Selective γ-ketoaldehyde scavengers protect NaV1.5 from oxidant-induced inactivation

Journal of Molecular and Cellular Cardiology

Volumn 48, Issue 2, 2010, Pages 352-359

  Nakajima, T ^a   Davies, S S ^a   Matafonova, E ^a   Potet, F ^a   Amarnath, V ^a   Tallman, K A ^a   Serwa, R A ^a   Porter, N A ^a   Balser, J R ^a   Kupershmidt, S ^a   Roberts III, L J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Arrhythmia; Ion channels; Oxidative stress; Reactive carbonyls

Indexed keywords

ALDEHYDE DERIVATIVE; ARACHIDONIC ACID; GAMMA KETOALDEHYDE; LYSINE; REACTIVE OXYGEN METABOLITE; SCAVENGER; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANTIARRHYTHMIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; HEART CELL CULTURE; HEART INFARCTION; HUMAN; HUMAN CELL; HYPERPOLARIZATION; LIPID PEROXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; SODIUM CURRENT;

ACTION POTENTIALS; ALDEHYDES; AMINES; CELL LINE; FREE RADICAL SCAVENGERS; HUMANS; ION CHANNEL GATING; KINETICS; OXIDANTS; OXIDATIVE STRESS; SODIUM CHANNELS; TERT-BUTYLHYDROPEROXIDE;

EID: 74149088419     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.11.016     Document Type: Article

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