Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43

Journal of Molecular Medicine

Volumn 89, Issue 7, 2011, Pages 677-687

  Iravanian, Shahriar ^a   Sovari, Ali A ^b   Lardin, Harvey A ^b   Liu, Hong ^b   Xiao, Hong D ^c   Dolmatova, Elena ^d   Jiao, Zhe ^a   Harris, Brett S ^e   Witham, Emily A ^f   Gourdie, Robert G ^e   Duffy, Heather S ^d   Bernstein, Kenneth E ^g   Dudley Jr , Samuel C ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

ACE; Angiotensin; Arrhythmia; Connexin; Electrophysiology

Indexed keywords

CAPTOPRIL; CONNEXIN 43; DIPEPTIDYL CARBOXYPEPTIDASE; FLUORESCENT DYE; LOSARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CELL MEMBRANE CONDUCTANCE; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROPHYSIOLOGY; FEMALE; GAP JUNCTION; GENE OVEREXPRESSION; HEART VENTRICLE TACHYCARDIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PATCH CLAMP; PROTEIN PHOSPHORYLATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM CURRENT; SUDDEN DEATH; SURVIVAL; WHOLE CELL;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CONNEXIN 43; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCYTES, CARDIAC; PEPTIDYL-DIPEPTIDASE A; PHOSPHORYLATION; RENIN-ANGIOTENSIN SYSTEM; RISK; TACHYCARDIA, VENTRICULAR;

EID: 79960011785     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0761-3     Document Type: Article

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