MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

Nature Neuroscience

Volumn 12, Issue 4, 2009, Pages 399-408

  Cheng, Li Chun ^a   Pastrana, Erika ^a   Tavazoie, Masoud ^a   Doetsch, Fiona ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TESTIS DETERMINING FACTOR;

ARTICLE; BRAIN NERVE CELL; CELL LINEAGE; DEFENSE MECHANISM; IN SITU HYBRIDIZATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; STEM CELL; SUBVENTRICULAR ZONE;

ADULT STEM CELLS; ANIMALS; BRAIN; BROMODEOXYURIDINE; C-REACTIVE PROTEIN; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTARABINE; EMBRYO, MAMMALIAN; FLOW CYTOMETRY; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEINS; IMMUNOSUPPRESSIVE AGENTS; KI-67 ANTIGEN; LATERAL VENTRICLES; MICE; MICRORNAS; MICROTUBULE-ASSOCIATED PROTEINS; NERVE TISSUE PROTEINS; NEUROGENESIS; NEUROPEPTIDES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; STEM CELL NICHE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC; TUBULIN;

EID: 63649138643     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn.2294     Document Type: Article

References (42)

1. Doetsch, F., Caille, I., Lim, D.A., Garcia-Verdugo, J.M. & Alvarez-Buylla, A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97, 703-716 (1999).
2. Menn, B. et al. Origin of oligodendrocytes in the subventricular zone of the adult brain. J. Neurosci. 26, 7907-7918 (2006).
3. Lachapelle, F., Avellana-Adalid, V., Nait-Oumesmar, B. & Baron-Van Evercooren, A. Fibroblast growth factor-2 (FGF-2) and platelet-derived growth factor AB (PDGF AB) promote adult SVZ-derived oligodendrogenesis in vivo. Mol. Cell. Neurosci. 20, 390-403 (2002).
4. Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism and function. Cell 116, 281-297 (2004).
5. Stefani, G. & Slack, F.J. Small non-coding RNAs in animal development. Nat. Rev. Mol. Cell Biol. 9, 219-230 (2008).
6. Flynt, A.S. & Lai, E.C. Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat. Rev. Genet. 9, 831-842 (2008).
7. Lagos-Quintana, M. et al. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12, 735-739 (2002).
8. Lim, L.P. et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773 (2005).
9. Conaco, C., Otto, S., Han, J.J. & Mandel, G. Reciprocal actions of RESTand a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. USA 103, 2422-2427 (2006).
10. Krichevsky, A.M., Sonntag, K.C., Isacson, O. & Kosik, K.S. Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864 (2006).
11. Makeyev, E.V., Zhang, J., Carrasco, M.A. & Maniatis, T. The microRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 27, 435-448 (2007).
12. Visvanathan, J., Lee, S., Lee, B., Lee, J.W. & Lee, S.K. The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749 (2007).
13. Cao, X., Pfaff, S.L. & Gage, F.H. A functional study of miR-124 in the developing neural tube. Genes Dev. 21, 531-536 (2007).
14. Noctor, S.C., Flint, A.C.,Weissman, T.A., Dammerman, R.S. & Kriegstein, A.R. Neurons derived from radial glial cells establish radial units in neocortex. Nature 409, 714-720 (2001).
15. Haubensak, W., Attardo, A., Denk, W. & Huttner, W.B. Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis. Proc. Natl. Acad. Sci. USA 101, 3196-3201 (2004).
16. Pastrana, E., Cheng, L.-C. & Doetsch, F. Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny. Proc. Natl. Acad. Sci. USA (in press).
17. Doetsch, F., Petreanu, L., Caille, I., Garcia-Verdugo, J.M. & Alvarez-Buylla, A. EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36, 1021-1034 (2002).
18. Lim, D.A. & Alvarez-Buylla, A. Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis. Proc. Natl. Acad. Sci. USA 96, 7526-7531 (1999).
19. Malatesta, P., Hartfuss, E. & Gotz, M. Isolation of radial glial cells by fluorescentactivated cell sorting reveals a neuronal lineage. Development 127, 5253-5263 (2000).
20. Meister, G., Landthaler, M., Dorsett, Y. & Tuschl, T. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 10, 544-550 (2004).
21. Hutvagner, G., Simard, M.J., Mello, C.C. & Zamore, P.D. Sequence-specific inhibition of small RNA function. PLoS Biol. 2, E98 (2004).
22. Davidson, T.J. et al. Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation. J. Neurosci. 24, 10040-10046 (2004).
23. Sempere, L.F. et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13 (2004).
24. Doetsch, F., Garcia-Verdugo, J.M. & Alvarez-Buylla, A. Regeneration of a germinal layer in the adult mammalian brain. Proc. Natl. Acad. Sci. USA 96, 11619-11624 (1999).
25. Lewis, B.P., Shih, I.H., Jones-Rhoades, M.W., Bartel, D.P. & Burge, C.B. Prediction of mammalian microRNA targets. Cell 115, 787-798 (2003).
26. Zhao, Y., Samal, E. & Srivastava, D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436, 214-220 (2005).
27. Chen, C.Z., Li, L., Lodish, H.F. & Bartel, D.P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-86 (2004).
28. Smirnova, L. et al. Regulation ofmiRNA expression during neural cell specification. Eur. J. Neurosci. 21, 1469-1477 (2005).
29. Panganiban, G. & Rubenstein, J.L. Developmental functions of the Distal-less/Dlx homeobox genes. Development 129, 4371-4386 (2002).
30. Nyfeler, Y. et al. Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal. EMBO J. 24, 3504-3515 (2005).
31. Finzsch, M., Stolt, C.C., Lommes, P. & Wegner, M. Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor a expression. Development 135, 637-646 (2008).
32. Stolt, C.C. et al. The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 17, 1677-1689 (2003).
33. Nowak, J.A., Polak, L., Pasolli, H.A. & Fuchs, E. Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell. 3, 33-43 (2008).
34. Bastide, P. et al. Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J. Cell Biol. 178, 635-648 (2007).
35. Vidal, V.P. et al. Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr. Biol. 15, 1340-1351 (2005).
36. Krichevsky, A.M., King, K.S., Donahue, C.P., Khrapko, K. & Kosik, K.S. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281 (2003).
37. Bartel, D.P. & Chen, C.Z. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5, 396-400 (2004).
38. Ballas, N., Grunseich, C., Lu, D.D., Speh, J.C. & Mandel, G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121, 645-657 (2005).
39. Singh, S.K., Kagalwala, M.N., Parker-Thornburg, J., Adams, H. & Majumder, S. REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 453, 223-227 (2008).
40. Choi, P.S. et al. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron 57, 41-55 (2008).
41. Silber, J. et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 6, 14 (2008).
42. Lim, D.A. et al. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28, 713-726 (2000).