. Neurosci.
, vol.16
, pp. 133-142
-
-
Veerkamp, J.H.1
Zimmerman, A.W.2
-
60
-
-
0035861882
-
In vitro clonal analysis of rat cerebral cortical neurons expressing latexin, a subtype-specific molecular marker of glutamatergic neurons
-
Takiguchi-Hayashi, K. 2001. In vitro clonal analysis of rat cerebral cortical neurons expressing latexin, a subtype-specific molecular marker of glutamatergic neurons. Dev. Brain Res. 132: 87-90.
-
(2001)
Dev. Brain Res.
, vol.132
, pp. 87-90
-
-
Takiguchi-Hayashi, K.1
-
62
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A., and Yuan, J. 2000. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403:98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
63
-
-
0035823579
-
Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
-
Rao, R. V., Hermel, E., Castro-Obregon, S., del Rio, G., Ellerby, L. M., Ellerby, H. M., and Bredesen, D. E. 2001. Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J. Biol. Chem. 276:33869-33874.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33869-33874
-
-
Rao, R.V.1
Hermel, E.2
Castro-Obregon, S.3
Del Rio, G.4
Ellerby, L.M.5
Ellerby, H.M.6
Bredesen, D.E.7
-
64
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough, K. D., Martindale, J. L., Klotz, L. O., Aw, T.Y., and Holbrook, N. J. 2001. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol. Cell Biol. 21:1249-1259.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
65
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza, G. L. HIF-1 and mechanisms of hypoxia sensing. Curr. Opin. Cell Biol. 13:167-171.
-
Curr. Opin. Cell Biol.
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
66
-
-
0035917313
-
2 sensing
-
2 sensing. Science 292:464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin, W.G.10
-
67
-
-
0034744522
-
Cellular mechanisms of oxygen sensing
-
Lopez-Barneo, J., Pardal, R., and Ortega-Saenz, P. 2001. Cellular mechanisms of oxygen sensing. Annu. Rev. Physiol. 63:259-287.
-
(2001)
Annu. Rev. Physiol.
, vol.63
, pp. 259-287
-
-
Lopez-Barneo, J.1
Pardal, R.2
Ortega-Saenz, P.3
-
68
-
-
0000655498
-
Identification of a hypoxia response element in the transferrin receptor gene
-
Lok, C. N. and Ponka, P. 1999. Identification of a hypoxia response element in the transferrin receptor gene. J. Biol. Chem. 274:24147-24152.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24147-24152
-
-
Lok, C.N.1
Ponka, P.2
-
69
-
-
0035910429
-
Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
-
Kimura, H., Weisz, A., Ogura, T., Hitomi, Y., Kurashima, Y., Hashimoto, K., D'Acquisto, F., Makuuchi, M., and Esumi, H. 2001. Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J. Biol. Chem. 276: 2292-2298.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2292-2298
-
-
Kimura, H.1
Weisz, A.2
Ogura, T.3
Hitomi, Y.4
Kurashima, Y.5
Hashimoto, K.6
D'Acquisto, F.7
Makuuchi, M.8
Esumi, H.9
-
70
-
-
0034284026
-
Erythropoietin protects cultured cortical neurons, but not astroglia, from hypoxia and AMPA toxicity
-
Sinor, A. D. and Greenberg, D. A. 2000. Erythropoietin protects cultured cortical neurons, but not astroglia, from hypoxia and AMPA toxicity. Neurosci. Lett. 290:213-215.
-
(2000)
Neurosci. Lett.
, vol.290
, pp. 213-215
-
-
Sinor, A.D.1
Greenberg, D.A.2
-
71
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
Oosthuyse, B., Moons, L., Storkebaum, E., Beck, H., Nuyens, D., Brusselmans, K., Van Dorpe, J., Hellings, P., Gorselink, M., Heymans, S., Theilmeier, G., Dewerchin, M., Laudenbach, V., Vermylen, P., Raat, H., Acker, T., Vleminckx, V., Van Den Bosch, L., Cashman, N., Fujisawa, H., Drost, M. R., Sciot, R., Bruyninckx, F., Hicklin, D. J., Ince, C., Gressens, P., Lupu, F., Plate, K. H., Robberecht, W., Herbert, J.-M., Collen, D., and Carmeliet, P. 2001. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat. Genet. 28:131-138.
-
(2001)
Nat. Genet.
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
Moons, L.2
Storkebaum, E.3
Beck, H.4
Nuyens, D.5
Brusselmans, K.6
Van Dorpe, J.7
Hellings, P.8
Gorselink, M.9
Heymans, S.10
Theilmeier, G.11
Dewerchin, M.12
Laudenbach, V.13
Vermylen, P.14
Raat, H.15
Acker, T.16
Vleminckx, V.17
Van Den Bosch, L.18
Cashman, N.19
Fujisawa, H.20
Drost, M.R.21
Sciot, R.22
Bruyninckx, F.23
Hicklin, D.J.24
Ince, C.25
Gressens, P.26
Lupu, F.27
Plate, K.H.28
Robberecht, W.29
Herbert, J.-M.30
Collen, D.31
Carmeliet, P.32
more..
-
72
-
-
0032588585
-
HIF-1α and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia
-
Halterman, M. W. and Federoff, H. J. 1999. HIF-1α and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia. Exp. Neurol. 159:65-72.
-
(1999)
Exp. Neurol.
, vol.159
, pp. 65-72
-
-
Halterman, M.W.1
Federoff, H.J.2
-
73
-
-
0033566792
-
Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53
-
Halterman, M. W., Miller, C. C., and Federoff, H. J. 1999. Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53. J. Neurosci. 19:6818-6824.
-
(1999)
J. Neurosci.
, vol.19
, pp. 6818-6824
-
-
Halterman, M.W.1
Miller, C.C.2
Federoff, H.J.3
-
74
-
-
0033435198
-
Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
-
Bergeron, M., Yu, A. Y., Solway, K. E., Semenza, G. L., and Sharp, F. R. 1999. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 11:4159-4170.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 4159-4170
-
-
Bergeron, M.1
Yu, A.Y.2
Solway, K.E.3
Semenza, G.L.4
Sharp, F.R.5
-
75
-
-
0033512017
-
A potential role for erythropoietin in focal permanent cerebral ischemia in mice
-
Bernaudin, M., Marti, H. H., Roussel, S., Divoux, D., Nouvelot, A., MacKenzie, E. T., and Petit, E. 1999. A potential role for erythropoietin in focal permanent cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 19:643-651.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 643-651
-
-
Bernaudin, M.1
Marti, H.H.2
Roussel, S.3
Divoux, D.4
Nouvelot, A.5
MacKenzie, E.T.6
Petit, E.7
-
76
-
-
0031683937
-
Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat
-
Lennmyr, F., Ata, K. A., Funa, K., Olsson, Y., and Terent, A. 1998. Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat. J. Neuropathol. Exp. Neurol. 57:874-882.
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 874-882
-
-
Lennmyr, F.1
Ata, K.A.2
Funa, K.3
Olsson, Y.4
Terent, A.5
-
77
-
-
0032547036
-
Vascular endothelial growth factor expression in rat focal cerebral ischemia
-
Cobbs, C. S., Chen, J., Greenberg, D. A., and Graham, S. H. 1998. Vascular endothelial growth factor expression in rat focal cerebral ischemia. Neurosci. Lett. 249:79-82.
-
(1998)
Neurosci. Lett.
, vol.249
, pp. 79-82
-
-
Cobbs, C.S.1
Chen, J.2
Greenberg, D.A.3
Graham, S.H.4
-
78
-
-
0035202803
-
Microarrays, markers of disease, and the myth of "nonhypothesis-driven" research
-
Greenberg, D. A. 2001. Microarrays, markers of disease, and the myth of "nonhypothesis-driven" research. Ann. Neurol. 50: 695.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 695
-
-
Greenberg, D.A.1
|