Ca2+/calmodulin-dependent protein kinase ii-based regulation of voltage-gated na+ channel in cardiac disease

Circulation

Volumn 126, Issue 17, 2012, Pages 2084-2094

  Koval, Olha M ^a   Snyder, Jedidiah S ^a,b   Wolf, Roseanne M ^a,h   Pavlovicz, Ryan E ^a,c   Glynn, Patric ^a,c   Curran, Jerry ^a   Leymaster, Nicholas D ^f   Dun, Wen ^g   Wright, Patrick J ^a   Cardona, Natalia ^d   Qian, Lan ^e   Mitchell, Colleen C ^h   Boyden, Penelope A ^g   Binkley, Philip F ^d   Li, Chenglong ^c   Anderson, Mark E ^f,g   Mohler, Peter J ^d,e   Hund, Thomas J ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b Department of Biomedical Engineering   (United States)

^c Division of Medicinal Chemistry and Pharmocognosy   (United States)

^d Department of Internal Medicine ^*  (United States)

^e THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^f UNIVERSITY OF IOWA   (United States)

^g UNIVERSITY OF IOWA   (United States)

^h Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

arrhythmias, cardiac; calcium calmodulin dependent protein kinase II; heart failure; ion channels; long QT syndrome; myocardial infarction

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; SODIUM CHANNEL NAV1.5;

ANIMAL CELL; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART DISEASE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROCESSING;

ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELLS, CULTURED; CYTOPLASM; DOGS; GENETIC VARIATION; HEK293 CELLS; HUMANS; MICE; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84867777430     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.105320     Document Type: Article

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