Post-transcriptional silencing of SCN1B AND SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 4, 2011, Pages

  Mishra, Sudhish ^a   Undrovinas, Nidas A ^a   Maltsev, Victor A ^b   Reznikov, Vitaliy ^a   Sabbah, Hani N ^a   Undrovinas, Albertas ^a  

^a HENRY FORD HOSPITAL   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Action potential; In silico simulation

Indexed keywords

ADENOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN; SMALL INTERFERING RNA; SODIUM CHANNEL; SODIUM CHANNEL NAV BETA1; SODIUM CHANNEL NAV BETA2; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL EMBOLISM; CELL CULTURE; CELL ISOLATION; COMPUTER MODEL; CONTROLLED STUDY; CORONARY ARTERY; EXCITATION CONTRACTION COUPLING; EXPERIMENTAL DOG; GENETIC TRANSFECTION; HEART FAILURE; HEART MUSCLE CELL; MODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIMULATION; SODIUM CURRENT; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; WHOLE CELL;

ACTION POTENTIALS; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHRONIC DISEASE; DOGS; HEART FAILURE; MEMBRANE PROTEINS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SODIUM CHANNELS; TRANSFECTION;

EID: 80053268782     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00948.2009     Document Type: Article

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