-
1
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJC, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. 1997. Role of translocation in the activation and function of protein kinase B. J Biol Chem 272:31515-31524.
-
(1997)
J Biol Chem
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.C.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lucocq, J.M.9
Hemmings, B.A.10
-
2
-
-
0035733762
-
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
-
Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, Tsao MS, Shannon P, Bolon B, Ivy GO, Mak TW. 2001. Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nat Genet 29:396-403.
-
(2001)
Nat Genet
, vol.29
, pp. 396-403
-
-
Backman, S.A.1
Stambolic, V.2
Suzuki, A.3
Haight, J.4
Elia, A.5
Pretorius, J.6
Tsao, M.S.7
Shannon, P.8
Bolon, B.9
Ivy, G.O.10
Mak, T.W.11
-
3
-
-
0017184389
-
A rapid and sensitive method for the quantification of micrograms quantities of proteins utilizing the principle of protein dye binding
-
Bradford MM. 1976. A rapid and sensitive method for the quantification of micrograms quantities of proteins utilizing the principle of protein dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
5
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/ AKT pathway
-
Cantley LC, Neel BG. 1999. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/ AKT pathway. Proc Natl Acad Sci 96:4240-4245.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
7
-
-
15044339552
-
Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia
-
Choi JS, Park HJ, Kim HY, Kim SY, Lee JE, Choi YS, Chun MH, Chung JW, Lee MY. 2005. Phosphorylation of PTEN and Akt in astrocytes of the rat hippocampus following transient forebrain ischemia. Cell Tissue Res 319:359-366.
-
(2005)
Cell Tissue Res
, vol.319
, pp. 359-366
-
-
Choi, J.S.1
Park, H.J.2
Kim, H.Y.3
Kim, S.Y.4
Lee, J.E.5
Choi, Y.S.6
Chun, M.H.7
Chung, J.W.8
Lee, M.Y.9
-
8
-
-
33746731609
-
PTEN is recruited to specific microdomains of the plasma membrane during lactacystin-induced neuronal apoptosis
-
Choy MS, Bay BH, Cheng HC, Cheung NS. 2006. PTEN is recruited to specific microdomains of the plasma membrane during lactacystin-induced neuronal apoptosis. Neurosci Lett 405:120-125.
-
(2006)
Neurosci Lett
, vol.405
, pp. 120-125
-
-
Choy, M.S.1
Bay, B.H.2
Cheng, H.C.3
Cheung, N.S.4
-
10
-
-
7444264727
-
Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo
-
Fraser MM, Zhu XY, Kwon CH, Uhlmann EJ, Gutmann DH, Baker SJ. 2004. Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo. Cancer Res 64:7773-7779.
-
(2004)
Cancer Res
, vol.64
, pp. 7773-7779
-
-
Fraser, M.M.1
Zhu, X.Y.2
Kwon, C.H.3
Uhlmann, E.J.4
Gutmann, D.H.5
Baker, S.J.6
-
11
-
-
0041825308
-
PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis
-
Gary DS, Mattson MP. 2002. PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis. Neuromolecular Med 2:261-269.
-
(2002)
Neuromolecular Med
, vol.2
, pp. 261-269
-
-
Gary, D.S.1
Mattson, M.P.2
-
12
-
-
18844472952
-
Expression of the PTEN tumour suppressor protein during human development
-
Gimm O, Attie-Bitach T, Lees JA, Vekemans M, Eng C. 2000. Expression of the PTEN tumour suppressor protein during human development. Hum Mol Genet 9:1633-1639.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1633-1639
-
-
Gimm, O.1
Attie-Bitach, T.2
Lees, J.A.3
Vekemans, M.4
Eng, C.5
-
13
-
-
30444455577
-
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry
-
Groszer M, Erickson R, Scripture-Adams DD, Dougherty JD, Belle JH, Zack JA, Geschwind DH, Liu X, Kornblum HI, Wu H. 2006. PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proc Natl Acad Sci 103:111-116.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 111-116
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Dougherty, J.D.4
Belle, J.H.5
Zack, J.A.6
Geschwind, D.H.7
Liu, X.8
Kornblum, H.I.9
Wu, H.10
-
14
-
-
0035824396
-
Negative regulation of neural stem/ progenitor cell proliferation by the Pten tumor suppressor gene in vivo
-
Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, Kornblum HI, Liu X, Wu H. 2001. Negative regulation of neural stem/ progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science 294:2186-2189.
-
(2001)
Science
, vol.294
, pp. 2186-2189
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Lesche, R.4
Trumpp, A.5
Zack, J.A.6
Kornblum, H.I.7
Liu, X.8
Wu, H.9
-
15
-
-
0032583122
-
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways
-
Gu J, Tamura M, Yamada KM. 1998. Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J Cell Biol 143:1375-1383.
-
(1998)
J Cell Biol
, vol.143
, pp. 1375-1383
-
-
Gu, J.1
Tamura, M.2
Yamada, K.M.3
-
16
-
-
0036953551
-
Neuropeptides, food intake and body weight regulation: A hypothalamic focus
-
Hillebrand JJ, de Wied D, Adan RA. 2002. Neuropeptides, food intake and body weight regulation: a hypothalamic focus. Peptides 23:2283-2306.
-
(2002)
Peptides
, vol.23
, pp. 2283-2306
-
-
Hillebrand, J.J.1
de Wied, D.2
Adan, R.A.3
-
17
-
-
0028802890
-
Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats
-
Ito Y, Goto K, Kondo H. 1995. Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats. Mol Brain Res 34:149-153.
-
(1995)
Mol Brain Res
, vol.34
, pp. 149-153
-
-
Ito, Y.1
Goto, K.2
Kondo, H.3
-
18
-
-
30544449810
-
Control of dendritic arborization by the phosphoinositide-3′- kinase-Akt-mammalian target of rapamycin pathway
-
Jaworski J, Spangler S, Seeburg DP, Hoogenraad CC, Sheng M. 2005. Control of dendritic arborization by the phosphoinositide-3′- kinase-Akt-mammalian target of rapamycin pathway. J Neurosci 25:11300-11312.
-
(2005)
J Neurosci
, vol.25
, pp. 11300-11312
-
-
Jaworski, J.1
Spangler, S.2
Seeburg, D.P.3
Hoogenraad, C.C.4
Sheng, M.5
-
19
-
-
33644817011
-
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse
-
Ji SP, Cleemput JC, Jiang W, Liao MX, Li L, Wan Q, Backstrom JR, Zhang X. 2006. Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. Nat Med 12:324-329.
-
(2006)
Nat Med
, vol.12
, pp. 324-329
-
-
Ji, S.P.1
Cleemput, J.C.2
Jiang, W.3
Liao, M.X.4
Li, L.5
Wan, Q.6
Backstrom, J.R.7
Zhang, X.8
-
20
-
-
0037409877
-
Activation of Erk1/2 and Akt in astrocytes under ischemia
-
Jiang Z, Zhang Y, Chen X, Lam PY, Yang H, Xu Q, Hoi Yu AC. 2003. Activation of Erk1/2 and Akt in astrocytes under ischemia. Neurochem Res 28:831-837.
-
(2003)
Neurochem Res
, vol.28
, pp. 831-837
-
-
Jiang, Z.1
Zhang, Y.2
Chen, X.3
Lam, P.Y.4
Yang, H.5
Xu, Q.6
Hoi Yu, A.C.7
-
21
-
-
0036798144
-
Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis
-
Kabir J, Lobo M, Zachary I. 2002. Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis. Biochem J 367:145-155.
-
(2002)
Biochem J
, vol.367
, pp. 145-155
-
-
Kabir, J.1
Lobo, M.2
Zachary, I.3
-
22
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS. 1999. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100.
-
(1999)
Endocr Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
23
-
-
0032886308
-
Immunoreactive Akt, PI3-K and ERK protein kinase expression in ischemic rat brain
-
Kitagawa H, Warita H, Sasaki C, Zhang WR, Sakai K, Shiro Y, Mitsumoto Y, Mori T, Abe K. 1999. Immunoreactive Akt, PI3-K and ERK protein kinase expression in ischemic rat brain. Neurosci Lett 274:45-48.
-
(1999)
Neurosci Lett
, vol.274
, pp. 45-48
-
-
Kitagawa, H.1
Warita, H.2
Sasaki, C.3
Zhang, W.R.4
Sakai, K.5
Shiro, Y.6
Mitsumoto, Y.7
Mori, T.8
Abe, K.9
-
24
-
-
0242499482
-
Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-30-kinase/ protein kinase B (Akt) signal transduction pathway in glioblastomas
-
Knobbe CB, Reinfenberger G. 2003. Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-30-kinase/ protein kinase B (Akt) signal transduction pathway in glioblastomas. Brain Patholl 13:507-518.
-
(2003)
Brain Patholl
, vol.13
, pp. 507-518
-
-
Knobbe, C.B.1
Reinfenberger, G.2
-
25
-
-
65549094506
-
-
Kremer H, Nelen M, Schepens J, Hendrik W, Padberg G. 1999. PTEN transcription in mouse development. Am J Hum Genet(-Suppl):A134.
-
Kremer H, Nelen M, Schepens J, Hendrik W, Padberg G. 1999. PTEN transcription in mouse development. Am J Hum Genet(-Suppl):A134.
-
-
-
-
26
-
-
0035734381
-
Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
-
Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ. 2001. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat Genet 29:404-411.
-
(2001)
Nat Genet
, vol.29
, pp. 404-411
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Knoop, L.L.4
Tharp, R.5
Smeyne, R.J.6
Eberhart, C.G.7
Burger, P.C.8
Baker, S.J.9
-
27
-
-
0034652102
-
A role for nuclear PTEN in neuronal differentiation
-
Lachyankar MB, Sultana N, Schonhoff CM, Mitra P, Poluha W, Lambert S, Quesenberry PJ, Litofsky NS, Recht LD, Nabi R, Miller SJ, Ohta S, Neel BG, Ross AH. 2000. A role for nuclear PTEN in neuronal differentiation. J Neurosci 20:1404-1413.
-
(2000)
J Neurosci
, vol.20
, pp. 1404-1413
-
-
Lachyankar, M.B.1
Sultana, N.2
Schonhoff, C.M.3
Mitra, P.4
Poluha, W.5
Lambert, S.6
Quesenberry, P.J.7
Litofsky, N.S.8
Recht, L.D.9
Nabi, R.10
Miller, S.J.11
Ohta, S.12
Neel, B.G.13
Ross, A.H.14
-
28
-
-
1342302121
-
Cilostazol prevents focal cerebral ischemic injury by enhancing casein kinase 2 phosphorylation and suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation in rats
-
Lee JH, Kim KY, Lee YK, Park SY, Kim CD, Lee WS, Rhim BY, Hong KW. 2003. Cilostazol prevents focal cerebral ischemic injury by enhancing casein kinase 2 phosphorylation and suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation in rats. J Pharmacol Exp Ther 308:896-903.
-
(2003)
J Pharmacol Exp Ther
, vol.308
, pp. 896-903
-
-
Lee, J.H.1
Kim, K.Y.2
Lee, Y.K.3
Park, S.Y.4
Kim, C.D.5
Lee, W.S.6
Rhim, B.Y.7
Hong, K.W.8
-
29
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
-
Li DM, Sun H. 1997. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β. Cancer Res 57:2124-2129.
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
30
-
-
0032431028
-
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
-
Li DM, Sun H. 1998. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc. Natl Acad. Sci. USA 95:15406-15411.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 15406-15411
-
-
Li, D.M.1
Sun, H.2
-
31
-
-
0037423066
-
Cooperative expression of survival p-ERK and p-Akt signals in rat brain neurons after transient MCAO
-
Li F, Omori N, Jin G, Wang SJ, Sato K, Nagano I, Shoji M, Abe K. 2003a. Cooperative expression of survival p-ERK and p-Akt signals in rat brain neurons after transient MCAO. Brain Res 962:21-26.
-
(2003)
Brain Res
, vol.962
, pp. 21-26
-
-
Li, F.1
Omori, N.2
Jin, G.3
Wang, S.J.4
Sato, K.5
Nagano, I.6
Shoji, M.7
Abe, K.8
-
32
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. 1997. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275:1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
33
-
-
0345863401
-
Profiling of genes expressed by PTEN haploinsufficient neural precursor cells
-
Li L, He F, Litofsky NS, Recht LD, Ross AH. 2003b. Profiling of genes expressed by PTEN haploinsufficient neural precursor cells. Mol Cell Neurosci 24:1051-1061.
-
(2003)
Mol Cell Neurosci
, vol.24
, pp. 1051-1061
-
-
Li, L.1
He, F.2
Litofsky, N.S.3
Recht, L.D.4
Ross, A.H.5
-
34
-
-
0037215682
-
PTEN regulation of neural development and CNS stem cells
-
Li L, Liu F, Ross AH. 2003c. PTEN regulation of neural development and CNS stem cells. J Cell Biochem 88:24-28.
-
(2003)
J Cell Biochem
, vol.88
, pp. 24-28
-
-
Li, L.1
Liu, F.2
Ross, A.H.3
-
35
-
-
0036279763
-
PTEN in neural precursor cells: Regulation of migration, apoptosis, and proliferation
-
Li L, Liu FH, Salmonsen RA, Turner TK, Litofsky NS, Cristofano AD, Pandolfi PP, Jones SN, Recht LD, Ross AH. 2002. PTEN in neural precursor cells: regulation of migration, apoptosis, and proliferation. Mol Cell Neurosci 20:21-29.
-
(2002)
Mol Cell Neurosci
, vol.20
, pp. 21-29
-
-
Li, L.1
Liu, F.H.2
Salmonsen, R.A.3
Turner, T.K.4
Litofsky, N.S.5
Cristofano, A.D.6
Pandolfi, P.P.7
Jones, S.N.8
Recht, L.D.9
Ross, A.H.10
-
36
-
-
0032967046
-
Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development
-
Luukko K, Ylikorkala A, Tiainen M, Makela TP. 1999. Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development. Mech Dev 83:187-190.
-
(1999)
Mech Dev
, vol.83
, pp. 187-190
-
-
Luukko, K.1
Ylikorkala, A.2
Tiainen, M.3
Makela, T.P.4
-
37
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:13375-13378.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
38
-
-
0032904432
-
PTEN: A tumour suppressor that functions as a phospholipid phosphatase
-
Maehama T, Dixon JE. 1999. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol 9:125-128.
-
(1999)
Trends Cell Biol
, vol.9
, pp. 125-128
-
-
Maehama, T.1
Dixon, J.E.2
-
39
-
-
0034912744
-
PTEN and myotubularin: Novel phosphoinositide phosphatases
-
Maehama T, Taylor GS, Dixon JE. 2001. PTEN and myotubularin: novel phosphoinositide phosphatases. Rev Biochem 70:247-279.
-
(2001)
Rev Biochem
, vol.70
, pp. 247-279
-
-
Maehama, T.1
Taylor, G.S.2
Dixon, J.E.3
-
40
-
-
0036637660
-
PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum
-
Marino S, Krimpenfort P, Leung C, van der Korput HA, Trapman J, Camenisch I, Berns A, Brandner S. 2002. PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development 129:3513-3522.
-
(2002)
Development
, vol.129
, pp. 3513-3522
-
-
Marino, S.1
Krimpenfort, P.2
Leung, C.3
van der Korput, H.A.4
Trapman, J.5
Camenisch, I.6
Berns, A.7
Brandner, S.8
-
41
-
-
0030727172
-
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase B
-
Meier R, Alessi DR, Cron P, Andjelkovic M, Hemmings BA. 1997. Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase B. J Biol Chem 272:30491-30497.
-
(1997)
J Biol Chem
, vol.272
, pp. 30491-30497
-
-
Meier, R.1
Alessi, D.R.2
Cron, P.3
Andjelkovic, M.4
Hemmings, B.A.5
-
42
-
-
1542723390
-
Inhibition of neuronal phenotppe by PTEN in PC12 cells
-
Musatov S, Roberts J, Brooks AI, Pena J, Betchen S, Pfaff DW, Kaplitt MG. 2004. Inhibition of neuronal phenotppe by PTEN in PC12 cells. Neuroscience 101:3627-3631.
-
(2004)
Neuroscience
, vol.101
, pp. 3627-3631
-
-
Musatov, S.1
Roberts, J.2
Brooks, A.I.3
Pena, J.4
Betchen, S.5
Pfaff, D.W.6
Kaplitt, M.G.7
-
43
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
-
Myers MP, Pass I, Batty IH, Van der Kaay J, Stolarov JP, Hemmings BA, Wigler MH, Downes CP, Tonks NK. 1998. The lipid phosphatase activity of PTEN is critical for its tumor suppressor function. Proc Natl Acad Sci USA 95:13513-13518.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
Wigler, M.H.7
Downes, C.P.8
Tonks, N.K.9
-
44
-
-
0032525260
-
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
-
Namura S, Zhu J, Fink K, Endres M, Srinivasan A, Tomaselli KJ, Yuan J, Moskowitz MA. 1998. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci 18:3659-3668.
-
(1998)
J Neurosci
, vol.18
, pp. 3659-3668
-
-
Namura, S.1
Zhu, J.2
Fink, K.3
Endres, M.4
Srinivasan, A.5
Tomaselli, K.J.6
Yuan, J.7
Moskowitz, M.A.8
-
45
-
-
33745030531
-
Essential role of Pten in body size determination and pancreatic β-cell homeostasis in vivo
-
Nguyen KT, Tajmir P, Lin CH, Liadis N, Zhu XD, Eweida M, Tolasa-Karaman G, Cai F, Wang R, Kitamura T, Belsham DD, Wheeler MB, Suzuki A, Mak TW, Woo M. 2006. Essential role of Pten in body size determination and pancreatic β-cell homeostasis in vivo. Mol Cell Biol 26:4511-4518.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4511-4518
-
-
Nguyen, K.T.1
Tajmir, P.2
Lin, C.H.3
Liadis, N.4
Zhu, X.D.5
Eweida, M.6
Tolasa-Karaman, G.7
Cai, F.8
Wang, R.9
Kitamura, T.10
Belsham, D.D.11
Wheeler, M.B.12
Suzuki, A.13
Mak, T.W.14
Woo, M.15
-
46
-
-
33745747676
-
A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic β-cells
-
Ning K, Miller LC, Laidlaw HA, Burgess LA, Perera NM, Downes CP, Leslie NR, Ashford ML. 2006. A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic β-cells. EMBO J 25:2377-2387.
-
(2006)
EMBO J
, vol.25
, pp. 2377-2387
-
-
Ning, K.1
Miller, L.C.2
Laidlaw, H.A.3
Burgess, L.A.4
Perera, N.M.5
Downes, C.P.6
Leslie, N.R.7
Ashford, M.L.8
-
47
-
-
11144356390
-
Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN
-
Ning K, Pei L, Liao MX, Liu BS, Zhang YZ, Jiang W, Mielke JG, Li L, Chen YH, El-Hayek YH, Fehlings MG, Zhang X, Liu F, Eubanks J, Wan Q. 2004. Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. J Neurosci 24:4052-4060.
-
(2004)
J Neurosci
, vol.24
, pp. 4052-4060
-
-
Ning, K.1
Pei, L.2
Liao, M.X.3
Liu, B.S.4
Zhang, Y.Z.5
Jiang, W.6
Mielke, J.G.7
Li, L.8
Chen, Y.H.9
El-Hayek, Y.H.10
Fehlings, M.G.11
Zhang, X.12
Liu, F.13
Eubanks, J.14
Wan, Q.15
-
48
-
-
0035194849
-
Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice
-
Noshita N, Lewen A, Sugawara T, Chan PH. 2001. Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab 21:1442-1450.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 1442-1450
-
-
Noshita, N.1
Lewen, A.2
Sugawara, T.3
Chan, P.H.4
-
49
-
-
33746872876
-
Modulation of the PI 3-kinase-Akt signalling pathway by IGF-I and PTEN regulates the differentiation of neural stem/precursor cells
-
Otaegi G, Yusta-Boyo MJ, Vergaño-Vera E, Méndez-Gómez HR, Carrera AC, Abad JL, González M, de la Rosa EJ, Vicario-Abejón C, Pablo F. 2006. Modulation of the PI 3-kinase-Akt signalling pathway by IGF-I and PTEN regulates the differentiation of neural stem/precursor cells. J Cell Sci 119:2739-2748.
-
(2006)
J Cell Sci
, vol.119
, pp. 2739-2748
-
-
Otaegi, G.1
Yusta-Boyo, M.J.2
Vergaño-Vera, E.3
Méndez-Gómez, H.R.4
Carrera, A.C.5
Abad, J.L.6
González, M.7
de la Rosa, E.J.8
Vicario-Abejón, C.9
Pablo, F.10
-
51
-
-
0034724199
-
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation
-
Pekarsky Y, Koval A, Hallas C, Bichi R, Tresini M, Malstrom S, Russo G, Tsichlis P, Croce CM. 2000. Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc Natl Acad Sci USA 97:3028-3033.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3028-3033
-
-
Pekarsky, Y.1
Koval, A.2
Hallas, C.3
Bichi, R.4
Tresini, M.5
Malstrom, S.6
Russo, G.7
Tsichlis, P.8
Croce, C.M.9
-
52
-
-
4344683876
-
Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development
-
Perandones C, Costanzo RV, Kowaljow V, Pivetta OH, Carminatti H, Radrizzani M. 2004. Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development. Mol Brain Res 128:8-19.
-
(2004)
Mol Brain Res
, vol.128
, pp. 8-19
-
-
Perandones, C.1
Costanzo, R.V.2
Kowaljow, V.3
Pivetta, O.H.4
Carminatti, H.5
Radrizzani, M.6
-
53
-
-
2342458960
-
Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome
-
Pilarski R, Eng C. 2004. Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome. J Med Genet 41: 323-326.
-
(2004)
J Med Genet
, vol.41
, pp. 323-326
-
-
Pilarski, R.1
Eng, C.2
-
54
-
-
0032546462
-
Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain
-
Shin BC, Suzuki M, Inukai K, Anai M, Asano T, Takata K. 1998. Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain. Biochem Biophys Res Commun 246:313-319.
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 313-319
-
-
Shin, B.C.1
Suzuki, M.2
Inukai, K.3
Anai, M.4
Asano, T.5
Takata, K.6
-
55
-
-
0035835824
-
PTEN: Life as a tumor suppressor
-
Simpson L, Parsons R. 2001. PTEN: life as a tumor suppressor. Exp Cell Res 264:29-41.
-
(2001)
Exp Cell Res
, vol.264
, pp. 29-41
-
-
Simpson, L.1
Parsons, R.2
-
56
-
-
0021244677
-
Models for studying long-term recovery following forebrain ischemia in the rat. A 2-vessel occlusion model
-
Smith ML, Bendek G, Dahlgren N, Rosen I, Wieloch T, Siesjo BK. 1984. Models for studying long-term recovery following forebrain ischemia in the rat. A 2-vessel occlusion model. Acta Neurol Scand 69:385-401.
-
(1984)
Acta Neurol Scand
, vol.69
, pp. 385-401
-
-
Smith, M.L.1
Bendek, G.2
Dahlgren, N.3
Rosen, I.4
Wieloch, T.5
Siesjo, B.K.6
-
57
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, Sasaki T, Ruland J, Penninger JM, Siderovski DP, Mak TW. 1998. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95:29-39.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
de la Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
58
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WKA, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DHF, Tavtigian SV. 1997. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 15:356-362.
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.F.14
Tavtigian, S.V.15
-
59
-
-
4344698040
-
PTENless means more
-
Stiles B, Groszer M, Wang SI, Jiao J, Wu H. 2004. PTENless means more. Dev Biol 273:175-184.
-
(2004)
Dev Biol
, vol.273
, pp. 175-184
-
-
Stiles, B.1
Groszer, M.2
Wang, S.I.3
Jiao, J.4
Wu, H.5
-
60
-
-
0033573532
-
Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior
-
Stratford TR, Kelley AE. 1999. Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior. J Neurosci 19:11040-11048.
-
(1999)
J Neurosci
, vol.19
, pp. 11040-11048
-
-
Stratford, T.R.1
Kelley, A.E.2
-
61
-
-
21544453866
-
PTEN-mediated Akt activation in human neocortex during prenatal development
-
Tanriover G, Demir N, Pestereli E, Demir R, Kayisli UA. 2005. PTEN-mediated Akt activation in human neocortex during prenatal development. Histochem Cell Biol 123:393-406.
-
(2005)
Histochem Cell Biol
, vol.123
, pp. 393-406
-
-
Tanriover, G.1
Demir, N.2
Pestereli, E.3
Demir, R.4
Kayisli, U.A.5
-
62
-
-
0031888098
-
β-Catenin: A key mediator of Wnt signaling
-
Willert K, Nusse R. 1998. β-Catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev 8:95-102.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 95-102
-
-
Willert, K.1
Nusse, R.2
-
63
-
-
0034921007
-
Tumor suppressor PTEN: Modulator of cell signaling, growth, migration and apoptosis
-
Yamada KM, Araki M. 2001. Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. J Cell Sci 114:2375-2382.
-
(2001)
J Cell Sci
, vol.114
, pp. 2375-2382
-
-
Yamada, K.M.1
Araki, M.2
-
64
-
-
0034641936
-
Apoptosis in the nervous system
-
Yuan JY, Yankner BA. 2000. Apoptosis in the nervous system. Nature 407:802-809.
-
(2000)
Nature
, vol.407
, pp. 802-809
-
-
Yuan, J.Y.1
Yankner, B.A.2
-
65
-
-
23844432216
-
PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization
-
Yue Q, Groszer M, Gil JS, Berk AJ, Messing A, Wu H, Liu X. 2005. PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization. Development 132:3281-3291.
-
(2005)
Development
, vol.132
, pp. 3281-3291
-
-
Yue, Q.1
Groszer, M.2
Gil, J.S.3
Berk, A.J.4
Messing, A.5
Wu, H.6
Liu, X.7
|