메뉴 건너뛰기




Volumn 65, Issue 6, 2009, Pages 650-657

Apolipoprotein E-dependent accumulation of alzheimer disease-related lesions begins in middle age

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; APOLIPOPROTEIN E4; SILVER;

EID: 67650094927     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.21696     Document Type: Article
Times cited : (244)

References (39)
  • 1
    • 67650037203 scopus 로고    scopus 로고
    • O'Brien J, Ames D, Burns A. Dementia. London, UK: Arnold Cop; 2000.
    • O'Brien J, Ames D, Burns A. Dementia. London, UK: Arnold Cop; 2000.
  • 2
    • 0242576265 scopus 로고    scopus 로고
    • Atherosclerosis and neurodegeneration: Unexpected conspirators in alzheimer's dementia
    • Iadecola C. Atherosclerosis and neurodegeneration: unexpected conspirators in alzheimer's dementia. Arterioscler Thromb Vasc Biol 2003;23:1951-1953.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1951-1953
    • Iadecola, C.1
  • 3
    • 0028362458 scopus 로고
    • A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
    • Braak E, Braak H, Mandelkow EM. A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol 1994;87:554-567.
    • (1994) Acta Neuropathol , vol.87 , pp. 554-567
    • Braak, E.1    Braak, H.2    Mandelkow, E.M.3
  • 4
    • 0030805991 scopus 로고    scopus 로고
    • Frequency of stages of Alzheimer-related lesions in different age categories
    • Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging 1997;18:351-357.
    • (1997) Neurobiol Aging , vol.18 , pp. 351-357
    • Braak, H.1    Braak, E.2
  • 5
    • 12544259479 scopus 로고    scopus 로고
    • APOE genotype and cognitive decline in a middle-aged cohort
    • Blair CK, Folsom AR, Knopman DS, et al. APOE genotype and cognitive decline in a middle-aged cohort. Neurology 2005;64:268-276.
    • (2005) Neurology , vol.64 , pp. 268-276
    • Blair, C.K.1    Folsom, A.R.2    Knopman, D.S.3
  • 7
    • 0035915621 scopus 로고    scopus 로고
    • Pathological correlates of late-onset dementia in a multi-centre, community-based population in England and Wales
    • The Neuropathological Group of the Medical Research Council Cognitive Function and Ageing Study CFAS
    • The Neuropathological Group of the Medical Research Council Cognitive Function and Ageing Study (CFAS). Pathological correlates of late-onset dementia in a multi-centre, community-based population in England and Wales. Lancet 2001;357:169-175.
    • (2001) Lancet , vol.357 , pp. 169-175
  • 8
    • 0034575124 scopus 로고    scopus 로고
    • Apolipoprotein E: Far more than a lipid transport protein
    • Mahley RW, Rall SC Jr. Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet 2000;1:507-537.
    • (2000) Annu Rev Genomics Hum Genet , vol.1 , pp. 507-537
    • Mahley, R.W.1    Rall Jr, S.C.2
  • 9
    • 20444395466 scopus 로고    scopus 로고
    • Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism
    • Reiman EM, Chen K, Alexander GE, et al. Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism. Proc Natl Acad Sci USA 2005;102:8299-8302.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8299-8302
    • Reiman, E.M.1    Chen, K.2    Alexander, G.E.3
  • 10
    • 0037031125 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease
    • Kivipelto M, Helkala EL, Laakso MP, et al. Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med 2002;137:149-155.
    • (2002) Ann Intern Med , vol.137 , pp. 149-155
    • Kivipelto, M.1    Helkala, E.L.2    Laakso, M.P.3
  • 11
    • 0028026997 scopus 로고    scopus 로고
    • van Duijn CM, de Knijff P, Cruts M, et al. Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease. Nat Genet 1994;7:74-78.
    • van Duijn CM, de Knijff P, Cruts M, et al. Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease. Nat Genet 1994;7:74-78.
  • 12
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease
    • Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. JAMA 1997;278:1349-1356.
    • (1997) JAMA , vol.278 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3
  • 13
    • 0037426289 scopus 로고    scopus 로고
    • The role of APOE-epsilon4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging
    • Bretsky P, Guralnik JM, Launer L, et al. The role of APOE-epsilon4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging. Neurology 2003;60:1077-1081.
    • (2003) Neurology , vol.60 , pp. 1077-1081
    • Bretsky, P.1    Guralnik, J.M.2    Launer, L.3
  • 14
    • 0034974216 scopus 로고    scopus 로고
    • Memory performance in healthy elderly without Alzheimer's disease: Effects of time and apolipoprotein-E
    • Mayeux R, Small SA, Tang M, et al. Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein-E. Neurobiol Aging 2001;22:683-689.
    • (2001) Neurobiol Aging , vol.22 , pp. 683-689
    • Mayeux, R.1    Small, S.A.2    Tang, M.3
  • 15
    • 0035849490 scopus 로고    scopus 로고
    • Memory decline in healthy older people: Implications for identifying mild cognitive impairment
    • Collie A, Maruff P, Shafiq-Antonacci R, et al. Memory decline in healthy older people: implications for identifying mild cognitive impairment. Neurology 2001;56:1533-1538.
    • (2001) Neurology , vol.56 , pp. 1533-1538
    • Collie, A.1    Maruff, P.2    Shafiq-Antonacci, R.3
  • 16
    • 0029118904 scopus 로고
    • Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology 1995;45:1323-1328.
    • (1995) Neurology , vol.45 , pp. 1323-1328
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 17
    • 0035954350 scopus 로고    scopus 로고
    • Prevalence of Alzheimer's disease in very elderly people: A prospective neuropathological study
    • Polvikoski T, Sulkava R, Myllykangas L, et al. Prevalence of Alzheimer's disease in very elderly people: a prospective neuropathological study. Neurology 2001;56:1690-1696.
    • (2001) Neurology , vol.56 , pp. 1690-1696
    • Polvikoski, T.1    Sulkava, R.2    Myllykangas, L.3
  • 18
    • 0025908356 scopus 로고
    • The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, et al. The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 19
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • Kononen J, Bubendorf L, Kallioniemi A, et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 1998;4:844-847.
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 21
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
    • Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545-548.
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 22
    • 0030050286 scopus 로고    scopus 로고
    • Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease
    • Gomez-Isla T, West HL, Rebeck GW, et al. Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease. Ann Neurol 1996;39:62-70.
    • (1996) Ann Neurol , vol.39 , pp. 62-70
    • Gomez-Isla, T.1    West, H.L.2    Rebeck, G.W.3
  • 23
    • 0034663341 scopus 로고    scopus 로고
    • Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology
    • Baum L, Chen L, Ng HK, Pang CP. Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology. Microsc Res Tech 2000;50:278-281.
    • (2000) Microsc Res Tech , vol.50 , pp. 278-281
    • Baum, L.1    Chen, L.2    Ng, H.K.3    Pang, C.P.4
  • 24
    • 32044464716 scopus 로고    scopus 로고
    • Incidence of dementia in very elderly individuals: A clinical, neuropathological and molecular genetic study
    • Polvikoski T, Sulkava R, Rastas S, et al. Incidence of dementia in very elderly individuals: a clinical, neuropathological and molecular genetic study. Neuroepidemiology 2006;26:76-82.
    • (2006) Neuroepidemiology , vol.26 , pp. 76-82
    • Polvikoski, T.1    Sulkava, R.2    Rastas, S.3
  • 25
    • 0031902936 scopus 로고    scopus 로고
    • Polymorphism in senile dementia of the Alzheimer type from a viewpoint of senile plaque formation
    • Yamaguchi H. Polymorphism in senile dementia of the Alzheimer type from a viewpoint of senile plaque formation. Acta Neuropathol 1998;18:98-102.
    • (1998) Acta Neuropathol , vol.18 , pp. 98-102
    • Yamaguchi, H.1
  • 26
    • 0031664361 scopus 로고    scopus 로고
    • High frequency of apolipoprotein E e4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes
    • Ghebremedhin E, Schultz C, Braak E, Braak H. High frequency of apolipoprotein E e4 allele in young individuals with very mild Alzheimer's disease-related neurofibrillary changes. Exp Neurol 1998;153:152-155.
    • (1998) Exp Neurol , vol.153 , pp. 152-155
    • Ghebremedhin, E.1    Schultz, C.2    Braak, E.3    Braak, H.4
  • 27
    • 33846089505 scopus 로고    scopus 로고
    • A review of genome mutation and Alzheimer's disease
    • Thomas P, Fenech M. A review of genome mutation and Alzheimer's disease. Mutagenesis 2007;22:15-33.
    • (2007) Mutagenesis , vol.22 , pp. 15-33
    • Thomas, P.1    Fenech, M.2
  • 28
    • 0036593191 scopus 로고    scopus 로고
    • Eostrogen as a neuroprotective hormone
    • Behl C. Eostrogen as a neuroprotective hormone. Nat Rev Neurosci 2002;3:433-442.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 433-442
    • Behl, C.1
  • 29
    • 2442665411 scopus 로고    scopus 로고
    • Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: Variation by age and sex
    • Qiu C, Kivipelto M, Aguero-Torres H, et al. Risk and protective effects of the APOE gene towards Alzheimer's disease in the Kungsholmen project: variation by age and sex. J Neurol Neurosurg Psychiatry 2004;75:828-833.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 828-833
    • Qiu, C.1    Kivipelto, M.2    Aguero-Torres, H.3
  • 30
    • 0036596873 scopus 로고    scopus 로고
    • Vascular risk factors, ApoE ε4 allele, and gender and the risk of Alzheimer's disease: Perspectives on prevention
    • Kivipelto M, Helkala EL, Nissinen A, et al. Vascular risk factors, ApoE ε4 allele, and gender and the risk of Alzheimer's disease: perspectives on prevention. Drug Dev Res 2002;56:85-94.
    • (2002) Drug Dev Res , vol.56 , pp. 85-94
    • Kivipelto, M.1    Helkala, E.L.2    Nissinen, A.3
  • 31
    • 0028946248 scopus 로고
    • Apolipoprotein E, serum lipids, myocardial infarction and severity of angiographically verified coronary artery disease in men and women
    • Lehtinen S, Lehtimaki T, Sisto T, et al. Apolipoprotein E, serum lipids, myocardial infarction and severity of angiographically verified coronary artery disease in men and women. Atherosclerosis 1995;114:83-91.
    • (1995) Atherosclerosis , vol.114 , pp. 83-91
    • Lehtinen, S.1    Lehtimaki, T.2    Sisto, T.3
  • 32
    • 0030002516 scopus 로고    scopus 로고
    • Increased density of senile plaques (SP), but not neurofibrillary tangles (NFT), in nondemented individuals with the apolipoprotein E4 allele: Comparison to confirmed Alzheimer's disease patients
    • Sparks DL, Scheff SW, Liu H, et al. Increased density of senile plaques (SP), but not neurofibrillary tangles (NFT), in nondemented individuals with the apolipoprotein E4 allele: comparison to confirmed Alzheimer's disease patients. J Neurol Sci 1996;138:97-104.
    • (1996) J Neurol Sci , vol.138 , pp. 97-104
    • Sparks, D.L.1    Scheff, S.W.2    Liu, H.3
  • 33
    • 0035954324 scopus 로고    scopus 로고
    • Gender and age modify the association between APOE and AD-related neuropathology
    • Ghebremedhin E, Schultz C, Thal DR, et al. Gender and age modify the association between APOE and AD-related neuropathology. Neurology 2001;56:1696-1701.
    • (2001) Neurology , vol.56 , pp. 1696-1701
    • Ghebremedhin, E.1    Schultz, C.2    Thal, D.R.3
  • 34
    • 14444285507 scopus 로고    scopus 로고
    • Clinicopathologic studies in cognitively healthy aging and Alzheimer disease: Relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype
    • Berg L, McKeel DW, Miller JP, et al. Clinicopathologic studies in cognitively healthy aging and Alzheimer disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 1998;55:326-335.
    • (1998) Arch Neurol , vol.55 , pp. 326-335
    • Berg, L.1    McKeel, D.W.2    Miller, J.P.3
  • 35
    • 0028305380 scopus 로고    scopus 로고
    • Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet 1994;7:180-184.
    • Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet 1994;7:180-184.
  • 36
    • 2942536666 scopus 로고    scopus 로고
    • Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
    • Tiraboschi P, Hansen LA, Masliah E, et al. Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease. Neurology 2004;62:1977-1983.
    • (2004) Neurology , vol.62 , pp. 1977-1983
    • Tiraboschi, P.1    Hansen, L.A.2    Masliah, E.3
  • 37
    • 33746922758 scopus 로고    scopus 로고
    • Interlaboratory comparison of assessments of Alzheimer disease-related lesions: A study of the BrainNet Europe Consortium
    • Alafuzoff I, Pikkarainen M, Al-Sarraj S, et al. Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe Consortium. J Neuropathol Exp Neurol 2006;65:740-757.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 740-757
    • Alafuzoff, I.1    Pikkarainen, M.2    Al-Sarraj, S.3
  • 38
    • 26444463825 scopus 로고    scopus 로고
    • Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    • Kivipelto M, Ngandu T, Fratiglioni L, et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol 2005;62:1556-1560.
    • (2005) Arch Neurol , vol.62 , pp. 1556-1560
    • Kivipelto, M.1    Ngandu, T.2    Fratiglioni, L.3
  • 39
    • 0141819900 scopus 로고    scopus 로고
    • Vascular factors in Alzheimer's disease
    • Kalaria RN. Vascular factors in Alzheimer's disease. Int Psychogeriatr 2003;15:47-52.
    • (2003) Int Psychogeriatr , vol.15 , pp. 47-52
    • Kalaria, R.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.