-
1
-
-
77249125805
-
The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation
-
Alawi K and Keeble J (2010) The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation. Pharmacol Ther 125:181-195
-
(2010)
Pharmacol Ther
, vol.125
, pp. 181-195
-
-
Alawi, K.1
Keeble, J.2
-
2
-
-
80054934570
-
Determination of capsaicin and dihydrocapsaicin in Capsicum fruit samples using high performance liquid chromatography
-
Al Othman ZA, Ahmed YB, Habila MA, and Ghafar AA (2011) Determination of capsaicin and dihydrocapsaicin in Capsicum fruit samples using high performance liquid chromatography. Molecules 16:8919-8929
-
(2011)
Molecules
, vol.16
, pp. 8919-8929
-
-
Al Othman, Z.A.1
Ahmed, Y.B.2
Habila, M.A.3
Ghafar, A.A.4
-
3
-
-
79551672861
-
Pain sensitivity and experimentally induced sensitisation in red haired females
-
Andresen T, Lunden D, Drewes AM, and Arendt-Nielsen L (2011) Pain sensitivity and experimentally induced sensitisation in red haired females. Scand J Pain 2:3-6
-
(2011)
Scand J Pain
, vol.2
, pp. 3-6
-
-
Andresen, T.1
Lunden, D.2
Drewes, A.M.3
Arendt-Nielsen, L.4
-
4
-
-
33947331049
-
A Human experimental pain models in drug development: Translational pain research
-
Arendt-Nielsen L, Curatolo M, and Drewes A (2007) A Human experimental pain models in drug development: translational pain research. Curr Opin Investig Drugs 8:41-53
-
(2007)
Curr Opin Investig Drugs
, vol.8
, pp. 41-53
-
-
Arendt-Nielsen, L.1
Curatolo, M.2
Drewes, A.3
-
5
-
-
43049113946
-
Viscero-somatic reflexes in referred pain areas evoked by capsaicin stimulation of the human gut
-
Arendt-Nielsen L, Schipper KP, Dimcevski G, Sumikura H, Krarup AL, Giamberardino MA, and Drewes AM (2008a) Viscero-somatic reflexes in referred pain areas evoked by capsaicin stimulation of the human gut. Eur J Pain 12:544-551
-
(2008)
Eur J Pain
, vol.12
, pp. 544-551
-
-
Arendt-Nielsen, L.1
Schipper, K.P.2
Dimcevski, G.3
Sumikura, H.4
Krarup, A.L.5
Giamberardino, M.A.6
Drewes, A.M.7
-
6
-
-
42749090283
-
Interactions between glutamate and capsaicin in inducing muscle pain and sensitization in humans
-
Arendt-Nielsen L, Svensson P, Sessle BJ, Cairns BE, and Wang K (2008b) Interactions between glutamate and capsaicin in inducing muscle pain and sensitization in humans. Eur J Pain 12:661-670
-
(2008)
Eur J Pain
, vol.12
, pp. 661-670
-
-
Arendt-Nielsen, L.1
Svensson, P.2
Sessle, B.J.3
Cairns, B.E.4
Wang, K.5
-
7
-
-
67349094007
-
Experimental and clinical applications of quantitative sensory testing applied to skin, muscles and viscera
-
Arendt-Nielsen L and Yarnitsky D (2009) Experimental and clinical applications of quantitative sensory testing applied to skin, muscles and viscera. J Pain 10:556-572
-
(2009)
J Pain
, vol.10
, pp. 556-572
-
-
Arendt-Nielsen, L.1
Yarnitsky, D.2
-
8
-
-
58849127305
-
Effect of capsaicinevoked jaw-muscle pain on intramuscular blood-flow
-
Arima T, Arendt-Nielsen L, Minagi S, and Svensson P (2009) Effect of capsaicinevoked jaw-muscle pain on intramuscular blood-flow. Arch Oral Biol 54:241-249
-
(2009)
Arch Oral Biol
, vol.54
, pp. 241-249
-
-
Arima, T.1
Arendt-Nielsen, L.2
Minagi, S.3
Svensson, P.4
-
9
-
-
0034208817
-
Capsaicin-induced muscle hyperalgesia in the exercised and non-exercised human masseter muscle
-
Arima T, Svensson P, and Arendt-Nielsen L (2000) Capsaicin-induced muscle hyperalgesia in the exercised and non-exercised human masseter muscle. J Orofac Pain 14:213-223
-
(2000)
J Orofac Pain
, vol.14
, pp. 213-223
-
-
Arima, T.1
Svensson, P.2
Arendt-Nielsen, L.3
-
10
-
-
68449096248
-
Pharmacokinetic analysis of capsaicin after topical administration of a high-concentration capsaicin patch to patients with peripheral neuropathic pain
-
Babbar S, Marier JF, Mouksassi MS, Beliveau M, Vanhove GF, Chanda S, and Bley K (2009) Pharmacokinetic analysis of capsaicin after topical administration of a high-concentration capsaicin patch to patients with peripheral neuropathic pain. Ther Drug Monit 31:502-510
-
(2009)
Ther Drug Monit
, vol.31
, pp. 502-510
-
-
Babbar, S.1
Marier, J.F.2
Mouksassi, M.S.3
Beliveau, M.4
Vanhove, G.F.5
Chanda, S.6
Bley, K.7
-
11
-
-
55549129906
-
NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: A randomised, double-blind study
-
and NGX-4010 C116 Study Group
-
Backonja M, Wallace MS, Blonsky ER, Cutler BJ, Malan P Jr, Rauck R, Tobias J, and NGX-4010 C116 Study Group (2008) NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study. Lancet Neurol 7:1106-1112
-
(2008)
Lancet Neurol
, vol.7
, pp. 1106-1112
-
-
Backonja, M.1
Wallace, M.S.2
Blonsky, E.R.3
Cutler, B.J.4
Malan Jr., P.5
Rauck, R.6
Tobias, J.7
-
12
-
-
70349440715
-
Preclinical and early clinical investigations related to monoaminergic pain modulation
-
Bannister K, Bee LA, and Dickenson AH (2009) Preclinical and early clinical investigations related to monoaminergic pain modulation. Neurotherapeutics 6:703-712
-
(2009)
Neurotherapeutics
, vol.6
, pp. 703-712
-
-
Bannister, K.1
Bee, L.A.2
Dickenson, A.H.3
-
13
-
-
20844446302
-
Effects of capsaicin on visceral smooth muscle: A valuable tool for sensory neurotransmitter identification
-
Barthó L, Benkó R, Patacchini R, Pethö G, Holzer-Petsche U, Holzer P, Lázár Z, Undi S, Illényi L, Antal A, et al. (2004) Effects of capsaicin on visceral smooth muscle: a valuable tool for sensory neurotransmitter identification. Eur J Pharmacol 500:143-157
-
(2004)
Eur J Pharmacol
, vol.500
, pp. 143-157
-
-
Barthó, L.1
Benkó, R.2
Patacchini, R.3
Pethö, G.4
Holzer-Petsche, U.5
Holzer, P.6
Lázár, Z.7
Undi, S.8
Illényi, L.9
Antal, A.10
-
14
-
-
0025744356
-
Neurogenic hyperalgesia: The search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia
-
Baumann TK, Simone DA, Shain CN, and LaMotte RH (1991) Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia. J Neurophysiol 66:212-227
-
(1991)
J Neurophysiol
, vol.66
, pp. 212-227
-
-
Baumann, T.K.1
Simone, D.A.2
Shain, C.N.3
Lamotte, R.H.4
-
15
-
-
57049155037
-
Studies of the toxicological potential of capsinoids: X. Safety assessment and pharmacokinetics of capsinoids in healthy male volunteers after a single oral ingestion of CH-19 Sweet extract
-
Bernard BK, Tsubuku S, Kayahara T, Maeda K, Hamada M, Nakamura T, Shirai Y, Nakayama A, Ueno S, and Mihara R (2008) Studies of the toxicological potential of capsinoids: X. Safety assessment and pharmacokinetics of capsinoids in healthy male volunteers after a single oral ingestion of CH-19 Sweet extract. Int J Toxicol 27 (Suppl 3):137-147
-
(2008)
Int J Toxicol
, vol.27
, Issue.SUPPL. 3
, pp. 137-147
-
-
Bernard, B.K.1
Tsubuku, S.2
Kayahara, T.3
Maeda, K.4
Hamada, M.5
Nakamura, T.6
Shirai, Y.7
Nakayama, A.8
Ueno, S.9
Mihara, R.10
-
16
-
-
0025328825
-
Sensory neuron-specific actions of capsaicin: Mechanisms and applications
-
Bevan S and Szolcsányi J (1990) Sensory neuron-specific actions of capsaicin: mechanisms and applications. Trends Pharmacol Sci 11:330-333
-
(1990)
Trends Pharmacol Sci
, vol.11
, pp. 330-333
-
-
Bevan, S.1
Szolcsányi, J.2
-
17
-
-
0142059776
-
Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
-
Bhave G, Hu HJ, Glauner KS, Zhu W, Wang H, Brasier DJ, Oxford GS, and Gereau RW 4th (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci USA 100:12480-12485
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12480-12485
-
-
Bhave, G.1
Hu, H.J.2
Glauner, K.S.3
Zhu, W.4
Wang, H.5
Brasier, D.J.6
Oxford, G.S.7
Gereau IV, R.W.8
-
18
-
-
79953193743
-
Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients
-
Binder A, May D, Baron R, Maier C, Tölle TR, Treede RD, Berthele A, Faltraco F, Flor H, Gierthmühlen J, et al. (2011) Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients. PLoS One 6:e17387
-
(2011)
PLoS One
, vol.6
-
-
Binder, A.1
May, D.2
Baron, R.3
Maier, C.4
Tölle, T.R.5
Treede, R.D.6
Berthele, A.7
Faltraco, F.8
Flor, H.9
Gierthmühlen, J.10
-
19
-
-
84861754967
-
Role of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions
-
Brenchat A, Zamanillo D, Hamon M, Romero L, and Vela JM (2012) Role of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions. Eur J Pain 16:72-81
-
(2012)
Eur J Pain
, vol.16
, pp. 72-81
-
-
Brenchat, A.1
Zamanillo, D.2
Hamon, M.3
Romero, L.4
Vela, J.M.5
-
20
-
-
59049083447
-
5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice
-
Brenchat A, Romero L, García M, Pujol M, Burgueñ O J, Torrens A, Hamon M, Baeyens JM, Buschmann H, Zamanillo D, et al. (2009) 5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice. Pain 141:239-247
-
(2009)
Pain
, vol.141
, pp. 239-247
-
-
Brenchat, A.1
Romero, L.2
García, M.3
Pujol, M.4
Burgueñ, O.J.5
Torrens, A.6
Hamon, M.7
Baeyens, J.M.8
Buschmann, H.9
Zamanillo, D.10
-
21
-
-
77049088507
-
Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus
-
Brock C, Andresen T, Frøkjaer JB, Gale J, Olesen AE, Arendt-Nielsen L, and Drewes AM (2010) Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus. Eur J Pain 14:273-281
-
(2010)
Eur J Pain
, vol.14
, pp. 273-281
-
-
Brock, C.1
Andresen, T.2
Frøkjaer, J.B.3
Gale, J.4
Olesen, A.E.5
Arendt-Nielsen, L.6
Drewes, A.M.7
-
23
-
-
33644625829
-
Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males
-
Cairns BE, Svensson P, Wang K, Castrillon E, Hupfeld S, Sessle BJ, and Arendt- Nielsen L (2006) Ketamine attenuates glutamate-induced mechanical sensitization of the masseter muscle in human males. Exp Brain Res 169:467-472
-
(2006)
Exp Brain Res
, vol.169
, pp. 467-472
-
-
Cairns, B.E.1
Svensson, P.2
Wang, K.3
Castrillon, E.4
Hupfeld, S.5
Sessle, B.J.6
Arendt-Nielsen, L.7
-
24
-
-
77956235414
-
Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma
-
Cantero-Recasens G, Gonzalez JR, Fandos C, Duran-Tauleria E, Smit LA, Kauffmann F, Antó JM, and Valverde MA (2010) Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma. J Biol Chem 285:27532-27535
-
(2010)
J Biol Chem
, vol.285
, pp. 27532-27535
-
-
Cantero-Recasens, G.1
Gonzalez, J.R.2
Fandos, C.3
Duran-Tauleria, E.4
Smit, L.A.5
Kauffmann, F.6
Antó, J.M.7
Valverde, M.A.8
-
25
-
-
43049181939
-
Glutamate-evoked jaw muscle pain as a model of persistent myofascial TMD pain?
-
Castrillon EE, Cairns BE, Ernberg M, Wang K, Sessle B, Arendt-Nielsen L, and Svensson P (2008a) Glutamate-evoked jaw muscle pain as a model of persistent myofascial TMD pain? Arch Oral Biol 53:666-676
-
(2008)
Arch Oral Biol
, vol.53
, pp. 666-676
-
-
Castrillon, E.E.1
Cairns, B.E.2
Ernberg, M.3
Wang, K.4
Sessle, B.5
Arendt-Nielsen, L.6
Svensson, P.7
-
26
-
-
44849106902
-
Effect of peripheral NMDA receptor blockade with ketamine on chronic myofascial pain in temporomandibular disorder patients: A randomized, double-blinded, placebo-controlled trial
-
Castrillon EE, Cairns BE, Ernberg M, Wang K, Sessle BJ, Arendt-Nielsen L, and Svensson P (2008b) Effect of peripheral NMDA receptor blockade with ketamine on chronic myofascial pain in temporomandibular disorder patients: a randomized, double-blinded, placebo-controlled trial. J Orofac Pain 22:122-130
-
(2008)
J Orofac Pain
, vol.22
, pp. 122-130
-
-
Castrillon, E.E.1
Cairns, B.E.2
Ernberg, M.3
Wang, K.4
Sessle, B.J.5
Arendt-Nielsen, L.6
Svensson, P.7
-
27
-
-
33846149200
-
Transient receptor potential ion channels as participants in thermosensation and thermoregulation
-
Caterina MJ (2007) Transient receptor potential ion channels as participants in thermosensation and thermoregulation. Am J Physiol Regul Integr Comp Physiol 292:R64-R76
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
-
-
Caterina, M.J.1
-
28
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, and Julius D (2000) Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288:306-313
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.B.3
Martin, W.J.4
Trafton, J.5
Petersen-Zeitz, K.R.6
Koltzenburg, M.7
Basbaum, A.I.8
Julius, D.9
-
29
-
-
0033119629
-
A capsaicinreceptor homologue with a high threshold for noxious heat
-
Caterina MJ, Rosen TA, Tominaga M, Brake AJ, and Julius D (1999) A capsaicinreceptor homologue with a high threshold for noxious heat. Nature 398:436-441
-
(1999)
Nature
, vol.398
, pp. 436-441
-
-
Caterina, M.J.1
Rosen, T.A.2
Tominaga, M.3
Brake, A.J.4
Julius, D.5
-
30
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, and Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
31
-
-
59649102231
-
Pharmacokinetic and the effect of capsaicin in Capsicum frutescens on decreasing plasma glucose level
-
Chaiyasit K, Khovidhunkit W, and Wittayalertpanya S (2009) Pharmacokinetic and the effect of capsaicin in Capsicum frutescens on decreasing plasma glucose level. J Med Assoc Thai 92:108-113
-
(2009)
J Med Assoc Thai
, vol.92
, pp. 108-113
-
-
Chaiyasit, K.1
Khovidhunkit, W.2
Wittayalertpanya, S.3
-
32
-
-
0037309871
-
Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency
-
Chan CL, Facer P, Davis JB, Smith GD, Egerton J, Bountra C, Williams NS, and Anand P (2003) Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency. Lancet 361:385-391
-
(2003)
Lancet
, vol.361
, pp. 385-391
-
-
Chan, C.L.1
Facer, P.2
Davis, J.B.3
Smith, G.D.4
Egerton, J.5
Bountra, C.6
Williams, N.S.7
Anand, P.8
-
33
-
-
41549161583
-
In vitro hepatic and skin metabolism of capsaicin
-
Chanda S, Bashir M, Babbar S, Koganti A, and Bley K (2008) In vitro hepatic and skin metabolism of capsaicin. Drug Metab Dispos 36:670-675
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 670-675
-
-
Chanda, S.1
Bashir, M.2
Babbar, S.3
Koganti, A.4
Bley, K.5
-
34
-
-
0347511640
-
Comparative EEG activation to skin pain and muscle pain induced by capsaicin injection
-
Chang PF, Arendt-Nielsen L, Graven-Nielsen T, Svensson P, and Chen AC (2004) Comparative EEG activation to skin pain and muscle pain induced by capsaicin injection. Int J Psychophysiol 51:117-126
-
(2004)
Int J Psychophysiol
, vol.51
, pp. 117-126
-
-
Chang, P.F.1
Arendt-Nielsen, L.2
Graven-Nielsen, T.3
Svensson, P.4
Chen, A.C.5
-
35
-
-
33845343959
-
Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1
-
Christoph T, Gillen C, Mika J, Grünweller A, Schäfer MK, Schiene K, Frank R, Jostock R, Bahrenberg G, Weihe E, et al. (2007) Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1 Neurochem Int 50: 281-290
-
(2007)
Neurochem Int
, vol.50
, pp. 281-290
-
-
Christoph, T.1
Gillen, C.2
Mika, J.3
Grünweller, A.4
Schäfer, M.K.5
Schiene, K.6
Frank, R.7
Jostock, R.8
Bahrenberg, G.9
Weihe, E.10
-
36
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham DE (2003) TRP channels as cellular sensors. Nature 426:517-524
-
(2003)
Nature
, vol.426
, pp. 517-524
-
-
Clapham, D.E.1
-
37
-
-
34247472646
-
Attenuated cold sensitivity in TRPM8 null mice
-
Colburn RW, Lubin ML, Stone DJ, Jr., Wang Y, Lawrence D, D'Andrea MR, Brandt MR, Liu Y, Flores CM, and Qin N (2007) Attenuated cold sensitivity in TRPM8 null mice. Neuron 54:379-386
-
(2007)
Neuron
, vol.54
, pp. 379-386
-
-
Colburn, R.W.1
Lubin, M.L.2
Stone Jr., D.J.3
Wang, Y.4
Lawrence, D.5
D'Andrea, M.R.6
Brandt, M.R.7
Liu, Y.8
Flores, C.M.9
Qin, N.10
-
38
-
-
0014683485
-
Abnormal electroretinogram from a Drosophila mutant
-
Cosens DJ and Manning A (1969) Abnormal electroretinogram from a Drosophila mutant. Nature 224:285-287
-
(1969)
Nature
, vol.224
, pp. 285-287
-
-
Cosens, D.J.1
Manning, A.2
-
39
-
-
33748680717
-
TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists
-
Cui M, Honore P, Zhong C, Gauvin D, Mikusa J, Hernandez G, Chandran P, Gomtsyan A, Brown B, Bayburt EK, et al. (2006) TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists. J Neurosci 26:9385-9393
-
(2006)
J Neurosci
, vol.26
, pp. 9385-9393
-
-
Cui, M.1
Honore, P.2
Zhong, C.3
Gauvin, D.4
Mikusa, J.5
Hernandez, G.6
Chandran, P.7
Gomtsyan, A.8
Brown, B.9
Bayburt, E.K.10
-
40
-
-
0027269633
-
The effect of pre- versus postinjury infiltration with lidocaine on thermal and mechanical hyperalgesia after heat injury to the skin
-
Dahl JB, Brennum J, Arendt-Nielsen L, Jensen TS, and Kehlet H (1993) The effect of pre- versus postinjury infiltration with lidocaine on thermal and mechanical hyperalgesia after heat injury to the skin. Pain 53:43-51
-
(1993)
Pain
, vol.53
, pp. 43-51
-
-
Dahl, J.B.1
Brennum, J.2
Arendt-Nielsen, L.3
Jensen, T.S.4
Kehlet, H.5
-
42
-
-
34247487011
-
TRPM8 is required for cold sensation in mice
-
Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, and Patapoutian A (2007) TRPM8 is required for cold sensation in mice. Neuron 54:371-378
-
(2007)
Neuron
, vol.54
, pp. 371-378
-
-
Dhaka, A.1
Murray, A.N.2
Mathur, J.3
Earley, T.J.4
Petrus, M.J.5
Patapoutian, A.6
-
44
-
-
0025131647
-
Antinociception produced by capsaicin: Spinal or peripheral mechanism?
-
Dickenson A, Ashwood N, Sullivan AF, James I, and Dray A (1990) Antinociception produced by capsaicin: spinal or peripheral mechanism? Eur J Pharmacol 187: 225-233
-
(1990)
Eur J Pharmacol
, vol.187
, pp. 225-233
-
-
Dickenson, A.1
Ashwood, N.2
Sullivan, A.F.3
James, I.4
Dray, A.5
-
45
-
-
0037397757
-
The heat/capsaicin sensitization model: A methodologic study
-
Dirks J, Petersen KL, and Dahl JB (2003) The heat/capsaicin sensitization model: a methodologic study. J Pain 4:122-128
-
(2003)
J Pain
, vol.4
, pp. 122-128
-
-
Dirks, J.1
Petersen, K.L.2
Dahl, J.B.3
-
46
-
-
0029965156
-
Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
-
Docherty RJ, Yeats JC, Bevan S, and Boddeke HW (1996) Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats. Pflugers Arch 431:828-837
-
(1996)
Pflugers Arch
, vol.431
, pp. 828-837
-
-
Docherty, R.J.1
Yeats, J.C.2
Bevan, S.3
Boddeke, H.W.4
-
47
-
-
1642286206
-
The vanilloid receptor-1 (TRPV1) is expressed in some rat dorsal horn NK1 cells
-
Doly S, Fischer J, and Conrath M (2004a) The vanilloid receptor-1 (TRPV1) is expressed in some rat dorsal horn NK1 cells. Brain Res 1004:203-207
-
(2004)
Brain Res
, vol.1004
, pp. 203-207
-
-
Doly, S.1
Fischer, J.2
Conrath, M.3
-
48
-
-
1242292301
-
The vanilloid receptor-1 is expressed in rat spinal dorsal horn astrocytes
-
Doly S, Fischer J, Salio C, and Conrath M (2004b) The vanilloid receptor-1 is expressed in rat spinal dorsal horn astrocytes. Neurosci Lett 357:123-126
-
(2004)
Neurosci Lett
, vol.357
, pp. 123-126
-
-
Doly, S.1
Fischer, J.2
Salio, C.3
Conrath, M.4
-
49
-
-
33751099585
-
B1 and TRPV-1 receptor genes and their relationship to hyperalgesia following spinal cord injury
-
DomBourian MG, Turner NA, Gerovac TA, Vemuganti R, Miranpuri GS, Türeyen K, Satriotomo I, Miletic V, and Resnick DK (2006) B1 and TRPV-1 receptor genes and their relationship to hyperalgesia following spinal cord injury. Spine 31:2778-2782
-
(2006)
Spine
, vol.31
, pp. 2778-2782
-
-
Dombourian, M.G.1
Turner, N.A.2
Gerovac, T.A.3
Vemuganti, R.4
Miranpuri, G.S.5
Türeyen, K.6
Satriotomo, I.7
Miletic, V.8
Resnick, D.K.9
-
51
-
-
0028113246
-
Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin
-
Dougherty PM, Palecek J, Palecková V, and Willis WD (1994) Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin. J Neurophysiol 72:1464-1475
-
(1994)
J Neurophysiol
, vol.72
, pp. 1464-1475
-
-
Dougherty, P.M.1
Palecek, J.2
Palecková, V.3
Willis, W.D.4
-
52
-
-
0026552580
-
Enhanced responses of spinothalamic tract neurons to excitatory amino acids accompany capsaicin-induced sensitization in the monkey
-
Dougherty PM and Willis WD (1992) Enhanced responses of spinothalamic tract neurons to excitatory amino acids accompany capsaicin-induced sensitization in the monkey. J Neurosci 12:883-894
-
(1992)
J Neurosci
, vol.12
, pp. 883-894
-
-
Dougherty, P.M.1
Willis, W.D.2
-
53
-
-
0037107184
-
Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius
-
Doyle MW, Bailey TW, Jin YH, and Andresen MC (2002) Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius. J Neurosci 22:8222-8229
-
(2002)
J Neurosci
, vol.22
, pp. 8222-8229
-
-
Doyle, M.W.1
Bailey, T.W.2
Jin, Y.H.3
Andresen, M.C.4
-
54
-
-
0142240092
-
Multi-modal induction and assessment of allodynia and hyperalgesia in the human oesophagus
-
Drewes AM, Schipper KP, Dimcevski G, Petersen P, Andersen OK, Gregersen H, and Arendt-Nielsen L (2003a) Multi-modal induction and assessment of allodynia and hyperalgesia in the human oesophagus. Eur J Pain 7:539-549
-
(2003)
Eur J Pain
, vol.7
, pp. 539-549
-
-
Drewes, A.M.1
Schipper, K.P.2
Dimcevski, G.3
Petersen, P.4
Andersen, O.K.5
Gregersen, H.6
Arendt-Nielsen, L.7
-
55
-
-
0038499609
-
Gut pain and hyperalgesia induced by capsaicin: A human experimental model
-
Drewes AM, Schipper KP, Dimcevski G, Petersen P, Gregersen H, Funch-Jensen P, and Arendt-Nielsen L (2003b) Gut pain and hyperalgesia induced by capsaicin: a human experimental model. Pain 104:333-341
-
(2003)
Pain
, vol.104
, pp. 333-341
-
-
Drewes, A.M.1
Schipper, K.P.2
Dimcevski, G.3
Petersen, P.4
Gregersen, H.5
Funch-Jensen, P.6
Arendt-Nielsen, L.7
-
56
-
-
0037180985
-
Capsaicinoids in vegetative organs of Capsicum annuum L. in relation to fruiting
-
Estrada B, Bernal MA, Díaz J, Pomar F, and Merino F (2002) Capsaicinoids in vegetative organs of Capsicum annuum L. in relation to fruiting. J Agric Food Chem 50:1188-1191
-
(2002)
J Agric Food Chem
, vol.50
, pp. 1188-1191
-
-
Estrada, B.1
Bernal, M.A.2
Díaz, J.3
Pomar, F.4
Merino, F.5
-
57
-
-
14544301098
-
Calcium/calmodulin dependent protein kinase II regulates the phosphorylation of cyclic AMP-responsive elementbinding protein of spinal cord in rats following noxious stimulation
-
Fang L, Wu J, Zhang X, Lin Q, and Willis WD (2005) Calcium/calmodulin dependent protein kinase II regulates the phosphorylation of cyclic AMP-responsive elementbinding protein of spinal cord in rats following noxious stimulation. Neurosci Lett 374:1-4
-
(2005)
Neurosci Lett
, vol.374
, pp. 1-4
-
-
Fang, L.1
Wu, J.2
Zhang, X.3
Lin, Q.4
Willis, W.D.5
-
58
-
-
84859901805
-
The functions of TRPA1 and TRPV1: Moving away from sensory nerves
-
Fernandes ES, Fernandes MA, and Keeble JE (2012) The functions of TRPA1 and TRPV1: moving away from sensory nerves. Br J Pharmacol 166:510-521
-
(2012)
Br J Pharmacol
, vol.166
, pp. 510-521
-
-
Fernandes, E.S.1
Fernandes, M.A.2
Keeble, J.E.3
-
59
-
-
23944442240
-
Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis
-
Fernihough J, Gentry C, Bevan S, and Winter J (2005) Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis. Neurosci Lett 388:75-80
-
(2005)
Neurosci Lett
, vol.388
, pp. 75-80
-
-
Fernihough, J.1
Gentry, C.2
Bevan, S.3
Winter, J.4
-
60
-
-
34047266824
-
Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse
-
Ferrini F, Salio C, Vergnano AM, and Merighi A (2007) Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse. Pain 129:195-209
-
(2007)
Pain
, vol.129
, pp. 195-209
-
-
Ferrini, F.1
Salio, C.2
Vergnano, A.M.3
Merighi, A.4
-
61
-
-
0024124461
-
Cough and bronchoconstriction mediated by capsaicin-sensitive sensory neurons in the guinea-pig
-
Forsberg K, Karlsson JA, Theodorsson E, Lundberg JM, and Persson CG (1988) Cough and bronchoconstriction mediated by capsaicin-sensitive sensory neurons in the guinea-pig. Pulm Pharmacol 1:33-39
-
(1988)
Pulm Pharmacol
, vol.1
, pp. 33-39
-
-
Forsberg, K.1
Karlsson, J.A.2
Theodorsson, E.3
Lundberg, J.M.4
Persson, C.G.5
-
62
-
-
41749117999
-
Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans
-
Gavva NR, Treanor JJ, Garami A, Fang L, Surapaneni S, Akrami A, Alvarez F, Bak A, Darling M, Gore A, et al. (2008) Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans. Pain 136:202-210
-
(2008)
Pain
, vol.136
, pp. 202-210
-
-
Gavva, N.R.1
Treanor, J.J.2
Garami, A.3
Fang, L.4
Surapaneni, S.5
Akrami, A.6
Alvarez, F.7
Bak, A.8
Darling, M.9
Gore, A.10
-
63
-
-
27644442319
-
A human experimental capsaicin model for trigeminal sensitization. Gender-specific differences
-
Gazerani P, Andersen OK, and Arendt-Nielsen L (2005) A human experimental capsaicin model for trigeminal sensitization. Gender-specific differences. Pain 118:155-163
-
(2005)
Pain
, vol.118
, pp. 155-163
-
-
Gazerani, P.1
Andersen, O.K.2
Arendt-Nielsen, L.3
-
64
-
-
33745000127
-
The effects of Botulinum Toxin type A on capsaicin-evoked pain, flare, and secondary hyperalgesia in an experimental human model of trigeminal sensitization
-
Gazerani P, Staahl C, Drewes AM, and Arendt-Nielsen L (2006) The effects of Botulinum Toxin type A on capsaicin-evoked pain, flare, and secondary hyperalgesia in an experimental human model of trigeminal sensitization. Pain 122:315-325
-
(2006)
Pain
, vol.122
, pp. 315-325
-
-
Gazerani, P.1
Staahl, C.2
Drewes, A.M.3
Arendt-Nielsen, L.4
-
65
-
-
0031778305
-
Effect of capsaicin-containing red pepper sauce suspension on upper gastrointestinal motility in healthy volunteers
-
Gonzalez R, Dunkel R, Koletzko B, Schusdziarra V, and Allescher HD (1998) Effect of capsaicin-containing red pepper sauce suspension on upper gastrointestinal motility in healthy volunteers. Dig Dis Sci 43:1165-1171
-
(1998)
Dig Dis Sci
, vol.43
, pp. 1165-1171
-
-
Gonzalez, R.1
Dunkel, R.2
Koletzko, B.3
Schusdziarra, V.4
Allescher, H.D.5
-
66
-
-
79960755348
-
Structural and functional regulation of growth cone, filopodia and synaptic sites by TRPV1
-
Goswami C (2010) Structural and functional regulation of growth cone, filopodia and synaptic sites by TRPV1. Commun Integr Biol 3:614-618
-
(2010)
Commun Integr Biol
, vol.3
, pp. 614-618
-
-
Goswami, C.1
-
68
-
-
33644842683
-
Rapid disassembly of dynamic microtubules upon activation of the capsaicin receptor TRPV1
-
Goswami C, Dreger M, Otto H, Schwappach B, and Hucho F (2006) Rapid disassembly of dynamic microtubules upon activation of the capsaicin receptor TRPV1. J Neurochem 96:254-266
-
(2006)
J Neurochem
, vol.96
, pp. 254-266
-
-
Goswami, C.1
Dreger, M.2
Otto, H.3
Schwappach, B.4
Hucho, F.5
-
69
-
-
79961153567
-
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
-
Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, and Julius D (2011) Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature 476:88-91
-
(2011)
Nature
, vol.476
, pp. 88-91
-
-
Gracheva, E.O.1
Cordero-Morales, J.F.2
González-Carcacía, J.A.3
Ingolia, N.T.4
Manno, C.5
Aranguren, C.I.6
Weissman, J.S.7
Julius, D.8
-
70
-
-
0035103813
-
The peripheral apparatus of muscle pain: Evidence from animal and human studies
-
Graven-Nielsen T and Mense S (2001) The peripheral apparatus of muscle pain: evidence from animal and human studies. Clin J Pain 17:2-10
-
(2001)
Clin J Pain
, vol.17
, pp. 2-10
-
-
Graven-Nielsen, T.1
Mense, S.2
-
71
-
-
0031049820
-
Quantification of local and referred muscle pain in humans after sequential i.m. injections of hypertonic saline
-
Graven-Nielsen T, Arendt-Nielsen L, Svensson P, and Jensen TS (1997) Quantification of local and referred muscle pain in humans after sequential i.m. injections of hypertonic saline. Pain 69:111-117
-
(1997)
Pain
, vol.69
, pp. 111-117
-
-
Graven-Nielsen, T.1
Arendt-Nielsen, L.2
Svensson, P.3
Jensen, T.S.4
-
72
-
-
80053195723
-
Biomarkers for visceral hypersensitivity identified by classification of electroencephalographic frequency alterations
-
Graversen C, Brock C, Drewes AM, and Farina D (2011) Biomarkers for visceral hypersensitivity identified by classification of electroencephalographic frequency alterations. J Neural Eng 8:056014
-
(2011)
J Neural Eng
, vol.8
, pp. 056014
-
-
Graversen, C.1
Brock, C.2
Drewes, A.M.3
Farina, D.4
-
73
-
-
0032967640
-
Immunocytochemical localization of the vanilloid receptor 1 (VR1): Relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites
-
Guo A, Vulchanova L, Wang J, Li X, and Elde R (1999) Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci 11:946-958
-
(1999)
Eur J Neurosci
, vol.11
, pp. 946-958
-
-
Guo, A.1
Vulchanova, L.2
Wang, J.3
Li, X.4
Elde, R.5
-
74
-
-
33746455735
-
Effect of repeated capsaicin ingestion on intestinal chemosensation and mechanosensation
-
Hammer J (2006) Effect of repeated capsaicin ingestion on intestinal chemosensation and mechanosensation. Aliment Pharmacol Ther 24:679-686
-
(2006)
Aliment Pharmacol Ther
, vol.24
, pp. 679-686
-
-
Hammer, J.1
-
75
-
-
0031853982
-
Intraluminal capsaicin does not affect fluid and electrolyte absorption in the human jejunum but does cause pain
-
Hammer J, Hammer HF, Eherer AJ, Petritsch W, Holzer P, and Krejs GJ (1998) Intraluminal capsaicin does not affect fluid and electrolyte absorption in the human jejunum but does cause pain. Gut 43:252-255
-
(1998)
Gut
, vol.43
, pp. 252-255
-
-
Hammer, J.1
Hammer, H.F.2
Eherer, A.J.3
Petritsch, W.4
Holzer, P.5
Krejs, G.J.6
-
76
-
-
33947503996
-
Characterization of sensations induced by capsaicin in the upper gastrointestinal tract
-
Hammer J and Vogelsang H (2007) Characterization of sensations induced by capsaicin in the upper gastrointestinal tract. Neurogastroenterol Motil 19:279-287
-
(2007)
Neurogastroenterol Motil
, vol.19
, pp. 279-287
-
-
Hammer, J.1
Vogelsang, H.2
-
77
-
-
56949104715
-
Capsaicin: A review of its pharmacology and clinical applications
-
Hayman M and Kam P (2008) Capsaicin: a review of its pharmacology and clinical applications. Curr Anaesth Crit Care 19:338-343
-
(2008)
Curr Anaesth Crit Care
, vol.19
, pp. 338-343
-
-
Hayman, M.1
Kam, P.2
-
78
-
-
0034899135
-
Sensitivity of vagal afferent endings to chemical irritants in the rat lung
-
Ho CY, Gu Q, Lin YS, and Lee LY (2001) Sensitivity of vagal afferent endings to chemical irritants in the rat lung. Respir Physiol 127:113-124
-
(2001)
Respir Physiol
, vol.127
, pp. 113-124
-
-
Ho, C.Y.1
Gu, Q.2
Lin, Y.S.3
Lee, L.Y.4
-
79
-
-
37849037118
-
The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level
-
Horvath G, Kekesi G, Nagy E, and Benedek G (2008) The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level. Pain 134:277-284
-
(2008)
Pain
, vol.134
, pp. 277-284
-
-
Horvath, G.1
Kekesi, G.2
Nagy, E.3
Benedek, G.4
-
80
-
-
33747235382
-
Inflammatory pain: The cellular basis of heat hyperalgesia
-
Huang J, Zhang X, and McNaughton PA (2006) Inflammatory pain: the cellular basis of heat hyperalgesia. Curr Neuropharmacol 4:197-206
-
(2006)
Curr Neuropharmacol
, vol.4
, pp. 197-206
-
-
Huang, J.1
Zhang, X.2
McNaughton, P.A.3
-
81
-
-
0037062411
-
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
-
Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, Tognetto M, Petros TJ, Krey JF, Chu CJ, et al. (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA 99:8400-8405
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8400-8405
-
-
Huang, S.M.1
Bisogno, T.2
Trevisani, M.3
Al-Hayani, A.4
de Petrocellis, L.5
Fezza, F.6
Tognetto, M.7
Petros, T.J.8
Krey, J.F.9
Chu, C.J.10
-
82
-
-
0036710218
-
Assessment of the reproducibility of intradermal administration of capsaicin as a model for inducing human pain
-
Hughes A, Macleod A, Growcott J, and Thomas I (2002) Assessment of the reproducibility of intradermal administration of capsaicin as a model for inducing human pain. Pain 99:323-331
-
(2002)
Pain
, vol.99
, pp. 323-331
-
-
Hughes, A.1
Macleod, A.2
Growcott, J.3
Thomas, I.4
-
83
-
-
0004906771
-
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
-
Hwang SW, Cho H, Kwak J, Lee SY, Kang CJ, Jung J, Cho S, Min KH, Suh YG, Kim D, et al. (2000) Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci USA 97:6155-6160
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6155-6160
-
-
Hwang, S.W.1
Cho, H.2
Kwak, J.3
Lee, S.Y.4
Kang, C.J.5
Jung, J.6
Cho, S.7
Min, K.H.8
Suh, Y.G.9
Kim, D.10
-
84
-
-
29144489340
-
Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans
-
Iannetti GD, Zambreanu L, Wise RG, Buchanan TJ, Huggins JP, Smart TS, Vennart W, and Tracey I (2005) Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans. Proc Natl Acad Sci USA 102:18195-18200
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18195-18200
-
-
Iannetti, G.D.1
Zambreanu, L.2
Wise, R.G.3
Buchanan, T.J.4
Huggins, J.P.5
Smart, T.S.6
Vennart, W.7
Tracey, I.8
-
85
-
-
84855830828
-
NGX-4010, a capsaicin 8% dermal patch, administered alone or in combination with systemic neuropathic pain medications, reduces pain in patients with postherpetic neuralgia
-
Irving G, Backonja M, Rauck R, Webster LR, Tobias JK, and Vanhove GF (2012) NGX-4010, a capsaicin 8% dermal patch, administered alone or in combination with systemic neuropathic pain medications, reduces pain in patients with postherpetic neuralgia. Clin J Pain 28:101-107
-
(2012)
Clin J Pain
, vol.28
, pp. 101-107
-
-
Irving, G.1
Backonja, M.2
Rauck, R.3
Webster, L.R.4
Tobias, J.K.5
Vanhove, G.F.6
-
86
-
-
0017720392
-
Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones
-
Jancsó G, Kiraly E, and Jancsó-Gábor A (1977) Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature 270:741-743
-
(1977)
Nature
, vol.270
, pp. 741-743
-
-
Jancsó, G.1
Kiraly, E.2
Jancsó-Gábor, A.3
-
87
-
-
63449092254
-
Explicit episodic memory for sensory-discriminative components of capsaicin-induced pain: Immediate and delayed ratings
-
Jantsch HH, Gawlitza M, Geber C, Baumgärtner U, Krämer HH, Magerl W, Treede RD, and Birklein F (2009) Explicit episodic memory for sensory-discriminative components of capsaicin-induced pain: immediate and delayed ratings. Pain 143: 97-105
-
(2009)
Pain
, vol.143
, pp. 97-105
-
-
Jantsch, H.H.1
Gawlitza, M.2
Geber, C.3
Baumgärtner, U.4
Krämer, H.H.5
Magerl, W.6
Treede, R.D.7
Birklein, F.8
-
89
-
-
0037179755
-
Schmoll R, and Woolf CJ (2002) p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
-
Ji RR, Samad TA, Jin SX, Schmoll R, and Woolf CJ (2002) p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36:57-68
-
Neuron
, vol.36
, pp. 57-68
-
-
Ji, R.R.1
Samad, T.A.2
Jin, S.X.3
-
90
-
-
33847785854
-
Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin
-
Johnson W Jr (2007) Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin. Int J Toxicol 26 (Suppl 1):3-106
-
(2007)
Int J Toxicol
, vol.26
, Issue.SUPPL. 1
, pp. 3-106
-
-
Johnson Jr., W.1
-
92
-
-
0036183319
-
Molecular basis for species-specific sensitivity to "hot" chili peppers
-
Jordt SE and Julius D (2002) Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108:421-430
-
(2002)
Cell
, vol.108
, pp. 421-430
-
-
Jordt, S.E.1
Julius, D.2
-
93
-
-
0034608878
-
Acid potentiation of the capsaicin receptor determined by a key extracellular site
-
Jordt SE, Tominaga M, and Julius D (2000) Acid potentiation of the capsaicin receptor determined by a key extracellular site. Proc Natl Acad Sci USA 97:8134-8139
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8134-8139
-
-
Jordt, S.E.1
Tominaga, M.2
Julius, D.3
-
95
-
-
34447331071
-
Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia
-
Kanai Y, Hara T, Imai A, and Sakakibara A (2007) Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia. J Pharm Pharmacol 59:733-738
-
(2007)
J Pharm Pharmacol
, vol.59
, pp. 733-738
-
-
Kanai, Y.1
Hara, T.2
Imai, A.3
Sakakibara, A.4
-
97
-
-
0021351360
-
Gastrointestinal absorption and metabolism of capsaicin and dihydrocapsaicin in rats
-
Kawada T, Suzuki T, Takahashi M, and Iwai K (1984) Gastrointestinal absorption and metabolism of capsaicin and dihydrocapsaicin in rats. Toxicol Appl Pharmacol 72:449-456
-
(1984)
Toxicol Appl Pharmacol
, vol.72
, pp. 449-456
-
-
Kawada, T.1
Suzuki, T.2
Takahashi, M.3
Iwai, K.4
-
98
-
-
46549084522
-
Contribution of transient receptor potential vanilloid subfamily 1 to endothelin-1- induced thermal hyperalgesia
-
Kawamata T, Ji W, Yamamoto J, Niiyama Y, Furuse S, and Namiki A (2008) Contribution of transient receptor potential vanilloid subfamily 1 to endothelin-1- induced thermal hyperalgesia. Neuroscience 154:1067-1076
-
(2008)
Neuroscience
, vol.154
, pp. 1067-1076
-
-
Kawamata, T.1
Ji, W.2
Yamamoto, J.3
Niiyama, Y.4
Furuse, S.5
Namiki, A.6
-
99
-
-
0035958884
-
Analysis of the native quaternary structure of vanilloid receptor 1
-
Kedei N, Szabo T, Lile JD, Treanor JJ, Olah Z, Iadarola MJ, and Blumberg PM (2001) Analysis of the native quaternary structure of vanilloid receptor 1. J Biol Chem 276:28613-28619
-
(2001)
J Biol Chem
, vol.276
, pp. 28613-28619
-
-
Kedei, N.1
Szabo, T.2
Lile, J.D.3
Treanor, J.J.4
Olah, Z.5
Iadarola, M.J.6
Blumberg, P.M.7
-
100
-
-
77952743084
-
A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers
-
Kennedy WR, Vanhove GF, Lu SP, Tobias J, Bley KR, Walk D, Wendelschafer-Crabb G, Simone DA, and Selim MM (2010) A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers. J Pain 11:579-587
-
(2010)
J Pain
, vol.11
, pp. 579-587
-
-
Kennedy, W.R.1
Vanhove, G.F.2
Lu, S.P.3
Tobias, J.4
Bley, K.R.5
Walk, D.6
Wendelschafer-Crabb, G.7
Simone, D.A.8
Selim, M.M.9
-
101
-
-
0028340936
-
Different patterns of hyperalgesia induced by experimental inflammation in human skin
-
Kilo S, Schmelz M, Koltzenburg M, and Handwerker HO (1994) Different patterns of hyperalgesia induced by experimental inflammation in human skin. Brain 117: 385-396
-
(1994)
Brain
, vol.117
, pp. 385-396
-
-
Kilo, S.1
Schmelz, M.2
Koltzenburg, M.3
Handwerker, H.O.4
-
102
-
-
42949125051
-
Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1
-
Kim AY, Tang Z, Liu Q, Patel KN, Maag D, Geng Y, and Dong X (2008) Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell 133:475-485
-
(2008)
Cell
, vol.133
, pp. 475-485
-
-
Kim, A.Y.1
Tang, Z.2
Liu, Q.3
Patel, K.N.4
Maag, D.5
Geng, Y.6
Dong, X.7
-
103
-
-
2442420245
-
Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament
-
Kim H, Neubert JK, San Miguel A, Xu K, Krishnaraju RK, Iadarola MJ, Goldman D, and Dionne RA (2004) Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament. Pain 109:488-496
-
(2004)
Pain
, vol.109
, pp. 488-496
-
-
Kim, H.1
Neubert, J.K.2
San Miguel, A.3
Xu, K.4
Krishnaraju, R.K.5
Iadarola, M.J.6
Goldman, D.7
Dionne, R.A.8
-
104
-
-
70049102041
-
Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man
-
Kindt S, Vos R, Blondeau K, and Tack J (2009) Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man. Neurogastroenterol Motil 21:1032-e82
-
(2009)
Neurogastroenterol Motil
, vol.21
-
-
Kindt, S.1
Vos, R.2
Blondeau, K.3
Tack, J.4
-
105
-
-
80051781418
-
Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity
-
King T, Qu C, Okun A, Mercado R, Ren J, Brion T, Lai J, and Porreca F (2011) Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity. Pain 152:1997-2005
-
(2011)
Pain
, vol.152
, pp. 1997-2005
-
-
King, T.1
Qu, C.2
Okun, A.3
Mercado, R.4
Ren, J.5
Brion, T.6
Lai, J.7
Porreca, F.8
-
106
-
-
35748972058
-
Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia
-
Klein T, Magerl W, Hanschmann A, Althaus M, and Treede RD (2008) Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia. Eur J Pain 12:17-29
-
(2008)
Eur J Pain
, vol.12
, pp. 17-29
-
-
Klein, T.1
Magerl, W.2
Hanschmann, A.3
Althaus, M.4
Treede, R.D.5
-
107
-
-
0026749526
-
Dynamic and static components of mechanical hyperalgesia in human hairy skin
-
Koltzenburg M, Lundberg LE, and Torebjörk HE (1992) Dynamic and static components of mechanical hyperalgesia in human hairy skin. Pain 51:207-219
-
(1992)
Pain
, vol.51
, pp. 207-219
-
-
Koltzenburg, M.1
Lundberg, L.E.2
Torebjörk, H.E.3
-
108
-
-
0030956114
-
The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons
-
Koplas PA, Rosenberg RL, and Oxford GS (1997) The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons. J Neurosci 17:3525-3537
-
(1997)
J Neurosci
, vol.17
, pp. 3525-3537
-
-
Koplas, P.A.1
Rosenberg, R.L.2
Oxford, G.S.3
-
109
-
-
79954617292
-
Randomised clinical trial: The efficacy of a transient receptor potential vanilloid 1 antagonist AZD1386 in human oesophageal pain
-
Krarup AL, Ny L, Astrand M, Bajor A, Hvid-Jensen F, Hansen MB, Simrén M, Funch-Jensen P, and Drewes AM (2011) Randomised clinical trial: the efficacy of a transient receptor potential vanilloid 1 antagonist AZD1386 in human oesophageal pain. Aliment Pharmacol Ther 33:1113-1122
-
(2011)
Aliment Pharmacol Ther
, vol.33
, pp. 1113-1122
-
-
Krarup, A.L.1
Ny, L.2
Astrand, M.3
Bajor, A.4
Hvid-Jensen, F.5
Hansen, M.B.6
Simrén, M.7
Funch-Jensen, P.8
Drewes, A.M.9
-
110
-
-
0026508601
-
Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin
-
LaMotte RH, Lundberg LE, and Torebjörk HE (1992) Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin. J Physiol 448:749-764
-
(1992)
J Physiol
, vol.448
, pp. 749-764
-
-
Lamotte, R.H.1
Lundberg, L.E.2
Torebjörk, H.E.3
-
111
-
-
0025868408
-
Neurogenic hyperalgesia: Psychophysical studies of underlying mechanisms
-
LaMotte RH, Shain CN, Simone DA, and Tsai EF (1991) Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. J Neurophysiol 66:190-211
-
(1991)
J Neurophysiol
, vol.66
, pp. 190-211
-
-
Lamotte, R.H.1
Shain, C.N.2
Simone, D.A.3
Tsai, E.F.4
-
112
-
-
84856470083
-
The role of TRPV1 channel in aged human skin
-
Lee YM, Kang SM, and Chung JH (2012) The role of TRPV1 channel in aged human skin. J Dermatol Sci 65:81-85
-
(2012)
J Dermatol Sci
, vol.65
, pp. 81-85
-
-
Lee, Y.M.1
Kang, S.M.2
Chung, J.H.3
-
113
-
-
36249003457
-
The role of reactive oxygen species in capsaicin-induced mechanical hyperalgesia and in the activities of dorsal horn neurons
-
Lee I, Kim HK, Kim JH, Chung K, and Chung JM (2007) The role of reactive oxygen species in capsaicin-induced mechanical hyperalgesia and in the activities of dorsal horn neurons. Pain 133:9-17
-
(2007)
Pain
, vol.133
, pp. 9-17
-
-
Lee, I.1
Kim, H.K.2
Kim, J.H.3
Chung, K.4
Chung, J.M.5
-
114
-
-
1542359489
-
Effects of capsaicin on the sensorimotor function of the proximal stomach in humans
-
Lee KJ, Vos R, and Tack J (2004) Effects of capsaicin on the sensorimotor function of the proximal stomach in humans. Aliment Pharmacol Ther 19:415-425
-
(2004)
Aliment Pharmacol Ther
, vol.19
, pp. 415-425
-
-
Lee, K.J.1
Vos, R.2
Tack, J.3
-
115
-
-
58149233771
-
Identifying brain activity specifically related to the maintenance and perceptual consequence of central sensitization in humans
-
Lee MC, Zambreanu L, Menon DK, and Tracey I (2008) Identifying brain activity specifically related to the maintenance and perceptual consequence of central sensitization in humans. J Neurosci 28:11642-11649
-
(2008)
J Neurosci
, vol.28
, pp. 11642-11649
-
-
Lee, M.C.1
Zambreanu, L.2
Menon, D.K.3
Tracey, I.4
-
116
-
-
65249094164
-
Increased expression of TRPV1 channel in intrinsically aged and photoaged human skin in vivo
-
Lee YM, Kim YK, and Chung JH (2009) Increased expression of TRPV1 channel in intrinsically aged and photoaged human skin in vivo. Exp Dermatol 18:431-436
-
(2009)
Exp Dermatol
, vol.18
, pp. 431-436
-
-
Lee, Y.M.1
Kim, Y.K.2
Chung, J.H.3
-
117
-
-
33847772791
-
In vitro capsaicin metabolism in the rat, mouse and hamster
-
Leelahuta Y, Glinsukon T, and Wangpanish W (1983) In vitro capsaicin metabolism in the rat, mouse and hamster. Toxicon 21 (Suppl 3):245-248
-
(1983)
Toxicon
, vol.21
, Issue.SUPPL. 3
, pp. 245-248
-
-
Leelahuta, Y.1
Glinsukon, T.2
Wangpanish, W.3
-
118
-
-
56349133869
-
Sensitization of primary afferent nociceptors induced by intradermal capsaicin involves the peripheral release of calcitonin gene-related peptide driven by dorsal root reflexes
-
Li D, Ren Y, Xu X, Zou X, Fang L, and Lin Q (2008) Sensitization of primary afferent nociceptors induced by intradermal capsaicin involves the peripheral release of calcitonin gene-related peptide driven by dorsal root reflexes. J Pain 9:1155-1168
-
(2008)
J Pain
, vol.9
, pp. 1155-1168
-
-
Li, D.1
Ren, Y.2
Xu, X.3
Zou, X.4
Fang, L.5
Lin, Q.6
-
119
-
-
24144490391
-
Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex
-
Liapi A and Wood JN (2005) Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. Eur J Neurosci 22:825-834
-
(2005)
Eur J Neurosci
, vol.22
, pp. 825-834
-
-
Liapi, A.1
Wood, J.N.2
-
120
-
-
0032127027
-
The human capsaicin model of allodynia and hyperalgesia: Sources of variability and methods for reduction
-
Liu M, Max MB, Robinovitz E, Gracely RH, and Bennett GJ (1998) The human capsaicin model of allodynia and hyperalgesia: sources of variability and methods for reduction. J Pain Symptom Manage 16:10-20
-
(1998)
J Pain Symptom Manage
, vol.16
, pp. 10-20
-
-
Liu, M.1
Max, M.B.2
Robinovitz, E.3
Gracely, R.H.4
Bennett, G.J.5
-
121
-
-
0028008659
-
Chili pepper consumption and gastric cancer in Mexico: A case-control study
-
López-Carrillo L, Hernández Avila M, and Dubrow R (1994) Chili pepper consumption and gastric cancer in Mexico: a case-control study. Am J Epidemiol 139:263-271
-
(1994)
Am J Epidemiol
, vol.139
, pp. 263-271
-
-
López-Carrillo, L.1
Hernández, A.M.2
Dubrow, R.3
-
122
-
-
15744394354
-
TRPV1b, a functional human vanilloid receptor splice variant
-
Lu G, Henderson D, Liu L, Reinhart PH, and Simon SA (2005) TRPV1b, a functional human vanilloid receptor splice variant. Mol Pharmacol 67:1119-1127
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1119-1127
-
-
Lu, G.1
Henderson, D.2
Liu, L.3
Reinhart, P.H.4
Simon, S.A.5
-
123
-
-
0020463846
-
Bronchial smooth muscle contraction induced by stimulation of capsaicin-sensitive sensory neurons
-
Lundberg JM and Saria A (1982) Bronchial smooth muscle contraction induced by stimulation of capsaicin-sensitive sensory neurons. Acta Physiol Scand 116:473-476
-
(1982)
Acta Physiol Scand
, vol.116
, pp. 473-476
-
-
Lundberg, J.M.1
Saria, A.2
-
124
-
-
0031952973
-
Secondary hyperalgesia and perceptual wind-up following intradermal injection of capsaicin in humans
-
Magerl W, Wilk SH, and Treede RD (1998) Secondary hyperalgesia and perceptual wind-up following intradermal injection of capsaicin in humans. Pain 74:257-268
-
(1998)
Pain
, vol.74
, pp. 257-268
-
-
Magerl, W.1
Wilk, S.H.2
Treede, R.D.3
-
125
-
-
0023833519
-
The sensory-efferent function of capsaicin-sensitive sensory neurons
-
Maggi CA and Meli A (1988) The sensory-efferent function of capsaicin-sensitive sensory neurons. Gen Pharmacol 19:1-43
-
(1988)
Gen Pharmacol
, vol.19
, pp. 1-43
-
-
Maggi, C.A.1
Meli, A.2
-
126
-
-
1942467891
-
Systematic review of topical capsaicin for the treatment of chronic pain
-
Mason L, Moore RA, Derry S, Edwards JE, and McQuay HJ (2004) Systematic review of topical capsaicin for the treatment of chronic pain. BMJ 328:991
-
(2004)
BMJ
, vol.328
, pp. 991
-
-
Mason, L.1
Moore, R.A.2
Derry, S.3
Edwards, J.E.4
McQuay, H.J.5
-
127
-
-
33846230027
-
TRPV1 is a novel target for omega-3 polyunsaturated fatty acids
-
Matta JA, Miyares RL, and Ahern GP (2007) TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. J Physiol 578:397-411
-
(2007)
J Physiol
, vol.578
, pp. 397-411
-
-
Matta, J.A.1
Miyares, R.L.2
Ahern, G.P.3
-
128
-
-
4444357719
-
Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human oesophagus
-
Matthews PJ, Aziz Q, Facer P, Davis JB, Thompson DG, and Anand P (2004) Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human oesophagus. Eur J Gastroenterol Hepatol 16:897-902
-
(2004)
Eur J Gastroenterol Hepatol
, vol.16
, pp. 897-902
-
-
Matthews, P.J.1
Aziz, Q.2
Facer, P.3
Davis, J.B.4
Thompson, D.G.5
Anand, P.6
-
129
-
-
0142090230
-
Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM
-
McGaraughty S, Chu KL, Bitner RS, Martino B, El Kouhen R, Han P, Nikkel AL, Burgard EC, Faltynek CR, and Jarvis MF (2003) Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. J Neurophysiol 90:2702-2710
-
(2003)
J Neurophysiol
, vol.90
, pp. 2702-2710
-
-
McGaraughty, S.1
Chu, K.L.2
Bitner, R.S.3
Martino, B.4
El Kouhen, R.5
Han, P.6
Nikkel, A.L.7
Burgard, E.C.8
Faltynek, C.R.9
Jarvis, M.F.10
-
130
-
-
0026093493
-
The consequences of long-term topical capsaicin application in the rat
-
McMahon SB, Lewin G, and Bloom SR (1991) The consequences of long-term topical capsaicin application in the rat. Pain 44:301-310
-
(1991)
Pain
, vol.44
, pp. 301-310
-
-
McMahon, S.B.1
Lewin, G.2
Bloom, S.R.3
-
132
-
-
33646043767
-
Increasingly irritable and close to tears: TRPA1 in inflammatory pain
-
McMahon SB and Wood JN (2006) Increasingly irritable and close to tears: TRPA1 in inflammatory pain. Cell 124:1123-1125
-
(2006)
Cell
, vol.124
, pp. 1123-1125
-
-
McMahon, S.B.1
Wood, J.N.2
-
133
-
-
77957771961
-
Naga chilli: A potential source of capsaicinoids with broad-spectrum ethnopharmacological applications
-
Meghvansi MK, Siddiqui S, Khan MH, Gupta VK, Vairale MG, Gogoi HK, and Singh L (2010) Naga chilli: a potential source of capsaicinoids with broad-spectrum ethnopharmacological applications. J Ethnopharmacol 132:1-14
-
(2010)
J Ethnopharmacol
, vol.132
, pp. 1-14
-
-
Meghvansi, M.K.1
Siddiqui, S.2
Khan, M.H.3
Gupta, V.K.4
Vairale, M.G.5
Gogoi, H.K.6
Singh, L.7
-
134
-
-
0036277865
-
Descending control of pain
-
Millan MJ (2002) Descending control of pain. Prog Neurobiol 66:355-474
-
(2002)
Prog Neurobiol
, vol.66
, pp. 355-474
-
-
Millan, M.J.1
-
135
-
-
79551581638
-
TRPV1-lineage neurons are required for thermal sensation
-
Mishra SK, Tisel SM, Orestes P, Bhangoo SK, and Hoon MA (2011) TRPV1-lineage neurons are required for thermal sensation. EMBO J 30:582-593
-
(2011)
EMBO J
, vol.30
, pp. 582-593
-
-
Mishra, S.K.1
Tisel, S.M.2
Orestes, P.3
Bhangoo, S.K.4
Hoon, M.A.5
-
136
-
-
16244375523
-
Expression and characterization of the intracellular vanilloid receptor (TRPV1) in bronchi from patients with chronic cough
-
Mitchell JE, Campbell AP, New NE, Sadofsky LR, Kastelik JA, Mulrennan SA, Compton SJ, and Morice AH (2005) Expression and characterization of the intracellular vanilloid receptor (TRPV1) in bronchi from patients with chronic cough. Exp Lung Res 31:295-306
-
(2005)
Exp Lung Res
, vol.31
, pp. 295-306
-
-
Mitchell, J.E.1
Campbell, A.P.2
New, N.E.3
Sadofsky, L.R.4
Kastelik, J.A.5
Mulrennan, S.A.6
Compton, S.J.7
Morice, A.H.8
-
137
-
-
77953114818
-
Human experimental pain models 3: Heat/capsaicin sensitization and intradermal capsaicin models
-
Modir JG and Wallace MS (2010) Human experimental pain models 3: heat/capsaicin sensitization and intradermal capsaicin models. Methods Mol Biol 617:169-174
-
(2010)
Methods Mol Biol
, vol.617
, pp. 169-174
-
-
Modir, J.G.1
Wallace, M.S.2
-
138
-
-
17144397173
-
2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase
-
2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase. J Biol Chem 280:13424-13432
-
(2005)
J Biol Chem
, vol.280
, pp. 13424-13432
-
-
Mohapatra, D.P.1
Nau, C.2
-
139
-
-
44949205447
-
Structure of TRPV1 channel revealed by electron cryomicroscopy
-
Moiseenkova-Bell VY, Stanciu LA, Serysheva II, Tobe BJ, and Wensel TG (2008) Structure of TRPV1 channel revealed by electron cryomicroscopy. Proc Natl Acad Sci USA 105:7451-7455
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7451-7455
-
-
Moiseenkova-Bell, V.Y.1
Stanciu, L.A.2
Serysheva, I.I.3
Tobe, B.J.4
Wensel, T.G.5
-
140
-
-
0020639498
-
Subchronic toxicity studies of capsaicin and capsicum in rats
-
Monsereenusorn Y (1983) Subchronic toxicity studies of capsaicin and capsicum in rats. Res Commun Chem Pathol Pharmacol 41:95-110
-
(1983)
Res Commun Chem Pathol Pharmacol
, vol.41
, pp. 95-110
-
-
Monsereenusorn, Y.1
-
141
-
-
33646769105
-
Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins
-
Moriyama T, Higashi T, Togashi K, Iida T, Segi E, Sugimoto Y, Tominaga T, Narumiya S, and Tominaga M (2005) Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins. Mol Pain 1:3
-
(2005)
Mol Pain
, vol.1
, pp. 3
-
-
Moriyama, T.1
Higashi, T.2
Togashi, K.3
Iida, T.4
Segi, E.5
Sugimoto, Y.6
Tominaga, T.7
Narumiya, S.8
Tominaga, M.9
-
142
-
-
33750976683
-
Capsaicin-evoked brain activation and central sensitization in anaesthetised rats: A functional magnetic resonance imaging study
-
Moylan Governo RJ, Morris PG, Prior MJ, Marsden CA, and Chapman V (2006) Capsaicin-evoked brain activation and central sensitization in anaesthetised rats: a functional magnetic resonance imaging study. Pain 126:35-45
-
(2006)
Pain
, vol.126
, pp. 35-45
-
-
Moylan, G.R.J.1
Morris, P.G.2
Prior, M.J.3
Marsden, C.A.4
Chapman, V.5
-
143
-
-
0032954612
-
Topical capsaicin in humans: Parallel loss of epidermal nerve fibers and pain sensation
-
Nolano M, Simone DA, Wendelschafer-Crabb G, Johnson T, Hazen E, and Kennedy WR (1999) Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation. Pain 81:135-145
-
(1999)
Pain
, vol.81
, pp. 135-145
-
-
Nolano, M.1
Simone, D.A.2
Wendelschafer-Crabb, G.3
Johnson, T.4
Hazen, E.5
Kennedy, W.R.6
-
144
-
-
68149094343
-
NGX-4010, a high-concentration capsaicin dermal patch for lasting relief of peripheral neuropathic pain
-
Noto C, Pappagallo M, and Szallasi A (2009) NGX-4010, a high-concentration capsaicin dermal patch for lasting relief of peripheral neuropathic pain. Curr Opin Investig Drugs 10:702-710
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 702-710
-
-
Noto, C.1
Pappagallo, M.2
Szallasi, A.3
-
145
-
-
0037134417
-
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues
-
Numazaki M, Tominaga T, Toyooka H, and Tominaga M (2002) Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues. J Biol Chem 277:13375-13378
-
(2002)
J Biol Chem
, vol.277
, pp. 13375-13378
-
-
Numazaki, M.1
Tominaga, T.2
Toyooka, H.3
Tominaga, M.4
-
146
-
-
78650977170
-
Transient inflammation-induced ongoing pain is driven by TRPV1 sensitive afferents
-
Okun A, DeFelice M, Eyde N, Ren J, Mercado R, King T, and Porreca F (2011) Transient inflammation-induced ongoing pain is driven by TRPV1 sensitive afferents. Mol Pain 7:4
-
(2011)
Mol Pain
, vol.7
, pp. 4
-
-
Okun, A.1
Defelice, M.2
Eyde, N.3
Ren, J.4
Mercado, R.5
King, T.6
Porreca, F.7
-
147
-
-
68349104327
-
Evoked human oesophageal hyperalgesia: A potential tool for analgesic evaluation?
-
Olesen AE, Staahl C, Brock C, Arendt-Nielsen L, and Drewes AM (2009) Evoked human oesophageal hyperalgesia: a potential tool for analgesic evaluation? Basic Clin Pharmacol Toxicol 105:126-136
-
(2009)
Basic Clin Pharmacol Toxicol
, vol.105
, pp. 126-136
-
-
Olesen, A.E.1
Staahl, C.2
Brock, C.3
Arendt-Nielsen, L.4
Drewes, A.M.5
-
148
-
-
77954505370
-
Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: A human translational study
-
Olesen AE, Staahl C, Arendt-Nielsen L, and Drewes AM (2010) Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study. Br J Clin Pharmacol 70:189-200
-
(2010)
Br J Clin Pharmacol
, vol.70
, pp. 189-200
-
-
Olesen, A.E.1
Staahl, C.2
Arendt-Nielsen, L.3
Drewes, A.M.4
-
149
-
-
0037192598
-
Interaction between vanilloid and glutamate receptors in the central modulation of nociception
-
Palazzo E, de Novellis V, Marabese I, Cuomo D, Rossi F, Berrino L, Rossi F, and Maione S (2002) Interaction between vanilloid and glutamate receptors in the central modulation of nociception. Eur J Pharmacol 439:69-75
-
(2002)
Eur J Pharmacol
, vol.439
, pp. 69-75
-
-
Palazzo, E.1
de Novellis, V.2
Marabese, I.3
Cuomo, D.4
Rossi, F.5
Berrino, L.6
Rossi, F.7
Maione, S.8
-
150
-
-
0028884581
-
Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects
-
Park KM, Max MB, Robinovitz E, Gracely RH, and Bennett GJ (1995) Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. Pain 63:163-172
-
(1995)
Pain
, vol.63
, pp. 163-172
-
-
Park, K.M.1
Max, M.B.2
Robinovitz, E.3
Gracely, R.H.4
Bennett, G.J.5
-
151
-
-
0009585811
-
Liquid chromatographic method for determining capsaicinoids in capsicums and their extractives: Collaborative study
-
Parrish M (1996) Liquid chromatographic method for determining capsaicinoids in capsicums and their extractives: collaborative study. J AOAC Int 79:738-745
-
(1996)
J AOAC Int
, vol.79
, pp. 738-745
-
-
Parrish, M.1
-
152
-
-
78651100594
-
Human visceral afferent recordings: Preliminary report
-
Peiris M, Bulmer DC, Baker MD, Boundouki G, Sinha S, Hobson A, Lee K, Aziz Q, and Knowles CH (2011) Human visceral afferent recordings: preliminary report. Gut 60:204-208
-
(2011)
Gut
, vol.60
, pp. 204-208
-
-
Peiris, M.1
Bulmer, D.C.2
Baker, M.D.3
Boundouki, G.4
Sinha, S.5
Hobson, A.6
Lee, K.7
Aziz, Q.8
Knowles, C.H.9
-
153
-
-
4644363137
-
Effects of vehicle on the uptake and elimination kinetics of capsaicinoids in human skin in vivo
-
Pershing LK, Reilly CA, Corlett JL, and Crouch DJ (2004) Effects of vehicle on the uptake and elimination kinetics of capsaicinoids in human skin in vivo. Toxicol Appl Pharmacol 200:73-81
-
(2004)
Toxicol Appl Pharmacol
, vol.200
, pp. 73-81
-
-
Pershing, L.K.1
Reilly, C.A.2
Corlett, J.L.3
Crouch, D.J.4
-
154
-
-
0033553322
-
A new human experimental pain model: The heat/capsaicin sensitization model
-
Petersen KL and Rowbotham MC (1999) A new human experimental pain model: the heat/capsaicin sensitization model. Neuroreport 10:1511-1516
-
(1999)
Neuroreport
, vol.10
, pp. 1511-1516
-
-
Petersen, K.L.1
Rowbotham, M.C.2
-
155
-
-
3142557927
-
The time course of epidermal nerve fibre regeneration: Studies in normal controls and in people with diabetes, with and without neuropathy
-
Polydefkis M, Hauer P, Sheth S, Sirdofsky M, Griffin JW, and McArthur JC (2004) The time course of epidermal nerve fibre regeneration: studies in normal controls and in people with diabetes, with and without neuropathy. Brain 127:1606-1615
-
(2004)
Brain
, vol.127
, pp. 1606-1615
-
-
Polydefkis, M.1
Hauer, P.2
Sheth, S.3
Sirdofsky, M.4
Griffin, J.W.5
McArthur, J.C.6
-
156
-
-
78649804666
-
PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150
-
Por ED, Samelson BK, Belugin S, Akopian AN, Scott JD, and Jeske NA (2010) PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150. Biochem J 432:549-556
-
(2010)
Biochem J
, vol.432
, pp. 549-556
-
-
Por, E.D.1
Samelson, B.K.2
Belugin, S.3
Akopian, A.N.4
Scott, J.D.5
Jeske, N.A.6
-
157
-
-
0034700494
-
Induction of vanilloid receptor channel activity by protein kinase C
-
Premkumar LS and Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408:985-990
-
(2000)
Nature
, vol.408
, pp. 985-990
-
-
Premkumar, L.S.1
Ahern, G.P.2
-
158
-
-
80052227817
-
Disease-related changes in TRPV1 expression and its implications for drug development
-
Premkumar LS and Bishnoi M (2011) Disease-related changes in TRPV1 expression and its implications for drug development. Curr Top Med Chem 11:2192-2209
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 2192-2209
-
-
Premkumar, L.S.1
Bishnoi, M.2
-
159
-
-
0037799198
-
A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity
-
Prescott ED and Julius D (2003) A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300:1284-1288
-
(2003)
Science
, vol.300
, pp. 1284-1288
-
-
Prescott, E.D.1
Julius, D.2
-
160
-
-
0030275897
-
Selective activation of A-delta and C nociceptive afferents by different parameters of nociceptive heat stimulation: A tool for analysis of central mechanisms of pain
-
Price DD (1996) Selective activation of A-delta and C nociceptive afferents by different parameters of nociceptive heat stimulation: a tool for analysis of central mechanisms of pain. Pain 68:1-3
-
(1996)
Pain
, vol.68
, pp. 1-3
-
-
Price, D.D.1
-
161
-
-
23744481023
-
Vasomotor response to cold stimulation in human capsaicin-induced hyperalgesic area
-
Pud D, Andersen OK, Arendt-Nielsen L, Eisenberg E, and Yarnitsky D (2005) Vasomotor response to cold stimulation in human capsaicin-induced hyperalgesic area. Exp Brain Res 164:334-340
-
(2005)
Exp Brain Res
, vol.164
, pp. 334-340
-
-
Pud, D.1
Andersen, O.K.2
Arendt-Nielsen, L.3
Eisenberg, E.4
Yarnitsky, D.5
-
162
-
-
33845412047
-
Metabolism of capsaicinoids by P450 enzymes: A review of recent findings on reaction mechanisms, bio-activation, and detoxification processes
-
Reilly CA and Yost GS (2006) Metabolism of capsaicinoids by P450 enzymes: a review of recent findings on reaction mechanisms, bio-activation, and detoxification processes. Drug Metab Rev 38:685-706
-
(2006)
Drug Metab Rev
, vol.38
, pp. 685-706
-
-
Reilly, C.A.1
Yost, G.S.2
-
164
-
-
79954584227
-
Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial
-
Rowbotham MC, Nothaft W, Duan WR, Wang Y, Faltynek C, McGaraughty S, Chu KL, and Svensson P (2011) Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain 152:1192-1200
-
(2011)
Pain
, vol.152
, pp. 1192-1200
-
-
Rowbotham, M.C.1
Nothaft, W.2
Duan, W.R.3
Wang, Y.4
Faltynek, C.5
McGaraughty, S.6
Chu, K.L.7
Svensson, P.8
-
165
-
-
33747195262
-
Local and descending circuits regulate long-term potentiation and zif268 expression in spinal neurons
-
Rygh LJ, Suzuki R, Rahman W, Wong Y, Vonsy JL, Sandhu H, Webber M, Hunt S, and Dickenson AH (2006) Local and descending circuits regulate long-term potentiation and zif268 expression in spinal neurons. Eur J Neurosci 24:761-772
-
(2006)
Eur J Neurosci
, vol.24
, pp. 761-772
-
-
Rygh, L.J.1
Suzuki, R.2
Rahman, W.3
Wong, Y.4
Vonsy, J.L.5
Sandhu, H.6
Webber, M.7
Hunt, S.8
Dickenson, A.H.9
-
166
-
-
0035940785
-
The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat
-
Sanchez JF, Krause JE, and Cortright DN (2001) The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat. Neuroscience 107:373-381
-
(2001)
Neuroscience
, vol.107
, pp. 373-381
-
-
Sanchez, J.F.1
Krause, J.E.2
Cortright, D.N.3
-
167
-
-
0019799194
-
Determination of capsaicin in tissues and separation of capsaicin analogues by high-performance liquid chromatography
-
Saria A, Lembeck F, and Skofitsch G (1981) Determination of capsaicin in tissues and separation of capsaicin analogues by high-performance liquid chromatography. J Chromatogr 208:41-46
-
(1981)
J Chromatogr
, vol.208
, pp. 41-46
-
-
Saria, A.1
Lembeck, F.2
Skofitsch, G.3
-
168
-
-
33845901493
-
Intradermal capsaicin causes dose-dependent pain, allodynia, and hyperalgesia in humans
-
Scanlon GC, Wallace MS, Ispirescu JS, and Schulteis G (2006) Intradermal capsaicin causes dose-dependent pain, allodynia, and hyperalgesia in humans. J Investig Med 54:238-244
-
(2006)
J Investig Med
, vol.54
, pp. 238-244
-
-
Scanlon, G.C.1
Wallace, M.S.2
Ispirescu, J.S.3
Schulteis, G.4
-
169
-
-
1842851537
-
Chemical nociception in the jejunum induced by capsaicin
-
Schmidt B, Hammer J, Holzer P, and Hammer HF (2004) Chemical nociception in the jejunum induced by capsaicin. Gut 53:1109-1116
-
(2004)
Gut
, vol.53
, pp. 1109-1116
-
-
Schmidt, B.1
Hammer, J.2
Holzer, P.3
Hammer, H.F.4
-
170
-
-
77954849932
-
Transient receptor potential channels in pain and inflammation: Therapeutic opportunities
-
Schumacher MA (2010) Transient receptor potential channels in pain and inflammation: therapeutic opportunities. Pain Pract 10:185-200
-
(2010)
Pain Pract
, vol.10
, pp. 185-200
-
-
Schumacher, M.A.1
-
171
-
-
33947134894
-
Capsaicin induces the production of IL-6 in human upper respiratory epithelial cells
-
Seki N, Shirasaki H, Kikuchi M, and Himi T (2007) Capsaicin induces the production of IL-6 in human upper respiratory epithelial cells. Life Sci 80:1592-1597
-
(2007)
Life Sci
, vol.80
, pp. 1592-1597
-
-
Seki, N.1
Shirasaki, H.2
Kikuchi, M.3
Himi, T.4
-
173
-
-
0024351831
-
Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin
-
Simone DA, Baumann TK, and LaMotte RH (1989) Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain 38:99-107
-
(1989)
Pain
, vol.38
, pp. 99-107
-
-
Simone, D.A.1
Baumann, T.K.2
Lamotte, R.H.3
-
175
-
-
0032211125
-
Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: Correlation with sensory function
-
Simone DA, Nolano M, Johnson T, Wendelschafer-Crabb G, and Kennedy WR (1998) Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: correlation with sensory function. J Neurosci 18:8947-8959
-
(1998)
J Neurosci
, vol.18
, pp. 8947-8959
-
-
Simone, D.A.1
Nolano, M.2
Johnson, T.3
Wendelschafer-Crabb, G.4
Kennedy, W.R.5
-
176
-
-
46049111268
-
Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy
-
NGX-4010 C107 Study Group
-
Simpson DM, Brown S, Tobias J, and NGX-4010 C107 Study Group (2008) Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy. Neurology 70:2305-2313
-
(2008)
Neurology
, vol.70
, pp. 2305-2313
-
-
Simpson, D.M.1
Brown, S.2
Tobias, J.3
-
177
-
-
0036662902
-
Stimulation of deep somatic tissue with capsaicin produces longlasting mechanical allodynia and heat hypoalgesia that depends on early activation of the CAMP pathway
-
Sluka KA (2002) Stimulation of deep somatic tissue with capsaicin produces longlasting mechanical allodynia and heat hypoalgesia that depends on early activation of the CAMP pathway. J Neurosci 22:5687-5693
-
(2002)
J Neurosci
, vol.22
, pp. 5687-5693
-
-
Sluka, K.A.1
-
178
-
-
0030908175
-
The effects of G-protein and protein kinase inhibitors on the behavioral responses of rats to intradermal injection of capsaicin
-
Sluka KA and Willis WD (1997) The effects of G-protein and protein kinase inhibitors on the behavioral responses of rats to intradermal injection of capsaicin. Pain 71:165-178
-
(1997)
Pain
, vol.71
, pp. 165-178
-
-
Sluka, K.A.1
Willis, W.D.2
-
179
-
-
0033623176
-
Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A
-
Smith JA, Davis CL, and Burgess GM (2000) Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A. Eur J Neurosci 12:3250-3258
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3250-3258
-
-
Smith, J.A.1
Davis, C.L.2
Burgess, G.M.3
-
181
-
-
77955387987
-
Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate
-
Sowa NA, Street SE, Vihko P, and Zylka MJ (2010) Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate. J Neurosci 30:10282-10293
-
(2010)
J Neurosci
, vol.30
, pp. 10282-10293
-
-
Sowa, N.A.1
Street, S.E.2
Vihko, P.3
Zylka, M.J.4
-
182
-
-
67649612716
-
The role of the TRPV1 endogenous agonist N-oleoyldopamine in modulation of nociceptive signaling at the spinal cord level
-
Spicarova D and Palecek J (2009) The role of the TRPV1 endogenous agonist N-oleoyldopamine in modulation of nociceptive signaling at the spinal cord level. J Neurophysiol 102:234-243
-
(2009)
J Neurophysiol
, vol.102
, pp. 234-243
-
-
Spicarova, D.1
Palecek, J.2
-
183
-
-
68449088888
-
Assessing analgesic actions of opioids by experimental pain models in healthy volunteers - an updated review
-
Staahl C, Olesen AE, Andresen T, Arendt-Nielsen L, and Drewes AM (2009a) Assessing analgesic actions of opioids by experimental pain models in healthy volunteers - an updated review. Br J Clin Pharmacol 68:149-168
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 149-168
-
-
Staahl, C.1
Olesen, A.E.2
Andresen, T.3
Arendt-Nielsen, L.4
Drewes, A.M.5
-
184
-
-
69949128268
-
Assessing efficacy of non-opioid analgesics in experimental pain models in healthy volunteers: An updated review
-
Staahl C, Olesen AE, Andresen T, Arendt-Nielsen L, and Drewes AM (2009b) Assessing efficacy of non-opioid analgesics in experimental pain models in healthy volunteers: an updated review. Br J Clin Pharmacol 68:322-341
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 322-341
-
-
Staahl, C.1
Olesen, A.E.2
Andresen, T.3
Arendt-Nielsen, L.4
Drewes, A.M.5
-
185
-
-
12144287525
-
Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures
-
Ständer S, Moormann C, Schumacher M, Buddenkotte J, Artuc M, Shpacovitch V, Brzoska T, Lippert U, Henz BM, Luger TA, et al. (2004) Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol 13:129-139
-
(2004)
Exp Dermatol
, vol.13
, pp. 129-139
-
-
Ständer, S.1
Moormann, C.2
Schumacher, M.3
Buddenkotte, J.4
Artuc, M.5
Shpacovitch, V.6
Brzoska, T.7
Lippert, U.8
Henz, B.M.9
Luger, T.A.10
-
186
-
-
37249040918
-
Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways
-
Starowicz K, Maione S, Cristino L, Palazzo E, Marabese I, Rossi F, de Novellis V, and Di Marzo V (2007) Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways. J Neurosci 27:13739-13749
-
(2007)
J Neurosci
, vol.27
, pp. 13739-13749
-
-
Starowicz, K.1
Maione, S.2
Cristino, L.3
Palazzo, E.4
Marabese, I.5
Rossi, F.6
de Novellis, V.7
Di Marzo, V.8
-
187
-
-
33750524257
-
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
-
Stein AT, Ufret-Vincenty CA, Hua L, Santana LF, and Gordon SE (2006) Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol 128:509-522
-
(2006)
J Gen Physiol
, vol.128
, pp. 509-522
-
-
Stein, A.T.1
Ufret-Vincenty, C.A.2
Hua, L.3
Santana, L.F.4
Gordon, S.E.5
-
188
-
-
0037434474
-
A comparison of hyperalgesia and neurogenic inflammation induced by melittin and capsaicin in humans
-
Sumikura H, Andersen OK, Drewes AM, and Arendt-Nielsen L (2003a) A comparison of hyperalgesia and neurogenic inflammation induced by melittin and capsaicin in humans. Neurosci Lett 337:147-150
-
(2003)
Neurosci Lett
, vol.337
, pp. 147-150
-
-
Sumikura, H.1
Andersen, O.K.2
Drewes, A.M.3
Arendt-Nielsen, L.4
-
189
-
-
33751549452
-
Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats
-
Sun R, Yan J, and Willis WD (2007) Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats. Neuroscience 144:286-294
-
(2007)
Neuroscience
, vol.144
, pp. 286-294
-
-
Sun, R.1
Yan, J.2
Willis, W.D.3
-
190
-
-
0037823484
-
The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin
-
Sun RQ, Lawand NB, and Willis WD (2003) The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. Pain 104:201-208
-
(2003)
Pain
, vol.104
, pp. 201-208
-
-
Sun, R.Q.1
Lawand, N.B.2
Willis, W.D.3
-
191
-
-
77952379134
-
Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats
-
Suresh D and Srinivasan K (2010) Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats. Indian J Med Res 131:682-691
-
(2010)
Indian J Med Res
, vol.131
, pp. 682-691
-
-
Suresh, D.1
Srinivasan, K.2
-
192
-
-
0009574128
-
Metabolism of capsaicinoids: Evidence for aliphatic hydroxylation and its pharmacological implications
-
Surh YJ, Ahn SH, Kim KC, Park JB, Sohn YW, and Lee SS (1995) Metabolism of capsaicinoids: evidence for aliphatic hydroxylation and its pharmacological implications. Life Sci 56:PL305-PL311
-
(1995)
Life Sci
, vol.56
-
-
Surh, Y.J.1
Ahn, S.H.2
Kim, K.C.3
Park, J.B.4
Sohn, Y.W.5
Lee, S.S.6
-
193
-
-
0032970173
-
Vanilloid (Capsaicin) receptors and mechanisms
-
Szallasi A and Blumberg PM (1999) Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol Rev 51:159-212
-
(1999)
Pharmacol Rev
, vol.51
, pp. 159-212
-
-
Szallasi, A.1
Blumberg, P.M.2
-
194
-
-
0028173216
-
Visualization by [3H]resiniferatoxin autoradiography of capsaicin-sensitive neurons in the rat, pig and man
-
Szallasi A, Blumberg PM, Nilsson S, Hökfelt T, and Lundberg JM (1994) Visualization by [3H]resiniferatoxin autoradiography of capsaicin-sensitive neurons in the rat, pig and man. Eur J Pharmacol 264:217-221
-
(1994)
Eur J Pharmacol
, vol.264
, pp. 217-221
-
-
Szallasi, A.1
Blumberg, P.M.2
Nilsson, S.3
Hökfelt, T.4
Lundberg, J.M.5
-
195
-
-
34248138496
-
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
-
Szallasi A, Cortright DN, Blum CA, and Eid SR (2007) The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 6:357-372
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 357-372
-
-
Szallasi, A.1
Cortright, D.N.2
Blum, C.A.3
Eid, S.R.4
-
196
-
-
0017640292
-
A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain
-
Szolcsanyi J (1977) A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain. J Physiol (Paris) 73:251-259
-
(1977)
J Physiol (Paris)
, vol.73
, pp. 251-259
-
-
Szolcsanyi, J.1
-
197
-
-
0000968168
-
Simple method for quantitation of capsaicinoids in peppers using capillary gas chromatography
-
Thomas BV, Schreiber AA, and Weisskopf CP (1998) Simple method for quantitation of capsaicinoids in peppers using capillary gas chromatography. J Agric Food Chem 46:2655-2663
-
(1998)
J Agric Food Chem
, vol.46
, pp. 2655-2663
-
-
Thomas, B.V.1
Schreiber, A.A.2
Weisskopf, C.P.3
-
198
-
-
33644796336
-
Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant
-
Tian W, Fu Y, Wang DH, and Cohen DM (2006) Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant. Am J Physiol Renal Physiol 290: F117-F126
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Tian, W.1
Fu, Y.2
Wang, D.H.3
Cohen, D.M.4
-
199
-
-
0035109136
-
Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity
-
Tohda C, Sasaki M, Konemura T, Sasamura T, Itoh M, and Kuraishi Y (2001) Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity. J Neurochem 76: 1628-1635
-
(2001)
J Neurochem
, vol.76
, pp. 1628-1635
-
-
Tohda, C.1
Sasaki, M.2
Konemura, T.3
Sasamura, T.4
Itoh, M.5
Kuraishi, Y.6
-
200
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, and Julius D (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21:531-543
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
201
-
-
26444511606
-
Structure and function of TRPV1
-
TominagaMand Tominaga T (2005) Structure and function of TRPV1 Pflugers Arch 451:143-150
-
(2005)
Pflugers Arch
, vol.451
, pp. 143-150
-
-
Tominagamand, T.T.1
-
202
-
-
0026534771
-
Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans
-
Torebjörk HE, Lundberg LE, and LaMotte RH (1992) Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans. J Physiol 448:765-780
-
(1992)
J Physiol
, vol.448
, pp. 765-780
-
-
Torebjörk, H.E.1
Lundberg, L.E.2
Lamotte, R.H.3
-
204
-
-
21844525787
-
Modern concepts of pain and hyperalgesia: Beyond the polymodal C-nociceptor
-
Treede RD and Magerl W (1995) Modern concepts of pain and hyperalgesia: beyond the polymodal C-nociceptor. News Physiol Sci 10:216-228
-
(1995)
News Physiol Sci
, vol.10
, pp. 216-228
-
-
Treede, R.D.1
Magerl, W.2
-
205
-
-
4544227074
-
Antitussive activity of iodo-resiniferatoxin in guinea pigs
-
Trevisani M, Milan A, Gatti R, Zanasi A, Harrison S, Fontana G, Morice AH, and Geppetti P (2004) Antitussive activity of iodo-resiniferatoxin in guinea pigs. Thorax 59:769-772
-
(2004)
Thorax
, vol.59
, pp. 769-772
-
-
Trevisani, M.1
Milan, A.2
Gatti, R.3
Zanasi, A.4
Harrison, S.5
Fontana, G.6
Morice, A.H.7
Geppetti, P.8
-
206
-
-
0028071153
-
Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: Study with online continuous monitoring of glutamate
-
Ueda M, Kuraishi Y, Sugimoto K, and Satoh M (1994) Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with online continuous monitoring of glutamate. Neurosci Res 20:231-237
-
(1994)
Neurosci Res
, vol.20
, pp. 231-237
-
-
Ueda, M.1
Kuraishi, Y.2
Sugimoto, K.3
Satoh, M.4
-
207
-
-
79953218015
-
Localization of the PIP2 sensor of TRPV1 ion channels
-
Ufret-Vincenty CA, Klein RM, Hua L, Angueyra J, and Gordon SE (2011) Localization of the PIP2 sensor of TRPV1 ion channels. J Biol Chem 286:9688-9698
-
(2011)
J Biol Chem
, vol.286
, pp. 9688-9698
-
-
Ufret-Vincenty, C.A.1
Klein, R.M.2
Hua, L.3
Angueyra, J.4
Gordon, S.E.5
-
208
-
-
0027933184
-
Modulation of spinal excitability: Co-operation between neurokinin and excitatory amino acid neurotransmitters
-
Urban L, Thompson SW, and Dray A (1994) Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci 17:432-438
-
(1994)
Trends Neurosci
, vol.17
, pp. 432-438
-
-
Urban, L.1
Thompson, S.W.2
Dray, A.3
-
209
-
-
0035939450
-
Vanilloid receptor VR1 is both presynaptic and postsynaptic in the superficial laminae of the rat dorsal horn
-
Valtschanoff JG, Rustioni A, Guo A, and Hwang SJ (2001) Vanilloid receptor VR1 is both presynaptic and postsynaptic in the superficial laminae of the rat dorsal horn. J Comp Neurol 436:225-235
-
(2001)
J Comp Neurol
, vol.436
, pp. 225-235
-
-
Valtschanoff, J.G.1
Rustioni, A.2
Guo, A.3
Hwang, S.J.4
-
210
-
-
7444225294
-
Functional bradykinin B1 receptors are expressed in nociceptive neurones and are upregulated by the neurotrophin GDNF
-
Vellani V, Zachrisson O, and McNaughton PA (2004) Functional bradykinin B1 receptors are expressed in nociceptive neurones and are upregulated by the neurotrophin GDNF. J Physiol 560:391-401
-
(2004)
J Physiol
, vol.560
, pp. 391-401
-
-
Vellani, V.1
Zachrisson, O.2
McNaughton, P.A.3
-
212
-
-
33750427895
-
TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low PH in HEK293 cells
-
Vos MH, Neelands TR, McDonald HA, Choi W, Kroeger PE, Puttfarcken PS, Faltynek CR, Moreland RB, and Han P (2006) TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low PH in HEK293 cells. J Neurochem 99:1088-1102
-
(2006)
J Neurochem
, vol.99
, pp. 1088-1102
-
-
Vos, M.H.1
Neelands, T.R.2
McDonald, H.A.3
Choi, W.4
Kroeger, P.E.5
Puttfarcken, P.S.6
Faltynek, C.R.7
Moreland, R.B.8
Han, P.9
-
213
-
-
4444258203
-
An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels
-
Wang C, Hu HZ, Colton CK, Wood JD, and Zhu MX (2004) An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. J Biol Chem 279:37423-37430
-
(2004)
J Biol Chem
, vol.279
, pp. 37423-37430
-
-
Wang, C.1
Hu, H.Z.2
Colton, C.K.3
Wood, J.D.4
Zhu, M.X.5
-
215
-
-
77952424787
-
Interactions of glutamate and capsaicin-evoked muscle pain on jaw motor functions of men
-
Wang K, Svensson P, Sessle BJ, Cairns BE, and Arendt-Nielsen L (2010) Interactions of glutamate and capsaicin-evoked muscle pain on jaw motor functions of men. Clin Neurophysiol 121:950-956
-
(2010)
Clin Neurophysiol
, vol.121
, pp. 950-956
-
-
Wang, K.1
Svensson, P.2
Sessle, B.J.3
Cairns, B.E.4
Arendt-Nielsen, L.5
-
216
-
-
2342519255
-
Interaction between histamine-induced itch and experimental muscle pain
-
Wasner G, Schwarz K, Schattschneider J, Binder A, Jensen TS, and Baron R (2004) Interaction between histamine-induced itch and experimental muscle pain. Eur J Pain 8:179-185
-
(2004)
Eur J Pain
, vol.8
, pp. 179-185
-
-
Wasner, G.1
Schwarz, K.2
Schattschneider, J.3
Binder, A.4
Jensen, T.S.5
Baron, R.6
-
217
-
-
79951977972
-
Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect
-
Watabiki T, Kiso T, Kuramochi T, Yonezawa K, Tsuji N, Kohara A, Kakimoto S, Aoki T, and Matsuoka N (2011) Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect. J Pharmacol Exp Ther 336:743-750
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 743-750
-
-
Watabiki, T.1
Kiso, T.2
Kuramochi, T.3
Yonezawa, K.4
Tsuji, N.5
Kohara, A.6
Kakimoto, S.7
Aoki, T.8
Matsuoka, N.9
-
218
-
-
84860389749
-
TRPV1, TRPA1, and CB1 in the isolated vagus nerve-axonal chemosensitivity and control of neuropeptide release
-
Weller K, Reeh PW, and Sauer SK (2011) TRPV1, TRPA1, and CB1 in the isolated vagus nerve-axonal chemosensitivity and control of neuropeptide release. Neuropeptides 45:391-400
-
(2011)
Neuropeptides
, vol.45
, pp. 391-400
-
-
Weller, K.1
Reeh, P.W.2
Sauer, S.K.3
-
219
-
-
1542317629
-
The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor
-
Willert RP, Woolf CJ, Hobson AR, Delaney C, Thompson DG, and Aziz Q (2004) The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor. Gastroenterology 126:683-692
-
(2004)
Gastroenterology
, vol.126
, pp. 683-692
-
-
Willert, R.P.1
Woolf, C.J.2
Hobson, A.R.3
Delaney, C.4
Thompson, D.G.5
Aziz, Q.6
-
220
-
-
0035038778
-
Role of neurotransmitters in sensitization of pain responses
-
Willis WD (2001) Role of neurotransmitters in sensitization of pain responses. Ann NY Acad Sci 933:142-156
-
(2001)
Ann NY Acad Sci
, vol.933
, pp. 142-156
-
-
Willis, W.D.1
-
221
-
-
0031404572
-
Central sensitization following intradermal injection of capsaicin
-
Willis WD (1997) Central sensitization following intradermal injection of capsaicin. Behav Brain Sci 20:471
-
(1997)
Behav Brain Sci
, vol.20
, pp. 471
-
-
Willis, W.D.1
-
222
-
-
0032504560
-
Differential effect of painful heterotopic stimulation on capsaicin-induced pain and allodynia
-
Witting N, Svensson P, Arendt-Nielsen L, and Jensen TS (1998) Differential effect of painful heterotopic stimulation on capsaicin-induced pain and allodynia. Brain Res 801:206-210
-
(1998)
Brain Res
, vol.801
, pp. 206-210
-
-
Witting, N.1
Svensson, P.2
Arendt-Nielsen, L.3
Jensen, T.S.4
-
223
-
-
0033967453
-
Intramuscular and intradermal injection of capsaicin: A comparison of local and referred pain
-
Witting N, Svensson P, Gottrup H, Arendt-Nielsen L, and Jensen TS (2000) Intramuscular and intradermal injection of capsaicin: a comparison of local and referred pain. Pain 84:407-412
-
(2000)
Pain
, vol.84
, pp. 407-412
-
-
Witting, N.1
Svensson, P.2
Gottrup, H.3
Arendt-Nielsen, L.4
Jensen, T.S.5
-
224
-
-
0025974775
-
The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states
-
Woolf CJ and Thompson SW (1991) The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain 44:293-299
-
(1991)
Pain
, vol.44
, pp. 293-299
-
-
Woolf, C.J.1
Thompson, S.W.2
-
225
-
-
36549004459
-
Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene
-
Xu H, Tian W, Fu Y, Oyama TT, Anderson S, and Cohen DM (2007) Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. Am J Physiol Renal Physiol 293:F1865-F1876
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Xu, H.1
Tian, W.2
Fu, Y.3
Oyama, T.T.4
Anderson, S.5
Cohen, D.M.6
-
226
-
-
33947200195
-
Transcription of rat TRPV1 utilizes a dual promoter system that is positively regulated by nerve growth factor
-
Xue Q, Jong B, Chen T, and Schumacher MA (2007) Transcription of rat TRPV1 utilizes a dual promoter system that is positively regulated by nerve growth factor. J Neurochem 101:212-222
-
(2007)
J Neurochem
, vol.101
, pp. 212-222
-
-
Xue, Q.1
Jong, B.2
Chen, T.3
Schumacher, M.A.4
-
227
-
-
84867083778
-
Substance P contributes to spinal cord central sensitization induced by capsaicin (Abstract)
-
Yan J, Sun R, Nie L, Hughes M, Dunsmore J, McAdoo D, and Willis W (2005) Substance P contributes to spinal cord central sensitization induced by capsaicin (Abstract). J Pain 6:S9
-
(2005)
J Pain
, vol.6
-
-
Yan, J.1
Sun, R.2
Nie, L.3
Hughes, M.4
Dunsmore, J.5
McAdoo, D.6
Willis, W.7
-
228
-
-
33750972053
-
Intradermal injection of capsaicin induces acute substance P release from rat spinal cord dorsal horn
-
Yan JY, Sun RQ, Hughes MG, McAdoo DJ, and Willis WD (2006) Intradermal injection of capsaicin induces acute substance P release from rat spinal cord dorsal horn. Neurosci Lett 410:183-186
-
(2006)
Neurosci Lett
, vol.410
, pp. 183-186
-
-
Yan, J.Y.1
Sun, R.Q.2
Hughes, M.G.3
McAdoo, D.J.4
Willis, W.D.5
-
229
-
-
0242367472
-
Activation of vanilloid receptor 1 (VR1) by eugenol
-
Yang BH, Piao ZG, Kim YB, Lee CH, Lee JK, Park K, Kim JS, and Oh SB (2003) Activation of vanilloid receptor 1 (VR1) by eugenol. J Dent Res 82:781-785
-
(2003)
J Dent Res
, vol.82
, pp. 781-785
-
-
Yang, B.H.1
Piao, Z.G.2
Kim, Y.B.3
Lee, C.H.4
Lee, J.K.5
Park, K.6
Kim, J.S.7
Oh, S.B.8
-
230
-
-
0032561203
-
Capsaicin facilitates excitatory but not inhibitory synaptic transmission in substantia gelatinosa of the rat spinal cord
-
Yang K, Kumamoto E, Furue H, and Yoshimura M (1998) Capsaicin facilitates excitatory but not inhibitory synaptic transmission in substantia gelatinosa of the rat spinal cord. Neurosci Lett 255:135-138
-
(1998)
Neurosci Lett
, vol.255
, pp. 135-138
-
-
Yang, K.1
Kumamoto, E.2
Furue, H.3
Yoshimura, M.4
-
231
-
-
0035962308
-
Vanilloid receptor 1 immunoreactivity in inflamed human bowel
-
Yiangou Y, Facer P, Dyer NH, Chan CL, Knowles C, Williams NS, and Anand P (2001) Vanilloid receptor 1 immunoreactivity in inflamed human bowel. Lancet 357:1338-1339
-
(2001)
Lancet
, vol.357
, pp. 1338-1339
-
-
Yiangou, Y.1
Facer, P.2
Dyer, N.H.3
Chan, C.L.4
Knowles, C.5
Williams, N.S.6
Anand, P.7
-
232
-
-
58749096723
-
The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant
-
Yu L, Yang F, Luo H, Liu FY, Han JS, Xing GG, and Wan Y (2008) The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant. Mol Pain 4:61
-
(2008)
Mol Pain
, vol.4
, pp. 61
-
-
Yu, L.1
Yang, F.2
Luo, H.3
Liu, F.Y.4
Han, J.S.5
Xing, G.G.6
Wan, Y.7
-
233
-
-
15244347057
-
A role for the brainstem in central sensitisation in humans. evidence from functional magnetic resonance imaging
-
Zambreanu L, Wise RG, Brooks JC, Iannetti GD, and Tracey I (2005) A role for the brainstem in central sensitisation in humans. evidence from functional magnetic resonance imaging. Pain 114:397-407
-
(2005)
Pain
, vol.114
, pp. 397-407
-
-
Zambreanu, L.1
Wise, R.G.2
Brooks, J.C.3
Iannetti, G.D.4
Tracey, I.5
-
234
-
-
29244484493
-
NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels
-
Zhang X, Huang J, and McNaughton PA (2005) NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. EMBO J 24:4211-4223
-
(2005)
EMBO J
, vol.24
, pp. 4211-4223
-
-
Zhang, X.1
Huang, J.2
McNaughton, P.A.3
-
235
-
-
33748690363
-
The effects of protein phosphatase inhibitors on the duration of central sensitization of rat dorsal horn neurons following injection of capsaicin
-
Zhang X, Wu J, Fang L, and Willis WD (2006) The effects of protein phosphatase inhibitors on the duration of central sensitization of rat dorsal horn neurons following injection of capsaicin. Mol Pain 2:23
-
(2006)
Mol Pain
, vol.2
, pp. 23
-
-
Zhang, X.1
Wu, J.2
Fang, L.3
Willis, W.D.4
-
236
-
-
0032730144
-
Secondary hyperalgesia to punctate mechanical stimuli. Central sensitization to A-fibre nociceptor input
-
Ziegler EA, Magerl W, Meyer RA, and Treede RD (1999) Secondary hyperalgesia to punctate mechanical stimuli. Central sensitization to A-fibre nociceptor input. Brain 122:2245-2257
-
(1999)
Brain
, vol.122
, pp. 2245-2257
-
-
Ziegler, E.A.1
Magerl, W.2
Meyer, R.A.3
Treede, R.D.4
-
237
-
-
0035801330
-
NMDA or non-NMDA receptor antagonists attenuate increased fos expression in spinal dorsal horn GABAergic neurons after intradermal injection of capsaicin in rats
-
Zou X, Lin Q, and Willis WD (2001) NMDA or non-NMDA receptor antagonists attenuate increased fos expression in spinal dorsal horn GABAergic neurons after intradermal injection of capsaicin in rats. Neuroscience 106:171-182
-
(2001)
Neuroscience
, vol.106
, pp. 171-182
-
-
Zou, X.1
Lin, Q.2
Willis, W.D.3
-
238
-
-
0037049239
-
Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats
-
Zou X, Lin Q, and Willis WD (2002) Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats. Neuroscience 115:775-786
-
(2002)
Neuroscience
, vol.115
, pp. 775-786
-
-
Zou, X.1
Lin, Q.2
Willis, W.D.3
-
239
-
-
4143110134
-
Effect of protein kinase C blockade on phosphorylation of NR1 in dorsal horn and spinothalamic tract cells caused by intradermal capsaicin injection in rats
-
Zou X, Lin Q, and Willis WD (2004) Effect of protein kinase C blockade on phosphorylation of NR1 in dorsal horn and spinothalamic tract cells caused by intradermal capsaicin injection in rats. Brain Res 1020:95-105
-
(2004)
Brain Res
, vol.1020
, pp. 95-105
-
-
Zou, X.1
Lin, Q.2
Willis, W.D.3
-
240
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sørgård M, Di Marzo V, Julius D, and Högestätt ED (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400:452-457.
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sørgård, M.5
Di Marzo, V.6
Julius, D.7
Högestätt, E.D.8
|