A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis

Arthritis and Rheumatism

Volumn 63, Issue 3, 2011, Pages 819-829

  Fernandes, Elizabeth S ^a   Russell, Fiona A ^a   Spina, Domenico ^a   McDougall, Jason J ^b   Graepel, Rabea ^a   Gentry, Clive ^a   Staniland, Amelia A ^a   Mountford, David M ^a   Keeble, Julie E ^a   Malcangio, Marzia ^a   Bevan, Stuart ^a   Brain, Susan D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; AP 18; FREUND ADJUVANT; INDOMETACIN; PROSTAGLANDIN SYNTHASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HISTOPATHOLOGY; HYPERALGESIA; INFLAMMATORY HYPERALGESIA; JOINT SWELLING; KNEE ARTHRITIS; MALE; MECHANICAL HYPERALGESIA; MONARTHRITIS; MOUSE; NOCICEPTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; WILD TYPE;

ADJUVANTS, IMMUNOLOGIC; ANILIDES; ANIMALS; ARTHRALGIA; ARTHRITIS, EXPERIMENTAL; CINNAMATES; DISEASE MODELS, ANIMAL; FEMALE; FREUND'S ADJUVANT; HYPERALGESIA; INJECTIONS, INTRA-ARTICULAR; INJECTIONS, SPINAL; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPV CATION CHANNELS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79953678388     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30150     Document Type: Article

References (50)

1. Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 1991;43: 143-201.
2. Cho WG, Valtschanoff JG. Vanilloid receptor TRPV1-positive sensory afferents in the mouse ankle and knee joints. Brain Res 2008;1219:59-65.
3. Fernihough J, Gentry C, Bevan S, Winter J. Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis. Neurosci Lett 2005;388:75-80. (Pubitemid 41206735)
4. Schaible HG, Schmidt RF. Neurophysiology of chronic inflammatory pain: electrophysiological recordings from spinal cord neurons in rats with prolonged acute and chronic unilateral inflammation at the ankle. Prog Brain Res 1996;110:167-76. (Pubitemid 27048986)
5. Szallasi A, Cruz F, Geppetti P. TRPV1: a therapeutic target for novel analgesic drugs? Trends Mol Med 2006;12:545-54. (Pubitemid 44633805)
6. Stucky CL, Dubin AE, Jeske NA, Malin SA, McKemy DD, Story GM. Roles of transient receptor potential channels in pain. Brain Res Rev 2009;60:2-23.
7. Barton NJ, McQueen DS, Thomson D, Gauldie SD, Wilson AW, Salter DM, et al. Attenuation of experimental arthritis in TRPV1R knockout mice. Exp Mol Pathol 2006;81:166-70. (Pubitemid 44715790)
8. Bolcskei K, Helyes Z, Szabo A, Sandor K, Elekes K, Nemeth J, et al. Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice. Pain 2005;117:368-76. (Pubitemid 41386528)
9. Chen Y, Willcockson HH, Valtschanoff JG. Increased expression of CGRP in sensory afferents of arthritic mice: effect of genetic deletion of the vanilloid receptor TRPV1. Neuropeptides 2008;42: 551-6.
10. Keeble J, Russell F, Curtis B, Starr A, Pinter E, Brain SD. Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation. Arthritis Rheum 2005;52:3248-56. (Pubitemid 41447108)
11. Szabo A, Helyes Z, Sandor K, Bite A, Pinter E, Nemeth J, et al. Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient mice. J Pharmacol Exp Ther 2005;314:111-9. (Pubitemid 41058247)
12. Ignatavicius DD. Rheumatoid arthritis and the older adult. Geri-atr Nurs 2001;22:139-42. (Pubitemid 33379769)
13. Breedveld F.Multiple faces of rheumatoid arthritis: diagnostic and therapeutic algorithms. Autoimmun Rev 2004;3 Suppl 1:S22.
14. Rankin EC, Choy EH, Kassimos D, Kingsley GH, Sopwith AM, Isenberg DA, et al. The therapeutic effects of an engineered human anti-tumour necrosis factor α antibody (CDP571) in rheumatoid arthritis. Br J Rheumatol 1995;34:334-42.
15. Inglis JJ, Notley CA, Essex D, Wilson AW, Feldmann M, Anand P, et al. Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade. Arthritis Rheum 2007;56:4015-23. (Pubitemid 350262329)
16. Boettger MK, Hensellek S, Richter F, Gajda M, Stockigt R, von Banchet GS, et al. Antinociceptive effects of tumor necrosis factor α neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target. Arthritis Rheum 2008;58:2368-78.
17. Russell FA, Fernandes ES, Courade JP, Keeble JE, Brain SD. Tumour necrosis factor α mediates transient receptor potential vanilloid 1-dependent bilateral thermal hyperalgesia with distinct peripheral roles of interleukin-1beta;, protein kinase C and cyclooxy-genase-2 signalling. Pain 2009;142:264-74.
18. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 2000;288:241-2.
19. Kanai Y, Nakazato E, Fujiuchi A, Hara T, Imai A. Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical hyperalgesia of CCI rats. Neuropharmacology 2005; 49:977-84. (Pubitemid 41503297)
20. Kanai Y, Hara T, Imai A, Sakakibara A. Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia. J Pharm Pharmacol 2007;59:733-8. (Pubitemid 47051117)
21. Cui M, Honore P, Zhong C, Gauvin D, Mikusa J, Hernandez G, et al. TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists. J Neurosci 2006;26:9385-93. (Pubitemid 44396851)
22. Andersson DA, Gentry C, Moss S, Bevan S. Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress. J Neurosci 2008;28:2485-94. (Pubitemid 351348185)
23. Kochukov MY, McNearney TA, Fu Y, Westlund KN. Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes. Am J Physiol Cell Physiol 2006;291:C424-32. (Pubitemid 44343625)
24. Keeble JE, Bodkin JV, Liang L, Wodarski R, Davies M, Fernandes ES, et al. Hydrogen peroxide is a novel mediator of inflammatory hyperalgesia, acting via transient receptor potential vanilloid 1-dependent and independent mechanisms. Pain 2009; 141:135-42.
25. Petrus M, Peier AM, Bandell M, Hwang SW, Huynh T, Olney N, et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain 2007;3:40-7.
26. Eid SR, Crown ED, Moore EL, Liang HA, Choong KC, Dima S, et al. HC-030031, a TRPA1 selective antagonist, attenuates in-flammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain 2008;4:48-57.
27. Kidd BL. What are the mechanisms of regional musculoskeletal pain? Baillieres Best Pract Res Clin Rheumatol 1999;13:217-30. (Pubitemid 29353724)
28. Zangger P, Keystone EC, Bogoch ER. Asymmetry of small joint involvement in rheumatoid arthritis: prevalence and tendency towards symmetry over time. Joint Bone Spine 2005;72:241-7. (Pubitemid 40591765)
29. Clark N, Keeble J, Fernandes ES, Starr A, Liang L, Sugden D, et al. The transient receptor potential vanilloid 1 (TRPV1) receptor protects against the onset of sepsis after endotoxin. FASEB J 2007;21:3747-55. (Pubitemid 350075162)
30. Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, Woolf CJ, et al. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 2006;50:277-89.
31. Grant AD, Pinter E, Salmon AM, Brain SD. An examination of neurogenic mechanisms involved in mustard oil-induced inflammation in the mouse. Eur J Pharmacol 2005;507:273-80. (Pubitemid 40126864)
32. Costa R, Marotta DM, Manjavachi MN, Fernandes ES, Lima-Garcia JF, Paszcuk AF, et al. Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice. Br J Pharmacol 2008;154:1094-103. (Pubitemid 351915068)
33. Mogil JS. The genetic mediation of individual differences in sensitivity to pain and its inhibition. Proc Natl Acad Sci USA 1999;96:7744-51. (Pubitemid 29328352)
34. Mogil JS, Adhikari SM. Hot and cold nociception are genetically correlated. J Neurosci 1999;19:RC25.
35. Kerr BJ, David S. Pain behaviors after spinal cord contusion injury in two commonly used mouse strains. Exp Neurol 2007;206:240-7. (Pubitemid 47094766)
36. Mogil JS, Miermeister F, Seifert F, Strasburg K, Zimmermann K, Reinold H, et al. Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. Proc Natl Acad Sci U S A 2005;102:12938-43. (Pubitemid 41279468)
37. Nicol GD, Lopshire JC, Pafford CM. Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons. J Neurosci 1997;17:975-82. (Pubitemid 27043956)
38. Khan AA, Diogenes A, Jeske NA, Henry MA, Akopian A, Hargreaves KM. Tumor necrosis factor α enhances the sensitivity of rat trigeminal neurons to capsaicin. Neuroscience 2008;155: 503-9.
39. Jin X, Gereau RW 4th. Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-α. J Neurosci 2006;26:246-55. (Pubitemid 43089538)
40. Mormina ME, Thakur S, Molleman A, Whelan CJ, Baydoun AR. Cannabinoid signalling in TNF-α induced IL-8 release. Eur J Pharmacol 2006;540:183-90. (Pubitemid 43866696)
41. Nilsson O, Fowler CJ, Jacobsson SO. The cannabinoid agonist WIN 55,212-2 inhibits TNF-α-induced neutrophil transmigration across ECV304 cells. Eur J Pharmacol 2006;547:165-73. (Pubitemid 44373900)
42. Rettori V, Fernandez-Solari J, Prestifilippo JP, Mohn C, De Laurentiis A, Bornstein SR, et al. Endocannabinoids in TNF-α and ethanol actions. Neuroimmunomodulation 2007;14:188-92.
43. Lappin SC, Randall AD, Gunthorpe MJ, Morisset V. TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation. Eur J Pharmacol 2006;540:73-81. (Pubitemid 44177497)
44. Bautista DM, Jordt SE, Nikai T, Tsuruda PR, Read AJ, Poblete J, et al. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 2006;124:1269-82.
45. Wei H, Chapman H, Saarnilehto M, Kuokkanen K, Koivisto A, Pertovaara A. Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat. Neuropharmacology 2010;58:578-84.
46. 2 via activation of ion channel TRPA1. Mol Pain 2008;4:30-8.
47. Materazzi S, Nassini R, Andre E, Campi B, Amadesi S, Trevisani M, et al. Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A 2008;105:12045-50.
48. Mirshafiey A, Mohsenzadegan M. The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis. Iran J Allergy Asthma Immunol 2008;7:195-202.
49. Holzer P. The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor. Br J Pharmacol 2008;155:1145-62.
50. Khairatkar-Joshi N, Szallasi A. TRPV1 antagonists: the challenges for therapeutic targeting. Trends Mol Med 2009;15:14-22.