Functionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel - an overview of the current mutational data

Molecular Pain

Volumn 9, Issue 1, 2013, Pages

  Winter, Zoltán ^a   Buhala, Andrea ^a   Ötvös, Ferenc ^b   Jósvay, Katalin ^a,b   Vizler, Csaba ^b   Dombi, György ^a   Szakonyi, Gerda ^a   Oláh, Zoltán ^a,c  

^a UNIVERSITY OF SZEGED   (Hungary)

^b INSTITUTE OF BIOCHEMISTRY   (Hungary)

^c Acheuron Hungary Ltd   (Hungary)

Author keywords

Amino acid; Molecular modelling; Mutants; Structure; TRPV1; Vanilloid

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ADENOSINE TRIPHOSPHATE; ALLICIN; ANANDAMIDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN; CAPSAICIN; CHOLESTEROL; DOPAMINE DERIVATIVE; N ARACHIDONOYLDOPAMINE; REDUCING AGENT; RESINIFERATOXIN; SPIDER VENOM; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST; VANILLOID RECEPTOR AGONIST;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; CHANNEL GATING; COMPUTER MODEL; DELETION MUTANT; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG TARGETING; ELECTRIC POTENTIAL; GENE EXPRESSION; GENE FUNCTION; GENE STRUCTURE; GLYCOSYLATION; HUMAN; MUTATIONAL ANALYSIS; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RESIDUE ANALYSIS; REVIEW; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; TRPV1 GENE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; HUMANS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; RATS; TRPV CATION CHANNELS;

EID: 84879075593     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-9-30     Document Type: Review

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