MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia

Frontiers in Bioscience - Elite

Volumn 3 E, Issue 4, 2011, Pages 1265-1272

  Zeng, Lili ^a   Liu, Jianrong ^a   Wang, Yongting ^a   Wang, Ling ^a   Weng, Suiqing ^a   Tang, Yaohui ^a   Zheng, Chaobo ^a   Cheng, Qi ^a   Chen, Shengdi ^a   Yang, Guo Yuan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Biomarker; Ischemia; MiR 210

Indexed keywords

BIOLOGICAL MARKER; MICRORNA 210; MICRORNA; MIRN210 MICRORNA, HUMAN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; BRAIN ISCHEMIA; BRAIN LEVEL; CONTROLLED STUDY; CORRELATIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NONHUMAN; OUTCOME ASSESSMENT; PROGNOSIS; QUANTITATIVE ANALYSIS; RANKIN SCALE; REAL TIME POLYMERASE CHAIN REACTION; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; STROKE PATIENT; TREATMENT OUTCOME; ACUTE DISEASE; ANIMAL; BLOOD; DISEASE MODEL; INSTITUTE FOR CANCER RESEARCH MOUSE; MIDDLE AGED; POLYMERASE CHAIN REACTION;

MUS;

ACUTE DISEASE; AGED; ANIMALS; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MICE, INBRED ICR; MICRORNAS; MIDDLE AGED; POLYMERASE CHAIN REACTION;

EID: 80053590072     PISSN: 19450494     EISSN: 19450508     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. V. Ambros: The functions of animal microRNAs. Nature 431(7006), 350-5 (2004) (Pubitemid 39265675)
2. C. Urbich, A. Kuehbacher and S. Dimmeler: Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res 79(4), 581-8 (2008)
3. S. Wang and E. N. Olson: AngiomiRs-key regulators of angiogenesis. Curr Opin Genet Dev 19(3), 205-11 (2009)
4. W. M. Pardridge: Intravenous, non-viral RNAi gene therapy of brain cancer. Expert Opin Biol Ther 4(7), 1103-13 (2004) (Pubitemid 38937552)
5. W. M. Pardridge: shRNA and siRNA delivery to the brain. Adv Drug Deliv Rev 59(2-3), 141-52 (2007) (Pubitemid 46773051)
6. D. P. Bartel: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2), 281-97 (2004)
7. R. C. Friedman, K. K. Farh, C. B. Burge and D. P. Bartel: Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19(1), 92-105 (2009)
8. X. Chen, Y. Ba, L. Ma, X. Cai, Y. Yin, K. Wang, J. Guo, Y. Zhang, J. Chen, X. Guo, Q. Li, X. Li, W. Wang, J. Wang, X. Jiang, Y. Xiang, C. Xu, P. Zheng, J. Zhang, R. Li, H. Zhang, X. Shang, T. Gong, G. Ning, K. Zen and C. Y. Zhang: Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18(10), 997-1006 (2008)
9. K. Jeyaseelan, K. Y. Lim and A. Armugam: MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion. Stroke 39(3), 959-66 (2008) (Pubitemid 351619577)
10. D. Z. Liu, Y. Tian, B. P. Ander, H. Xu, B. S. Stamova, X. Zhan, R. J. Turner, G. Jickling and F. R. Sharp: Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J Cereb Blood Flow Metab 30(1), 92-101 (2010)
11. P. Fasanaro, S. Greco, M. Ivan, M. C. Capogrossi and F. Martelli: microRNA: emerging therapeutic targets in acute ischemic diseases. Pharmacol Ther 125(1), 92-104 (2010)
12. S. Hu, M. Huang, Z. Li, F. Jia, Z. Ghosh, M. A. Lijkwan, P. Fasanaro, N. Sun, X. Wang, F. Martelli, R. C. Robbins and J. C. Wu: MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation 122(11 Suppl), S124-31 (2010)
13. C. Rink and S. Khanna: MicroRNA in Ischemic Stroke Etiology and Pathology. Physiol Genomics (2010) [Epub ahead of print]
14. K. S. Tan, A. Armugam, S. Sepramaniam, K. Y. Lim, K. D. Setyowati, C. W. Wang and K. Jeyaseelan: Expression profile of MicroRNAs in young stroke patients. PLoS One 4(11), e7689 (2009)
15. K. J. Yin, Z. Deng, H. Huang, M. Hamblin, C. Xie, J. Zhang and Y. E. Chen: miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia. Neurobiol Dis 38(1), 17-26 (2010)
16. Y. Yuan, J. Y. Wang, L. Y. Xu, R. Cai, Z. Chen and B. Y. Luo: MicroRNA expression changes in the hippocampi of rats subjected to global ischemia. J Clin Neurosci 17(6), 774-8 (2010)
17. O. F. Laterza, L. Lim, P. W. Garrett-Engele, K. Vlasakova, N. Muniappa, W. K. Tanaka, J. M. Johnson, J. F. Sina, T. L. Fare, F. D. Sistare and W. E. Glaab: Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury. Clin Chem 55(11), 1977-83 (2009)
18. A. Dharap, K. Bowen, R. Place, L. C. Li and R. Vemuganti: Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome. J Cereb Blood Flow Metab 29(4), 675-87 (2009)
19. E. R. Hutchison, E. Okun and M. P. Mattson: The therapeutic potential of microRNAs in nervous system damage, degeneration, and repair. Neuromolecular Med 11(3), 153-61 (2009)
20. M. Ivan, A. L. Harris, F. Martelli and R. Kulshreshtha: Hypoxia response and microRNAs: no longer two separate waorlds. J Cell Mol Med 12(5A), 1426-31 (2008)
21. S. Y. Chan and J. Loscalzo: MicroRNA-210: A unique and pleiotropic hypoxamir. Cell Cycle 9 (6) (2010) [Epub ahead of print]
22. S. Y. Chan, Y. Y. Zhang, C. Hemann, C. E. Mahoney, J. L. Zweier and J. Loscalzo: MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab 10(4), 273-84 (2009)
23. Z. Chen, Y. Li, H. Zhang, P. Huang and R. Luthra: Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene 29(30), 4362-8 (2010)
24. T. Kushibiki: Photodynamic therapy induces microRNA-210 and -296 expression in HeLa cells. J Biophotonics 3(5-6), 368-72 (2010)
25. E. Favaro, A. Ramachandran, R. McCormick, H. Gee, C. Blancher, M. Crosby, C. Devlin, C. Blick, F. Buffa, J. L. Li, B. Vojnovic, R. Pires Das Neves, P. Glazer, F. Iborra, M. Ivan, J. Ragoussis and A. L. Harris: MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One 5(4), e10345 (2010)
26. P. Fasanaro, Y. D'Alessandra, V. Di Stefano, R. Melchionna, S. Romani, G. Pompilio, M. C. Capogrossi and F. Martelli: MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J Biol Chem 283(23), 15878-83 (2008)
27. P. Fasanaro, S. Greco, M. Lorenzi, M. Pescatori, M. Brioschi, R. Kulshreshtha, C. Banfi, A. Stubbs, G. A. Calin, M. Ivan, M. C. Capogrossi and F. Martelli: An integrated approach for experimental target identification of hypoxiainduced miR-210. J Biol Chem 284(50), 35134-43 (2009)
28. H. W. Kim, H. K. Haider, S. Jiang and M. Ashraf: Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2. J Biol Chem 284(48), 33161-8 (2009)
29. K. Pulkkinen, T. Malm, M. Turunen, J. Koistinaho and S. Yla-Herttuala: Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210. FEBS Lett 582(16), 2397-401 (2008)
30. Y. Mao, G. Y. Yang, L. F. Zhou, J. D. Stern and A. L. Betz: Focal cerebral ischemia in the mouse: description of a model and effects of permanent and temporary occlusion. Brain Res Mol Brain Res 63(2), 366-70 (1999) (Pubitemid 29036987)
31. K. J. Livak and T. D. Schmittgen: Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) Method. Methods 25(4), 402-8 (2001) (Pubitemid 34164012)
32. K. P. Doyle, R. P. Simon and M. P. Stenzel-Poore: Mechanisms of ischemic brain damage. Neuropharmacology 55(3), 310-8 (2008)
33. R. Jin, G. Yang and G. Li: Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukoc Biol 87(5), 779-89 (2010)
34. M. Castellanos and J. Serena: Applicability of biomarkers in ischemic stroke. Cerebrovasc Dis 24 Suppl 1, 7-15 (2007) (Pubitemid 350035847)
35. C. Foerch, J. Montaner, K. L. Furie, M. M. Ning and E. H. Lo: Invited article: searching for oracles? Blood biomarkers in acute stroke. Neurology 73(5), 393-9 (2009)
36. W. Whiteley, W. L. Chong, A. Sengupta and P. Sandercock: Blood markers for the prognosis of ischemic stroke: a systematic review. Stroke 40(5), e380-9 (2009)
37. H. Xu, Y. Tang, D. Z. Liu, R. Ran, B. P. Ander, M. Apperson, X. S. Liu, J. C. Khoury, J. P. Gregg, A. Pancioli, E. C. Jauch, K. R. Wagner, P. Verro, J. P. Broderick and F. R. Sharp: Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke. J Cereb Blood Flow Metab 28(7), 1320-8 (2008) (Pubitemid 351896646)