Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes: Implications for the arrhythmogenesis of human siderotic heart disease

Circulation

Volumn 100, Issue 6, 1999, Pages 675-683

  Kuryshev, Yuri A ^a,b   Brittenham, Gary M ^a,f   Fujioka, Hisashi ^a   Kannan, Perry ^a   Shieh, Char Chang ^a,e   Cohen, Sidney A ^c   Brown, Arthur M ^a,b,d  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CENTOCOR INC   (United States)

^d Rammelkamp Center   (United States)

^e ABBOTT LABORATORIES   (United States)

^f NONE   (United States)

Author keywords

Cardiomyopathy; Gerbil; Iron overload; Potassium channels; Sodium channels

Indexed keywords

CELL MEMBRANE PROTEIN; IRON; POTASSIUM ION; SODIUM CHANNEL; SODIUM ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; GERBIL; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE EXCITABILITY; HEART MUSCLE POTENTIAL; HEART VENTRICLE ARRHYTHMIA; IRON OVERLOAD; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIDEROSIS; SODIUM CURRENT; TISSUE LEVEL;

EID: 0033543124     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.100.6.675     Document Type: Article

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