Reactive oxygen species suppress cardiac Na V1.5 expression through Foxo1

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Mao, Weike ^a,e   You, Tao ^a,b   Ye, Bo ^a   Li, Xiang ^a   Dong, Henry H ^c   Hill, Joseph A ^d   Li, Faqian ^a   Xu, Haodong ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SODIUM CHANNEL NAV1.5; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; OXIDIZING AGENT; SODIUM CHANNEL; SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; HEART MUSCLE CELL; HELA CELL; HUMAN; INSULIN RESPONSE ELEMENT; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SCN5A GENE; SEMI QUANTITATIVE REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM CURRENT; ANIMAL; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; SEQUENCE HOMOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

RATTUS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL NUCLEUS; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; MICE; MYOCYTES, CARDIAC; OXIDANTS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SODIUM CHANNELS;

EID: 84857665522     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032738     Document Type: Article

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