Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 3, 2002, Pages 1052-1060

  Seabrook, Guy R ^a   Sutton, Kathy G ^a   Jarolimek, Wolfgang ^a   Hollingworth, Gregory J ^a   Teague, Simon ^a   Webb, Janine ^a   Clark, Natalie ^a   Boyce, Susan ^a   Kerby, Julie ^a   Ali, Zahid ^a   Chou, Margaret ^b   Middleton, Richard ^b   Kaczorowski, Gregory ^b   Jones, A Brian ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; CAPSAZEPINE; IODORESINIFERATOXIN; PROTON; RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; VANILLOID 1 RECEPTOR ANTAGONIST; VANILLOID RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; GENETIC TRANSFECTION; HEAT; HUMAN; HUMAN CELL; IC 50; ION CURRENT; MALE; NERVE FIBER; NOCICEPTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ACTION POTENTIALS; ANIMALS; CANNABINOIDS; CAPSAICIN; CHO CELLS; CRICETINAE; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DRUG;

EID: 0036894895     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.040394     Document Type: Article

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