Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 39, 2005, Pages 14080-14085

  Rashidian, Juliet ^a   Iyirhiaro, Grace ^a   Aleyasin, Hossein ^a   Rios, Mario ^a   Vincent, Inez ^b   Callaghan, Steven ^a   Bland, Ross J ^c   Slack, Ruth S ^a   During, Matthew J ^c,d   Park, David S ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WASHINGTON   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Hypoxia; Stroke

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 5; PROTEIN P35; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL ASSAY; CELL CYCLE; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; EXCITOTOXICITY; EXPERIMENTAL MODEL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NERVE CELL NECROSIS; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STROKE; TRANSGENIC MOUSE;

ANIMALS; CELL DEATH; CEREBROVASCULAR ACCIDENT; CYCLIN D1; HYPOXIA-ISCHEMIA, BRAIN; MICE; MICE, KNOCKOUT; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORYLATION; RATS; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION;

EID: 25444460165     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500099102     Document Type: Article

References (33)

1. Dirnagl, U., Iadecola, C. & Moskowitz, M. (1999) Trends Neurosci. 22, 391-397.
2. Ekholm, S. & Reed, S. (2000) Curr. Opin. Cell Biol. 12, 676-684.
3. Gold, M. & Rice, A. (1998) Nucleic Acids Res. 26, 3784-3788.
4. Dhavan, R. & Tsai, L. (2001) Nat. Rev. Mol. Cell. Biol. 2, 749-759.
5. Copani, A., Uberti, D., Sortino, M., Bruno, V., Nicoletti, F. & Memo, M. (2001) Trends Neurosci. 24, 25-31.
6. Timsit, S., Rivera, S., Ouaghi, P., Guischard, F., Tremblay, E., Ben-Ari, Y. & Khrestchatisky, M. (1999) Eur. J. Neurosci. 11, 263-278.
7. Katchanov, J., Harms, C., Gertz, K., Hauck, L., Waeber, C., Hirt, L., Priller, J., von Harsdorf, R., Bruck, W., Hortnagl, H., et al. (2001) J. Neurosci. 21, 5045-5053.
8. Osuga, H., Osuga, S., Wang, F., Fetni, R., Hogan, M., Slack, R., Hakim, A., Ikeda, J. & Park, D. (2000) Proc. Natl. Acad. Sci. USA 97, 10254-10259.
9. Wang, F., Corbett, D., Osuga, H., Osuga, S., Ikeda, J., Slack, R., Hogan, M., Hakim, A. & Park, D. (2002) J. Cereb. Blood Flow Metab. 22, 171-182.
10. Wang, J., Liu, S., Fu, Y., Wang, J. & Lu, Y. (2003) Nat. Neurosci. 6, 1039-1047.
11. De Azevedo, W., Jr., Mueller-Dieckmann, H., Schulze-Gahmen, U., Worland, P., Sausville, E. & Kim, S. (1996) Proc. Natl. Acad. Sci. USA 93, 2735-2740.
12. Smith, P., Crocker, S., Jackson-Lewis, V., Jordan-Sciutto, K., Hayley, S., Mount, M., O'Hare, M. J., Callaghan, S., Slack, R., Przedborski, S., et al. (2003) Proc. Natl. Acad. Sci. USA 100, 13650-13655.
13. Leclerc, S., Garnier, M., Hoessel, R., Marko, D., Bibb, J., Snyder, G., Greengard, P., Biernat, J., Wu, Y., Mandelkow, E., et al. (2001) J. Biol. Chem. 276, 251-260.
14. Park, D., Levine, B., Ferrari, G. & Greene, L. (1997) J. Neurosci. 17, 8975-8983.
15. van den Heuvel, S. & Harlow, E. (1993) Science 262, 2050-2054.
16. Gong, X., Tang, X., Wiedmann, M., Wang, X., Peng, J., Zheng, D., Blair, L., Marshall, J. & Mao, Z. (2003) Neuron 38, 33-46.
17. Zolotukhin, S., Potter, M., Zolotukhin, I., Sakai, Y., Loiler, S., Fraites, T., Jr., Chiodo, V., Phillipsberg, T., Muzyczka, N., Hauswirth, W., et al. (2002) Methods. 28, 158-167.
18. He, T., Zhou, S., da Costa, L., Yu, J., Kinzler, K. & Vogelstein, B. (1998) Proc. Natl. Acad. Sci. USA 95, 2509-2514.
19. Park, D., Morris, E., Bremner, R., Keramaris, E., Padmanabhan, J., Rosenbaum, M., Shelanski, M., Geller, H. & Greene, L. (2000) J. Neurosci. 20, 3104-3114.
20. Hallows, J., Chen, K., DePinho, R. & Vincent, I. (2003) J. Neurosci. 23, 10633-10644.
21. O'Hare, M., Hou, S., Morris, E., Cregan, S., Xu, Q., Slack, R. & Park, D. (2000) J. Biol. Chem. 275, 25358-25364.
22. Biernaskie, J. & Corbett, D. (2001) J. Neurosci. 21, 5272-5280.
23. Swanson, R., Morton, M., Tsao-Wu, G., Savalos, R., Davidson, C. & Sharp, F. (1990) J. Cereb. Blood Flow Metab. 10, 290-293.
24. Pines, J. (1993) Biochem. Soc. Trans. 21, 921-925.
25. Briones, T. & Therrien, B. (2000) Biol. Res. Nurs. 1, 276-286.
26. Connell-Crowley, L., Harper, J. & Goodrich, D. (1997) Mol. Biol. Cell 8, 287-301.
27. Morris, E. & Dyson, N. (2001) Adv. Cancer Res. 82, 1-54.
28. Liu, D. & Greene, L. (2001) Neuron 32, 425-438.
29. Giovanni, A., Keramaris, E., Morris, E., Hou, S., O'Hare, M., Dyson, N., Robertson, G., Slack, R. & Park, D. (2000) J. Biol. Chem. 275, 11553-11560.
30. MacManus, J., Jian, M., Preston, E., Rasquinha, I., Webster, J. & Zurakowski, B. (2003) J. Cereb. Blood Flow Metab. 23, 1020-1028.
31. Arundine, M. & Tymianski, M. (2003) Cell Calcium 34, 325-337.
32. Markgraf, C., Velayo, N., Johnson, M., McCarty, D., Medhi, S., Koehl, J., Chmielewski, P. & Linnik, M. (1998) Stroke 29, 152-158.
33. Murase, K., Kato, H. & Kogure, K. (1993) Neurosci. Lett. 149, 229-232.