Post-translational modifications of the cardiac Na channel: Contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 4, 2013, Pages

  Herren, Anthony W ^a   Bers, Donald M ^a   Grandi, Eleonora ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Arrhythmia; CaMKII; Heart failure; Na channel; Phosphorylation

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CAVEOLIN 3; GLUTATHIONE TRANSFERASE; GLYCEROL 2 ACETATE 1 OLEATE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SODIUM CHANNEL NAV1.5;

ALPHA CHAIN; BRUGADA SYNDROME; CHANNEL GATING; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART CONDUCTION; HEART FAILURE; HEART INFARCTION; HEART MUSCLE CONDUCTION DISTURBANCE; HEART MUSCLE EXCITABILITY; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REFRACTORY PERIOD; HEART REPOLARIZATION; HEART VENTRICLE HYPERTROPHY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LONG QT SYNDROME; LOSS OF FUNCTION MUTATION; MACROMOLECULE; MITOCHONDRION; NITROSYLATION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; QT INTERVAL; REVIEW; SODIUM CHANNELOPATHY; ST SEGMENT ELEVATION;

ARRHYTHMIA; CAMKII; HEART FAILURE; NA CHANNEL; PHOSPHORYLATION;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ION CHANNEL GATING; KINETICS; MUTATION; MYOCARDIUM; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PHENOTYPE; PHOSPHORYLATION; PROGNOSIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SODIUM;

EID: 84881639229     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00306.2013     Document Type: Review

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