ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

FASEB Journal

Volumn 22, Issue 4, 2008, Pages 1073-1082

  Wang, Nan ^a   Yvan Charvet, Laurent ^a   Lütjohann, Dieter ^b   Mulder, Monique ^c   Vanmierlo, Tim ^c   Kim, Tae Wan ^a   Tall, Alan R ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF BONN   (Germany)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Abcg1; Abcg4; Apolipoprotein E; Astrocyte; Efflux; Neuron

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G1; APOLIPOPROTEIN E; ATP BINDING CASSETTE TRANSPORTER G4; CHOLESTEROL; DESMOSTEROL; HIGH DENSITY LIPOPROTEIN; LANOSTEROL; LATHOSTEROL; LIVER X RECEPTOR; STEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN METABOLISM; BRAIN NERVE CELL; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VIVO STUDY; KNOCKOUT MOUSE; LIPID BRAIN LEVEL; LIPID TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STEROL METABOLISM;

ANIMALS; APOLIPOPROTEINS E; ASTROCYTES; ATP-BINDING CASSETTE TRANSPORTERS; BRAIN; CHOLESTEROL; DESMOSTEROL; DNA-BINDING PROTEINS; HUMANS; LIPOPROTEINS; LIPOPROTEINS, HDL; MICE; MICE, TRANSGENIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

MUS;

EID: 42049122331     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-9944com     Document Type: Article

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