Downregulation of neuronal sodium channel subunits Nav1.1 and Nav1.6 in the sinoatrial node from volume-overloaded heart failure rat

Pflugers Archiv European Journal of Physiology

Volumn 454, Issue 3, 2007, Pages 451-459

  Du, Yuan ^a   Huang, Xin ^a   Wang, Tingzhong ^a   Han, Ke ^a   Zhang, Junbo ^a   Xi, Yutao ^a   Wu, Geru ^a   Ma, Aiqun ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Heart failure; Laser capture microdissection; Pacemaker current; Sinoatrial node; Sodium channel

Indexed keywords

MESSENGER RNA; PROTEIN SUBUNIT; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOVENOUS SHUNT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HEART FAILURE; HEART HEMODYNAMICS; HEART NERVE; HEART RHYTHM; HEART VENTRICLE OVERLOAD; HEART VOLUME; IMMUNOHISTOCHEMISTRY; MALE; MEDICAL INFORMATION; MOLECULAR DYNAMICS; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINUS ARRHYTHMIA; SINUS NODE; SINUS NODE RECOVERY TIME; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DOWN-REGULATION; HEART FAILURE, CONGESTIVE; HEART RATE; MALE; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SINOATRIAL NODE; SODIUM CHANNELS;

EID: 34248354261     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0216-4     Document Type: Article

References (32)

1. Jose AD, Collison D (1970) The normal range and determinants of the intrinsic heart rate in man. Cardiovasc Res 4:160-167
2. Satoh H (2003) Sino-atrial nodal cells of mammalian hearts: ionic currents and gene expression of pacemaker ionic channels. J Smooth Muscle Res 39:175-193
3. Verkerk AO, Wilders R, Coronel R, Ravesloot JH, Verheijck EE (2003) Ionic remodeling of sinoatrial node cells by heart failure. Circulation 108:760-766
4. Zicha S, Fernandez-Velasco M, Lonardo G, L'Heureux N, Nattel S (2005) Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model. Cardiovasc Res 66:472-481
5. Goldin AL (2001) Resurgence of sodium channel research. Annu Rev Physiol 63:871-894
6. Benson DW, Wang DW, Dyment M, Knilans TK, Fish FA, Strieper MJ, Rhodes TH, George AL Jr (2003) Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A). J Clin Invest 112:1019-1028
7. Maier SK, Westenbroek RE, Yamanushi TT, Dobrzynski H, Boyett MR, Catterall WA, Scheuer T (2003) An unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node. Proc Natl Acad Sci USA 100:3507-3512
8. Lei M, Jones SA, Liu J, Lancaster MK, Fung SS, Dobrzynski H, Camelliti P, Maier SK, Noble D, Boyett MR (2004) Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking. J Physiol 559:835-848
9. Flaim SF, Minteer WJ, Zelis R (1980) Acute effects of arteriovenous shunt on cardiovascular hemodynamics in rat. Pflugers Arch 385:203-209
10. Grimm D, Holmer SR, Riegger GA, Kromer EP (1999) Effects of beta-receptor blockade and angiotensin II type I receptor antagonism in isoproterenol-induced heart failure in the rat. Cardiovasc Pathol 8:315-323
11. Mulder P, Barbier S, Chagraoui A, Richard V, Henry JP, Lallemand F, Renet S, Lerebours G, Mahlberg-Gaudin F, Thuillez C (2004) Long-term heart rate reduction induced by the selective I (f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure. Circulation 109:1674-1679
12. Dent MR, Singal T, Dhalla NS, Tappia PS (2004) Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due tomyocardial infarction. J Cell Mol Med 8:526-536
13. Elvan A, Wylie K, Zipes DP (1996) Pacing-induced chronic atrial fibrillation impairs sinus node function in dogs. Electrophysiological remodeling. Circulation 94:2953-2960
14. Dobrzynski H, Rothery SM, Marples DD, Coppen SR, Takagishi Y, Honjo H, Tamkun MM, Henderson Z, Kodama I, Severs NJ, Boyett MR (2000) Presence of the Kv1.5 K(+) channel in the sinoatrial node. J Histochem Cytochem 48:769-780
15. Musa H, Dobrzynski H, Berry Z, Abidi F, Cass CE, Young JD, Baldwin SA, Boyett MR (2002) Immunocytochemical demonstration of the equilibrative nucleoside transporter rENT1 in rat sinoatrial node. J Histochem Cytochem 50:305-309
16. Jacquet R, Hillyer J, Landis WJ (2005) Analysis of connective tissues by laser capture microdissection and reverse transcriptase-polymerase chain reaction. Anal Biochem 337:22-34
17. Antoni H, Bocker D, Eickhorn R (1988) Sodium current kinetics in intact rat papillary muscle: measurements with the loose-patch-clamp technique. J Physiol 406:199-213
18. ten Velde I, de Jonge B, Verheijck EE, van Kempen MJ, Analbers L, Gros D, Jongsma HJ (1995) Spatial distribution of connexin43, the major cardiac gap junction protein, visualizes the cellular network for impulse propagation from sinoatrial node to atrium. Circ Res 76:802-811
19. Boyett MR, Dobrzynski H, Lancaster MK, Jones SA, Honjo H, Kodama I (2003) Sophisticated architecture is required for the sinoatrial node to perform its normal pacemaker function. J Cardiovasc Electrophysiol 14:104-106
20. Kucera JP, Rohr S, Rudy Y (2002) Localization of sodium channels in intercalated disks modulates cardiac conduction. Circ Res 91:1176-1182
21. Lei M, Goddard C, Liu J, Leoni AL, Royer A, Fung SS, Xiao G, Ma A, Zhang H, Charpentier F, Vandenberg JI, Colledge WH, Grace AA, Huang CL (2005) Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a. J Physiol 567:387-400
22. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408
23. Dhar Malhotra J, Chen C, Rivolta I, Abriel H, Malhotra R, Mattei LN, Brosius FC, Kass RS, Isom LL (2001) Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes. Circulation 103:1303-1310
24. Maier SK, Westenbroek RE, Schenkman KA, Feigl EO, Scheuer T, Catterall WA (2002) An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart. Proc Natl Acad Sci USA 99:4073-4078
25. Haufe V, Cordeiro JM, Zimmer T, Wu YS, Schiccitano S, Benndorf K, Dumaine R (2005) Contribution of neuronal sodium channels to the cardiac fast sodium current INa is greater in dog heart Purkinje fibers than in ventricles. Cardiovasc Res 65:117-127
26. Baruscotti M, Westenbroek R, Catterall WA, DiFrancesco D, Robinson RB (1997) The newborn rabbit sino-atrial node expresses a neuronal type I-like Na+ channel. J Physiol 498 (Pt 3):641-648
27. Rush AM, Craner MJ, Kageyama T, Dib-Hajj SD, Waxman SG, Ranscht B (2005) Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons. Eur J Neurosci 22:39-49
28. Opthof T, Coronel R, Rademaker HM, Vermeulen JT, Wilms-Schopman FJ, Janse MJ (2000) Changes in sinus node function in a rabbit model of heart failure with ventricular arrhythmias and sudden death. Circulation 101:2975-2980
29. Sanders P, Kistler PM, Morton JB, Spence SJ, Kalman JM (2004) Remodeling of sinus node function in patients with congestive heart failure: reduction in sinus node reserve. Circulation 110:897-903
30. Tomaselli GF, Marban E (1999) Electrophysiological remodeling in hypertrophy and heart failure. Cardiovasc Res 42:270-283
31. Li D, Melnyk P, Feng J, Wang Z, Petrecca K, Shrier A, Nattel S (2000) Effects of experimental heart failure on atrial cellular and ionic electrophysiology. Circulation 101:2631-2638
32. Han W, Chartier D, Li D, Nattel S (2001) Ionic remodeling of cardiac Purkinje cells by congestive heart failure. Circulation 104:2095-2100