-
1
-
-
0033808244
-
Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women
-
Matthan NR, Raeini-Sarjaz M, Lichtenstein AH, Ausman LM, Jones PJ. Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women. Lipids 2000;35:1037-44.
-
(2000)
Lipids
, vol.35
, pp. 1037-1044
-
-
Matthan, N.R.1
Raeini-Sarjaz, M.2
Lichtenstein, A.H.3
Ausman, L.M.4
Jones, P.J.5
-
2
-
-
0020648725
-
Sterol structure and membrane function
-
Bloch KE. Sterol structure and membrane function. CRC Crit Rev Biochem 1983;14:47-92.
-
(1983)
CRC Crit Rev Biochem
, vol.14
, pp. 47-92
-
-
Bloch, K.E.1
-
3
-
-
0023737126
-
Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans
-
Kempen HJ, Glatz JF, Gevers Leuven JA, Van Der Voort HA, Katan MB. Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res 1988;29:1149-55.
-
(1988)
J Lipid Res
, vol.29
, pp. 1149-1155
-
-
Kempen, H.J.1
Glatz, J.F.2
Gevers Leuven, J.A.3
Van Der Voort, H.A.4
Katan, M.B.5
-
4
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
DOI 10.1146/annurev.biochem.72.121801.161712
-
Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem 2003;72:137-74. (Pubitemid 36930444)
-
(2003)
Annual Review of Biochemistry
, vol.72
, pp. 137-174
-
-
Russell, D.W.1
-
5
-
-
0032769064
-
27-Hydroxycholesterol: Production rates in normal human subjects
-
Duane WC, Javitt NB. 27-hydroxycholesterol: production rates in normal human subjects. J Lipid Res 1999;40:1194-9. (Pubitemid 29328522)
-
(1999)
Journal of Lipid Research
, vol.40
, Issue.7
, pp. 1194-1199
-
-
Duane, W.C.1
Javitt, N.B.2
-
7
-
-
0035430622
-
Essential role for cholesterol in synaptic plasticity and neuronal degeneration
-
Koudinov AR, Koudinova NV. Essential role for cholesterol in synaptic plasticity and neuronal degeneration. FASEB J 2001;15:1858-60.
-
(2001)
FASEB J
, vol.15
, pp. 1858-1860
-
-
Koudinov, A.R.1
Koudinova, N.V.2
-
10
-
-
0037710127
-
Cholesterol homeostasis and function in neurons of the central nervous system
-
Pfrieger FW. Cholesterol homeostasis and function in neurons of the central nervous system. Cell Mol Life Sci 2003;60:1158-71. (Pubitemid 36791918)
-
(2003)
Cellular and Molecular Life Sciences
, vol.60
, Issue.6
, pp. 1158-1171
-
-
Pfrieger, F.W.1
-
11
-
-
79960459422
-
Cholesterol metabolism in neurons and astrocytes
-
Pfrieger FW, Ungerer N. Cholesterol metabolism in neurons and astrocytes. Prog Lipid Res 2011;50:357-71.
-
(2011)
Prog Lipid Res
, vol.50
, pp. 357-371
-
-
Pfrieger, F.W.1
Ungerer, N.2
-
12
-
-
55849118128
-
Apolipoprotein e and cholesterol in aging and disease in the brain
-
de Chaves EP, Narayanaswami V. Apolipoprotein E and cholesterol in aging and disease in the brain. Future Lipidol 2008;3:505-30.
-
(2008)
Future Lipidol
, vol.3
, pp. 505-530
-
-
De Chaves, E.P.1
Narayanaswami, V.2
-
13
-
-
67349270965
-
Apolipoprotein e and its receptors in Alzheimer's disease: Pathways, pathogenesis and therapy
-
Bu G. Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy. Nat Rev Neurosci 2009;10:333-44.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 333-344
-
-
Bu, G.1
-
14
-
-
80051471752
-
Pathways of cholesterol oxidation via non-enzymatic mechanisms
-
Iuliano L. Pathways of cholesterol oxidation via non-enzymatic mechanisms. Chem Phys Lipids 2011;164:457-68.
-
(2011)
Chem Phys Lipids
, vol.164
, pp. 457-468
-
-
Iuliano, L.1
-
15
-
-
0023243055
-
Cholesterol autooxidation
-
Smith LL. Cholesterol autooxidation. Chem Phys Lipids 1987;44:87-125.
-
(1987)
Chem Phys Lipids
, vol.44
, pp. 87-125
-
-
Smith, L.L.1
-
16
-
-
0034672672
-
Oxysterol biosynthetic enzymes
-
Russel DW. Oxysterol biosynthetic enzymes. Biochem Biophys Acta 2000;1529:126-35.
-
(2000)
Biochem Biophys Acta
, vol.1529
, pp. 126-135
-
-
Russel, D.W.1
-
17
-
-
0036916491
-
On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: Critical importance of the position of the oxygen function
-
DOI 10.1194/jlr.M200293-JLR200
-
Meaney S, Bodin K, Diczfalusy U, Bjorkhem I. On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function. J Lipid Res 2002;43:2130-5. (Pubitemid 35471081)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.12
, pp. 2130-2135
-
-
Meaney, S.1
Bodin, K.2
Diczfalusy, U.3
Bjorkhem, I.4
-
19
-
-
0023221061
-
Accumulation of 7-hydroxy-4-cholesten-3-one and cholesta-4,6-dien-3-one in patients with cerebrotendinous xanthomatosis: Effect of treatment with chenodeoxycholic acid
-
DOI 10.1002/hep.1840070210
-
Björkhem I, Skrede S, Buchmann MS, East C, Grundy S. Accumulation of 7 alpha-hydroxy-4-cholesten-3-one and cholesta-4,6-dien-3-one in patients with cerebrotendinous xanthomatosis: effect of treatment with chenodeoxycholic acid. Hepatology 1987;7:266-71. (Pubitemid 17062715)
-
(1987)
Hepatology
, vol.7
, Issue.2
, pp. 266-271
-
-
Bjorkheim, I.1
Skrede, S.2
Buchmann, M.S.3
-
20
-
-
0032918516
-
Increased plasma 7-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease
-
Zieden B, Kaminskas A, Kristenson M, Kucinskiene Z, Vesseby B, Olsson AG, et al. Increased plasma 7b-hydroxycholesterol concentrations in a population with high risk for cardiovascular disease. Arterioscler Thromb Vasc Biol 1999;19:967-71. (Pubitemid 29177344)
-
(1999)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.19
, Issue.4
, pp. 967-971
-
-
Zieden, B.1
Kaminskas, A.2
Kristenson, M.3
Kucinskiene, Z.4
Vessby, B.5
Olsson, A.G.6
Diczfalusy, U.7
-
21
-
-
63249096864
-
Oxysterols and mechanisms of apoptotic signaling: Implications in the pathology of degenerative diseases
-
Lordan S, Mackrill JJ, O'Brien NM. Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases. J Nutr Biochem 2009;20:321-36.
-
(2009)
J Nutr Biochem
, vol.20
, pp. 321-336
-
-
Lordan, S.1
Mackrill, J.J.2
O'brien, N.M.3
-
22
-
-
67349159434
-
Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis
-
Vejux A, Lizard G. Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis. Mol Aspects Med 2009;30:153-70.
-
(2009)
Mol Aspects Med
, vol.30
, pp. 153-170
-
-
Vejux, A.1
Lizard, G.2
-
23
-
-
77954217091
-
Interaction of two oxysterols, 7-ketocholesterol and 25- hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes
-
Mintzer E, Charles G, Gordon S. Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes. Chem Phys Lipids 2010;163:586-93.
-
(2010)
Chem Phys Lipids
, vol.163
, pp. 586-593
-
-
Mintzer, E.1
Charles, G.2
Gordon, S.3
-
24
-
-
67650179212
-
7-ketocholesterol incorporation into sphingolipid/cholesterolenriched (lipid raft) domains is impaired by vitamin E: A specific role for alpha-tocopherol with consequences on cell death
-
Royer MC, Lemaire-Ewing S, Desrumaux C, Monier S, Pais de Barros JP, Athias A, et al. 7-ketocholesterol incorporation into sphingolipid/ cholesterolenriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death. J Biol Chem 2009;284:15826-34.
-
(2009)
J Biol Chem
, vol.284
, pp. 15826-15834
-
-
Royer, M.C.1
Lemaire-Ewing, S.2
Desrumaux, C.3
Monier, S.4
Pais De Barros, J.P.5
Athias, A.6
-
25
-
-
79953016042
-
Impact of 7- ketocholesterol and very long chain fatty acids on oligodendrocyte lipid membrane organization: Evaluation via LAURDAN and FAMIS spectral image analysis
-
Kahn E, Baarine M, Dauphin A, Ragot K, Tissot N, Seguin A, et al. Impact of 7- ketocholesterol and very long chain fatty acids on oligodendrocyte lipid membrane organization: evaluation via LAURDAN and FAMIS spectral image analysis. Cytometry A 2011;79:293-305.
-
(2011)
Cytometry A
, vol.79
, pp. 293-305
-
-
Kahn, E.1
Baarine, M.2
Dauphin, A.3
Ragot, K.4
Tissot, N.5
Seguin, A.6
-
26
-
-
80051472674
-
A-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158 N murine oligodendrocytes
-
Ragot K, Delmas D, Athias A, Nury T, Baarine M, Lizard G. a-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158 N murine oligodendrocytes. Chem Phys Lipids 2011;164:469-78.
-
(2011)
Chem Phys Lipids
, vol.164
, pp. 469-478
-
-
Ragot, K.1
Delmas, D.2
Athias, A.3
Nury, T.4
Baarine, M.5
Lizard, G.6
-
27
-
-
1642281535
-
Relapsing and Remitting Multiple Sclerosis: Pathology of the Newly Forming Lesion
-
DOI 10.1002/ana.20016
-
Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 2004;55:458-68. (Pubitemid 38391962)
-
(2004)
Annals of Neurology
, vol.55
, Issue.4
, pp. 458-468
-
-
Barnett, M.H.1
Prineas, J.W.2
-
28
-
-
85030491303
-
Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: A link between demyelination and neuronal damage
-
Diestel A, Aktas O, Hackel D, Hake I, Meier S, Raine CS, et al. Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage. J Exp Med 1981;2003:729-40.
-
(1981)
J Exp Med
, vol.2003
, pp. 729-740
-
-
Diestel, A.1
Aktas, O.2
Hackel, D.3
Hake, I.4
Meier, S.5
Raine, C.S.6
-
29
-
-
13944273308
-
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis
-
DOI 10.1194/jlr.C400005-JLR200
-
Leoni V, Lutjohann D, Mastermann T. Levels of 7-oxocholesterol in cerebrospinal fluid in patients with multiple sclerosis are more than a thousand times lower than reported. J Lipid Res 2005;46:191-5. (Pubitemid 40271081)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.2
, pp. 191-195
-
-
Leoni, V.1
Lutjohann, D.2
Masterman, T.3
-
30
-
-
0029835410
-
Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
-
DOI 10.1073/pnas.93.18.9799
-
Lütjohann D, Breuer O, Ahlborg G, Nennesmo I, Siden A, Diczfalusy U, et al. Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proc Natl Acad Sci USA 1996;93:9799-804. (Pubitemid 26296689)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.18
, pp. 9799-9804
-
-
Lutjohann, D.1
Breuer, O.2
Ahlborg, G.3
Nennesmo, I.4
Siden, A.5
Diczfalusy, U.6
Bjorkhem, I.7
-
31
-
-
0141459395
-
Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration
-
DOI 10.1194/jlr.M300164-JLR200
-
Xie C, Lund EG, Turley SD, Russell DW, Dietschy JM. Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration. J Lipid Res 2003;44:1780-9. (Pubitemid 37185890)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.9
, pp. 1780-1789
-
-
Xie, C.1
Lund, E.G.2
Turley, S.D.3
Russell, D.W.4
Dietschy, J.M.5
-
32
-
-
0030062778
-
Importance of a novel oxidative mechanism for elimination of intracellular cholesterol in humans
-
Lund EO, Andersson O, Zheng J, Babiker A, Ahlborg G, Diczfalusy U, et al. Importance of a novel oxidative mechanism for elimination of intracellular cholesterol in humans. Artherioscler Thromb Vasc Biol 1996;16:208-12. (Pubitemid 26056238)
-
(1996)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.16
, Issue.2
, pp. 208-212
-
-
Lund, E.1
Andersson, O.2
Zhang, J.3
Babiker, A.4
Ahlborg, G.5
Diczfalusy, U.6
Einarsson, K.7
Sjovall, J.8
Bjorkhem, I.9
-
33
-
-
33744948883
-
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux
-
DOI 10.1074/jbc.M601019200
-
Abildayeva K, Jansen PJ, Hirsch-Reinshagen V, Bloks VW, Bakker AH, Ramaekers FC, et al. 24(S)-hydroxycholesterol participates in a liver X receptorcontrolled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. J Biol Chem 2006;281:12799-808. (Pubitemid 43855372)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.18
, pp. 12799-12808
-
-
Abildayeva, K.1
Jansen, P.J.2
Hirsch-Reinshagen, V.3
Bloks, V.W.4
Bakker, A.H.F.5
Ramaekers, F.C.S.6
De Vente, J.7
Groen, A.K.8
Wellington, C.L.9
Kuipers, F.10
Mulder, M.11
-
34
-
-
42049122331
-
ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain
-
DOI 10.1096/fj.07-9944com
-
Wang N, Yvan-Charvet L, Lü tjohann D, Mulder M, Vanmierlo T, Kim TW, et al. ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain. FASEB J 2008;22:1073-82. (Pubitemid 351519962)
-
(2008)
FASEB Journal
, vol.22
, Issue.4
, pp. 1073-1082
-
-
Wang, N.1
Yvan-Charvet, L.2
Lutjohann, D.3
Mulder, M.4
Vanmierlo, T.5
Kim, T.-W.6
Tall, A.R.7
-
35
-
-
33644868456
-
Brain cholesterol turnover required for geranylgeraniol production and learning in mice
-
DOI 10.1073/pnas.0600316103
-
Kotti TJ, Ramirez DM, Pfeiffer BE, Huber KM, Russell DW. Brain cholesterol turnover required for geranylgeraniol production and learning in mice. Proc Natl Acad Sci USA 2006;103:3869-74. (Pubitemid 43376647)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.10
, pp. 3869-3874
-
-
Kotti, T.J.1
Ramirez, D.M.O.2
Pfeiffer, B.E.3
Huber, K.M.4
Russell, D.W.5
-
36
-
-
67349268463
-
Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis
-
Brown AJ, Oxysterols Jessup W. Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. Mol Aspects Med 2009;30:111-22.
-
(2009)
Mol Aspects Med
, vol.30
, pp. 111-122
-
-
Brown, A.J.1
Oxysterols Jessup, W.2
-
37
-
-
0036172426
-
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis
-
Upston JM, Niu X, Brown AJ, Mashima R, Wang H, Senthilmohan R, et al. Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis. Am J Pathol 2002;160:701-10. (Pubitemid 34160348)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.2
, pp. 701-710
-
-
Upston, J.M.1
Niu, X.2
Brown, A.J.3
Mashima, R.4
Wang, H.5
Senthilmohan, R.6
Kettle, A.J.7
Dean, R.T.8
Stocker, R.9
-
38
-
-
79151470239
-
Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism
-
Karuna R, Holleboom AG, Motazacker MM, Kuivenhoven JA, Frikke-Schmidt R, Tybjaerg-Hansen A, et al. Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism. Atherosclerosis 2011;214:448-55.
-
(2011)
Atherosclerosis
, vol.214
, pp. 448-455
-
-
Karuna, R.1
Holleboom, A.G.2
Motazacker, M.M.3
Kuivenhoven, J.A.4
Frikke-Schmidt, R.5
Tybjaerg-Hansen, A.6
-
39
-
-
23644442259
-
Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid
-
Babiker A, Dzeletovic S, Wiklund B, Pettersson N, Salonen J, Nyyssönen K, et al. Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid. Scand J Clin Lab Invest 2005;65:365-75.
-
(2005)
Scand J Clin Lab Invest
, vol.65
, pp. 365-375
-
-
Babiker, A.1
Dzeletovic, S.2
Wiklund, B.3
Pettersson, N.4
Salonen, J.5
Nyyssönen, K.6
-
40
-
-
0031045545
-
Metabolism of 27-, 25- and 24-hydroxycholesterol in rat glial cells and neurons
-
Zhang J, Akwa Y, el-Etr M, Baulieu EE, Sjö vall J. Metabolism of 27-, 25- and 24- hydroxycholesterol in rat glial cells and neurons. Biochem J 1997;322:175- 84. (Pubitemid 27095538)
-
(1997)
Biochemical Journal
, vol.322
, Issue.1
, pp. 175-184
-
-
Zhang, J.1
Akwa, Y.2
El-Etr, M.3
Baulieu, E.-E.4
Sjovall, J.5
-
41
-
-
0842303768
-
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
-
DOI 10.1194/jlr.M300320-JLR200
-
Heverin M, Bogdanovic N, Lutjohann D, Bayer T, Pikuleva I, Bretillon L, et al. Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease. J Lipid Res 2004;45:186-93. (Pubitemid 38180529)
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.1
, pp. 186-193
-
-
Heverin, M.1
Bogdanovic, N.2
Lutjohann, D.3
Bayer, T.4
Pikuleva, I.5
Bretillon, L.6
Diczfalusy, U.7
Winblad, B.8
Bjorkhem, I.9
-
42
-
-
79955038570
-
Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation
-
Shafaati M, Marutle A, Pettersson H, Lövgren-Sandblom A, Olin M, Pikuleva I, et al. Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation. J Lipid Res 2011;52:1004-10.
-
(2011)
J Lipid Res
, vol.52
, pp. 1004-1010
-
-
Shafaati, M.1
Marutle, A.2
Pettersson, H.3
Lövgren-Sandblom, A.4
Olin, M.5
Pikuleva, I.6
-
43
-
-
4544255297
-
Differential expression of cholesterol hydroxylases in Alzheimer's disease
-
DOI 10.1074/jbc.M402324200
-
Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, et al. Differential expression of cholesterol hydroxylases in alzheimer's disease. J Biol Chem 2004;279:34674-81. (Pubitemid 39318097)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34674-34681
-
-
Brown III, J.1
Theisler, C.2
Silberman, S.3
Magnuson, D.4
Gottardi-Littell, N.5
Lee, J.M.6
Yager, D.7
Crowley, J.8
Sambamurti, K.9
Rahman, M.M.10
Reiss, A.B.11
Eckman, C.B.12
Wolozin, B.13
-
44
-
-
0141700567
-
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers
-
DOI 10.1194/jlr.M200434-JLR200
-
Leoni V, Masterman T, Patel P, Meaney S, Diczfalusy U, Björkhem I. Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers. J Lipid Res 2003;44:793-9. (Pubitemid 37279681)
-
(2003)
Journal of Lipid Research
, vol.44
, Issue.4
, pp. 793-799
-
-
Leoni, V.1
Masterman, T.2
Patel, P.3
Meaney, S.4
Diczfalusy, U.5
Bjorkhem, I.6
-
45
-
-
23744498856
-
Crossing the barrier: Net flux of 27-hydroxycholesterol into the human brain
-
Heverin M, Meaney S, Lü tjohann D, Diczfalusy U, Wahren J, Björkhem I. Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain. J Lipid Res 2005;46:1047-52.
-
(2005)
J Lipid Res
, vol.46
, pp. 1047-1052
-
-
Heverin, M.1
Meaney, S.2
Lü Tjohann, D.3
Diczfalusy, U.4
Wahren, J.5
Björkhem, I.6
-
46
-
-
34147141285
-
Novel route for elimination of brain oxysterols across the blood-brain barrier: Conversion into 7-hydroxy-3-oxo-4-cholestenoic acid
-
DOI 10.1194/jlr.M600529-JLR200
-
Meaney S, Heverin M, Panzenboeck U, Ekström L, Axelsson M, Andersson U, et al. Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into7alpha-hydroxy-3-oxo-4-cholestenoic acid. J Lipid Res 2007;48:944-51. (Pubitemid 46557899)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.4
, pp. 944-951
-
-
Meaney, S.1
Heverin, M.2
Panzenboeck, U.3
Ekstrom, L.4
Axelsson, M.5
Andersson, U.6
Diczfalusy, U.7
Pikuleva, I.8
Wahren, J.9
Sattler, W.10
Bjorkhem, I.11
-
47
-
-
79953731158
-
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease
-
Mateos L, Ismail MA, Gil-Bea FJ, Leoni V, Winblad B, Björkhem I, et al. Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease. J Alzheimers Dis 2011;24:669-79.
-
(2011)
J Alzheimers Dis
, vol.24
, pp. 669-679
-
-
Mateos, L.1
Ismail, M.A.2
Gil-Bea, F.J.3
Leoni, V.4
Winblad, B.5
Björkhem, I.6
-
48
-
-
33746310315
-
Alzheimer's disease
-
DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
-
Blennow K, De Leon MJ, Zetterberg H. Alzheimer's disease. Lancet 2006;368:387-403. (Pubitemid 44108123)
-
(2006)
Lancet
, vol.368
, Issue.9533
, pp. 387-403
-
-
Blennow, K.1
De Leon, M.J.2
Zetterberg, H.3
-
49
-
-
79955051063
-
Linking lipids to Alzheimer's disease: Cholesterol and beyond
-
Di Paolo G, Kim TW. Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat Rev Neurosci 2011;12:284-96.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 284-296
-
-
Di Paolo, G.1
Kim, T.W.2
-
50
-
-
0032568843
-
Modulation of secreted amyloid peptide in brain by cholesterol
-
DOI 10.1074/jbc.273.26.16576
-
Howland DS, Trusko SP, Savage MJ, Reaume AG, Lang DM, Hirsch JD, et al. Modulation of secreted beta-amyloid precursor protein and amyloid betapeptide in brain by cholesterol. J Biol Chem 1998;273:16576-82. (Pubitemid 28311445)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.26
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maedas, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
51
-
-
0033519601
-
The role of cholesterol in the biosynthesis of beta-amyloid
-
Frears ER, Stephens DJ, Walters CE, Davies H, Austen BM. The role of cholesterol in the biosynthesis of beta-amyloid. Neuroreport 1999;10:1699-705.
-
(1999)
Neuroreport
, vol.10
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
52
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz S, Klein WL. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 1996;271:4436-40.
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
53
-
-
0027327267
-
Association of apolipoprotein E allele 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak- Vance MA, Joo SH, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-72. (Pubitemid 23230526)
-
(1993)
Neurology
, vol.43
, Issue.8
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop St., P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-MacLachlan, D.R.9
Alberts, M.J.10
Hulette, C.11
Crain, B.12
Goldgaber, D.13
Roses, A.D.14
-
54
-
-
66549106850
-
Alzheimer's Disease Neuroimaging Initiative. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease
-
Jack Jr CR, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, et al. Alzheimer's Disease Neuroimaging Initiative. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain 2009;132:1355-65.
-
(2009)
Brain
, vol.132
, pp. 1355-1365
-
-
Jack Jr., C.R.1
Lowe, V.J.2
Weigand, S.D.3
Wiste, H.J.4
Senjem, M.L.5
Knopman, D.S.6
-
55
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack Jr CR, Knopman DS, Jagust WJ, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 2010;9:119-28.
-
(2010)
Lancet Neurol
, vol.9
, pp. 119-128
-
-
Jack Jr., C.R.1
Knopman, D.S.2
Jagust, W.J.3
-
56
-
-
65549150954
-
Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity
-
Nicholson AM, Ferreira A. Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity. J Neurosci 2009;29: 4640-51.
-
(2009)
J Neurosci
, vol.29
, pp. 4640-4651
-
-
Nicholson, A.M.1
Ferreira, A.2
-
57
-
-
0028035306
-
Isoform-specific interactionsof apolipoprotein e with microtubuleassociated protein tau: Implications for Alzheimer disease
-
Strittmatter WJ, Saunders AM, Goedert M, Weisgraber KH, Dong LM, Jakes R, et al. Isoform-specific interactionsof apolipoprotein E with microtubuleassociated protein tau: implications for Alzheimer disease. Proc Natl Acad Sci USA 1994;91:11183-86.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11183-11186
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Goedert, M.3
Weisgraber, K.H.4
Dong, L.M.5
Jakes, R.6
-
58
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, et al. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 2000;7:321-31.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
Lafrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
-
59
-
-
0037171095
-
Diet-induced hypercholesterolemia enhances brain Aaccumulation in transgenic mice
-
Shie FS, Jin LW, Cook DG, Leverenz JB, LeBoeuf RC. Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice. Neuroreport 2002;13:455-9. (Pubitemid 34293189)
-
(2002)
NeuroReport
, vol.13
, Issue.4
, pp. 455-459
-
-
Shie, F.-S.1
Jin, L.-W.2
Cook, D.G.3
Leverenz, J.B.4
LeBoeuf, R.C.5
-
60
-
-
80052864023
-
Cholesterol and amyloid-b: Evidence for a cross-talk between astrocytes and neuronal cells
-
Canepa E, Borghi R, Vina J, Traverso N, Gambini J, Domenicotti C, et al. Cholesterol and amyloid-b: evidence for a cross-talk between astrocytes and neuronal cells. J Alzheimers Dis 2011;25(4):645-53.
-
(2011)
J Alzheimers Dis
, vol.25
, Issue.4
, pp. 645-653
-
-
Canepa, E.1
Borghi, R.2
Vina, J.3
Traverso, N.4
Gambini, J.5
Domenicotti, C.6
-
61
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the secretase ADAM 10
-
DOI 10.1073/pnas.081612998
-
Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. Proc Natl Acad Sci USA 2001;98:5815-20. (Pubitemid 32435725)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.10
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
62
-
-
0032568552
-
Cholesterol depletion inhibits the generation of amyloid in hippocampal neurons
-
DOI 10.1073/pnas.95.11.6460
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc Natl Acad Sci USA 1998;95:6460-4. (Pubitemid 28249035)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
63
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease amyloid peptides A42 and A40 in vitro and in vivo
-
DOI 10.1073/pnas.081620098
-
Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P, et al. Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc Natl Acad Sci USA 2001;98:5856-61. (Pubitemid 32435732)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.10
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
Runz, H.7
Kuhl, S.8
Bertsch, T.9
Von Bergmann, K.10
Hennerici, M.11
Beyreuther, K.12
Hartmann, T.13
-
64
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer amyloid precursor protein depends on lipid rafts
-
DOI 10.1083/jcb.200207113
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K. Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol 2003;160:113-23. (Pubitemid 36091721)
-
(2003)
Journal of Cell Biology
, vol.160
, Issue.1
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
65
-
-
39249084075
-
Cholesterol retention in Alzheimer's brain is responsible for high beta- and gammasecretase activities and Abeta production
-
Xiong H, Callaghan D, Jones A, Walker DG, Lue LF, Beach TG, et al. Cholesterol retention in Alzheimer's brain is responsible for high beta- and gammasecretase activities and Abeta production. Neurobiol Dis 2008;29:422-37.
-
(2008)
Neurobiol Dis
, vol.29
, pp. 422-437
-
-
Xiong, H.1
Callaghan, D.2
Jones, A.3
Walker, D.G.4
Lue, L.F.5
Beach, T.G.6
-
66
-
-
77957959900
-
Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits
-
Ullrich C, Pirchl M, Humpel C. Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits. Mol Cell Neurosci 2010;45:408-17.
-
(2010)
Mol Cell Neurosci
, vol.45
, pp. 408-417
-
-
Ullrich, C.1
Pirchl, M.2
Humpel, C.3
-
67
-
-
79953229512
-
Dietary cholesterol and its effect on tau protein: A study in apolipoprotein E-deficient and P301L human tau mice
-
Glockner F, Meske V, Lutjohann D, Ohm TG. Dietary cholesterol and its effect on tau protein: a study in apolipoprotein E-deficient and P301L human tau mice. J Neuropathol Exp Neurol 2011;70:292-301.
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, pp. 292-301
-
-
Glockner, F.1
Meske, V.2
Lutjohann, D.3
Ohm, T.G.4
-
68
-
-
27744511921
-
High cholesterol diet induces tau hyperphosphorylation in apolipoprotein e deficient mice
-
DOI 10.1016/j.febslet.2005.10.024, PII S0014579305012846
-
Rahman A, Akterin S, Flores-Morales A, Crisby M, Kivipelto M, Schultzberg M, et al. High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice. FEBS Lett 2005;579:6411-6. (Pubitemid 41612160)
-
(2005)
FEBS Letters
, vol.579
, Issue.28
, pp. 6411-6416
-
-
Rahman, A.1
Akterin, S.2
Flores-Morales, A.3
Crisby, M.4
Kivipelto, M.5
Schultzberg, M.6
Cedazo-Minguez, A.7
-
69
-
-
33745757155
-
Cholesterol as a risk factor for Alzheimer's disease - Epidemiological evidence
-
DOI 10.1111/j.1600-0404.2006.00685.x
-
Kivipelto M, Solomon A. Cholesterol as a risk factor for Alzheimer's disease - epidemiological evidence. Acta Neurol Scand Suppl 2006;185:50-7. (Pubitemid 44015225)
-
(2006)
Acta Neurologica Scandinavica
, vol.114
, Issue.SUPPL. 185
, pp. 50-57
-
-
Kivipelto, M.1
Solomon, A.2
-
70
-
-
67749114631
-
Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
-
Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA. Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later. Dement Geriatr Cogn Disord 2009;28:75-80.
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, pp. 75-80
-
-
Solomon, A.1
Kivipelto, M.2
Wolozin, B.3
Zhou, J.4
Whitmer, R.A.5
-
71
-
-
67650432608
-
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease
-
Solomon A, Leoni V, Kivipelto M, Besga A, Oksengard AR, Julin P, et al. Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. Neurosci Lett 2009;462:89-93.
-
(2009)
Neurosci Lett
, vol.462
, pp. 89-93
-
-
Solomon, A.1
Leoni, V.2
Kivipelto, M.3
Besga, A.4
Oksengard, A.R.5
Julin, P.6
-
72
-
-
33846061128
-
Twenty-six-year change in total cholesterol levels and incident dementia: The Honolulu-Asia aging study
-
DOI 10.1001/archneur.64.1.103
-
Stewart R, White LR, Xue QL, Launer LJ. Twenty-six-year change in total cholesterol levels and incident dementia: the Honolulu-Asia Aging Study. Arch Neurol 2007;64:103-7. (Pubitemid 46072431)
-
(2007)
Archives of Neurology
, vol.64
, Issue.1
, pp. 103-107
-
-
Stewart, R.1
White, L.R.2
Xue, Q.-L.3
Launer, L.J.4
-
73
-
-
62149140601
-
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol onbeta-amyloid precursor protein levels and processing in human neuroblastomaSH- SY5Y cells
-
Prasanthi JR, Huls A, Thomasson S, Thompson A, Schommer E, Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol onbeta-amyloid precursor protein levels and processing in human neuroblastomaSH- SY5Y cells. Mol Neurodegener 2009;4:1.
-
(2009)
Mol Neurodegener
, vol.4
, pp. 1
-
-
Prasanthi, J.R.1
Huls, A.2
Thomasson, S.3
Thompson, A.4
Schommer, E.5
Ghribi, O.6
-
74
-
-
34249828178
-
Regulation of and secretase activity by oxysterols: Cerebrosterol stimulates processing of APP via the secretase pathway
-
DOI 10.1016/j.bbrc.2007.05.033, PII S0006291X07009953
-
Famer D, Meaney S, Mousavi M, Nordberg A, Bjorkhem I, Crisby M. Regulation of alpha- and betasecretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway. Biochem Biophys Res Commun 2007;359:46-50. (Pubitemid 46844819)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.359
, Issue.1
, pp. 46-50
-
-
Famer, D.1
Meaney, S.2
Mousavi, M.3
Nordberg, A.4
Bjorkhem, I.5
Crisby, M.6
-
75
-
-
77956494238
-
The oxysterol 27- hydroxycholesterol increases b-amyloid and oxidative stress in retinal pigment epithelial cells
-
http://www.biomedcentral.com/1471-2415/10/22
-
Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O. The oxysterol 27- hydroxycholesterol increases b-amyloid and oxidative stress in retinal pigment epithelial cells. BMC Ophthalmol 2010; http://dx.doi.org/10.1186/ 1471-2415-10-22, http://www.biomedcentral.com/1471-2415/10/22.
-
(2010)
BMC Ophthalmol
-
-
Dasari, B.1
Prasanthi, J.R.2
Marwarha, G.3
Singh, B.B.4
Ghribi, O.5
-
76
-
-
80054680024
-
Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus
-
Prasanthi JR, Larson T, Schommer J, Ghribi O. Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. PLoS ONE 2011;6:e26420. http://dx.doi.org/10.1371/journal.pone.0026420.
-
(2011)
PLoS ONE
, vol.6
-
-
Prasanthi, J.R.1
Larson, T.2
Schommer, J.3
Ghribi, O.4
-
78
-
-
80051472136
-
Oxysterols as biomarkers in neurodegenerative diseases
-
Leoni V, Caccia C. Oxysterols as biomarkers in neurodegenerative diseases. Chem Phys Lipids 2011;164:515-24.
-
(2011)
Chem Phys Lipids
, vol.164
, pp. 515-524
-
-
Leoni, V.1
Caccia, C.2
-
79
-
-
84874107996
-
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases
-
pii:S0300- 9084(12)00385-9 [epub ahead of print].
-
Leoni V, Caccia C. 24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases. Biochimie 2012; pii:S0300- 9084(12)00385-9, http://dx.doi.org/10.1016/j.biochi.2012.09.025 [epub ahead of print].
-
(2012)
Biochimie
-
-
Leoni, V.1
Caccia, C.2
-
80
-
-
33751096969
-
Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain
-
DOI 10.1111/j.1365-2796.2006.01725.x
-
Björkhem I. Crossing the barrier, oxysterols as cholesterol transporters and metabolic modulators in the brain. J Intern Med 2006;260:493-508. (Pubitemid 44772369)
-
(2006)
Journal of Internal Medicine
, vol.260
, Issue.6
, pp. 493-508
-
-
Bjorkhem, I.1
-
81
-
-
0343729334
-
Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface
-
Bretillon L, Lutjohann D, Stahle L, Widhe T, Bindl L, Eggersten G, et al. Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface. J Lipid Res 2000;41:840-5. (Pubitemid 30314140)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.5
, pp. 840-845
-
-
Bretillon, L.1
Lutjohann, D.2
Stahle, L.3
Widhe, T.4
Bindl, L.5
Eggertsen, G.6
Diczfalusy, U.7
Bjorkhem, I.8
-
82
-
-
0034722108
-
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases
-
Bretillon L, Siden A, Wahlund LO, Lü tjohann D, Minthon L, Crisby M, et al. Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases. Neurosci Lett 2000;293:87-90.
-
(2000)
Neurosci Lett
, vol.293
, pp. 87-90
-
-
Bretillon, L.1
Siden, A.2
Wahlund, L.O.3
Lü Tjohann, D.4
Minthon, L.5
Crisby, M.6
-
83
-
-
4544282709
-
Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients
-
DOI 10.1016/j.neulet.2004.07.031, PII S0304394004008961
-
Kolsch H, Heun R, Kerksiek A, Bergmann KV, Maier W, Lutjohann D. Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients. Neurosci Lett 2004;368:303-8. (Pubitemid 39214973)
-
(2004)
Neuroscience Letters
, vol.368
, Issue.3
, pp. 303-308
-
-
Kolsch, H.1
Heun, R.2
Kerksiek, A.3
Bergmann, K.V.4
Maier, W.5
Lutjohann, D.6
-
84
-
-
0041589132
-
Decreased levels of the brain specific 24S-hydroxycholesterol and cholesterol precursors in serum of multiple sclerosis patients
-
DOI 10.1016/S0304-3940(03)00667-0
-
Teunissen CE, Dijkstra CD, Polman CH, Hoogervorst EL, von Bergmann K, Lü tjohann D. Decreased levels of the brain specific 24S-hydroxycholesterol and cholesterol precursors in serum of multiple sclerosis patients. Neurosci Lett 2003;347:159-62. (Pubitemid 37271941)
-
(2003)
Neuroscience Letters
, vol.347
, Issue.3
, pp. 159-162
-
-
Teunissen, C.E.1
Dijkstra, C.D.2
Polman, C.H.3
Hoogervorst, E.L.J.4
Von Bergmann, K.5
Lutjohann, D.6
-
85
-
-
0043092171
-
Combination of serum markers related to several mechanisms in Alzheimer's disease
-
DOI 10.1016/S0197-4580(03)00005-8
-
Teunissen CE, Lü tjohann D, von Bergmann K, Verhey F, Vreeling F, Wauters A, et al. Combination of serum markers related to several mechanisms in Alzheimer's disease. Neurobiol Aging 2003;24:893-902. (Pubitemid 36962973)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.7
, pp. 893-902
-
-
Teunissen, C.E.1
Lutjohann, D.2
Von Bergmann, K.3
Verhey, F.4
Vreeling, F.5
Wauters, A.6
Bosmans, E.7
Bosma, H.8
Van Boxtel, M.P.J.9
Maes, M.10
Delanghe, J.11
Blom, H.J.12
Verbeek, M.M.13
Rieckmann, P.14
De Bruijn, C.15
Steinbusch, H.W.M.16
De Vente, J.17
-
86
-
-
0037131563
-
Changes in human plasma levels of 24S-hydroxycholesterol during progression of multiple sclerosis
-
Leoni V, Masterman T, Diczfalusy U, De Luca G, Hillert J, Björkhem I. Changes in human plasma levels of 24S-hydroxycholesterol during progression of multiple sclerosis. Neurosci Lett 2002;331:163-6.
-
(2002)
Neurosci Lett
, vol.331
, pp. 163-166
-
-
Leoni, V.1
Masterman, T.2
Diczfalusy, U.3
De Luca, G.4
Hillert, J.5
Björkhem, I.6
-
87
-
-
55749085638
-
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease
-
Leoni V, Mariotti C, Tabrizi SJ, Valenza M, Wild EJ, Henley SM, et al. Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease. Brain 2008;131:2851-9.
-
(2008)
Brain
, vol.131
, pp. 2851-2859
-
-
Leoni, V.1
Mariotti, C.2
Tabrizi, S.J.3
Valenza, M.4
Wild, E.J.5
Henley, S.M.6
-
88
-
-
79954420690
-
Whole body cholesterol metabolism is impaired in Huntington's disease
-
Leoni V, Mariotti C, Nanetti L, Salvatore E, Squitieri F, Bentivoglio AR, et al. Whole body cholesterol metabolism is impaired in Huntington's disease. Neurosci Lett 2011;494:245-9.
-
(2011)
Neurosci Lett
, vol.494
, pp. 245-249
-
-
Leoni, V.1
Mariotti, C.2
Nanetti, L.3
Salvatore, E.4
Squitieri, F.5
Bentivoglio, A.R.6
-
89
-
-
33646752106
-
Plasma cerebrosterol and magnetic resonance imaging measures in multiple sclerosis
-
DOI 10.1016/j.clineuro.2005.07.010, PII S0303846705001423
-
Danylaite Karrenbauer V, Leoni V, Lim ET, Giovannoni G, Ingle GT, Sastre- Garriga J, et al. Plasma cerebrosterol and magnetic resonance imaging measures in multiple sclerosis. Clin Neurol Neurosurg 2006;108: 456-60. (Pubitemid 43744509)
-
(2006)
Clinical Neurology and Neurosurgery
, vol.108
, Issue.5
, pp. 456-460
-
-
Karrenbauer, V.D.1
Leoni, V.2
Lim, E.T.3
Giovannoni, G.4
Ingle, G.T.5
Sastre-Garriga, J.6
Thompson, A.J.7
Rashid, W.8
Davies, G.9
Miller, D.H.10
Bjorkhem, I.11
Masterman, T.12
-
90
-
-
50849131196
-
CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk
-
Qureischie H, Heun R, Lü tjohann D, Popp J, Jessen F, Ledschbor-Frahnert C, et al. CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk. Brain Res 2008;1232:1-6.
-
(2008)
Brain Res
, vol.1232
, pp. 1-6
-
-
Qureischie, H.1
Heun, R.2
Lü Tjohann, D.3
Popp, J.4
Jessen, F.5
Ledschbor-Frahnert, C.6
-
91
-
-
84856767053
-
Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms
-
Besga A, Cedazo-Minguez A, Kareholt I, Solomon A, Björkhem I, Winblad B, et al. Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms. Neurosci Lett 2012;510:121-6.
-
(2012)
Neurosci Lett
, vol.510
, pp. 121-126
-
-
Besga, A.1
Cedazo-Minguez, A.2
Kareholt, I.3
Solomon, A.4
Björkhem, I.5
Winblad, B.6
-
92
-
-
80053557887
-
Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: A case-control study
-
Zuliani G, Donnorso MP, Bosi C, Passaro A, Dalla Nora E, Zurlo A, et al. Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study. BMC Neurol 2011;11:121.
-
(2011)
BMC Neurol
, vol.11
, pp. 121
-
-
Zuliani, G.1
Donnorso, M.P.2
Bosi, C.3
Passaro, A.4
Dalla Nora, E.5
Zurlo, A.6
-
93
-
-
0035985702
-
Oxysterols in human circulation: Which role do they have?
-
DOI 10.1097/00041433-200206000-00003
-
Bjorkhem I, Meaney S, Diczfalusy U. Oxysterols in human circulation: which role do they have. Curr Opin Lipidol 2002;13:247-53. (Pubitemid 34592280)
-
(2002)
Current Opinion in Lipidology
, vol.13
, Issue.3
, pp. 247-253
-
-
Bjorkhem, I.1
Meaney, S.2
Diczfalusy, U.3
-
94
-
-
84873661818
-
Brain cholesterol metabolism, oxysterols, and dementia
-
[epub ahead of print]
-
Hughes TM, Rosano C, Evans RW, Kuller LH. Brain cholesterol metabolism, oxysterols, and dementia. J Alzheimers Dis 2012; http://dx.doi.org/10.3233/ JAD-2012-121585 [epub ahead of print].
-
(2012)
J Alzheimers Dis
-
-
Hughes, T.M.1
Rosano, C.2
Evans, R.W.3
Kuller, L.H.4
-
95
-
-
0343775806
-
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients
-
Lü tjohann D, Papassotiropoulos A, Björkhem I, Locatelli S, Bagli M, Oehring RD, et al. Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res 2000;41:195-8. (Pubitemid 30117859)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.2
, pp. 195-198
-
-
Lutjohann, D.1
Papassotiropoulos, A.2
Bjorkhem, I.3
Locatelli, S.4
Bagli, M.5
Oehring, R.D.6
Schlegel, U.7
Jessen, F.8
Rao, M.L.9
Von Bergmann, K.10
Heun, R.11
-
96
-
-
84867091169
-
Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease
-
Popp J, Lewczuk P, Kö lsch H, Meichsner S, Maier W, Kornhuber J, et al. Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease. J Neurochem 2012;123:310-6.
-
(2012)
J Neurochem
, vol.123
, pp. 310-316
-
-
Popp, J.1
Lewczuk, P.2
Kö Lsch, H.3
Meichsner, S.4
Maier, W.5
Kornhuber, J.6
-
97
-
-
84884339335
-
Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's Disease
-
[epub ahead of print]
-
Popp J, Meichsner S, Kö lsch H, Lewczuk P, Maier W, Kornhuber J, et al. Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's Disease. Biochem Pharmacol 2013; [epub ahead of print]: http://www.sciencedirect.com/science/article/pii/S0006295212007939.
-
(2013)
Biochem Pharmacol
-
-
Popp, J.1
Meichsner, S.2
Kö Lsch, H.3
Lewczuk, P.4
Maier, W.5
Kornhuber, J.6
-
98
-
-
84861501372
-
Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease
-
Hughes TM, Kuller LH, Lopez OL, Becker JT, Evans RW, Sutton-Tyrrell K, et al. Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease. J Alzheimers Dis 2012;30:53-61.
-
(2012)
J Alzheimers Dis
, vol.30
, pp. 53-61
-
-
Hughes, T.M.1
Kuller, L.H.2
Lopez, O.L.3
Becker, J.T.4
Evans, R.W.5
Sutton-Tyrrell, K.6
-
99
-
-
78149342830
-
Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease
-
Porter FD, Scherrer DE, Lanier MH, Langmade SJ, Molugu V, Gale SE, et al. Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease. Sci Transl Med 2010;2:56ra81.
-
(2010)
Sci Transl Med
, vol.2
-
-
Porter, F.D.1
Scherrer, D.E.2
Lanier, M.H.3
Langmade, S.J.4
Molugu, V.5
Gale, S.E.6
-
100
-
-
79959232858
-
A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma
-
Jiang X, Sidhu R, Porter FD, Yanjanin NM, Speak AO, te Vruchte DT, et al. A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma. J Lipid Res 2011;52:1435-45.
-
(2011)
J Lipid Res
, vol.52
, pp. 1435-1445
-
-
Jiang, X.1
Sidhu, R.2
Porter, F.D.3
Yanjanin, N.M.4
Speak, A.O.5
Te Vruchte, D.T.6
-
101
-
-
69049084375
-
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
-
Farez MF, Quintana FJ, Gandhi R, Izquierdo G, Lucas M, Weiner HL. Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat Immun 2009;10:958-64.
-
(2009)
Nat Immun
, vol.10
, pp. 958-964
-
-
Farez, M.F.1
Quintana, F.J.2
Gandhi, R.3
Izquierdo, G.4
Lucas, M.5
Weiner, H.L.6
-
102
-
-
78650905233
-
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fiction
-
Björkhem I, Lövgren-Sandblom A, Piehl F, Khademi M, Pettersson H, Leoni V, et al. High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: fact or fiction. J Lipid Res 2011;52:170-4.
-
(2011)
J Lipid Res
, vol.52
, pp. 170-174
-
-
Björkhem, I.1
Lövgren-Sandblom, A.2
Piehl, F.3
Khademi, M.4
Pettersson, H.5
Leoni, V.6
-
103
-
-
67649415324
-
CYP7B1 mutations in pure and complex forms of hereditary spastic paraplegia type 5
-
Goizet C, Boukhris A, Durr A, Beetz C, Truchetto J, Tesson C, et al. CYP7B1 mutations in pure and complex forms of hereditary spastic paraplegia type 5. Brain 2009;132:1589-600.
-
(2009)
Brain
, vol.132
, pp. 1589-1600
-
-
Goizet, C.1
Boukhris, A.2
Durr, A.3
Beetz, C.4
Truchetto, J.5
Tesson, C.6
-
104
-
-
64149091321
-
Analysis of CYP7B1 in non-consanguineous cases of hereditary spastic paraplegia
-
Schü le R, Brandt E, Karle KN, Tsaousidou M, Klebe S, Klimpe S, et al. Analysis of CYP7B1 in non-consanguineous cases of hereditary spastic paraplegia. Neurogenetics 2009;10:97-104.
-
(2009)
Neurogenetics
, vol.10
, pp. 97-104
-
-
Schü Le, R.1
Brandt, E.2
Karle, K.N.3
Tsaousidou, M.4
Klebe, S.5
Klimpe, S.6
-
105
-
-
40749142468
-
Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration
-
Tsaousidou MK, Ouahchi K, Warner TT, Yang Y, Simpson MA, Laing NG, et al. Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration. Am J Hum Genet 2008;82:510-5.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 510-515
-
-
Tsaousidou, M.K.1
Ouahchi, K.2
Warner, T.T.3
Yang, Y.4
Simpson, M.A.5
Laing, N.G.6
-
106
-
-
77950599782
-
Marked accumulation of 27-hydroxycholesterol inSPG5 patients with hereditary spastic paresis
-
Schü le R, Siddique T, Deng HX, Yang Y, Donkervoort S, Hansson M, et al. Marked accumulation of 27-hydroxycholesterol inSPG5 patients with hereditary spastic paresis. J Lipid Res 2010;51:819-23.
-
(2010)
J Lipid Res
, vol.51
, pp. 819-823
-
-
Schü Le, R.1
Siddique, T.2
Deng, H.X.3
Yang, Y.4
Donkervoort, S.5
Hansson, M.6
-
107
-
-
0141532288
-
Feedback regulation of bile acid synthesis in primary human hepatocytes: Evidence that CDCA is the strongest inhibitor
-
DOI 10.1053/jhep.2003.50394
-
Ellis E, Axelson M, Abrahamsson A, Eggertsen G, Thö rne A, Nowak G, et al. Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor. Hepatology 2003;38: 930-8. (Pubitemid 37221676)
-
(2003)
Hepatology
, vol.38
, Issue.4
, pp. 930-938
-
-
Ellis, E.1
Axelson, M.2
Abrahamsson, A.3
Eggertsen, G.4
Thorne, A.5
Nowak, G.6
Ericzon, B.-G.7
Bjorkhem, I.8
Einarsson, C.9
-
108
-
-
0023203074
-
On the possible use of the serum level of 7-hydroxycholesterol as a marker for increased activity of the cholesterol 7-hydroxylase in humans
-
Bjorkhem I, Reihner E, Angelin B, Ewerth S, Akerlund JE, Einarsson K. On the possible use of the serum level of 7 alpha-hydroxycholesterol as a marker for increased activity of the cholesterol 7 alpha-hydroxylase in humans. J Lipid Res 1987;28:889-94. (Pubitemid 17143370)
-
(1987)
Journal of Lipid Research
, vol.28
, Issue.8
, pp. 889-894
-
-
Bjorkhem, I.1
Reihner, E.2
Angelin, B.3
Ewerth, S.4
Akerlund, J.-E.5
Einarsson, K.6
-
109
-
-
34248210553
-
On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis
-
DOI 10.1194/jlr.M700027-JLR200
-
Panzenboeck U, Andersson U, Hansson M, Sattler W, Meaney S, Björkhem I. On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis. J Lipid Res 2007;48:1167-74. (Pubitemid 46708684)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.5
, pp. 1167-1174
-
-
Panzenboeck, U.1
Andersson, U.2
Hansson, M.3
Sattler, W.4
Meaney, S.5
Bjorkhem, I.6
-
110
-
-
0037213345
-
Serum cholesterol, precursors and metabolites and cognitive performance in an aging population
-
DOI 10.1016/S0197-4580(02)00061-1, PII S0197458002000611
-
Teunissen CE, De Vente J, von Bergmann K, Bosma H, van Boxtel MP, De Bruijn C, et al. Serum cholesterol, precursors and metabolites and cognitive performance in an aging population. Neurobiol Aging 2003;24:147-55. (Pubitemid 35454151)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.1
, pp. 147-155
-
-
Teunissen, C.E.1
De Vente, J.2
Von Bergmann, K.3
Bosma, H.4
Van Boxtel, M.P.J.5
De Bruijn, C.6
Jolles, J.7
Steinbusch, H.W.M.8
Lutjohann, D.9
-
111
-
-
84855808674
-
The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline
-
van den Kommer TN, Dik MG, Comijs HC, Lü tjohann D, Lips P, Jonker C, et al. The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline. Neurobiol Aging 2012;33:17-28.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 17-28
-
-
Van Den Kommer, T.N.1
Dik, M.G.2
Comijs, H.C.3
Lü Tjohann, D.4
Lips, P.5
Jonker, C.6
-
112
-
-
61649126681
-
Oxysterols as markers of neurological disease a review
-
Leoni V. Oxysterols as markers of neurological disease-a review. Scand J Clin Lab Invest 2009;69:22-5.
-
(2009)
Scand J Clin Lab Invest
, vol.69
, pp. 22-25
-
-
Leoni, V.1
-
113
-
-
1642525647
-
Diagnostic use of cerebral and extracerebral oxysterols
-
DOI 10.1515/CCLM.2004.034
-
Leoni V, Masterman T, Mousavi FS, Wretlind B, Wahlund LO, Diczfalusy U, et al. Diagnostic use of cerebral and extracerebral oxysterols. Clin Chem Lab Med 2004;42:186-91. (Pubitemid 38401447)
-
(2004)
Clinical Chemistry and Laboratory Medicine
, vol.42
, Issue.2
, pp. 186-191
-
-
Leoni, V.1
Masterman, T.2
Mousavi, F.S.3
Wretlind, B.4
Wahlund, L.-O.5
Diczfalusy, U.6
Hillert, J.7
Bjorkhem, I.8
-
114
-
-
33644752889
-
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment?
-
DOI 10.1016/j.neulet.2005.11.046, PII S0304394005013741
-
Leoni V, Shafaati M, Salomon A, Kivipelto M, Björkhem I, Wahlund LO. Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment. Neurosci Lett 2006;397:83-7. (Pubitemid 43340464)
-
(2006)
Neuroscience Letters
, vol.397
, Issue.1-2
, pp. 83-87
-
-
Leoni, V.1
Shafaati, M.2
Salomon, A.3
Kivipelto, M.4
Bjorkhem, I.5
Wahlund, L.-O.6
-
115
-
-
34548634369
-
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders
-
DOI 10.1016/j.neulet.2007.08.014, PII S0304394007008580
-
Shafaati M, Solomon A, Kivipelto M, Björkhem I, Leoni V. Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders. Neurosci Lett 2007;425:78-82. (Pubitemid 47410361)
-
(2007)
Neuroscience Letters
, vol.425
, Issue.2
, pp. 78-82
-
-
Shafaati, M.1
Solomon, A.2
Kivipelto, M.3
Bjorkhem, I.4
Leoni, V.5
-
116
-
-
0036138648
-
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia
-
DOI 10.1016/S0022-3956(01)00050-4, PII S0022395601000504
-
Papassotiropoulos A, Lü tjohann D, Bagli M, Locatelli S, Jessen F, Buschfort R, et al. 24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. J Psychiatr Res 2002;36:27-32. (Pubitemid 34037845)
-
(2002)
Journal of Psychiatric Research
, vol.36
, Issue.1
, pp. 27-32
-
-
Papassotiropoulos, A.1
Lutjohann, D.2
Bagli, M.3
Locatelli, S.4
Jessen, F.5
Buschfort, R.6
Ptok, U.7
Bjorkhem, I.8
Von Bergmann, K.9
Heun, R.10
-
117
-
-
0037052771
-
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls
-
DOI 10.1016/S0304-3940(02)00164-7, PII S0304394002001647
-
Schönknecht P, Lü tjohann D, Pantel J, Bardenheuer H, Hartmann T, von Bergmann K, et al. Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls. Neurosci Lett 2002;324:83-5. (Pubitemid 34442684)
-
(2002)
Neuroscience Letters
, vol.324
, Issue.1
, pp. 83-85
-
-
Schonknecht, P.1
Lutjohann, D.2
Pantel, J.3
Bardenheuer, H.4
Hartmann, T.5
Von Bergmann, K.6
Beyreuther, K.7
Schroder, J.8
-
118
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic BV. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008;57:178-201.
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
119
-
-
0035921150
-
Dynamics of brain-derived proteins in cerebrospinal fluid
-
DOI 10.1016/S0009-8981(01)00573-3, PII S0009898101005733
-
Reiber H. Dynamics of brain-specific protein in cerebrospinal fluid. Clin Chim Acta 2001;310:173-86. (Pubitemid 32728347)
-
(2001)
Clinica Chimica Acta
, vol.310
, Issue.2
, pp. 173-186
-
-
Reiber, H.1
-
120
-
-
0025342659
-
Heterogeneity of blood-brain barrier changes in multiple sclerosis: An MRI study with gadolinium-DTPA enhancement
-
Kermode AG, Tofts PS, Thompson AJ, MacManus DG, Rudge P, Kendall BE, et al. Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement. Neurology 1990;40: 229-35. (Pubitemid 20099429)
-
(1990)
Neurology
, vol.40
, Issue.2
, pp. 229-235
-
-
Kermode, A.G.1
Tofts, P.S.2
Thompson, A.J.3
MacManus, D.G.4
Rudge, P.5
Kendall, B.E.6
Kingsley, D.P.E.7
Moseley, I.F.8
Du Boulay, E.P.G.H.9
McDonald, W.I.10
-
121
-
-
58549098084
-
Blood-brain barrier: Ageing and microvascular disease-systematic review and meta-analysis
-
Farrall AJ, Wardlaw JM. Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis. Neurobiol Aging 2009; 30:337-52.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 337-352
-
-
Farrall, A.J.1
Wardlaw, J.M.2
-
122
-
-
80051664950
-
The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease
-
Vanmierlo T, Popp J, Kolsch H, Friedrichs S, Jessen F, Stoffel-Wagner B, et al. The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease. Acta psychiatric Scandinavica 2011;124:184-92.
-
(2011)
Acta Psychiatric Scandinavica
, vol.124
, pp. 184-192
-
-
Vanmierlo, T.1
Popp, J.2
Kolsch, H.3
Friedrichs, S.4
Jessen, F.5
Stoffel-Wagner, B.6
-
123
-
-
79960756506
-
Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease
-
Chalbot S, Zetterberg H, Blennow K, Fladby T, Andreasen N, Grundke-Iqbal I, et al. Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease. J Alzheimers Dis 2011;25:505-15.
-
(2011)
J Alzheimers Dis
, vol.25
, pp. 505-515
-
-
Chalbot, S.1
Zetterberg, H.2
Blennow, K.3
Fladby, T.4
Andreasen, N.5
Grundke-Iqbal, I.6
-
124
-
-
0029609264
-
Tau Protein in cerebrospinal fluid: A biochemical marker for axonal degeneration in Alzheimer disease?
-
Blennow K, Wallin A, Agren H, Spenger C, Siegfried J, Vanmechelen E. Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease. Mol Chem Neuropathol 1995;26:231-45. (Pubitemid 26002016)
-
(1995)
Molecular and Chemical Neuropathology
, vol.26
, Issue.3
, pp. 231-245
-
-
Blennow, K.1
Wallin, A.2
Agren, H.3
Spenger, C.4
Siegfried, J.5
Vanmechelen, E.6
-
125
-
-
0037457354
-
Cerebrospinal fluid biomarkers for disease stage and intensity in cognitively impaired patients
-
DOI 10.1016/S0304-3940(02)01483-0
-
Wahlund LO, Blennow K. Cerebrospinal fluid biomarkers for disease stage and intensity in cognitively impaired patients. Neurosci Lett 2003;339: 99-102. (Pubitemid 36254786)
-
(2003)
Neuroscience Letters
, vol.339
, Issue.2
, pp. 99-102
-
-
Wahlund, L.-O.1
Blennow, K.2
-
127
-
-
0037066123
-
Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia
-
Jack Jr CR, Dickson DW, Parisi JE, Xu YC, Cha RH, O'Brien PC, et al. Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia. Neurology 2002;58:750-7. (Pubitemid 34211554)
-
(2002)
Neurology
, vol.58
, Issue.5
, pp. 750-757
-
-
Jack Jr., C.R.1
Dickson, D.W.2
Parisi, J.E.3
Xu, Y.C.4
Cha, R.H.5
O'Brien, P.C.6
Edland, S.D.7
Smith, G.E.8
Boeve, B.F.9
Tangalos, E.G.10
Kokmen, E.11
Petersen, R.C.12
-
128
-
-
39049173162
-
Neuropathological basis of magnetic resonance images in aging and dementia
-
DOI 10.1002/ana.21296
-
Jagust WJ, Zheng L, Harvey DJ, Mack WJ, Vinters HV, Weiner MW, et al. Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol 2008;63:72-80. (Pubitemid 351240553)
-
(2008)
Annals of Neurology
, vol.63
, Issue.1
, pp. 72-80
-
-
Jagust, W.J.1
Zheng, L.2
Harvey, D.J.3
Mack, W.J.4
Vinters, H.V.5
Weiner, M.W.6
Ellis, W.G.7
Zarow, C.8
Mungas, D.9
Reed, B.R.10
Kramer, J.H.11
Schuff, N.12
DeCarli, C.13
Chui, H.C.14
-
129
-
-
47949121047
-
Antemortem MRI based STructural Abnormality iNDex (STAND)-scores correlate with postmortem Braak neurofibrillary tangle stage
-
Vemuri P, Whitwell JL, Kantarci K, Josephs KA, Parisi JE, Shiung MS, et al. Antemortem MRI based STructural Abnormality iNDex (STAND)-scores correlate with postmortem Braak neurofibrillary tangle stage. Neuroimage 2008;42:559-67.
-
(2008)
Neuroimage
, vol.42
, pp. 559-567
-
-
Vemuri, P.1
Whitwell, J.L.2
Kantarci, K.3
Josephs, K.A.4
Parisi, J.E.5
Shiung, M.S.6
-
130
-
-
68249090572
-
MRI and CSF biomarkers in normal, MCI, and AD subjects: Diagnostic discrimination and cognitive correlations
-
Vemuri P, Wiste HJ, Weigand SD, Shaw LM, Trojanowski JQ, Weiner MW, et al. MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations. Neurology 2009;73:287-93.
-
(2009)
Neurology
, vol.73
, pp. 287-293
-
-
Vemuri, P.1
Wiste, H.J.2
Weigand, S.D.3
Shaw, L.M.4
Trojanowski, J.Q.5
Weiner, M.W.6
-
131
-
-
0033559412
-
Expression of human apolipoprotein E reduces amyloid- deposition in a mouse model of Alzheimer's disease
-
Holtzman DM, Bales KR, Wu S, Bhat P, Parsadanian M, Fagan AM, et al. Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease. J Clin Invest 1999;103:R15-21. (Pubitemid 29152639)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.6
-
-
Holtzman, D.M.1
Bales, K.R.2
Wu, S.3
Bhat, P.4
Parsadanian, M.5
Fagan, A.M.6
Chang, L.K.7
Sun, Y.8
Paul, S.M.9
-
132
-
-
0141814636
-
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
-
DOI 10.1073/pnas.1434398100
-
Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, et al. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease- like neurodegeneration and behavioral deficits in transgenic mice. Proc Natl Acad Sci USA 2003;100:10966-71. (Pubitemid 37140136)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.19
, pp. 10966-10971
-
-
Harris, F.M.1
Brecht, W.J.2
Xu, Q.3
Tesseur, I.4
Kekonius, L.5
Wyss-Coray, T.6
Fish, J.D.7
Masliah, E.8
Hopkins, P.C.9
Scearce-Levie, K.10
Weisgraber, K.H.11
Mucke, L.12
Mahley, R.W.13
Huang, Y.14
-
133
-
-
0033889344
-
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
-
Tesseur I, Van Dorpe J, Spittaels K, Van den Haute C, Moechars C, Van Leuven F. Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice. Am J Pathol 2000;156:951-64. (Pubitemid 30626953)
-
(2000)
American Journal of Pathology
, vol.156
, Issue.3
, pp. 951-964
-
-
Tesseur, I.1
Van Dorpe, J.2
Spittaels, K.3
Van Den Haute, C.4
Moechars, D.5
Van Leuven, F.6
-
134
-
-
2942536666
-
Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
-
Tiraboschi P, Hansen LA, Masliah E, Alford M, Thal LJ, Corey-Bloom J. Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology 2004;62:1977-83. (Pubitemid 38738207)
-
(2004)
Neurology
, vol.62
, Issue.11
, pp. 1977-1983
-
-
Tiraboschi, P.1
Hansen, L.A.2
Masliah, E.3
Alford, M.4
Thal, L.J.5
Corey-Bloom, J.6
-
135
-
-
67650094927
-
Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age
-
Kok E, Haikonen S, Luoto T, Huhtala H, Goebeler S, Haapasalo H, et al. Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann Neurol 2009;65:650-7.
-
(2009)
Ann Neurol
, vol.65
, pp. 650-657
-
-
Kok, E.1
Haikonen, S.2
Luoto, T.3
Huhtala, H.4
Goebeler, S.5
Haapasalo, H.6
-
136
-
-
33744991531
-
Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes
-
DOI 10.1016/j.biochi.2005.10.007, PII S0300908405002427
-
Rapp A, Gmeiner B, Huttinger M. Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes. Biochimie 2006;88:473-83. (Pubitemid 43867898)
-
(2006)
Biochimie
, vol.88
, Issue.5
, pp. 473-483
-
-
Rapp, A.1
Gmeiner, B.2
Huttinger, M.3
-
137
-
-
0037119427
-
Apolipoprotein e (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice
-
Gong JS, Kobayashi M, Hayashi H, Zou K, Sawamura N, Fujita SC, et al. Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice. J Biol Chem 2002;277:29919-26.
-
(2002)
J Biol Chem
, vol.277
, pp. 29919-29926
-
-
Gong, J.S.1
Kobayashi, M.2
Hayashi, H.3
Zou, K.4
Sawamura, N.5
Fujita, S.C.6
-
138
-
-
33947205478
-
The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins
-
DOI 10.1021/bi602407r
-
Vedhachalam C, Narayanaswami V, Neto N, Forte TM, Phillips MC, Lund-Katz S, et al. The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins. Biochemistry 2007;46: 2583-93. (Pubitemid 46417902)
-
(2007)
Biochemistry
, vol.46
, Issue.10
, pp. 2583-2593
-
-
Vedhachalam, C.1
Narayanaswami, V.2
Neto, N.3
Forte, T.M.4
Phillips, M.C.5
Lund-Katz, S.6
Bielicki, J.K.7
-
139
-
-
79952812955
-
The effect of apolipoprotein e (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease
-
Leoni V. The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease. Clin Chem Lab Med 2011;49:375-83.
-
(2011)
Clin Chem Lab Med
, vol.49
, pp. 375-383
-
-
Leoni, V.1
-
140
-
-
77956411745
-
Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers
-
Serrano-Pozo A, Vega GL, Lü tjohann D, Locascio JJ, Tennis MK, Deng A, et al. Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers. Alzheimer Dis Assoc Disord 2010;24:220-6.
-
(2010)
Alzheimer Dis Assoc Disord
, vol.24
, pp. 220-226
-
-
Serrano-Pozo, A.1
Vega, G.L.2
Lü Tjohann, D.3
Locascio, J.J.4
Tennis, M.K.5
Deng, A.6
-
141
-
-
34047250984
-
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-peptide generation
-
DOI 10.1074/jbc.M607831200
-
Kim WS, Rahmanto AS, Kamili A, Rye KA, Guillemin GJ, Gelissen IC, et al. Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation. J Biol Chem 2007;282:2851-61. (Pubitemid 47084333)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.5
, pp. 2851-2861
-
-
Kim, W.S.1
Rahmanto, A.S.2
Kamili, A.3
Rye, K.-A.4
Guillemin, G.J.5
Gelissen, I.C.6
Jessup, W.7
Hill, A.F.8
Garner, B.9
-
142
-
-
68249134074
-
The role of apolipoprotein e in Alzheimer's disease
-
Kim J, Basak JM, Holtzman DM. The role of apolipoprotein E in Alzheimer's disease. Neuron 2009;63:287-303.
-
(2009)
Neuron
, vol.63
, pp. 287-303
-
-
Kim, J.1
Basak, J.M.2
Holtzman, D.M.3
-
143
-
-
0033528279
-
The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells
-
DOI 10.1016/S0006-8993(98)01274-8, PII S0006899398012748
-
Kö lsch H, Lü tjohann D, Tulke A, Björkhem I, Rao ML. The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells. Brain Res 1999;818:171-5. (Pubitemid 29227299)
-
(1999)
Brain Research
, vol.818
, Issue.1
, pp. 171-175
-
-
Kolsch, H.1
Lutjohann, D.2
Tulke, A.3
Bjorkhem, I.4
Rao, M.L.5
-
144
-
-
79960111702
-
24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis
-
Yamanaka K, Saito Y, Yamamori T, Urano Y, Noguchi N. 24(S)- hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis. J Biol Chem 2011;286:24666-73.
-
(2011)
J Biol Chem
, vol.286
, pp. 24666-24673
-
-
Yamanaka, K.1
Saito, Y.2
Yamamori, T.3
Urano, Y.4
Noguchi, N.5
-
145
-
-
79955955895
-
Interaction between24-hydroxycholesterol, oxidative stress, and amyloid-b in amplifying neuronal damage in Alzheimer's disease: Three partners in crime
-
Gamba P, Leonarduzzi G, Tamagno E, Guglielmotto M, Testa G, Sottero B, et al. Interaction between24-hydroxycholesterol, oxidative stress, and amyloid-b in amplifying neuronal damage in Alzheimer's disease: three partners in crime.
-
(2011)
Aging Cell
, vol.10
, pp. 403-417
-
-
Gamba, P.1
Leonarduzzi, G.2
Tamagno, E.3
Guglielmotto, M.4
Testa, G.5
Sottero, B.6
-
146
-
-
65349164191
-
Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals
-
Koschack J, Lü tjohann D, Schmidt-Samoa C, Irle E. Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals. Neurobiol Aging 2009;30:898-902.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 898-902
-
-
Koschack, J.1
Lü Tjohann, D.2
Schmidt-Samoa, C.3
Irle, E.4
-
147
-
-
0004821712
-
Plasma 24S-hydroxycholesterol: A peripheral indicator of neuronal degen- eration and potential state marker for Alzheimer's disease
-
Papassotiropoulos A, Lü tjohann D, Bagli M, Locatelli S, Jessen F, Rao ML, et al. Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degen- eration and potential state marker for Alzheimer's disease. Neuroreport 2000;11:1959-62.
-
(2000)
Neuroreport
, vol.11
, pp. 1959-1962
-
-
Papassotiropoulos, A.1
Lü Tjohann, D.2
Bagli, M.3
Locatelli, S.4
Jessen, F.5
Rao, M.L.6
-
148
-
-
78650475565
-
Vitamin e and enzymatic/oxidative stress-driven oxysterols in amnestic mild cognitive impairment subtypes and Alzheimer's disease
-
Iuliano L, Monticolo R, Straface G, Spoletini I, Gianni W, Caltagirone C, et al. Vitamin E and enzymatic/oxidative stress-driven oxysterols in amnestic mild cognitive impairment subtypes and Alzheimer's disease. J Alzheimers Dis 2010;21:1383-92.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 1383-1392
-
-
Iuliano, L.1
Monticolo, R.2
Straface, G.3
Spoletini, I.4
Gianni, W.5
Caltagirone, C.6
-
149
-
-
45849100113
-
Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury
-
DOI 10.1080/02699050802196037, PII 794216687
-
Weiner MF, Vega GL, Diaz-Arrastia R, Moore C, Madden C, Hudak A. Lütjohann D. Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury. Brain Inj 2008;22:611-5. (Pubitemid 351877856)
-
(2008)
Brain Injury
, vol.22
, Issue.7-8
, pp. 611-615
-
-
Weiner, M.F.1
Vega, G.L.2
Diaz-Arrastia, R.3
Moore, C.4
Madden, C.5
Hudak, A.6
Lutjohann, D.7
-
150
-
-
84858285697
-
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations
-
Leoni V, Strittmatter L, Zorzi G, Zibordi F, Dusi S, Garavaglia B, et al. Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations. Mol Genet Metab 2012;105:463-71.
-
(2012)
Mol Genet Metab
, vol.105
, pp. 463-471
-
-
Leoni, V.1
Strittmatter, L.2
Zorzi, G.3
Zibordi, F.4
Dusi, S.5
Garavaglia, B.6
|