miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia

Neurobiology of Disease

Volumn 38, Issue 1, 2010, Pages 17-26

  Yin, Ke Jie ^a   Deng, Zhen ^a   Huang, Huarong ^a   Hamblin, Milton ^a   Xie, Changqing ^a   Zhang, Jifeng ^a   Chen, Y Eugene ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Apoptosis; bcl 2; bcl w; Cerebral cortex; Cerebral ischemia; MicroRNAs; Oxygen glucose deprivation

Indexed keywords

GLUCOSE; MICRORNA; MICRORNA 497; OXYGEN; PROTEIN BCL 2; PROTEIN BCL W; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION; BRAIN INJURY; CELL LOSS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; GENE FUNCTION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REGULATORY MECHANISM; TRANSIENT ISCHEMIC ATTACK;

3' UNTRANSLATED REGIONS; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BINDING SITES; BRAIN; BRAIN ISCHEMIA; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; NERVE DEGENERATION; PROTEINS; PROTO-ONCOGENE PROTEINS;

EID: 77549088509     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.12.021     Document Type: Article

References (45)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
2. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 136 (2009) 215-233
3. Bartel D.P., and Chen C.Z. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5 (2004) 396-400
4. Care A., et al. MicroRNA-133 controls cardiac hypertrophy. Nat. Med. 13 (2007) 613-618
5. Chen J., et al. Suppression of endogenous bcl-2 expression by antisense treatment exacerbates ischemic neuronal death. J. Cereb. Blood Flow. Metab. 20 (2000) 1033-1039
6. Cimmino A., et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 13944-13949
7. Dharap A., et al. Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome. J. Cereb. Blood Flow Metab. 29 (2009) 675-687
8. Frankel L.B., et al. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 283 (2008) 1026-1033
9. Goldstein L.B., et al. Primary prevention of ischemic stroke: a statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke 32 (2001) 280-299
10. Hata R., et al. Targeted disruption of the bcl-2 gene in mice exacerbates focal ischemic brain injury. Metab. Brain Dis. 14 (1999) 117-124
11. Hayashita Y., et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65 (2005) 9628-9632
12. Hebert S.S., et al. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 6415-6420
13. Jeyaseelan K., et al. MicroRNAs as therapeutic targets in human diseases. Expert. Opin. Ther. Targets. 11 (2007) 1119-1129
14. Jovanovic M., and Hengartner M.O. miRNAs and apoptosis: RNAs to die for. Oncogene 25 (2006) 6176-6187
15. Kalache A., and Aboderin I. Stroke: the global burden. Health Policy Plan. 10 (1995) 1-21
16. Ketting R.F., et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15 (2001) 2654-2659
17. Kim V.N. MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 6 (2005) 376-385
18. Kim J., et al. A MicroRNA feedback circuit in midbrain dopamine neurons. Science 317 (2007) 1220-1224
19. Kosik K.S. The neuronal microRNA system. Nat. Rev. Neurosci. 7 (2006) 911-920
20. Krutzfeldt J., and Stoffel M. MicroRNAs: a new class of regulatory genes affecting metabolism. Cell Metab. 4 (2006) 9-12
21. Kuhn D.E., et al. Experimental validation of miRNA targets. Methods 44 (2008) 47-54
22. Lee Y., et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23 (2004) 4051-4060
23. Linnik M.D., et al. Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke 26 (1995) 1670-1674 discussion 1675
24. Love S. Apoptosis and brain ischaemia. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 267-282
25. Martinou J.C., et al. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 13 (1994) 1017-1030
26. Meng F., et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133 (2007) 647-658
27. Mott J.L., et al. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26 (2007) 6133-6140
28. Paxinos G., et al. Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J. Neurosci. Methods 13 (1985) 139-143
29. Schellinger P.D., et al. An update on thrombolytic therapy for acute stroke. Curr. Opin. Neurol. 17 (2004) 69-77
30. Schickel R., et al. MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death. Oncogene 27 (2008) 5959-5974
31. Stapf C., and Mohr J.P. Ischemic stroke therapy. Annu. Rev. Med. 53 (2002) 453-475
32. Sullivan C.S., and Ganem D. MicroRNAs and viral infection. Mol. Cell 20 (2005) 3-7
33. Sun Y., et al. Adeno-associated virus-mediated delivery of BCL-w gene improves outcome after transient focal cerebral ischemia. Gene Ther. 10 (2003) 115-122
34. Swanson R.A., et al. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10 (1990) 290-293
35. Vemuganti R., et al. Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke 35 (2004) 179-184
36. Webster K.A., et al. Redox stress and the contributions of BH3-only proteins to infarction. Antioxid. Redox. Signal. 8 (2006) 1667-1676
37. Wiemer E.A. The role of microRNAs in cancer: no small matter. Eur. J. Cancer 43 (2007) 1529-1544
38. Wienholds E., and Plasterk R.H. MicroRNA function in animal development. FEBS Lett. 579 (2005) 5911-5922
39. Yang G.Y., et al. Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury. Brain Res. 751 (1997) 181-188
40. Yin K.J., et al. ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells. Stroke 33 (2002) 2471-2477
41. Yin K.J., et al. Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells. J. Neurosci. 22 (2002) 9764-9770
42. Yin K.J., et al. Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism. J. Neurosci. 26 (2006) 10939-10948
43. Yin K.J., et al. Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death. J. Neurosci. 26 (2006) 2290-2299
44. Youle R.J., and Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 9 (2008) 47-59
45. Yuan J. Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke. Apoptosis 14 (2009) 469-477