Abnormal cardiac Na+ channel properties and QT heart rate adaptation in neonatal ankyrin(B) knockout mice

Circulation Research

Volumn 86, Issue 4, 2000, Pages 441-447

  Chauhan, Vijay S ^a   Tuvia, Shmuel ^b   Buhusi, Mona ^b   Bennett, Vann ^b   Grant, Augustus O ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cytoskeleton; Long QT syndrome; Na+ channel; Repolarization; Transgenic mice

Indexed keywords

ANKYRIN; SODIUM CHANNEL;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHANNEL GATING; CYTOSKELETON; ELECTROCARDIOGRAM; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART RATE; HEART REPOLARIZATION; LONG QT SYNDROME; MOUSE; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; VOLTAGE CLAMP;

EID: 0034599086     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.4.441     Document Type: Article

References (25)

1. Bennett V, Gilligan DM. The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane. Annu Rev Cell Biol. 1993;9:27-66.
2. Pardo JV, Siliciano JD, Craig SW. A vinculin-containing cortical lattice in skeletal muscle: transverse lattice elements ("costameres") mark sites of attachment between myofibrils and sarcolemma. Proc Natl Acad Sci USA. 1983;80:1008-1012.
3. ++ homeostasis proteins. J Cell Biol. 1999;147:995-1008.
4. Undrovinas AI, Shander GS, Makielski JC. Cytoskeleton modulates gating of voltage-dependent sodium channel in heart. Am J Physiol. 1995;269:H203-H214.
5. ++ transient in rat ventricular cardiomyocytes: an effect of altered actin cytoskeleton? J Mol Cell Cardiol. 1998;30:1665-1670.
6. ATP channel opening in patches from guinea-pig cardiomyocytes. J Physiol. 1996;492:395-404.
7. Bennett PB, Yazawa K, Makita N, George AJ. Molecular mechanisms for an inherited cardiac arrhythmias. Nature. 1995;376:683-685.
8. Chandra R, Starmer CF, Grant AO. Multiple effects of KPQ deletion mutation on gating of human cardiac Na channels expressed in mammalian cells. Am J Physiol. 1998;274:H1643-H1654.
9. Scotland P, Zhou D, Benveniste H, Bennett V. Nervous system defects of AnkyrinB(-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD ankyrin-B in premyelinated axons. J Cell Biol. 1998;143:1305-1315.
10. Whalley DW, Wendt DJ, Starmer CF, Rudy Y, Grant AO. Voltage-independent effects of extracellular K on the Na current and phase 0 of the action potential in isolated cardiac myocytes. Circ Res. 1994;75: 491-502.
11. Funck-Brentano C, Jaillon P. Rate-corrected QT interval: techniques and limitations. Am J Cardiol. 1993;72:17B-22B.
12. Yue DT, Lawrence JH, Marbán E. Two molecular transitions influence cardiac sodium channel gating. Science. 1989;244:349-352.
13. Aldrich RW, Corey DP, Stevens CF. A reinterpretation of mammalian sodium channel gating on single channel recording. Nature. 1983;306: 436-441.
14. Lipka LJ, Siegelbaum SA, Robinson RB, Berman MF. An analogue of cAMP mimics developmental changes in neonatal rat ventricular myocyte sodium current kinetics. Am J Physiol. 1996;270:H194-H199.
15. Wang L, Duff HJ. Developmental changes in transient outward current in mouse ventricle. Circ Res. 1997;81:120-127.
16. Pratt AG, Bertorello AM, Ausiello DA, Cantiello HF. Activation of epithelial Na channels by protein kinase A requires actin filaments. Am J Physiol. 1993;265:C224-C233.
17. Negulyaev YA, Vedernikove EA, Maximov AV. Disruption of actin filaments increases the activity of sodium-conducting channels in human myeloid leukemia cells. Mol Biol Cell. 1996;7:1857-1864.
18. Curran ME, Splawski I, Timothy KW, Vincent GM, Green ED, Keating MT. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell. 1995;80:795-803.
19. Schott J, Charpentier F, Peltier S, Foley P, Drouin E, Bouhour J, Donnelly P, Vergnaud G, Bachner L, Moisan J, LeMarec H, Pascal O. Mapping of a gene for long QT syndrome to chromosome 4q25-27. Am J Hum Genet. 1995;57:1114-1122.
20. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS. Diagnostic criteria for the long QT syndrome: an update. Circulation. 1993;88:782-784.
21. Gorgels APM, Al-Fadley F, Zaman L, Kantoch MJ, Al-Halees Z. The long QT syndrome with impaired atrioventricular conduction: a malignant variant in infants. J Cardiovasc Electrophysiol. 1998;9: 1225-1232.
22. Krahn AD, Klein GJ, Yee R. Hysteresis of the RT interval with exercise: a new marker for the long-QT syndrome? Circulation. 1997;96: 1551-1556.
23. Drici M, Arrighi I, Chouabe C, Mann JR, Lazdunski M, Romey G, Barhanin J. Involvement of IsK-associated K channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome. Circ Res. 1998;83:95-102.
24. Babij P, Askew GR, Nieuwenhuijsen B, Su C, Bridal TR, Jow B, Argentieri TM, Kulik J, DeGennaro LJ, Spinelli W, Colatsky TJ. Inhibition of cardiac delayed rectifier K current by overexpression of the long-QT syndrome HERG G628S mutation in transgenic mice. Circ Res. 1998;83:668-678.
25. Barry DM, Xu H, Schuessler RB, Nerbonne JM. Functional knockout of the transient outward current, long QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 α subunit. Circ Res. 1998; 83:560-567.