Oxidized calmodulin kinase II regulates conduction following myocardial infarction: A computational analysis

PLoS Computational Biology

Volumn 5, Issue 12, 2009, Pages

  Christensen, Matthew D ^a   Dun, Wen ^b   Boyden, Penelope A ^b   Anderson, Mark E ^a   Mohler, Peter J ^a   Hund, Thomas J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALMODULIN; CARDIOLOGY; CELL DEATH; CHEMICAL ACTIVATION; DISEASES; ENZYMES; HEART;

ACTIVATION PATHWAY; CALCIUM CYCLING; CALMODULIN KINASE II; COMPUTATIONAL ANALYSIS; CONDUCTION BLOCK; CRITICAL SIGNALING PATHWAYS; DIVERGENTS; HEART DISEASE; MYOCARDIAL INFARCTION; SIGNALLING PATHWAYS;

OXIDATION;

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; COMPUTER SIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EXPERIMENTAL DOG; HEART BLOCK; HEART INFARCTION; HEART MUSCLE CONDUCTION SYSTEM; HEART PROARRHYTHMIA; MATHEMATICAL MODEL; NONHUMAN; OXIDATION; REENTRY TACHYCARDIA; ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; DISEASE MODEL; DOG; ENZYMOLOGY; IMMUNOBLOTTING; METABOLISM; METHODOLOGY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REPRODUCIBILITY;

ANIMALIA;

ACTION POTENTIALS; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; DOGS; HEART CONDUCTION SYSTEM; IMMUNOBLOTTING; MODELS, BIOLOGICAL; MYOCARDIAL INFARCTION; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHORYLATION; REPRODUCIBILITY OF RESULTS; SODIUM CHANNELS;

EID: 74549157674     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000583     Document Type: Article

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