-
1
-
-
57849140661
-
Divergent transcription from active promoters
-
PMID:19056940
-
Seila AC, Calabrese JM, Levine SS, Yeo GW, Rahl PB, Flynn RA, et al. Divergent transcription from active promoters. Science 2008; 322:1849-51; PMID:19056940; http://dx.doi.org/10.1126/science.1162253.
-
(2008)
Science
, vol.322
, pp. 1849-1851
-
-
Seila, A.C.1
Calabrese, J.M.2
Levine, S.S.3
Yeo, G.W.4
Rahl, P.B.5
Flynn, R.A.6
-
2
-
-
57849123049
-
RNA exosome depletion reveals transcription upstream of active human promoters
-
PMID:19056938
-
Preker P, Nielsen J, Kammler S, Lykke-Andersen S, Christensen MS, Mapendano CK, et al. RNA exosome depletion reveals transcription upstream of active human promoters. Science 2008; 322:1851-4; PMID:19056938; http://dx.doi.org/10.1126/science.1164096.
-
(2008)
Science
, vol.322
, pp. 1851-1854
-
-
Preker, P.1
Nielsen, J.2
Kammler, S.3
Lykke-Andersen, S.4
Christensen, M.S.5
Mapendano, C.K.6
-
3
-
-
54049138948
-
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation
-
PMID:18951091
-
Pandey RR, Mondal T, Mohammad F, Enroth S, Redrup L, Komorowski J, et al. Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell 2008; 32:232-46; PMID:18951091; http://dx.doi.org/10.1016/j.molcel.2008.08.022.
-
(2008)
Mol Cell
, vol.32
, pp. 232-246
-
-
Pandey, R.R.1
Mondal, T.2
Mohammad, F.3
Enroth, S.4
Redrup, L.5
Komorowski, J.6
-
4
-
-
56549111129
-
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin
-
PMID:18988810
-
Nagano T, Mitchell JA, Sanz LA, Pauler FM, Ferguson-Smith AC, Feil R, et al. The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science 2008; 322:1717-20; PMID:18988810; http://dx.doi.org/10. 1126/science.1163802.
-
(2008)
Science
, vol.322
, pp. 1717-1720
-
-
Nagano, T.1
Mitchell, J.A.2
Sanz, L.A.3
Pauler, F.M.4
Ferguson-Smith, A.C.5
Feil, R.6
-
5
-
-
57849105533
-
The antisense transcriptomes of human cells
-
PMID:19056939
-
He Y, Vogelstein B, Velculescu VE, Papadopoulos N, Kinzler KW. The antisense transcriptomes of human cells. Science 2008; 322:1855-7; PMID:19056939; http://dx.doi.org/10.1126/science.1163853.
-
(2008)
Science
, vol.322
, pp. 1855-1857
-
-
He, Y.1
Vogelstein, B.2
Velculescu, V.E.3
Papadopoulos, N.4
Kinzler, K.W.5
-
6
-
-
34247153327
-
Localizing hotspots of antisense transcription
-
PMID:17284453
-
Finocchiaro G, Carro MS, Francois S, Parise P, DiNinni V, Muller H. Localizing hotspots of antisense transcription. Nucleic Acids Res 2007; 35:1488-500; PMID:17284453; http://dx.doi.org/10.1093/nar/gkm027.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1488-1500
-
-
Finocchiaro, G.1
Carro, M.S.2
Francois, S.3
Parise, P.4
DiNinni, V.5
Muller, H.6
-
7
-
-
41349094797
-
Transcription regulation through promoter-proximal pausing of RNA polymerase II
-
PMID:18369138
-
Core LJ, Lis JT. Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science 2008; 319:1791-2; PMID:18369138; http://dx.doi.org/10.1126/science.1150843.
-
(2008)
Science
, vol.319
, pp. 1791-1792
-
-
Core, L.J.1
Lis, J.T.2
-
8
-
-
34250160256
-
RNA maps reveal new RNA classes and a possible function for pervasive transcription
-
PMID:17510325
-
Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, et al. RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science 2007; 316:1484-8; PMID:17510325; http://dx.doi.org/10. 1126/science.1138341.
-
(2007)
Science
, vol.316
, pp. 1484-1488
-
-
Kapranov, P.1
Cheng, J.2
Dike, S.3
Nix, D.A.4
Duttagupta, R.5
Willingham, A.T.6
-
9
-
-
36248967098
-
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals
-
PMID:17921506
-
Ladd PD, Smith LE, Rabaia NA, Moore JM, Georges SA, Hansen RS, et al. An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. Hum Mol Genet 2007; 16:3174-87; PMID:17921506; http://dx.doi.org/10.1093/hmg/ddm293.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 3174-3187
-
-
Ladd, P.D.1
Smith, L.E.2
Rabaia, N.A.3
Moore, J.M.4
Georges, S.A.5
Hansen, R.S.6
-
10
-
-
44949246486
-
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome
-
PMID:18213394
-
Khalil AM, Faghihi MA, Modarresi F, Brothers SP, Wahlestedt C. A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One 2008; 3:1486; PMID:18213394; http://dx.doi.org/10.1371/journal.pone. 0001486.
-
(2008)
PLoS One
, vol.3
, pp. 1486
-
-
Khalil, A.M.1
Faghihi, M.A.2
Modarresi, F.3
Brothers, S.P.4
Wahlestedt, C.5
-
11
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
-
PMID:19182780
-
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009; 458:223-7; PMID:19182780; http://dx.doi.org/10. 1038/nature07672.
-
(2009)
Nature
, vol.458
, pp. 223-227
-
-
Guttman, M.1
Amit, I.2
Garber, M.3
French, C.4
Lin, M.F.5
Feldser, D.6
-
12
-
-
78651325932
-
LncRNAdb: A reference database for long noncoding RNAs
-
PMID:21112873
-
Amaral PP, Clark MB, Gascoigne DK, Dinger ME, Mattick JS. lncRNAdb: a reference database for long noncoding RNAs. Nucleic Acids Res 2011; 39:146-51; PMID:21112873; http://dx.doi.org/10.1093/nar/gkq1138.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 146-151
-
-
Amaral, P.P.1
Clark, M.B.2
Gascoigne, D.K.3
Dinger, M.E.4
Mattick, J.S.5
-
13
-
-
0025721986
-
Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA
-
PMID:1657988
-
Munroe SH, Lazar MA. Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA. J BiolChem 1991; 266:22083-6; PMID:1657988.
-
(1991)
J BiolChem
, vol.266
, pp. 22083-22086
-
-
Munroe, S.H.1
Lazar, M.A.2
-
14
-
-
46749083733
-
Expression of a non-coding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase
-
PMID:18587408
-
Faghihi MA, Modarresi F, Khalil AM, Wood DE, Sahagan BG, Morgan TE, et al. Expression of a non-coding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med 2008; 14:723-30; PMID:18587408; http://dx.doi.org/10.1038/nm1784.
-
(2008)
Nat Med
, vol.14
, pp. 723-730
-
-
Faghihi, M.A.1
Modarresi, F.2
Khalil, A.M.3
Wood, D.E.4
Sahagan, B.G.5
Morgan, T.E.6
-
15
-
-
60349120914
-
Long non-coding RNAs: Insights into functions
-
PMID:19188922
-
Mercer TR, Dinger ME, Mattick JS. Long non-coding RNAs: insights into functions. Nat Rev Genet 2009; 10:155-9; PMID:19188922; http://dx.doi.org/10. 1038/nrg2521.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 155-159
-
-
Mercer, T.R.1
Dinger, M.E.2
Mattick, J.S.3
-
16
-
-
33744804277
-
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
-
PMID:16705037
-
Feng J, Bi C, Clark BS, Mady R, Shah P, Kohtz JD. The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev 2006; 20:1470-84; PMID:16705037; http://dx.doi.org/10.1101/gad.1416106.
-
(2006)
Genes Dev
, vol.20
, pp. 1470-1484
-
-
Feng, J.1
Bi, C.2
Clark, B.S.3
Mady, R.4
Shah, P.5
Kohtz, J.D.6
-
17
-
-
33846930357
-
Repression of the human dihydrofolatereductase gene by a non-coding interfering transcript
-
PMID:17237763
-
Martianov I, Ramadass A, Serra Barros A, Chow N, Akoulitchev A. Repression of the human dihydrofolatereductase gene by a non-coding interfering transcript. Nature 2007; 445:666-70; PMID:17237763; http://dx.doi.org/10.1038/ nature05519.
-
(2007)
Nature
, vol.445
, pp. 666-670
-
-
Martianov, I.1
Ramadass, A.2
Serra Barros, A.3
Chow, N.4
Akoulitchev, A.5
-
18
-
-
46649093597
-
Induced ncRNAsallosterically modify RNA-binding proteins in cis to inhibit transcription
-
PMID:18509338
-
Wang X, Arai S, Song X, Reichart D, Du K, Pascual G, et al. Induced ncRNAsallosterically modify RNA-binding proteins in cis to inhibit transcription. Nature 2008; 454:126-30; PMID:18509338; http://dx.doi.org/10. 1038/nature06992.
-
(2008)
Nature
, vol.454
, pp. 126-130
-
-
Wang, X.1
Arai, S.2
Song, X.3
Reichart, D.4
Du, K.5
Pascual, G.6
-
19
-
-
38049155825
-
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
-
PMID:18185590
-
Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008; 451:202-6; PMID:18185590; http://dx.doi.org/10.1038/nature06468.
-
(2008)
Nature
, vol.451
, pp. 202-206
-
-
Yu, W.1
Gius, D.2
Onyango, P.3
Muldoon-Jacobs, K.4
Karp, J.5
Feinberg, A.P.6
-
20
-
-
77953096072
-
Molecular interplay of the non-coding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
-
PMID:20541999
-
Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, et al. Molecular interplay of the non-coding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell 2010; 38:662-74; PMID:20541999; http://dx.doi.org/10.1016/j.molcel.2010.03.021.
-
(2010)
Mol Cell
, vol.38
, pp. 662-674
-
-
Yap, K.L.1
Li, S.2
Muñoz-Cabello, A.M.3
Raguz, S.4
Zeng, L.5
Mujtaba, S.6
-
21
-
-
57149110631
-
Bidirectional transcription directs both transcriptional gene activation and suppression in human cells
-
PMID:19008947
-
Morris KV, Santoso S, Turner AM, Pastori C, Hawkins PG. Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet 2008; 4:1000258; PMID:19008947; http://dx.doi.org/10. 1371/journal.pgen.1000258.
-
(2008)
PLoS Genet
, vol.4
, pp. 1000258
-
-
Morris, K.V.1
Santoso, S.2
Turner, A.M.3
Pastori, C.4
Hawkins, P.G.5
-
22
-
-
67650921949
-
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
-
PMID:19571010
-
Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, et al. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci USA 2009; 106:11667-72; PMID:19571010; http://dx.doi.org/10.1073/pnas.0904715106.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11667-11672
-
-
Khalil, A.M.1
Guttman, M.2
Huarte, M.3
Garber, M.4
Raj, A.5
Rivea Morales, D.6
-
23
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
PMID:17604720
-
Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 2007; 129:1311-23; PMID:17604720; http://dx.doi.org/10. 1016/j.cell.2007.05.022.
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
Squazzo, S.L.4
Xu, X.5
Brugmann, S.A.6
-
24
-
-
79955622702
-
Epigenetic regulation of gene expression in physiological and pathological brain processes
-
PMID:21527733
-
Gräff J, Kim D, Dobbin MM, Tsai LH. Epigenetic regulation of gene expression in physiological and pathological brain processes. Physiol Rev 2011; 91:603-49; PMID:21527733; http://dx.doi.org/10.1152/physrev.00012.2010.
-
(2011)
Physiol Rev
, vol.91
, pp. 603-649
-
-
Gräff, J.1
Kim, D.2
Dobbin, M.M.3
Tsai, L.H.4
-
25
-
-
52449130135
-
Noncoding RNAs in Long-Term Memory Formation
-
PMID:18997122
-
Mercer TR, Dinger ME, Mariani J, Kosik KS, Mehler MF, Mattick JS. Noncoding RNAs in Long-Term Memory Formation. Neuroscientist 2008; 14:434-45; PMID:18997122; http://dx.doi.org/10.1177/1073858408319187.
-
(2008)
Neuroscientist
, vol.14
, pp. 434-445
-
-
Mercer, T.R.1
Dinger, M.E.2
Mariani, J.3
Kosik, K.S.4
Mehler, M.F.5
Mattick, J.S.6
-
26
-
-
77956882723
-
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression
-
PMID:20729808
-
Bernard D, Prasanth KV, Tripathi V, Colasse S, Nakamura T, Xuan Z, et al. A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO J 2010; 29:3082-93; PMID:20729808; http://dx.doi.org/10. 1038/emboj.2010.199.
-
(2010)
EMBO J
, vol.29
, pp. 3082-3093
-
-
Bernard, D.1
Prasanth, K.V.2
Tripathi, V.3
Colasse, S.4
Nakamura, T.5
Xuan, Z.6
-
27
-
-
33748675254
-
An RNA gene expressed during cortical development evolved rapidly in humans
-
PMID:16915236
-
Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, et al. An RNA gene expressed during cortical development evolved rapidly in humans. Nature 2006; 443:167-72; PMID:16915236; http://dx.doi.org/10.1038/nature05113.
-
(2006)
Nature
, vol.443
, pp. 167-172
-
-
Pollard, K.S.1
Salama, S.R.2
Lambert, N.3
Lambot, M.A.4
Coppens, S.5
Pedersen, J.S.6
-
28
-
-
33747706117
-
Non-coding RNAs in the nervous system
-
PMID:16809366
-
Mehler MF, Mattick JS. Non-coding RNAs in the nervous system. J Physiol 2006; 575:333-41; PMID:16809366; http://dx.doi.org/10.1113/jphysiol.2006.113191.
-
(2006)
J Physiol
, vol.575
, pp. 333-341
-
-
Mehler, M.F.1
Mattick, J.S.2
-
29
-
-
76649122999
-
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
-
PMID:20137068
-
Mercer TR, Qureshi IA, Gokhan S, Dinger ME, Li G, Mattick JS, et al. Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. BMC Neurosci 2010; 11:14; PMID:20137068; http://dx.doi.org/10.1186/ 1471-2202-11-14.
-
(2010)
BMC Neurosci
, vol.11
, pp. 14
-
-
Mercer, T.R.1
Qureshi, I.A.2
Gokhan, S.3
Dinger, M.E.4
Li, G.5
Mattick, J.S.6
-
30
-
-
77952581350
-
Long non-coding RNAs in nervous system function and disease
-
PMID:20380817
-
Qureshi IA, Mattick JS, Mehler MF. Long non-coding RNAs in nervous system function and disease. Brain Res 2010; 1338:20-35; PMID:20380817; http://dx.doi.org/10.1016/j.brainres.2010.03.110.
-
(2010)
Brain Res
, vol.1338
, pp. 20-35
-
-
Qureshi, I.A.1
Mattick, J.S.2
Mehler, M.F.3
-
31
-
-
34249724360
-
Noncoding RNAs and RNA editing in brain development, functional diversification and neurological disease
-
PMID:17615389
-
Mehler MF, Mattick JS. Noncoding RNAs and RNA editing in brain development, functional diversification and neurological disease. Physiol Rev 2007; 87:799-823; PMID:17615389; http://dx.doi.org/10.1152/physrev.00036.2006.
-
(2007)
Physiol Rev
, vol.87
, pp. 799-823
-
-
Mehler, M.F.1
Mattick, J.S.2
-
32
-
-
58149263391
-
Epigenetics and the nervous system
-
PMID:19107999
-
Mehler MF. Epigenetics and the nervous system. Ann Neurol 2008; 64:602-17; PMID:19107999; http://dx.doi.org/10.1002/ana.21595.
-
(2008)
Ann Neurol
, vol.64
, pp. 602-617
-
-
Mehler, M.F.1
-
33
-
-
73949085491
-
Non-coding RNAs: Regulators of disease
-
PMID:19882673
-
Taft RJ, Pang KC, Mercer TR, Dinger M, Mattick JS. Non-coding RNAs: regulators of disease. J Pathol 2010; 220:126-39; PMID:19882673; http://dx.doi.org/10.1002/path.2638.
-
(2010)
J Pathol
, vol.220
, pp. 126-139
-
-
Taft, R.J.1
Pang, K.C.2
Mercer, T.R.3
Dinger, M.4
Mattick, J.S.5
-
34
-
-
70450255155
-
Understanding microRNAs in neurodegeneration
-
PMID:19904280
-
Eacker SM, Dawson TM, Dawson VL. Understanding microRNAs in neurodegeneration. Nat Rev Neurosci 2009; 10:837-41; PMID:19904280; http://dx.doi.org/10.1038/nrn2726.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 837-841
-
-
Eacker, S.M.1
Dawson, T.M.2
Dawson, V.L.3
-
35
-
-
81355142141
-
Non-coding RNAs in human disease
-
PMID:22094949
-
Esteller M. Non-coding RNAs in human disease. Nat Rev Genet 2011; 12:861-74; PMID:22094949; http://dx.doi.org/10.1038/nrg3074.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 861-874
-
-
Esteller, M.1
-
36
-
-
33751254116
-
The neuronal microRNA system
-
PMID:17115073
-
Kosik KS. The neuronal microRNA system. Nat Rev Neurosci 2006; 7:911-20; PMID:17115073; http://dx.doi.org/10.1038/nrn2037.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 911-920
-
-
Kosik, K.S.1
-
37
-
-
77952574649
-
MicroRNA dysregulation in psychiatric disease
-
PMID:20303342
-
Miller BH, Wahlestedt C. MicroRNA dysregulation in psychiatric disease. Brain Res 2010; 1338:89-99; PMID:20303342; http://dx.doi.org/10.1016/j.brainres. 2010.03.035.
-
(2010)
Brain Res
, vol.1338
, pp. 89-99
-
-
Miller, B.H.1
Wahlestedt, C.2
-
38
-
-
77649144557
-
Repeat instability as the basis for human diseases and as a potential target for therapy
-
PMID:20177394
-
López Castel A, Cleary JD, Pearson CE. Repeat instability as the basis for human diseases and as a potential target for therapy. Nat Rev Mol Cell Biol 2010; 11:165-70; PMID:20177394; http://dx.doi.org/10.1038/nrm2854.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 165-170
-
-
López Castel, A.1
Cleary, J.D.2
Pearson, C.E.3
-
39
-
-
34250878426
-
Expandable DNA repeats and human disease
-
PMID:17581576
-
Mirkin SM. Expandable DNA repeats and human disease. Nature 2007; 447:932-40; PMID:17581576; http://dx.doi.org/10.1038/nature05977.
-
(2007)
Nature
, vol.447
, pp. 932-940
-
-
Mirkin, S.M.1
-
40
-
-
33745545413
-
Bidirectional expression of CUG and CAG expansion transcripts and intranuclearpolyglutamine inclusions in spinocerebellar ataxia type 8
-
PMID:16804541
-
Moseley ML, Zu T, Ikeda Y, Gao W, Mosemiller AK, Daughters RS, et al. Bidirectional expression of CUG and CAG expansion transcripts and intranuclearpolyglutamine inclusions in spinocerebellar ataxia type 8. Nat Genet 2006; 38:758-69; PMID:16804541; http://dx.doi.org/10.1038/ng1827.
-
(2006)
Nat Genet
, vol.38
, pp. 758-769
-
-
Moseley, M.L.1
Zu, T.2
Ikeda, Y.3
Gao, W.4
Mosemiller, A.K.5
Daughters, R.S.6
-
41
-
-
27644525713
-
Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF
-
PMID:16285929
-
Cho DH, Thienes CP, Mahoney SE, Analau E, Filippova GN, Tapscott SJ. Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. Mol Cell 2005; 20:483-9; PMID:16285929; http://dx.doi.org/10.1016/j.molcel.2005.09.002.
-
(2005)
Mol Cell
, vol.20
, pp. 483-489
-
-
Cho, D.H.1
Thienes, C.P.2
Mahoney, S.E.3
Analau, E.4
Filippova, G.N.5
Tapscott, S.J.6
-
42
-
-
16944364511
-
Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion
-
PMID:9288099
-
David G, Abbas N, Stevanin G, Dürr A, Yvert G, Cancel G, et al. Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nat Genet 1997; 17:65-70; PMID:9288099; http://dx.doi.org/10.1038/ng0997-65.
-
(1997)
Nat Genet
, vol.17
, pp. 65-70
-
-
David, G.1
Abbas, N.2
Stevanin, G.3
Dürr, A.4
Yvert, G.5
Cancel, G.6
-
43
-
-
16144363213
-
An expanded CAG repeat sequence in spinocerebellar ataxia type 7
-
PMID:8908515
-
Lindblad K, Savontaus ML, Stevanin G, Holmberg M, Digre K, Zander C, et al. An expanded CAG repeat sequence in spinocerebellar ataxia type 7. Genome Res 1996; 6:965-71; PMID:8908515; http://dx.doi.org/10.1101/gr.6.10.965.
-
(1996)
Genome Res
, vol.6
, pp. 965-971
-
-
Lindblad, K.1
Savontaus, M.L.2
Stevanin, G.3
Holmberg, M.4
Digre, K.5
Zander, C.6
-
44
-
-
79959306523
-
CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA
-
PMID:21689595
-
Sopher BL, Ladd PD, Pineda VV, Libby RT, Sunkin SM, Hurley JB, et al. CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA. Neuron 2011; 70:1071-84; PMID:21689595; http://dx.doi.org/10.1016/j.neuron.2011.05.027.
-
(2011)
Neuron
, vol.70
, pp. 1071-1084
-
-
Sopher, B.L.1
Ladd, P.D.2
Pineda, V.V.3
Libby, R.T.4
Sunkin, S.M.5
Hurley, J.B.6
-
45
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
PMID:17512414
-
Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, et al. High-resolution profiling of histone methylations in the human genome. Cell 2007; 129:823-37; PMID:17512414; http://dx.doi.org/10.1016/j.cell.2007.05.009.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
-
46
-
-
35348924169
-
Genetics and epigenetics of the multifunctional protein CTCF
-
PMID:17950379
-
Filippova GN. Genetics and epigenetics of the multifunctional protein CTCF. Curr Top Dev Biol 2008; 80:337-60; PMID:17950379; http://dx.doi.org/10. 1016/S0070-2153(07)80009-3.
-
(2008)
Curr Top Dev Biol
, vol.80
, pp. 337-360
-
-
Filippova, G.N.1
-
47
-
-
70149112363
-
RNA gain-of-function in spinocerebellar ataxia type 8
-
PMID:19680539
-
Daughters RS, Tuttle DL, Gao W, Ikeda Y, Moseley ML, Ebner TJ, et al. RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet 2009; 5:1000600; PMID:19680539; http://dx.doi.org/10.1371/journal.pgen.1000600.
-
(2009)
PLoS Genet
, vol.5
, pp. 1000600
-
-
Daughters, R.S.1
Tuttle, D.L.2
Gao, W.3
Ikeda, Y.4
Moseley, M.L.5
Ebner, T.J.6
-
48
-
-
61449095749
-
Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci
-
PMID:19203395
-
Chen IC, Lin HY, Lee GC, Kao SH, Chen CM, Wu YR, et al. Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci. BMC Mol Biol 2009; 10:9; PMID:19203395; http://dx.doi.org/10.1186/ 1471-2199-10-9.
-
(2009)
BMC Mol Biol
, vol.10
, pp. 9
-
-
Chen, I.C.1
Lin, H.Y.2
Lee, G.C.3
Kao, S.H.4
Chen, C.M.5
Wu, Y.R.6
-
49
-
-
25844438495
-
Repeat instability: Mechanisms of dynamic mutations
-
PMID:16205713
-
Pearson CE, Nichol Edamura K, Cleary JD. Repeat instability: mechanisms of dynamic mutations. Nat Rev Genet 2005; 6:729-42; PMID:16205713; http://dx.doi.org/10.1038/nrg1689.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 729-742
-
-
Pearson, C.E.1
Nichol Edamura, K.2
Cleary, J.D.3
-
50
-
-
0035451090
-
CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease
-
PMID:11525835
-
Ohlsson R, Renkawitz R, Lobanenkov V. CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet 2001; 17:520-7; PMID:11525835; http://dx.doi.org/10.1016/S0168-9525(01)02366-6.
-
(2001)
Trends Genet
, vol.17
, pp. 520-527
-
-
Ohlsson, R.1
Renkawitz, R.2
Lobanenkov, V.3
-
51
-
-
77953887860
-
Partners in crime: Bidirectional transcription in unstable microsatellite disease
-
PMID:20368264
-
Batra R, Charizanis K, Swanson MS. Partners in crime: bidirectional transcription in unstable microsatellite disease. Hum Mol Genet 2010; 19:77-82; PMID:20368264; http://dx.doi.org/10.1093/hmg/ddq132.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 77-82
-
-
Batra, R.1
Charizanis, K.2
Swanson, M.S.3
-
52
-
-
0346243805
-
Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios
-
PMID:14671302
-
Clark AG, Glanowski S, Nielsen R, Thomas PD, Kejariwal A, Todd MA, et al. Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. Science 2003; 302:1960-3; PMID:14671302; http://dx.doi.org/10.1126/science. 1088821.
-
(2003)
Science
, vol.302
, pp. 1960-1963
-
-
Clark, A.G.1
Glanowski, S.2
Nielsen, R.3
Thomas, P.D.4
Kejariwal, A.5
Todd, M.A.6
-
53
-
-
29444452921
-
Molecular signatures of natural selection
-
PMID:16285858
-
Nielsen R. Molecular signatures of natural selection. Annu Rev Genet 2005; 39:197-218; PMID:16285858; http://dx.doi.org/10.1146/annurev.genet.39. 073003.112420.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 197-218
-
-
Nielsen, R.1
-
54
-
-
79951481957
-
Initial impact of the sequencing of the human genome
-
PMID:21307931
-
Lander ES. Initial impact of the sequencing of the human genome. Nature 2011; 470:187-97; PMID:21307931; http://dx.doi.org/10.1038/nature09792.
-
(2011)
Nature
, vol.470
, pp. 187-197
-
-
Lander, E.S.1
-
55
-
-
23744458086
-
Evolutionarily conserved elements in vertebrate, insect, worm and yeast genomes
-
PMID:16024819
-
Siepel A, Bejerano G, Pedersen JS, Hinrichs AS, Hou M, Rosenbloom K, et al. Evolutionarily conserved elements in vertebrate, insect, worm and yeast genomes. Genome Res 2005; 15:1034-50; PMID:16024819; http://dx.doi.org/10.1101/ gr.3715005.
-
(2005)
Genome Res
, vol.15
, pp. 1034-1050
-
-
Siepel, A.1
Bejerano, G.2
Pedersen, J.S.3
Hinrichs, A.S.4
Hou, M.5
Rosenbloom, K.6
-
56
-
-
34047130812
-
Role of brain-derived neurotrophic factor in Huntington's disease
-
PMID:17379385
-
Zuccato C, Cattaneo E. Role of brain-derived neurotrophic factor in Huntington's disease. ProgNeurobiol 2007; 81:294-330; PMID:17379385; http://dx.doi.org/10.1016/j.pneurobio.2007.01.003.
-
(2007)
ProgNeurobiol
, vol.81
, pp. 294-330
-
-
Zuccato, C.1
Cattaneo, E.2
-
57
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
PMID:17540862
-
Johnson DS, Mortazavi A, Myers RM, Wold B. Genome-wide mapping of in vivo protein-DNA interactions. Science 2007; 316:1497-502; PMID:17540862; http://dx.doi.org/10.1126/science.1141319.
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
Wold, B.4
-
58
-
-
33645323814
-
Imprinted genes, placental development and fetal growth
-
PMID:16612114
-
Fowden AL, Sibley C, Reik W, Constancia M. Imprinted genes, placental development and fetal growth. Horm Res 2006; 65:50-8; PMID:16612114; http://dx.doi.org/10.1159/000091506.
-
(2006)
Horm Res
, vol.65
, pp. 50-58
-
-
Fowden, A.L.1
Sibley, C.2
Reik, W.3
Constancia, M.4
-
59
-
-
16844368169
-
Imprinted gene expression in the brain
-
PMID:15820547
-
Davies W, Isles AR, Wilkinson LS. Imprinted gene expression in the brain. Neurosci Biobehav Rev 2005; 29:421-30; PMID:15820547; http://dx.doi.org/10. 1016/j.neubiorev.2004.11.007.
-
(2005)
Neurosci Biobehav Rev
, vol.29
, pp. 421-430
-
-
Davies, W.1
Isles, A.R.2
Wilkinson, L.S.3
-
60
-
-
35549001312
-
Genomic imprinting effects on brain development and function
-
PMID:17925812
-
Wilkinson LS, Davies W, Isles AR. Genomic imprinting effects on brain development and function. Nat Rev Neurosci 2007; 8:832-43; PMID:17925812; http://dx.doi.org/10.1038/nrn2235.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 832-843
-
-
Wilkinson, L.S.1
Davies, W.2
Isles, A.R.3
-
61
-
-
3042567235
-
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees
-
PMID:15219468
-
Schulze TG, Buervenich S, Badner JA, Steele CJ, Detera-Wadleigh SD, Dick D, et al. Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees. Biol Psychiatry 2004; 56:18-23; PMID:15219468; http://dx.doi.org/10.1016/j.biopsych.2004.04.004.
-
(2004)
Biol Psychiatry
, vol.56
, pp. 18-23
-
-
Schulze, T.G.1
Buervenich, S.2
Badner, J.A.3
Steele, C.J.4
Detera-Wadleigh, S.D.5
Dick, D.6
-
62
-
-
33749007122
-
Epigenetics of autism spectrum disorders
-
PMID:16987877
-
Schanen NC. Epigenetics of autism spectrum disorders. Hum Mol Genet 2006; 15:138-50; PMID:16987877; http://dx.doi.org/10.1093/hmg/ddl213.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 138-150
-
-
Schanen, N.C.1
-
63
-
-
0348013121
-
Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11
-
PMID:14583442
-
Francks C, DeLisi LE, Shaw SH, Fisher SE, Richardson AJ, Stein JF, et al. Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11. Hum Mol Genet 2003; 12:3225-30; PMID:14583442; http://dx.doi.org/10.1093/hmg/ddg362.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 3225-3230
-
-
Francks, C.1
DeLisi, L.E.2
Shaw, S.H.3
Fisher, S.E.4
Richardson, A.J.5
Stein, J.F.6
-
64
-
-
24644472515
-
Antisense transcription in the mammalian transcriptome
-
RIKEN Genome Exploration Research Group; Genome Science Group (Genome Network Project Core Group); FANTOM Consortium PMID:16141073
-
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, et al.; RIKEN Genome Exploration Research Group; Genome Science Group (Genome Network Project Core Group); FANTOM Consortium. Antisense transcription in the mammalian transcriptome. Science 2005; 309:1564-6; PMID:16141073; http://dx.doi.org/10.1126/science.1112009.
-
(2005)
Science
, vol.309
, pp. 1564-1566
-
-
Katayama, S.1
Tomaru, Y.2
Kasukawa, T.3
Waki, K.4
Nakanishi, M.5
Nakamura, M.6
-
65
-
-
77955406842
-
Angelman syndrome, a genomic imprinting disorder of the brain
-
PMID:20668179
-
Chamberlain SJ, Lalande M. Angelman syndrome, a genomic imprinting disorder of the brain. J Neurosci 2010; 30:9958-63; PMID:20668179; http://dx.doi.org/10.1523/JNEUROSCI.1728-10.2010.
-
(2010)
J Neurosci
, vol.30
, pp. 9958-9963
-
-
Chamberlain, S.J.1
Lalande, M.2
-
66
-
-
0242432463
-
Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a
-
PMID:12668607
-
Yamasaki K, Joh K, Ohta T, Masuzaki H, Ishimaru T, Mukai T, et al. Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a. Hum Mol Genet 2003; 12:837-47; PMID:12668607; http://dx.doi.org/10.1093/hmg/ddg106.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 837-847
-
-
Yamasaki, K.1
Joh, K.2
Ohta, T.3
Masuzaki, H.4
Ishimaru, T.5
Mukai, T.6
-
67
-
-
0031012849
-
UBE3A/E6-AP mutations cause Angelman syndrome
-
PMID:8988171
-
Kishino T, Lalande M, Wagstaff J. UBE3A/E6-AP mutations cause Angelman syndrome. Nat Genet 1997; 15:70-3; PMID:8988171; http://dx.doi.org/10.1038/ ng0197-70.
-
(1997)
Nat Genet
, vol.15
, pp. 70-73
-
-
Kishino, T.1
Lalande, M.2
Wagstaff, J.3
-
68
-
-
0031031570
-
De novo truncating mutations in E6-AP ubiquitin-protein ligase gene (UBE3A) in Angelman syndrome
-
PMID:8988172
-
Matsuura T, Sutcliffe JS, Fang P, Galjaard RJ, Jiang YH, Benton CS, et al. De novo truncating mutations in E6-AP ubiquitin-protein ligase gene (UBE3A) in Angelman syndrome. Nat Genet 1997; 15:74-7; PMID:8988172; http://dx.doi.org/10.1038/ng0197-74.
-
(1997)
Nat Genet
, vol.15
, pp. 74-77
-
-
Matsuura, T.1
Sutcliffe, J.S.2
Fang, P.3
Galjaard, R.J.4
Jiang, Y.H.5
Benton, C.S.6
-
69
-
-
84855807682
-
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons
-
PMID:22190039
-
Huang HS, Allen JA, Mabb AM, King IF, Miriyala J, Taylor-Blake B, et al. Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons. Nature 2011; 481:185-9; PMID:22190039; http://dx.doi.org/10.1038/nature10726.
-
(2011)
Nature
, vol.481
, pp. 185-189
-
-
Huang, H.S.1
Allen, J.A.2
Mabb, A.M.3
King, I.F.4
Miriyala, J.5
Taylor-Blake, B.6
-
70
-
-
80052678741
-
Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis
-
PMID:21785702
-
Modarresi F, Faghihi MA, Patel NS, Sahagan BG, Wahlestedt C, Lopez-Toledano MA. Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis 2011; 2011:929042; PMID:21785702.
-
(2011)
Int J Alzheimers Dis
, vol.2011
, pp. 929042
-
-
Modarresi, F.1
Faghihi, M.A.2
Patel, N.S.3
Sahagan, B.G.4
Wahlestedt, C.5
Lopez-Toledano, M.A.6
-
71
-
-
33646473694
-
Complex Loci in human and mouse genomes
-
PMID:16683030
-
Engström PG, Suzuki H, Ninomiya N, Akalin A, Sessa L, Lavorgna G, et al. Complex Loci in human and mouse genomes. PLoS Genet 2006; 2:47; PMID:16683030; http://dx.doi.org/10.1371/journal.pgen.0020047.
-
(2006)
PLoS Genet
, vol.2
, pp. 47
-
-
Engström, P.G.1
Suzuki, H.2
Ninomiya, N.3
Akalin, A.4
Sessa, L.5
Lavorgna, G.6
-
72
-
-
0036731660
-
The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system
-
PMID:12213198
-
Vincent JB, Petek E, Thevarkunnel S, Kolozsvari D, Cheung J, Patel M, et al. The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system. Genomics 2002; 80:283-94; PMID:12213198; http://dx.doi.org/10.1006/geno.2002.6835.
-
(2002)
Genomics
, vol.80
, pp. 283-294
-
-
Vincent, J.B.1
Petek, E.2
Thevarkunnel, S.3
Kolozsvari, D.4
Cheung, J.5
Patel, M.6
-
73
-
-
0034702026
-
Disruption of two novel genes by a translocation co-segregating with schizophrenia
-
PMID:10814723
-
Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 2000; 9:1415-23; PMID:10814723; http://dx.doi.org/10.1093/hmg/9.9.1415.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1415-1423
-
-
Millar, J.K.1
Wilson-Annan, J.C.2
Anderson, S.3
Christie, S.4
Taylor, M.S.5
Semple, C.A.6
-
74
-
-
0034927864
-
Schizophrenia and affective disorders - Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
-
PMID:11443544
-
Blackwood DH, Fordyce A, Walker MT, St. Clair DM, Porteous DJ, Muir WJ. Schizophrenia and affective disorders - cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet 2001; 69:428-33; PMID:11443544; http://dx.doi.org/10.1086/321969.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 428-433
-
-
Blackwood, D.H.1
Fordyce, A.2
Walker, M.T.3
St Clair, D.M.4
Porteous, D.J.5
Muir, W.J.6
-
75
-
-
0037269198
-
Mouse brain gene expression changes after acute and chronic amphetamine
-
PMID:12558987
-
Sokolov BP, Polesskaya OO, Uhl GR. Mouse brain gene expression changes after acute and chronic amphetamine. J Neurochem 2003; 84:244-52; PMID:12558987; http://dx.doi.org/10.1046/j.1471-4159.2003.01523.x.
-
(2003)
J Neurochem
, vol.84
, pp. 244-252
-
-
Sokolov, B.P.1
Polesskaya, O.O.2
Uhl, G.R.3
-
76
-
-
68149182666
-
Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry
-
PMID:19620975
-
Bond AM, Vangompel MJ, Sametsky EA, Clark MF, Savage JC, Disterhoft JF, et al. Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nat Neurosci 2009; 12:1020-7; PMID:19620975; http://dx.doi.org/10.1038/nn.2371.
-
(2009)
Nat Neurosci
, vol.12
, pp. 1020-1027
-
-
Bond, A.M.1
Vangompel, M.J.2
Sametsky, E.A.3
Clark, M.F.4
Savage, J.C.5
Disterhoft, J.F.6
-
77
-
-
84855180166
-
GABAergic circuit development and its implication for CNS disorders
-
PMID:22013542
-
Di Cristo G, Pizzorusso T, Cancedda L, Sernagor E. GABAergic circuit development and its implication for CNS disorders. Neural Plast 2011; 2011:623705; PMID:22013542; http://dx.doi.org/10.1155/2011/623705.
-
(2011)
Neural Plast
, vol.2011
, pp. 623705
-
-
Di Cristo, G.1
Pizzorusso, T.2
Cancedda, L.3
Sernagor, E.4
-
78
-
-
77955323879
-
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
-
PMID:20673990
-
Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 2010; 142:409-19; PMID:20673990; http://dx.doi.org/10.1016/j.cell.2010.06.040.
-
(2010)
Cell
, vol.142
, pp. 409-419
-
-
Huarte, M.1
Guttman, M.2
Feldser, D.3
Garber, M.4
Koziol, M.J.5
Kenzelmann-Broz, D.6
-
79
-
-
79959756263
-
Extensive and coordinated transcription of noncoding RNAs within cell cycle promoters
-
PMID:21642992
-
Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, et al. Extensive and coordinated transcription of noncoding RNAs within cell cycle promoters. Nat Genet 2011; 43:621-9; PMID:21642992; http://dx.doi.org/10.1038/ng.848.
-
(2011)
Nat Genet
, vol.43
, pp. 621-629
-
-
Hung, T.1
Wang, Y.2
Lin, M.F.3
Koegel, A.K.4
Kotake, Y.5
Grant, G.D.6
-
80
-
-
70449578270
-
Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation
-
PMID:19888342
-
Abrajano JJ, Qureshi IA, Gokhan S, Zheng D, Bergman A, Mehler MF. Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation. PLoS One 2009; 4:7665; PMID:19888342; http://dx.doi.org/10.1371/journal.pone.0007665.
-
(2009)
PLoS One
, vol.4
, pp. 7665
-
-
Abrajano, J.J.1
Qureshi, I.A.2
Gokhan, S.3
Zheng, D.4
Bergman, A.5
Mehler, M.F.6
-
81
-
-
77954572735
-
Long noncoding RNA as modular scaffold of histone modification complexes
-
PMID:20616235
-
Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science 2010; 329:689-93; PMID:20616235; http://dx.doi.org/10.1126/science.1192002.
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
Manor, O.2
Wan, Y.3
Mosammaparast, N.4
Wang, J.K.5
Lan, F.6
-
82
-
-
33748921564
-
REST in good times and bad: Roles in tumor suppressor and oncogenic activities
-
PMID:16929174
-
Majumder S. REST in good times and bad: roles in tumor suppressor and oncogenic activities. Cell Cycle 2006; 5:1929-35; PMID:16929174; http://dx.doi.org/10.4161/cc.5.17.2982.
-
(2006)
Cell Cycle
, vol.5
, pp. 1929-1935
-
-
Majumder, S.1
-
83
-
-
0033942317
-
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
-
PMID:10888935
-
Lawinger P, Venugopal R, Guo ZS, Immaneni A, Sengupta D, Lu W, et al. The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells. Nat Med 2000; 6:826-31; PMID:10888935; http://dx.doi.org/10.1038/77565.
-
(2000)
Nat Med
, vol.6
, pp. 826-831
-
-
Lawinger, P.1
Venugopal, R.2
Guo, Z.S.3
Immaneni, A.4
Sengupta, D.5
Lu, W.6
-
84
-
-
24044505984
-
Transcriptional regulation: Cancer, neurons and the REST
-
PMID:16139198
-
Coulson JM. Transcriptional regulation: cancer, neurons and the REST. Curr Biol 2005; 15:665-8; PMID:16139198; http://dx.doi.org/10.1016/j.cub.2005. 08.032.
-
(2005)
Curr Biol
, vol.15
, pp. 665-668
-
-
Coulson, J.M.1
-
85
-
-
55449105221
-
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
-
PMID:18974828
-
Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet 2008; 4:1000242; PMID:18974828; http://dx.doi.org/10.1371/journal.pgen.1000242.
-
(2008)
PLoS Genet
, vol.4
, pp. 1000242
-
-
Ku, M.1
Koche, R.P.2
Rheinbay, E.3
Mendenhall, E.M.4
Endoh, M.5
Mikkelsen, T.S.6
-
86
-
-
55349109963
-
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
-
PMID:18974356
-
Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science 2008; 322:750-6; PMID:18974356; http://dx.doi.org/10.1126/science.1163045.
-
(2008)
Science
, vol.322
, pp. 750-756
-
-
Zhao, J.1
Sun, B.K.2
Erwin, J.A.3
Song, J.J.4
Lee, J.T.5
-
87
-
-
79955468280
-
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
-
PMID:21151178
-
Kotake Y, Nakagawa T, Kitagawa K, Suzuki S, Liu N, Kitagawa M, et al. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene 2011; 30:1956-62; PMID:21151178; http://dx.doi.org/10.1038/onc.2010.568.
-
(2011)
Oncogene
, vol.30
, pp. 1956-1962
-
-
Kotake, Y.1
Nakagawa, T.2
Kitagawa, K.3
Suzuki, S.4
Liu, N.5
Kitagawa, M.6
-
88
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
PMID:20393566
-
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010; 464:1071-6; PMID:20393566; http://dx.doi.org/10.1038/nature08975.
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
-
89
-
-
77955085750
-
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
-
PMID:20601953
-
Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 2010; 42:722-6; PMID:20601953; http://dx.doi.org/10.1038/ ng.621.
-
(2010)
Nat Genet
, vol.42
, pp. 722-726
-
-
Ernst, T.1
Chase, A.J.2
Score, J.3
Hidalgo-Curtis, C.E.4
Bryant, C.5
Jones, A.V.6
-
90
-
-
79955513100
-
Aberrations of EZH2 in cancer
-
PMID:21367748
-
Chase A, Cross NC. Aberrations of EZH2 in cancer. Clin Cancer Res 2011; 17:2613-8; PMID:21367748; http://dx.doi.org/10.1158/1078-0432.CCR-10-2156.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2613-2618
-
-
Chase, A.1
Cross, N.C.2
-
91
-
-
79959416877
-
Enhancer of Zeste 2 (EZH2) is upregulated in malignant gliomas and in glioma stem-like cells
-
PMID:20946108
-
Orzan F, Pellegatta S, Poliani PL, Pisati F, Caldera V, Menghi F, et al. Enhancer of Zeste 2 (EZH2) is upregulated in malignant gliomas and in glioma stem-like cells. Neuropathol Appl Neurobiol 2011; 37:381-94; PMID:20946108; http://dx.doi.org/10.1111/j.1365-2990.2010.01132.x.
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, pp. 381-394
-
-
Orzan, F.1
Pellegatta, S.2
Poliani, P.L.3
Pisati, F.4
Caldera, V.5
Menghi, F.6
-
92
-
-
0345172377
-
A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells
-
PMID:14602737
-
Zhang X, Zhou Y, Mehta KR, Danila DC, Scolavino S, Johnson SR, et al. A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells. J Clin Endocrinol Metab 2003; 88:5119-26; PMID:14602737; http://dx.doi.org/10. 1210/jc.2003-030222.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5119-5126
-
-
Zhang, X.1
Zhou, Y.2
Mehta, K.R.3
Danila, D.C.4
Scolavino, S.5
Johnson, S.R.6
-
93
-
-
0023091971
-
Identification of an amplified, highly expressed gene in a human glioma
-
PMID:3563490
-
Kinzler KW, Bigner SH, Bigner DD, Trent JM, Law ML, O'Brien SJ, et al. Identification of an amplified, highly expressed gene in a human glioma. Science 1987; 236:70-3; PMID:3563490; http://dx.doi.org/10.1126/science.3563490.
-
(1987)
Science
, vol.236
, pp. 70-73
-
-
Kinzler, K.W.1
Bigner, S.H.2
Bigner, D.D.3
Trent, J.M.4
Law, M.L.5
O'Brien, S.J.6
-
94
-
-
55849130676
-
A novel H19 antisense RNA overexpressed in breast cancer contributes to paternal IGF2 expression
-
PMID:18794369
-
Berteaux N, Aptel N, Cathala G, Genton C, Coll J, Daccache A, et al. A novel H19 antisense RNA overexpressed in breast cancer contributes to paternal IGF2 expression. Mol Cell Biol 2008; 28:6731-45; PMID:18794369; http://dx.doi.org/10.1128/MCB.02103-07.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6731-6745
-
-
Berteaux, N.1
Aptel, N.2
Cathala, G.3
Genton, C.4
Coll, J.5
Daccache, A.6
-
95
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
PMID:75545
-
Zamecnik PC, Stephenson ML. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA 1978; 75:280-4; PMID:75545; http://dx.doi.org/10.1073/pnas.75.1.280.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
96
-
-
79951602633
-
Targeted therapy for high-grade glioma with the TGFβ2 inhibitor trabedersen: Results of a randomized and controlled phase IIb study
-
Trabedersen Glioma Study Group PMID:20980335
-
Bogdahn U, Hau P, Stockhammer G, Venkataramana NK, Mahapatra AK, Suri A, et al.; Trabedersen Glioma Study Group. Targeted therapy for high-grade glioma with the TGFβ2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. Neuro Oncol 2011; 13:132-42; PMID:20980335; http://dx.doi.org/10.1093/neuonc/noq142.
-
(2011)
Neuro Oncol
, vol.13
, pp. 132-142
-
-
Bogdahn, U.1
Hau, P.2
Stockhammer, G.3
Venkataramana, N.K.4
Mahapatra, A.K.5
Suri, A.6
-
97
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
PMID:11373684
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-8; PMID:11373684; http://dx.doi.org/10.1038/ 35078107.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
98
-
-
84860353437
-
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
-
In press; PMID:22446693
-
Modarresi F, Faghihi MA, Lopez-Toledano MA, Fatemi RP, Magistri M, Brothers SP, et al. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol 2012; In press; PMID:22446693; http://dx.doi.org/10.1038/nbt.2158.
-
(2012)
Nat Biotechnol
-
-
Modarresi, F.1
Faghihi, M.A.2
Lopez-Toledano, M.A.3
Fatemi, R.P.4
Magistri, M.5
Brothers, S.P.6
-
99
-
-
0030829919
-
Inhibition of coagulation by a phosphorothioate oligonucleotide
-
PMID:9361909
-
Henry SP, Novotny W, Leeds J, Auletta C, Kornbrust DJ. Inhibition of coagulation by a phosphorothioate oligonucleotide. Antisense Nucleic Acid Drug Dev 1997; 7:503-10; PMID:9361909; http://dx.doi.org/10.1089/oli.1.1997.7.503.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 503-510
-
-
Henry, S.P.1
Novotny, W.2
Leeds, J.3
Auletta, C.4
Kornbrust, D.J.5
-
100
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
PMID:7700380
-
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995; 374:546-9; PMID:7700380; http://dx.doi.org/10.1038/374546a0.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
-
101
-
-
0029738445
-
Activation of human B cells by phosphorothioate-oligodeoxynucleotides
-
PMID:8787674
-
Liang H, Nishioka Y, Reich CF, Pisetsky DS, Lipsky PE. Activation of human B cells by phosphorothioate-oligodeoxynucleotides. J Clin Invest 1996; 98:1119-29; PMID:8787674; http://dx.doi.org/10.1172/JCI118894.
-
(1996)
J Clin Invest
, vol.98
, pp. 1119-1129
-
-
Liang, H.1
Nishioka, Y.2
Reich, C.F.3
Pisetsky, D.S.4
Lipsky, P.E.5
-
102
-
-
0032708654
-
Oligonucleotides tethered to a short polyguanylic acid stretch are targeted to macrophages: Enhanced antiviral activity of a vesicular stomatitis virus-specific antisense oligonucleotide
-
PMID:10543748
-
Prasad V, Hashim S, Mukhopadhyay A, Basu SK, Roy RP. Oligonucleotides tethered to a short polyguanylic acid stretch are targeted to macrophages: enhanced antiviral activity of a vesicular stomatitis virus-specific antisense oligonucleotide. Antimicrob Agents Chemother 1999; 43:2689-96; PMID:10543748.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 2689-2696
-
-
Prasad, V.1
Hashim, S.2
Mukhopadhyay, A.3
Basu, S.K.4
Roy, R.P.5
-
103
-
-
0031457918
-
Toxicologic effects of an oligodeoxynucleotide-phosphorothioate and its analogs following intravenous administration in rats
-
PMID:9450915
-
Agrawal S, Zhao Q, Jiang Z, Oliver C, Giles H, Heath J, et al. Toxicologic effects of an oligodeoxynucleotide-phosphorothioate and its analogs following intravenous administration in rats. Antisense Nucleic Acid Drug Dev 1997; 7:575-84; PMID:9450915; http://dx.doi.org/10.1089/oli.1.1997.7.575.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 575-584
-
-
Agrawal, S.1
Zhao, Q.2
Jiang, Z.3
Oliver, C.4
Giles, H.5
Heath, J.6
-
104
-
-
0027207494
-
Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions
-
PMID:8487863
-
Wahlestedt C, Golanov E, Yamamoto S, Yee F, Ericson H, Yoo H, et al. Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature 1993; 363:260-3; PMID:8487863; http://dx.doi.org/10.1038/363260a0.
-
(1993)
Nature
, vol.363
, pp. 260-263
-
-
Wahlestedt, C.1
Golanov, E.2
Yamamoto, S.3
Yee, F.4
Ericson, H.5
Yoo, H.6
-
105
-
-
0027450169
-
Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides
-
PMID:8380941
-
Wahlestedt C, Pich EM, Koob GF, Yee F, Heilig M. Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science 1993; 259:528-31; PMID:8380941; http://dx.doi.org/10.1126/science.8380941.
-
(1993)
Science
, vol.259
, pp. 528-531
-
-
Wahlestedt, C.1
Pich, E.M.2
Koob, G.F.3
Yee, F.4
Heilig, M.5
-
106
-
-
34247611037
-
Antisense inhibition at the beta-secretase-site of beta-amyloid precursor protein reduces cerebral amyloid and acetyl cholinesterase activity in Tg2576
-
PMID:17303345
-
Chauhan NB, Siegel GJ. Antisense inhibition at the beta-secretase-site of beta-amyloid precursor protein reduces cerebral amyloid and acetyl cholinesterase activity in Tg2576. Neuroscience 2007; 146:143-51; PMID:17303345; http://dx.doi.org/10.1016/j.neuroscience.2007.01.008.
-
(2007)
Neuroscience
, vol.146
, pp. 143-151
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
107
-
-
33645519567
-
An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
-
PMID:16191203
-
Luo MC, Zhang DQ, Ma SW, Huang YY, Shuster SJ, Porreca F, et al. An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons. Mol Pain 2005; 1:29; PMID:16191203; http://dx.doi.org/10. 1186/1744-8069-1-29.
-
(2005)
Mol Pain
, vol.1
, pp. 29
-
-
Luo, M.C.1
Zhang, D.Q.2
Ma, S.W.3
Huang, Y.Y.4
Shuster, S.J.5
Porreca, F.6
-
108
-
-
79952348568
-
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy
-
PMID:21368223
-
Passini MA, Bu J, Richards AM, Kinnecom C, Sardi SP, Stanek LM, et al. Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy. SciTransl Med 2011; 3:72; PMID:21368223; http://dx.doi.org/10.1126/scitranslmed.3001777.
-
(2011)
SciTransl Med
, vol.3
, pp. 72
-
-
Passini, M.A.1
Bu, J.2
Richards, A.M.3
Kinnecom, C.4
Sardi, S.P.5
Stanek, L.M.6
-
109
-
-
33746667851
-
Antisense oligonucleotide therapy for neurodegenerative disease
-
PMID:16878173
-
Smith RA, Miller TM, Yamanaka K, Monia BP, Condon TP, Hung G, et al. Antisense oligonucleotide therapy for neurodegenerative disease. J Clin Invest 2006; 116:2290-6; PMID:16878173; http://dx.doi.org/10.1172/JCI25424.
-
(2006)
J Clin Invest
, vol.116
, pp. 2290-2296
-
-
Smith, R.A.1
Miller, T.M.2
Yamanaka, K.3
Monia, B.P.4
Condon, T.P.5
Hung, G.6
-
110
-
-
0028327150
-
Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor
-
PMID:8161452
-
Standifer KM, Chien CC, Wahlestedt C, Brown GP, Pasternak GW. Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor. Neuron 1994; 12:805-10; PMID:8161452; http://dx.doi.org/10.1016/0896-6273(94)90333-6.
-
(1994)
Neuron
, vol.12
, pp. 805-810
-
-
Standifer, K.M.1
Chien, C.C.2
Wahlestedt, C.3
Brown, G.P.4
Pasternak, G.W.5
-
111
-
-
10344228801
-
Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference
-
PMID:15569935
-
Thakker DR, Natt F, Hüsken D, Maier R, Müller M, van der Putten H, et al. Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference. Proc Natl Acad Sci USA 2004; 101:17270-5; PMID:15569935; http://dx.doi.org/10.1073/pnas. 0406214101.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17270-17275
-
-
Thakker, D.R.1
Natt, F.2
Hüsken, D.3
Maier, R.4
Müller, M.5
Van Der Putten, H.6
-
112
-
-
75849140535
-
Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth
-
PMID:19948956
-
Hasbi A, Fan T, Alijaniaram M, Nguyen T, Perreault ML, O'Dowd BF, et al. Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth. Proc Natl Acad Sci USA 2009; 106:21377-82; PMID:19948956; http://dx.doi.org/10.1073/pnas.0903676106.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21377-21382
-
-
Hasbi, A.1
Fan, T.2
Alijaniaram, M.3
Nguyen, T.4
Perreault, M.L.5
O'Dowd, B.F.6
-
113
-
-
77249140499
-
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear
-
PMID:20133801
-
Choi DC, Maguschak KA, Ye K, Jang SW, Myers KM, Ressler KJ. Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci USA 2010; 107:2675-80; PMID:20133801; http://dx.doi.org/10.1073/pnas.0909359107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2675-2680
-
-
Choi, D.C.1
Maguschak, K.A.2
Ye, K.3
Jang, S.W.4
Myers, K.M.5
Ressler, K.J.6
-
114
-
-
78349311969
-
Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans
-
PMID:20965453
-
Antal A, Chaieb L, Moliadze V, Monte-Silva K, Poreisz C, Thirugnanasambandam N, et al. Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain Stimul 2010; 3:230-7; PMID:20965453; http://dx.doi.org/10.1016/j.brs.2009.12.003.
-
(2010)
Brain Stimul
, vol.3
, pp. 230-237
-
-
Antal, A.1
Chaieb, L.2
Moliadze, V.3
Monte-Silva, K.4
Poreisz, C.5
Thirugnanasambandam, N.6
-
115
-
-
77951855933
-
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
-
PMID:20407211
-
Massa SM, Yang T, Xie Y, Shi J, Bilgen M, Joyce JN, et al. Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. J Clin Invest 2010; 120:1774-85; PMID:20407211; http://dx.doi.org/10. 1172/JCI41356.
-
(2010)
J Clin Invest
, vol.120
, pp. 1774-1785
-
-
Massa, S.M.1
Yang, T.2
Xie, Y.3
Shi, J.4
Bilgen, M.5
Joyce, J.N.6
-
116
-
-
79960343573
-
Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients
-
PMID:20860877
-
Laske C, StellosK, Hoffmann N, Stransky E, Straten G, Eschweiler GW, et al. Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients. Int J Neuropsychopharmacol 2011; 14:399-404; PMID:20860877; http://dx.doi.org/10.1017/S1461145710001008.
-
(2011)
Int J Neuropsychopharmacol
, vol.14
, pp. 399-404
-
-
Laske, C.1
Stellos, K.2
Hoffmann, N.3
Stransky, E.4
Straten, G.5
Eschweiler, G.W.6
-
117
-
-
77955519894
-
Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients
-
PMID:20714169
-
Dell'Osso L, Del Debbio A, Veltri A, Bianchi C, Roncaglia I, Carlini M, et al. Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients. Neuropsychobiology 2010; 62:207-12; PMID:20714169; http://dx.doi.org/10.1159/ 000319946.
-
(2010)
Neuropsychobiology
, vol.62
, pp. 207-212
-
-
Dell'Osso, L.1
Del Debbio, A.2
Veltri, A.3
Bianchi, C.4
Roncaglia, I.5
Carlini, M.6
-
118
-
-
0025993361
-
BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease
-
PMID:1742020
-
Phillips HS, Hains JM, Armanini M, Laramee GR, Johnson SA, Winslow JW. BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease. Neuron 1991; 7:695-702; PMID:1742020; http://dx.doi.org/10.1016/0896- 6273(91)90273-3.
-
(1991)
Neuron
, vol.7
, pp. 695-702
-
-
Phillips, H.S.1
Hains, J.M.2
Armanini, M.3
Laramee, G.R.4
Johnson, S.A.5
Winslow, J.W.6
-
119
-
-
62049083420
-
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
-
PMID:19198615
-
Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med 2009; 15:331-7; PMID:19198615; http://dx.doi.org/10.1038/nm.1912.
-
(2009)
Nat Med
, vol.15
, pp. 331-337
-
-
Nagahara, A.H.1
Merrill, D.A.2
Coppola, G.3
Tsukada, S.4
Schroeder, B.E.5
Shaked, G.M.6
-
120
-
-
0032408601
-
Therapeutic applications of implantable drug delivery systems
-
PMID:9920528
-
Dash AK, Cudworth GC, 2nd. Therapeutic applications of implantable drug delivery systems. J Pharmacol Toxicol Methods 1998; 40:1-12; PMID:9920528; http://dx.doi.org/10.1016/S1056-8719(98)00027-6.
-
(1998)
J Pharmacol Toxicol Methods
, vol.40
, pp. 1-12
-
-
Dash, A.K.1
Cudworth II, G.C.2
-
121
-
-
77955894067
-
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
-
PMID:20624852
-
Hua Y, Sahashi K, Hung G, Rigo F, Passini MA, Bennett CF, et al. Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes Dev 2010; 24:1634-44; PMID:20624852; http://dx.doi.org/ 10.1101/gad.1941310.
-
(2010)
Genes Dev
, vol.24
, pp. 1634-1644
-
-
Hua, Y.1
Sahashi, K.2
Hung, G.3
Rigo, F.4
Passini, M.A.5
Bennett, C.F.6
-
122
-
-
44849116327
-
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163
-
PMID:18287341
-
Hashizume R, Ozawa T, Gryaznov SM, Bollen AW, Lamborn KR, Frey WH, 2nd, et al. New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163. Neuro Oncol 2008; 10:112-20; PMID:18287341; http://dx.doi.org/10.1215/15228517-2007-052.
-
(2008)
Neuro Oncol
, vol.10
, pp. 112-120
-
-
Hashizume, R.1
Ozawa, T.2
Gryaznov, S.M.3
Bollen, A.W.4
Lamborn, K.R.5
Frey II, W.H.6
-
123
-
-
84859628864
-
Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
-
PMID:22500629
-
Michalon A, Sidorov M, Ballard TM, Ozmen L, Spooren W, Wettstein JG, et al. Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice. Neuron 2012; 74:49-56; PMID:22500629.
-
(2012)
Neuron
, vol.74
, pp. 49-56
-
-
Michalon, A.1
Sidorov, M.2
Ballard, T.M.3
Ozmen, L.4
Spooren, W.5
Wettstein, J.G.6
-
124
-
-
34447535345
-
Engineering targeted viral vectors for gene therapy
-
PMID:17607305
-
Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy. Nat Rev Genet 2007; 8:573-87; PMID:17607305; http://dx.doi.org/10. 1038/nrg2141.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 573-587
-
-
Waehler, R.1
Russell, S.J.2
Curiel, D.T.3
-
125
-
-
9244233812
-
Virosomes for antigen and DNA delivery
-
PMID:15560951
-
Daemen T, de Mare A, Bungener L, de Jonge J, Huckriede A, Wilschut J. Virosomes for antigen and DNA delivery. Adv Drug Deliv Rev 2005; 57:451-63; http://dx.doi.org/10.1016/j.addr.2004.09.005; PMID:15560951.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 451-463
-
-
Daemen, T.1
De Mare, A.2
Bungener, L.3
De Jonge, J.4
Huckriede, A.5
Wilschut, J.6
-
126
-
-
0032503029
-
Viral strategies of immune evasion
-
PMID:9535648
-
Ploegh HL. Viral strategies of immune evasion. Science 1998; 280:248-53; PMID:9535648; http://dx.doi.org/10.1126/science.280.5361.248.
-
(1998)
Science
, vol.280
, pp. 248-253
-
-
Ploegh, H.L.1
-
127
-
-
34548277482
-
Using attenuated Salmonella typhi as tumor targeting vector for MDR1 siRNA delivery
-
PMID:17374987
-
Jiang Z, Zhao P, Zhou Z, Liu J, Qin L, Wang H. Using attenuated Salmonella typhi as tumor targeting vector for MDR1 siRNA delivery. Cancer Biol Ther 2007; 6:555-60; PMID:17374987; http://dx.doi.org/10.4161/cbt.6.4.3850.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 555-560
-
-
Jiang, Z.1
Zhao, P.2
Zhou, Z.3
Liu, J.4
Qin, L.5
Wang, H.6
-
128
-
-
1342287828
-
DNA delivery to cells in culture using peptides
-
PMID:14707368
-
Zhang L, Ambulos N, Mixson AJ. DNA delivery to cells in culture using peptides. Methods Mol Biol 2004; 245:33-52; PMID:14707368.
-
(2004)
Methods Mol Biol
, vol.245
, pp. 33-52
-
-
Zhang, L.1
Ambulos, N.2
Mixson, A.J.3
-
129
-
-
0026535978
-
Dynamics of PhiX174 protein E-mediated lysis of Escherichia coli
-
PMID:1534215
-
Witte A, Wanner G, Sulzner M, Lubitz W. Dynamics of PhiX174 protein E-mediated lysis of Escherichia coli. Arch Microbiol 1992; 157:381-8; PMID:1534215; http://dx.doi.org/10.1007/BF00248685.
-
(1992)
Arch Microbiol
, vol.157
, pp. 381-388
-
-
Witte, A.1
Wanner, G.2
Sulzner, M.3
Lubitz, W.4
-
130
-
-
14744269876
-
Bacterial ghosts as novel efficient targeting vehicles for DNA delivery to the human monocyte-derived dendritic cells
-
PMID:15725957
-
Kudela P, Paukner S, Mayr UB, Cholujova D, Schwarczova Z, Sedlak J, et al. Bacterial ghosts as novel efficient targeting vehicles for DNA delivery to the human monocyte-derived dendritic cells. J Immunother 2005; 28:136-43; PMID:15725957; http://dx.doi.org/10.1097/01.cji.0000154246.89630.6f.
-
(2005)
J Immunother
, vol.28
, pp. 136-143
-
-
Kudela, P.1
Paukner, S.2
Mayr, U.B.3
Cholujova, D.4
Schwarczova, Z.5
Sedlak, J.6
-
131
-
-
0346735300
-
Bacterial ghosts as novel advanced drug delivery systems: Antiproliferative activity of loaded doxorubicin in human Caco-2 cells
-
PMID:14684272
-
Paukner S, Kohl G, Lubitz W. Bacterial ghosts as novel advanced drug delivery systems: antiproliferative activity of loaded doxorubicin in human Caco-2 cells. J Control Release 2004; 94:63-74; PMID:14684272; http://dx.doi.org/10.1016/j.jconrel.2003.09.010.
-
(2004)
J Control Release
, vol.94
, pp. 63-74
-
-
Paukner, S.1
Kohl, G.2
Lubitz, W.3
-
132
-
-
12744278653
-
DNA-loaded bacterial ghosts efficiently mediate reporter gene transfer and expression in macrophages
-
PMID:15668133
-
Paukner S, Kudela P, Kohl G, Schlapp T, Friedrichs S, Lubitz W. DNA-loaded bacterial ghosts efficiently mediate reporter gene transfer and expression in macrophages. Mol Ther 2005; 11:215-23; PMID:15668133; http://dx.doi.org/10.1016/j.ymthe.2004.09.024.
-
(2005)
Mol Ther
, vol.11
, pp. 215-223
-
-
Paukner, S.1
Kudela, P.2
Kohl, G.3
Schlapp, T.4
Friedrichs, S.5
Lubitz, W.6
-
133
-
-
77955474710
-
Applications of bacterial ghosts in biomedicine
-
PMID:20047041
-
Lubitz P, Mayr UB, Lubitz W. Applications of bacterial ghosts in biomedicine. Adv Exp Med Biol 2009; 655:159-70; PMID:20047041; http://dx.doi.org/10.1007/978-1-4419-1132-2-12.
-
(2009)
Adv Exp Med Biol
, vol.655
, pp. 159-170
-
-
Lubitz, P.1
Mayr, U.B.2
Lubitz, W.3
-
134
-
-
0036007293
-
Expression of HIF-1alpha by human macrophages: Implications for the use of macrophages in hypoxia-regulated cancer gene therapy
-
PMID:11793372
-
Burke B, Tang N, Corke KP, Tazzyman D, Ameri K, Wells M, et al. Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy. J Pathol 2002; 196:204-12; PMID:11793372; http://dx.doi.org/10.1002/path.1029.
-
(2002)
J Pathol
, vol.196
, pp. 204-212
-
-
Burke, B.1
Tang, N.2
Corke, K.P.3
Tazzyman, D.4
Ameri, K.5
Wells, M.6
-
135
-
-
0036744016
-
Macrophages in gene therapy: Cellular delivery vehicles and in vivo targets
-
PMID:12223508
-
Burke B, Sumner S, Maitland N, Lewis CE. Macrophages in gene therapy: cellular delivery vehicles and in vivo targets. J Leukoc Biol 2002; 72:417-28; PMID:12223508.
-
(2002)
J Leukoc Biol
, vol.72
, pp. 417-428
-
-
Burke, B.1
Sumner, S.2
Maitland, N.3
Lewis, C.E.4
-
136
-
-
68949102075
-
Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS
-
PMID:19535632
-
Dou H, Grotepas CB, McMillan JM, Destache CJ, Chaubal M, Werling J, et al. Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS. J Immunol 2009; 183:661-9; PMID:19535632; http://dx.doi.org/10.4049/jimmunol.0900274.
-
(2009)
J Immunol
, vol.183
, pp. 661-669
-
-
Dou, H.1
Grotepas, C.B.2
McMillan, J.M.3
Destache, C.J.4
Chaubal, M.5
Werling, J.6
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