Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway

Neurodegenerative Diseases

Volumn 10, Issue 1-4, 2012, Pages 80-91

  Efthimiadi, L ^a   Farso, M ^b   Quirion, R ^b   Krantic, S ^a,b,c  

^a INSERM   (France)

^b DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^c CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

c Jun N terminal protein kinase pathway; Cell cycle re entry; Cyclin D1; Excitotoxicity; Extrasynaptic N methyl D aspartate receptors; Neuronal death

Indexed keywords

CYCLIN D1; JANUS KINASE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SHORT HAIRPIN RNA;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL CYCLE; CELL CYCLE S PHASE; CELL DEATH; CONTROLLED STUDY; EXCITOTOXICITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MICROGLIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTHRACENES; CELL COUNT; CELLS, CULTURED; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; KI-67 ANTIGEN; MAP KINASE SIGNALING SYSTEM; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SYNAPSES; TIME FACTORS; TRANSFECTION;

EID: 84860220679     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000335911     Document Type: Article

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