-
1
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG, Wong CW (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cere-brovascular amyloid protein. Biochem Biophys Res Commun 120, 885-890. (Pubitemid 14104991)
-
(1984)
Biochemical and Biophysical Research Communications
, vol.120
, Issue.3
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
2
-
-
0027333557
-
Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide
-
Haass C, Selkoe DJ (1993) Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell 75, 1039-1042.
-
(1993)
Cell
, vol.75
, pp. 1039-1042
-
-
Haass, C.1
Selkoe, D.J.2
-
3
-
-
0034049944
-
Proteolytic processing and cell biological functions of the amyloid precursor protein
-
De Strooper B, Annaert W (2000) Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci 113 (Pt 11), 1857-1870. (Pubitemid 30386490)
-
(2000)
Journal of Cell Science
, vol.113
, Issue.11
, pp. 1857-1870
-
-
De Strooper, B.1
Annaert, W.2
-
4
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Pre-senilin generate an active gamma-Secretase complex
-
De Strooper B (2003) Aph-1, Pen-2, and Nicastrin with Pre-senilin generate an active gamma-Secretase complex. Neuron 38, 9-12.
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
5
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy JA, Higgins GA (1992) Alzheimer's disease: the amyloid cascade hypothesis. Science 256, 184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
6
-
-
0034928074
-
sw mice
-
Mori T, Paris D, Town T, Rojiani AM, Sparks DL, Delledonne A, Crawford F, Abdullah LI, Humphrey JA, Dickson DW, Mullan MJ (2001) Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP (SW) mice. J Neuropathol Exp Neurol 60, 778-785. (Pubitemid 32678258)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.8
, pp. 778-785
-
-
Mori, T.1
Paris, D.2
Town, T.3
Rojiani, A.M.4
Sparks, D.L.5
Delledonne, A.6
Crawford, F.7
Abdullah, L.I.8
Humphrey, J.A.9
Dickson, D.W.10
Mullan, M.J.11
-
7
-
-
0035897938
-
Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
-
Kivipelto M, Helkala EL, Laakso MP, Hanninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissi-nen A (2001) Midlife vascular risk factors and Alzheimer's diseaseinlater life: longitudinal, population based study.BMJ 322, 1447-1451. (Pubitemid 32575406)
-
(2001)
British Medical Journal
, vol.322
, Issue.7300
, pp. 1447-1451
-
-
Kivipelto, M.1
Helkala, E.-L.2
Laakso, M.P.3
Hanninen, T.4
Hallikainen, M.5
Alhainen, K.6
Soininen, H.7
Tuomilehto, J.8
Nissien, A.9
-
8
-
-
20844440894
-
Atorvastatin for the treatment of mild to moderate Alzheimer disease: Preliminary results
-
DOI 10.1001/archneur.62.5.753
-
Sparks DL, Sabbagh MN, Connor DJ, Lopez J, Launer LJ, Browne P, Wasser D, Johnson-Traver S, Lochhead J, Ziolwolski C (2005) Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.Arch Neurol 62, 753-757. (Pubitemid 40656090)
-
(2005)
Archives of Neurology
, vol.62
, Issue.5
, pp. 753-757
-
-
Sparks, D.L.1
Sabbagh, M.N.2
Connor, D.J.3
Lopez, J.4
Launer, L.J.5
Browne, P.6
Wasser, D.7
Johnson-Traver, S.8
Lochhead, J.9
Ziolwolski, C.10
-
9
-
-
40649086183
-
The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): Design and baseline characteristics
-
Jones RW, Kivipelto M, Feldman H, Sparks L, Doody R, Waters DD, Hey-Hadavi J, Breazna A, Schindler RJ, Ramos H (2008) The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics. Alzheimers Dement 4, 145-153.
-
(2008)
Alzheimers Dement
, vol.4
, pp. 145-153
-
-
Jones, R.W.1
Kivipelto, M.2
Feldman, H.3
Sparks, L.4
Doody, R.5
Waters, D.D.6
Hey-Hadavi, J.7
Breazna, A.8
Schindler, R.J.9
Ramos, H.10
-
10
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz S, Klein WL (1996) Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271, 4436-4440.
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
11
-
-
0032568843
-
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptidein brainbycholes-terol
-
Howland DS, Trusko SP, Savage MJ, Reaume AG, Lang DM, Hirsch JD, Maeda N, Siman R, Greenberg BD, Scott RW, Flood DG (1998) Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptidein brainbycholes-terol. J Biol Chem 273, 16576-16582.
-
(1998)
J Biol Chem
, vol.273
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maeda, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
12
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
-
DOI 10.1073/pnas.081620098
-
Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P, Runz H, Kuhl S, Bertsch T, von Bergmann K, Hennerici M, Beyreuther K, Hartmann T (2001) Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc Natl Acad Sci USA 98, 5856-5861. (Pubitemid 32435732)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.10
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
Runz, H.7
Kuhl, S.8
Bertsch, T.9
Von Bergmann, K.10
Hennerici, M.11
Beyreuther, K.12
Hartmann, T.13
-
13
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
-
DOI 10.1083/jcb.200207113
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K (2003) Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol 160, 113-123. (Pubitemid 36091721)
-
(2003)
Journal of Cell Biology
, vol.160
, Issue.1
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
14
-
-
0036674082
-
Lipid rafts play an important role in Aβ biogenesis by regulating the β-secretase pathway
-
Tun H, Marlow L, Pinnix I, Kinsey R, Sambamurti K (2002) Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway. J Mol Neurosci 19, 31-35. (Pubitemid 35013331)
-
(2002)
Journal of Molecular Neuroscience
, vol.19
, Issue.1-2
, pp. 31-35
-
-
Tun, H.1
Marlow, L.2
Pinnix, I.3
Kinsey, R.4
Sambamurti, K.5
-
15
-
-
0036180950
-
Cholesterol-dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains
-
DOI 10.1006/nbdi.2001.0470
-
Wahrle S, Das P, Nyborg AC, McLendon C, Shoji M, Kawarabayashi T, Younkin LH, Younkin SG, Golde TE (2002) Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains. Neuro-biol Dis 9, 11-23. (Pubitemid 34174561)
-
(2002)
Neurobiology of Disease
, vol.9
, Issue.1
, pp. 11-23
-
-
Wahrle, S.1
Das, P.2
Nyborg, A.C.3
McLendon, C.4
Shoji, M.5
Kawarabayashi, T.6
Younkin, L.H.7
Younkin, S.G.8
Golde, T.E.9
-
16
-
-
28644451007
-
Regulation of cholesterol and sphin-gomyelin metabolism by amyloid-beta and presenilin
-
Grimm MO, Grimm HS, Patzold AJ, Zinser EG, Halonen R, Duering M, Tschape JA, De Strooper B, Muller U, Shen J, Hartmann T (2005) Regulation of cholesterol and sphin-gomyelin metabolism by amyloid-beta and presenilin. Nat Cell Biol 7, 1118-1123.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 1118-1123
-
-
Grimm, M.O.1
Grimm, H.S.2
Patzold, A.J.3
Zinser, E.G.4
Halonen, R.5
Duering, M.6
Tschape, J.A.7
De Strooper, B.8
Muller, U.9
Shen, J.10
Hartmann, T.11
-
17
-
-
0029942903
-
Origin of cholesterol in myelin
-
DOI 10.1007/BF02527711
-
Morell P, Jurevics H (1996) Origin of cholesterol in myelin. Neurochem Res 21, 463-470. (Pubitemid 26159264)
-
(1996)
Neurochemical Research
, vol.21
, Issue.4
, pp. 463-470
-
-
Morell, P.1
Jurevics, H.2
-
18
-
-
0027298061
-
Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats
-
DOI 10.1016/0306-4522(93)90456-P
-
Poirier J, Baccichet A, Dea D, Gauthier S (1993) Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats. Neuroscience 55, 81-90. (Pubitemid 23194987)
-
(1993)
Neuroscience
, vol.55
, Issue.1
, pp. 81-90
-
-
Poirier, J.1
Baccichet, A.2
Dea, D.3
Gauthier, S.4
-
19
-
-
61949092326
-
Sterols in the central nervous system
-
Mulder M (2009) Sterols in the central nervous system. Curr Opin Clin Nutr Metab Care 12, 152-158.
-
(2009)
Curr Opin Clin Nutr Metab Care
, vol.12
, pp. 152-158
-
-
Mulder, M.1
-
20
-
-
2442557294
-
Brain Cholesterol: Long Secret Life behind a Barrier
-
DOI 10.1161/01.ATV.0000120374.59826.1b
-
Bjorkhem I, Meaney S (2004) Brain cholesterol: long secret life behind a barrier. Arterioscler Thromb Vasc Biol 24, 806-815. (Pubitemid 38620856)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.5
, pp. 806-815
-
-
Bjorkhem, I.1
Meaney, S.2
Fogelman, A.M.3
-
21
-
-
27744510142
-
Role of peroxisome proliferator-activated receptor γ in amyloid precursor protein processing and amyloid β-mediated cell death
-
DOI 10.1042/BJ20050560
-
d'Abramo C, Massone S, Zingg JM, Pizzuti A, Marambaud P, Dalla Piccola B, Azzi A, Marinari UM, Pronzato MA, Ricciarelli R (2005) Roleofperoxisome proliferator-activated receptor gamma in amyloid precursor protein processing and amyloid beta-mediated cell death. Biochem J 391, 693-698. (Pubitemid 41634796)
-
(2005)
Biochemical Journal
, vol.391
, Issue.3
, pp. 693-698
-
-
D'Abramo, C.1
Massone, S.2
Zingg, J.-M.3
Pizzuti, A.4
Marambaud, P.5
Dalla Piccola, B.6
Azzi, A.7
Marinari, U.M.8
Pronzato, M.A.9
Ricciarelli, R.10
-
22
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
DOI 10.1016/S0896-6273(00)80974-5
-
Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939-945. (Pubitemid 27471397)
-
(1997)
Neuron
, vol.19
, Issue.4
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
23
-
-
33746396694
-
Troglitazone, a peroxisome proliferator-activated receptor-γ agonist, decreases tau phosphorylation in CHOtau4R cells
-
DOI 10.1111/j.1471-4159.2006.03931.x
-
d'Abramo C, Ricciarelli R, Pronzato MA, Davies P (2006) Troglitazone, a peroxisome proliferator-activated receptor-gamma agonist, decreases tau phosphorylation in CHOtau4 R cells. J Neurochem 98, 1068-1077. (Pubitemid 44127783)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.4
, pp. 1068-1077
-
-
D'Abramo, C.1
Ricciarelli, R.2
Pronzato, M.A.3
Davies, P.4
-
24
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37, 911-917.
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
25
-
-
41249093188
-
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
-
McDonald JG, Thompson BM, McCrum EC, Russell DW (2007) Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry. Methods Enzymol 432, 145-170.
-
(2007)
Methods Enzymol
, vol.432
, pp. 145-170
-
-
McDonald, J.G.1
Thompson, B.M.2
McCrum, E.C.3
Russell, D.W.4
-
26
-
-
0018379640
-
Determination of free, total, and esterified cholesterol by high-performance liquid chromatography
-
Duncan IW, Culbreth PH, Burtis CA (1979) Determination of free, total, and esterified cholesterol by high-performance liquid chromatography. J Chromatogr 162, 281-292. (Pubitemid 9151458)
-
(1979)
Journal of Chromatography
, vol.162
, Issue.3
, pp. 281-292
-
-
Duncan, I.W.1
Culbreth, P.H.2
Burtis, C.A.3
-
27
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
-
DOI 10.1073/pnas.95.11.6460
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K (1998) Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc Natl Acad Sci USA 95, 6460-6464. (Pubitemid 28249035)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
28
-
-
39249084075
-
Cholesterol retention in Alzheimer's brain is responsible for high beta-and gamma-secretase activities and Abeta production
-
Xiong H, Callaghan D, Jones A, Walker DG, Lue LF, Beach TG, Sue LI, Woulfe J, Xu H, Stanimirovic DB, Zhang W (2008) Cholesterol retention in Alzheimer's brain is responsible for high beta-and gamma-secretase activities and Abeta production. Neurobiol Dis 29, 422-437.
-
(2008)
Neurobiol Dis
, vol.29
, pp. 422-437
-
-
Xiong, H.1
Callaghan, D.2
Jones, A.3
Walker, D.G.4
Lue, L.F.5
Beach, T.G.6
Sue, L.I.7
Woulfe, J.8
Xu, H.9
Stanimirovic, D.B.10
Zhang, W.11
-
29
-
-
0035834416
-
CNS synaptogenesis promoted by glia-derived cholesterol
-
DOI 10.1126/science.294.5545.1354
-
Mauch DH, Nagler K, Schumacher S, Goritz C, Muller EC, Otto A, Pfrieger FW (2001) CNS synaptogenesis promoted by glia-derived cholesterol. Science 294, 1354-1357. (Pubitemid 33063104)
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1354-1357
-
-
Mauch, D.H.1
Nagier, K.2
Schumacher, S.3
Goritz, C.4
Muller, E.-C.5
Otto, A.6
Pfrieger, F.W.7
-
30
-
-
12244255799
-
ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease
-
DOI 10.1016/S0197-4580(02)00094-5, PII S0197458002000945
-
Wollmer MA, Streffer JR, Lutjohann D, Tsolaki M, Iakovidou V, Hegi T, Pasch T, Jung HH, Bergmann K, Nitsch RM, Hock C, Papassotiropoulos A (2003) ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease. Neurobiol Aging 24, 421-426. (Pubitemid 36205049)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.3
, pp. 421-426
-
-
Wollmer, M.A.1
Streffer, J.R.2
Lutjohann, D.3
Tsolaki, M.4
Iakovidou, V.5
Hegi, T.6
Pasch, T.7
Jung, H.H.8
Von Bergmann, K.9
Nitsch, R.M.10
Hock, C.11
Papassotiropoulos, A.12
-
31
-
-
4644295495
-
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain
-
DOI 10.1074/jbc.M407962200
-
Hirsch-Reinshagen V, Zhou S, Burgess BL, Bernier L, McIsaac SA, Chan JY, Tansley GH, Cohn JS, Hayden MR, Wellington CL (2004) Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain. J Biol Chem 279, 41197-41207. (Pubitemid 39287722)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.39
, pp. 41197-41207
-
-
Hirsch-Reinshagen, V.1
Zhou, S.2
Burgess, B.L.3
Bernier, L.4
McIsaac, S.A.5
Chan, J.Y.6
Tansley, G.H.7
Cohn, J.S.8
Hayden, M.R.9
Wellington, C.L.10
-
32
-
-
4644361588
-
ABCA1 is required for normal central nervous system apoE levels and for lipidation of astrocyte-secreted apoE
-
DOI 10.1074/jbc.M407963200
-
Wahrle SE, Jiang H, Parsadanian M, Legleiter J, Han X, Fryer JD, Kowalewski T, Holtzman DM (2004) ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE. J Biol Chem 279, 40987-40993. (Pubitemid 39287699)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.39
, pp. 40987-40993
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Legleiter, J.4
Han, X.5
Fryer, J.D.6
Kowalewski, T.7
Holtzman, D.M.8
-
33
-
-
0037710127
-
Cholesterol homeostasis and function in neurons of the central nervous system
-
Pfrieger FW (2003) Cholesterol homeostasis and function in neurons of the central nervous system. Cell Mol Life Sci 60, 1158-1171. (Pubitemid 36791918)
-
(2003)
Cellular and Molecular Life Sciences
, vol.60
, Issue.6
, pp. 1158-1171
-
-
Pfrieger, F.W.1
-
34
-
-
0037230328
-
Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?
-
DOI 10.1002/bies.10195
-
Pfrieger FW (2003) Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? Bioessays 25, 72-78. (Pubitemid 36093328)
-
(2003)
BioEssays
, vol.25
, Issue.1
, pp. 72-78
-
-
Pfrieger, F.W.1
-
35
-
-
0032813660
-
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
-
DOI 10.1038/11921
-
Rust S, Rosier M, Funke H, Real J, Amoura Z, Piette JC, Deleuze JF, Brewer HB, Duverger N, Denefle P, Assmann G (1999) Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet 22, 352-355. (Pubitemid 29369525)
-
(1999)
Nature Genetics
, vol.22
, Issue.4
, pp. 352-355
-
-
Rust, S.1
Rosier, M.2
Funke, H.3
Real, J.4
Amoura, Z.5
Piette, J.-C.6
Deleuze, J.-F.7
Brewer, H.B.8
Duverger, N.9
Denefle, P.10
Assmann, G.11
-
36
-
-
30044441879
-
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease
-
DOI 10.1074/jbc.M508781200
-
Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL (2005) The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine modelsof Alzheimer disease.J Biol Chem 280, 43243-43256. (Pubitemid 43049291)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.52
, pp. 43243-43256
-
-
Hirsch-Reinshagen, V.1
Maia, L.F.2
Burgess, B.L.3
Blain, J.-F.4
Naus, K.E.5
McIsaac, S.A.6
Parkinson, P.F.7
Chan, J.Y.8
Tansley, G.H.9
Hayden, M.R.10
Poirier, J.11
Van Nostrand, W.12
Wellington, C.L.13
-
37
-
-
30044438463
-
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
-
DOI 10.1074/jbc.M504513200
-
Koldamova R, Staufenbiel M, Lefterov I (2005) Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. J Biol Chem 280, 43224-43235. (Pubitemid 43049289)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.52
, pp. 43224-43235
-
-
Koldamova, R.1
Staufenbiel, M.2
Lefterov, I.3
-
38
-
-
30044442937
-
Deletion of Abca1 increases Aβ deposition in the PDAPP transgenic mouse model of Alzheimer disease
-
DOI 10.1074/jbc.M508780200
-
Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM (2005) Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. J Biol Chem 280, 43236-43242. (Pubitemid 43049290)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.52
, pp. 43236-43242
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Hartman, R.E.4
Bales, K.R.5
Paul, S.M.6
Holtzman, D.M.7
-
39
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD (1993) Apolipopro-tein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 90, 1977-1981. (Pubitemid 23069980)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.5
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
40
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
Sparks DL, Scheff SW, Hunsaker JC 3 rd, Liu H, Landers T, Gross DR (1994) Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol 126, 88-94.
-
(1994)
Exp Neurol
, vol.126
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker III, J.C.3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
41
-
-
0037171095
-
Diet-induced hypercholesterolemia enhances brain Aβ accumulation in transgenic mice
-
Shie FS, Jin LW, Cook DG, Leverenz JB, LeBoeuf RC (2002) Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice. Neuroreport 13, 455-459. (Pubitemid 34293189)
-
(2002)
NeuroReport
, vol.13
, Issue.4
, pp. 455-459
-
-
Shie, F.-S.1
Jin, L.-W.2
Cook, D.G.3
Leverenz, J.B.4
LeBoeuf, R.C.5
-
42
-
-
67651176274
-
Brain sterol dysregulation in sporadic AD and MCI: Relationship to heme oxygenase-1
-
Hascalovici JR, Vaya J, Khatib S, Holcroft CA, Zukor H, Song W, Arvanitakis Z, Bennett DA, Schipper HM (2009) Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1. J Neurochem 110, 1241-1253.
-
(2009)
J Neurochem
, vol.110
, pp. 1241-1253
-
-
Hascalovici, J.R.1
Vaya, J.2
Khatib, S.3
Holcroft, C.A.4
Zukor, H.5
Song, W.6
Arvanitakis, Z.7
Bennett, D.A.8
Schipper, H.M.9
-
43
-
-
0025148205
-
Rates of cholesterol, ubiquinone, dolichol and dolichyl-P biosynthesis in rat brain slices
-
DOI 10.1016/0014-5793(90)81107-Y
-
Andersson M, Elmberger PG, Edlund C, Kristensson K, Dall-ner G (1990) Rates of cholesterol, ubiquinone, dolichol and dolichyl-P biosynthesis in rat brain slices. FEBS Lett 269, 15-18. (Pubitemid 20245305)
-
(1990)
FEBS Letters
, vol.269
, Issue.1
, pp. 15-18
-
-
Andersson, M.1
Elmberger, P.G.2
Edlund, C.3
Kristensson, K.4
Dallner, G.5
-
44
-
-
0031848338
-
Cholesterol homeostasis in human brain: Turnover of 24S- hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
-
Bjorkhem I, Lutjohann D, Diczfalusy U, Stahle L, Ahlborg G, Wahren J (1998) Cholesterol homeostasis in human brain: turnover of 24S- hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. J Lipid Res 39, 1594-1600. (Pubitemid 28377923)
-
(1998)
Journal of Lipid Research
, vol.39
, Issue.8
, pp. 1594-1600
-
-
Bjorkhem, I.1
Lutjohann, D.2
Diczfalusy, U.3
Stahle, L.4
Ahlborg, G.5
Wahren, J.6
-
45
-
-
0343775806
-
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients
-
Lutjohann D, Papassotiropoulos A, Bjorkhem I, Locatelli S, Bagli M, Oehring RD, Schlegel U, Jessen F, Rao ML, von Bergmann K, Heun R (2000) Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res 41, 195-198. (Pubitemid 30117859)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.2
, pp. 195-198
-
-
Lutjohann, D.1
Papassotiropoulos, A.2
Bjorkhem, I.3
Locatelli, S.4
Bagli, M.5
Oehring, R.D.6
Schlegel, U.7
Jessen, F.8
Rao, M.L.9
Von Bergmann, K.10
Heun, R.11
-
46
-
-
0037052771
-
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls
-
DOI 10.1016/S0304-3940(02)00164-7, PII S0304394002001647
-
Schonknecht P, Lutjohann D, Pantel J, Bardenheuer H, Hart-mann T, von Bergmann K, Beyreuther K, Schroder J (2002) Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls. Neurosci Lett 324, 83-85. (Pubitemid 34442684)
-
(2002)
Neuroscience Letters
, vol.324
, Issue.1
, pp. 83-85
-
-
Schonknecht, P.1
Lutjohann, D.2
Pantel, J.3
Bardenheuer, H.4
Hartmann, T.5
Von Bergmann, K.6
Beyreuther, K.7
Schroder, J.8
-
47
-
-
76449103011
-
Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus
-
Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V (2010) Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus. Brain Res 1318, 167-177.
-
(2010)
Brain Res
, vol.1318
, pp. 167-177
-
-
Akram, A.1
Schmeidler, J.2
Katsel, P.3
Hof, P.R.4
Haroutunian, V.5
-
48
-
-
77953285846
-
Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons
-
Kim WS, Bhatia S, Elliott DA, Agholme L, Kagedal K, McCann H, Halliday GM, Barnham KJ, Garner B (2010) Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons. J Alzheimers Dis 21, 193-205.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 193-205
-
-
Kim, W.S.1
Bhatia, S.2
Elliott, D.A.3
Agholme, L.4
Kagedal, K.5
McCann, H.6
Halliday, G.M.7
Barnham, K.J.8
Garner, B.9
-
49
-
-
79958857741
-
The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Abeta fragment generation
-
Davis W Jr (2010) The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Abeta fragment generation. Curr Alzheimer Res 7, 566-577.
-
(2010)
Curr Alzheimer Res
, vol.7
, pp. 566-577
-
-
Davis Jr., W.1
|