A double tyrosine motif in the cardiac sodium channel domain III-IV linker couples calcium-dependent calmodulin binding to inactivation gating

Journal of Biological Chemistry

Volumn 284, Issue 48, 2009, Pages 33265-33274

  Sarhan, Maen F ^a   Van Petegem, Filip ^a   Ahern, Christopher A ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b NONE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC RESIDUES; CALCIUM BINDING PROTEINS; CALCIUM REGULATION; CALMODULIN BINDING; CAM-BINDING SITE; CYTOSOLIC; CYTOSOLIC CALCIUM; FUNCTIONAL RELEVANCE; INACTIVATION GATING; INTRACELLULAR CALCIUM; ISOTHERMAL TITRATION CALORIMETRY; LINKER PEPTIDE; MOLECULAR BASIS; MUSCLE CELL; N-TERMINALS; SIDE CHAINS; SODIUM CHANNEL; TRANSMEMBRANES;

AMINES; AMINO ACIDS; BINDING ENERGY; CALCIUM; CALCIUM ALLOYS; CAMS; TOXIC MATERIALS;

BINDING SITES;

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM ION; TYROSINE; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALORIMETRY; CONTROLLED STUDY; CYTOSOL; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION;

AMINO ACID MOTIFS; BINDING SITES; CALCIUM; CALCIUM CHLORIDE; CALMODULIN; CELL LINE; HUMANS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MUSCLE PROTEINS; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SODIUM CHANNELS; THERMODYNAMICS; TRANSFECTION; TYROSINE;

EID: 70450285134     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.052910     Document Type: Article

References (37)

1. Horn, R., Patlak, J., and Stevens, C. F. (1981) Nature 291, 426-427
2. Joseph, D., Petsko, G. A., and Karplus, M. (1990) Science 249, 1425-1428
3. West, J. W., Patton, D. E., Scheuer, T., Wang, Y., Goldin, A. L., and Catterall, W. A. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 10910-10914
4. Smith, M. R., and Goldin, A. L. (1997) Biophys. J. 73, 1885-1895
5. McPhee, J. C., Ragsdale, D. S., Scheuer, T., and Catterall, W. A. (1998) J. Biol. Chem. 273, 1121-1129
6. Tan, H. L., Kupershmidt, S., Zhang, R., Stepanovic, S., Roden, D. M., Wilde, A. A., Anderson, M. E., and Balser, J. R. (2002) Nature 415, 442-447
7. Kass, R. S. (2006) J. Cardiovasc. Electrophysiol. 17, Suppl. 1, S21-S25
8. Grieco, T. M., Malhotra, J. D., Chen, C., Isom, L. L., and Raman, I. M. (2005) Neuron 45, 233-244
9. West, J. W., Numann, R., Murphy, B. J., Scheuer, T., and Catterall, W. A. (1991) Science 254, 866-868
10. Ahern, C. A., Zhang, J. F., Wookalis, M. J., and Horn, R. (2005) Circ. Res. 96, 991-998
11. Young, K. A., and Caldwell, J. H. (2005) J. Physiol. 565, 349-370
12. Deschênes, I., Neyroud, N., DiSilvestre, D., Marbán, E., Yue, D. T., and Tomaselli, G. F. (2002) Circ. Res. 90, E49-E57
13. Wingo, T. L., Shah, V. N., Anderson, M. E., Lybrand, T. P., Chazin, W. J., and Balser, J. R. (2004) Nat. Struct. Mol. Biol. 11, 219-225
14. Kim, J., Ghosh, S., Liu, H., Tateyama, M., Kass, R. S., and Pitt, G. S. (2004) J. Biol. Chem. 279, 45004-45012
15. Mori, M., Konno, T., Ozawa, T., Murata, M., Imoto, K., and Nagayama, K. (2000) Biochemistry 39, 1316-1323
16. Biswas, S., DiSilvestre, D., Tian, Y., Halperin, V. L., and Tomaselli, G. F. (2009) Circ. Res. 104, 870-878
17. Motoike, H. K., Liu, H., Glaaser, I. W., Yang, A. S., Tateyama, M., and Kass, R. S. (2004) J. Gen. Physiol. 123, 155-165
18. Potet, F., Chagot, B., Anghelescu, M., Viswanathan, P. C., Stepanovic, S. Z., Kupershmidt, S., Chazin, W. J., and Balser, J. R. (2009) J. Biol. Chem. 284, 8846-8854
19. George, A. L., Jr. (2005) J. Clin. Invest. 115, 1990-1999
20. Viswanathan, P. C., and Balser, J. R. (2004) Trends Cardiovasc. Med. 14, 28-35
21. Wagner, S., Dybkova, N., Rasenack, E. C., Jacobshagen, C., Fabritz, L., Kirchhof, P., Maier, S. K., Zhang, T., Hasenfuss, G., Brown, J. H., Bers, D. M., and Maier, L. S. (2006) J. Clin. Invest. 116, 3127-3138
22. Maltsev, V. A., Reznikov, V., Undrovinas, N. A., Sabbah, H. N., and Undrovinas, A. (2008) Am. J. Physiol. Heart Circ. Physiol. 294, H1597-H1608
23. Van Petegem, F., Chatelain, F. C., and Minor, D. L., Jr. (2005) Nat. Struct. Mol. Biol. 12, 1108-1115
24. Edelhoch, H. (1967) Biochemistry 6, 1948-1954
25. Gellens, M. E., George, A. L., Jr., Chen, L. Q., Chahine, M., Horn, R., Barchi, R. L., and Kallen, R. G. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 554-558
26. Long, S. B., Campbell, E. B., and Mackinnon, R. (2005) Science 309, 897-903
27. Rohl, C. A., Boeckman, F. A., Baker, C., Scheuer, T., Catterall, W. A., and Klevit, R. E. (1999) Biochemistry 38, 855-861
28. O'Leary, M. E., Chen, L. Q., Kallen, R. G., and Horn, R. (1995) J. Gen. Physiol. 106, 641-658
29. Dunitz, J. D. (1995) Chem. Biol. 2, 709-712
30. Bankston, J. R., Yue, M., Chung, W., Spyres, M., Pass, R. H., Silver, E., Sampson, K. J., and Kass, R. S. (2007) PLoS One 2, e1258
31. Yap, K. L., Kim, J., Truong, K., Sherman, M., Yuan, T., and Ikura, M. (2000) J. Struct. Funct. Genomics 1, 8-14
32. Melillo, G., Lima, J. A., Judd, R. M., Goldschmidt-Clermont, P. J., and Silverman, H. S. (1996) Circulation 93, 1447-1458
33. Chaudhuri, D., Issa, J. B., and Yue, D. T. (2007) J. Gen. Physiol. 129, 385-401
34. Fallon, J. L., Halling, D. B., Hamilton, S. L., and Quiocho, F. A. (2005) Structure 13, 1881-1886
35. Kim, E. Y., Rumpf, C. H., Fujiwara, Y., Cooley, E. S., Van Petegem, F., and Minor, D. L., Jr. (2008) Structure 16, 1455-1467
36. Fallon, J. L., Baker, M. R., Xiong, L., Loy, R. E., Yang, G., Dirksen, R. T., Hamilton, S. L., and Quiocho, F. A. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 5135-5140
37. Dick, I. E., Tadross, M. R., Liang, H., Tay, L. H., Yang, W., and Yue, D. T. (2008) Nature 451, 830-834